Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(1 prodotti)
- Caspasi(154 prodotti)
- FOXO1(2 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(137 prodotti)
- PDK(9 prodotti)
- PERK(23 prodotti)
- Chinasi di serina/treonina(18 prodotti)
- Survivin(14 prodotti)
- TNF(94 prodotti)
- c-RET(61 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6231 prodotti di "Apoptosi"
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Droxinostat
CAS:Droxinostat (NS 41080) is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3Formula:C11H14ClNO3Purezza:99.83%Colore e forma:SolidPeso molecolare:243.69RG7112
CAS:RG7112 (RO5045337) (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor.Formula:C38H48Cl2N4O4SPurezza:99.66% - 99.9%Colore e forma:SolidPeso molecolare:727.788-Bromo-cAMP sodium salt
CAS:8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) is a long-acting derivative of cyclic AMP. 8-Bromo-cAMP is an activator of cyclic AMP-dependent protein kinase.Formula:C10H10BrN5NaO6PPurezza:98% - 99.94%Colore e forma:Off-White PowderPeso molecolare:430.08C5 Lenalidomide
CAS:C5 Lenalidomide is an chemical weith inconclusive biological activity.Formula:C13H13N3O3Purezza:99.4%Colore e forma:SolidPeso molecolare:259.26Kinetin riboside
CAS:Kinetin riboside (N6-Furfuryladenosine) can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells(IC50 of 2.5 μM)Formula:C15H17N5O5Purezza:98.17%Colore e forma:White SolidPeso molecolare:347.33Dacomitinib
CAS:Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.Formula:C24H25ClFN5O2Purezza:99.4% - 99.72%Colore e forma:SolidPeso molecolare:469.94Ref: TM-T2483
1mg35,00€2mg50,00€5mg74,00€1mL*10mM (DMSO)74,00€10mg120,00€25mg170,00€50mg215,00€100mg334,00€200mg421,00€500mg692,00€Flupentixol dihydrochloride
CAS:Flupentixol dihydrochloride is used in therapy of schizophrenia as well as in anxiolytic and depressive disorders.Formula:C23H27Cl2F3N2OSPurezza:98.76% - >99.99%Colore e forma:White Or Off-White SolidPeso molecolare:507.43Shield-1
CAS:Shield-1 is a specific, high-affinity, and cell-permeable ligand for FK506-binding protein 12 (FKBP).Cost-effective and quality-assured.Formula:C42H56N2O10Purezza:99.08%Colore e forma:SolidPeso molecolare:748.9Ref: TM-T13884
1mg152,00€5mg334,00€1mL*10mM (DMSO)500,00€10mg532,00€25mg847,00€50mg1.153,00€100mg1.549,00€500mg3.087,00€Tazemetostat
CAS:Tazemetostat (EPZ6438): Oral EZH2 inhibitor, blocks histone H3K27 methylation, potential cancer therapy.Formula:C34H44N4O4Purezza:98.24% - ≥95%Colore e forma:SolidPeso molecolare:572.74Ref: TM-T1788
2mg34,00€5mg50,00€1mL*10mM (DMSO)63,00€10mg70,00€25mg87,00€50mg96,00€100mg144,00€500mg363,00€Nerol
CAS:Nerol (Neryl alcohol) is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmiasFormula:C10H18OPurezza:98.59%Colore e forma:Colorless Oily Liquid LiquidPeso molecolare:154.25Ricolinostat
CAS:Ricolinostat (Rocilinostat) is an orally bioavailable, specific inhibitor of histone deacetylase 6 (HDAC6) with potential antineoplastic activity.Formula:C24H27N5O3Purezza:97.17% - 99.76%Colore e forma:SolidPeso molecolare:433.5Thalidomide 4'-ether-alkylC2-amine hydrochloride
CAS:Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate.Formula:C15H16ClN3O5Purezza:98.56%Colore e forma:SolidPeso molecolare:353.76Sodium Demethylcantharidate
CAS:Sodium Demethylcantharidate (Sodium norcantharidin) is extracted from Mylabris phqlarata pallas and has potent antitumor activity.Formula:C8H9O5·NaPurezza:99.66% - ≥98%Colore e forma:SolidPeso molecolare:208.14BAY 61-3606 HCl
CAS:BAY 61-3606 HCl: a reversible Syk inhibitor, halts mast cell degranulation, cytokines, and sensitizes MCF-7 cells to TRAIL-induced apoptosis.Formula:C20H19ClN6O3Colore e forma:SolidPeso molecolare:426.86FB23-2
CAS:FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor(IC50 : 2.6 μM).Formula:C18H15Cl2N3O3Purezza:97.29% - ≥95%Colore e forma:SolidPeso molecolare:392.24Thalidomide-O-amido-C6-NH2 TFA
CAS:Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA), a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-basedFormula:C46H53F6N8O16Purezza:95.16%Colore e forma:SolidPeso molecolare:1087.95ICCB280
CAS:ICCB280 was capable of inducing differentiation and apoptosis of ATRA-resistant patient blasts strongly signify that the activity of this compound can overcomeFormula:C23H18N2O4Purezza:98.04%Colore e forma:SolidPeso molecolare:386.4Ref: TM-T8839
1mg49,00€5mg100,00€1mL*10mM (DMSO)110,00€10mg173,00€25mg281,00€50mg409,00€100mg572,00€200mg773,00€Phenoxyethanol
CAS:Phenoxyethanol (NSC-1864) is germicidal. It often used together with quaternary ammonium compounds.Formula:C8H10O2Purezza:99.47%Colore e forma:Clear To Practically Clear Colourless LiquidPeso molecolare:138.16NSC-87877 disodium
CAS:NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.Formula:C19H13N3O7S2·2NaPurezza:97.89%Colore e forma:SolidPeso molecolare:503.42Lenaldekar
CAS:Lenaldekar (LDK) inhibits T-cell expansion and autoimmune encephalomyelitis.Formula:C18H14N4Purezza:97.73%Colore e forma:SolidPeso molecolare:286.33Ref: TM-T24398
1mg64,00€1mL*10mM (DMSO)123,00€5mg129,00€10mg188,00€25mg299,00€50mg427,00€100mg575,00€200mg767,00€Hederacolchiside A1
CAS:Hederacolchiside A1 exhibits anti-leishmanial and anticancer activities by disrupting cell membranes and inducing apoptosis via the PI3K/Akt/mTOR pathway.Formula:C47H76O16Purezza:98.76% - 99.92%Colore e forma:SolidPeso molecolare:897.1Ref: TM-T2P2806
1mg46,00€5mg114,00€1mL*10mM (DMSO)161,00€10mg167,00€25mg268,00€50mg408,00€100mg587,00€200mg825,00€Bicyclol
CAS:Bicyclol is an oral anti-hepatitis drug, decreasing ALT/AST levels by 50% and inhibiting HBV/HCV, boosting efficacy with interferon/lamivudine/adefovir.
Formula:C19H18O9Purezza:99.64% - 99.85%Colore e forma:SolidPeso molecolare:390.34Calcium dobesilate
CAS:Calcium dobesilate(CaD) has angioprotective properties and protects endothelial cells partly by ameliorating HG induced inflammation.Formula:C6H5O5SCa0Purezza:98.39%Colore e forma:White Or Almost PowderPeso molecolare:229.2ZYN57939
CAS:ZYN57939 (MTR-106), an RNA polymerase I inhibitor, treats related diseases with a 0.855 μM IC50 against HT-29 cells.Formula:C28H27N7O2SPurezza:99.81%Colore e forma:SolidPeso molecolare:525.62CBL0137 hydrochloride
CAS:CBL0137 hydrochloride (Curaxin-137 hydrochloride) is an inhibitor of the histone chaperone FACT, which also activates p53 and inhibits NF-κB.Cost-effective and quality-assured.Formula:C21H25ClN2O2Purezza:99.35% - 99.86%Colore e forma:SolidPeso molecolare:372.88Trametinib (DMSO solvate)
CAS:Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a Highly Potent and Selective MEK Inhibitor that specifically inhibits MEK1/2(IC50 :2 nM)Formula:C28H29FIN5O5SPurezza:99.71% - 99.92%Colore e forma:SolidPeso molecolare:693.53TCS PrP Inhibitor 13
CAS:TCS PrP Inhibitor 13 (5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One) is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.Formula:C15H11N3O3Purezza:99.7%Colore e forma:SolidPeso molecolare:281.27Ref: TM-T23450
5mg35,00€1mL*10mM (DMSO)38,00€10mg55,00€25mg100,00€50mg156,00€100mg231,00€200mg329,00€Cladribine
CAS:Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.Formula:C10H12ClN5O3Purezza:99.58% - >99.99%Colore e forma:White Crystalline SolidPeso molecolare:285.69Talampanel
CAS:Talampanel (LY-300164), an oral selective AMPA receptor antagonist, exhibits anti-seizure and neuroprotective properties.Formula:C19H19N3O3Purezza:98.3%Colore e forma:SolidPeso molecolare:337.37ENMD-1068 hydrochloride
CAS:ENMD-1068 hydrochloride: selective PAR2 antagonist, counters liver fibrosis, hinders endometrial cell growth, and induces apoptosis in studies.Formula:C15H30ClN3O2Colore e forma:SolidPeso molecolare:319.87Glycochenodeoxycholic acid sodium salt
CAS:GCDCA, a bile acid-glycine salt, is a secondary bile acid from colonic microbes.Formula:C26H42NNaO5Purezza:95.48% - 99.82%Colore e forma:SolidPeso molecolare:471.61Birinapant
CAS:Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor ofFormula:C42H56F2N8O6Purezza:97.08% - ≥95%Colore e forma:SolidPeso molecolare:806.94Ref: TM-T6007
1mg34,00€2mg46,00€5mg70,00€1mL*10mM (DMSO)92,00€10mg109,00€25mg172,00€50mg250,00€100mg447,00€σ1 Receptor antagonist-1
CAS:σ1 Receptor antagonist-1 is a selective sigma 1 receptor antagonist.Formula:C21H23NOSPurezza:99.8%Colore e forma:SolidPeso molecolare:337.48IMM-01
CAS:IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actin
Formula:C12H17N3O2SPurezza:98.87%Colore e forma:SolidPeso molecolare:267.35Topotecan
CAS:Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.Formula:C23H23N3O5Purezza:96.14% - 98.23%Colore e forma:Light Yellow Needle Crystal Or Crystalline PowderPeso molecolare:421.45DRB
CAS:DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 range of 4-10 μM)
Formula:C12H12Cl2N2O4Purezza:99.46% - 99.83%Colore e forma:White To Off-White Crystalline SolidPeso molecolare:319.14Inauhzin
CAS:Inauhzin (INZ) reactivates p53, inhibits SIRT1, induces Y cell apoptosis without genotoxic stress (IC50=3 uM in A549).Formula:C25H19N5OS2Purezza:98% - 99.36%Colore e forma:SolidPeso molecolare:469.58Tenovin-6 Hydrochloride
CAS:Tenovin-6 HCl: Inhibits SIRT1 (21µM), SIRT2 (10µM), HDAC8; potent p53 activator.Formula:C25H35ClN4O2SPurezza:99.36%Colore e forma:SolidPeso molecolare:491.09Ref: TM-T8480
1mg39,00€2mg51,00€5mg70,00€1mL*10mM (DMSO)73,00€10mg88,00€25mg140,00€50mg226,00€100mg376,00€S-(5'-Adenosyl)-L-methionine tosylate
CAS:S-(5'-Adenosyl)-L-methionine tosylate (SAMe) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNAFormula:C22H30N6O8S2Purezza:80% - 98.18%Colore e forma:SolidPeso molecolare:570.64Azoramide
CAS:Azoramide, a small-molecule modulator, has the antidiabetic activity of unfolded protein response.Formula:C15H17ClN2OSPurezza:99.08% - 99.85%Colore e forma:SolidPeso molecolare:308.83Thalidomide-5-methyl
CAS:Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand. Thalidomide-5-methyl is used in the recruitment of CRBN protein.Formula:C14H12N2O4Purezza:99.48%Colore e forma:SolidPeso molecolare:272.26Ref: TM-T40503
1mg65,00€1mL*10mM (DMSO)130,00€5mg144,00€10mg210,00€25mg359,00€50mg504,00€100mg680,00€200mg919,00€AZD3759 hydrochloride
CAS:AZD3759 hydrochloride is an oral, CNS-penetrant EGFR inhibitor with IC50s of 0.2/0.3/0.2 nM.Formula:C22H24Cl2FN5O3Purezza:99.62%Colore e forma:SolidPeso molecolare:496.36Ref: TM-T4249
2mg34,00€5mg46,00€1mL*10mM (DMSO)49,00€10mg62,00€25mg94,00€50mg167,00€100mg265,00€200mg385,00€Ciprofloxacin hydrochloride monohydrate
CAS:Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) is a fluoroquinolone antibiotic with potent antibacterial activity.
Formula:C17H21ClFN3O4Purezza:99.23% - 99.85%Colore e forma:White Or Yellowish Crystalline PowderPeso molecolare:385.82Laquinimod
CAS:Laquinimod (LAQ) is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral
Formula:C19H17ClN2O3Purezza:98.42% - 98.84%Colore e forma:SolidPeso molecolare:356.8Tenovin-3
CAS:Tenovin-3 acts as a p53 activator.Formula:C18H21N3OSPurezza:99.72% - ≥95%Colore e forma:SolidPeso molecolare:327.44Demethoxycurcumin
CAS:Demethoxycurcumin: antioxidant, anti-inflammatory, anti-proliferative, anti-acanthamoebic, enhances chemo for resistant cancers, inhibits cancer pathways.Formula:C20H18O5Purezza:94.54% - 99.86%Colore e forma:SolidPeso molecolare:338.35Ref: TM-T6S1683
5mg42,00€10mg52,00€1mL*10mM (DMSO)52,00€25mg88,00€50mg149,00€100mg212,00€200mg314,00€A-419259
CAS:A-419259 (RK-20449) is an apoptosis inducer that selectively inhibits the Src family of kinases, including Src,LCK, and Lyn, with an IC50=3 to 9 nM.Formula:C29H34N6OPurezza:99.48%Colore e forma:SolidPeso molecolare:482.62Ro-3306
CAS:RO-3306: ATP-competitive CDK1 inhibitor, Ki 20 nM, >15x more selective than other human kinases.Formula:C18H13N3OS2Purezza:97.67% - 99.79%Colore e forma:SolidPeso molecolare:351.45PKD-IN-1 dihydrochloride (956121-30-5 free base)
CAS:CRT0066101 dihydrochloride is an inhibitor of PKD.Formula:C18H21Cl3N4OPurezza:99.5%Colore e forma:SolidPeso molecolare:415.75Tauroursodeoxycholate
CAS:Tauroursodeoxycholate (UR 906), a hydrophilic bile acid, low in humans, may treat PBC, insulin resistance, and ALS.Formula:C26H45NO6SPurezza:98.77% - 99.93%Colore e forma:White SolidPeso molecolare:499.7
