Apoptosi

Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.

Sottocategorie di "Apoptosi"

Mostrare 6 più sottocategorie

Trovati 5592 prodotti di "Apoptosi"

Purezza (%)

100

prodotti per pagina.

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Ro 90-7501
CAS:
- 293762-45-5
Ro 90-7501, an amyloid β42 (Aβ42) protofibril and TPR-dependent PP5 inhibitor, is a novel cervical cancer cell radiosensitizer that inhibits HCMV.
Formula:C₂₀H₁₆N₆
Purezza:97.21% - 99.72%
Colore e forma:Solid
Peso molecolare:340.38
Ref: TM-T16773
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Pyrazoloacridine
CAS:
- 99009-20-8
Pyrazoloacridine (PD 115934) binds DNA, inhibits topo I/II, has 1.25 μM IC50 in K562 cells, and exhibits anti-cancer effects.
Formula:C₁₉H₂₁N₅O₃
Purezza:99.72%
Colore e forma:Solid
Peso molecolare:367.4
Ref: TM-T28475
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HS-276
CAS:
- 2767422-72-8
HS-276, a selective oral TAK1 inhibitor (Ki: 2.5 nM), also targets CLK2, GCK, ULK2, MAP4K5; potential for RA research.
Formula:C₂₄H₂₉N₅O₂
Purezza:97.852% - 98.81%
Colore e forma:Solid
Peso molecolare:419.52
Ref: TM-T62209
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CA-170
CAS:
- 1673534-76-3
PD-1-IN-1 is a programmed cell dealth-1inhibitor. PD-1-IN-1 can be used as an immune modulator.
Formula:C₁₂H₂₀N₆O₇
Purezza:98%
Colore e forma:Solid
Peso molecolare:360.32
Ref: TM-T12378L
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MY-673
CAS:
- 2944459-96-3
MY-673, a colchicine binding site inhibitor (CBSI), impedes tubulin polymerization and disrupts the ERK signaling pathway, consequently modulating SMAD4 protein
Formula:C₁₈H₁₄N₂O₄
Colore e forma:Solid
Peso molecolare:322.31
Ref: TM-T78798
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MRT199665
CAS:
- 1456858-57-3
MRT199665, a selective MARK/SIK/AMPK inhibitor, blocks SIK CRTC3 S370 phosphorylation and triggers apoptosis in AML cells.
Formula:C₂₈H₃₁N₅O₂
Colore e forma:Solid
Peso molecolare:469.58
Ref: TM-T16142
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2-Chlorophenoxazine
CAS:
- 56821-03-5
2-Chlorophenoxazine is an Akt inhibitor that demonstrates an in vitro inhibitory concentration (IC50) of 2-5 μM and has the capacity to induce apoptosis.
Formula:C₁₂H₈ClNO
Purezza:98%
Colore e forma:Solid
Peso molecolare:217.65
Ref: TM-T79722
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SF5
CAS:
- 34634-22-5
SF5 is an inhibitor of the apoptosis pathway through JNK-p53-caspase apoptotic cascade.
Formula:C₁₅H₁₃NS
Purezza:99.59%
Colore e forma:Solid
Peso molecolare:239.34
Ref: TM-T24784
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(Rac)-Lisaftoclax
CAS:
- 2651980-10-6
(Rac)-Lisaftoclax ((Rac)-APG-2575), a Bcl-2 inhibitor, is utilized in hematologic malignancy research (CN112898295A) [1].
Formula:C₄₅H₄₈ClN₇O₈S
Colore e forma:Solid
Peso molecolare:882.42
Ref: TM-T84730
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FOXO1-IN-3
CAS:
- 2451093-95-9
FOXO1-IN-3 is a highly-selective, orally active inhibitor of FOXO1 that diminishes hepatic glucose production and enhances insulin sensitivity and glucose
Formula:C₂₂H₂₃N₇O
Purezza:98%
Colore e forma:Solid
Peso molecolare:401.46
Ref: TM-T78187
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NWP-0476
CAS:
- 2290611-26-4
NWP-0476 is a modified BCL-2/BCL-xL inhibitor with enhanced specificity for BCL-xL, suitable for research on relapsed T-acute lymphoblastic leukemia (T-ALL) [1
Formula:C₄₇H₅₃ClN₈O₈S
Colore e forma:Solid
Peso molecolare:925.49
Ref: TM-T79377
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RMC-4998
CAS:
- 2642037-07-6
RMC-4998 is an orally available KRASG12C mutant inhibitor that targets the active or GTP-bound state of the KRASG12C mutant,inhibit ERK and apoptosis.
Formula:C₅₇H₇₄N₈O₇
Purezza:99.11%
Colore e forma:Solid
Peso molecolare:983.25
Ref: TM-T79870
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FHND5071
CAS:
- 2761152-16-1
FHND5071, a potent and selective RET kinase inhibitor, exerts antitumor effects through the inhibition of RET autophosphorylation and may be utilized for tumor
Formula:C₃₀H₃₀D₃N₉O
Colore e forma:Solid
Peso molecolare:538.66
Ref: TM-T78797
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RET-IN-5
CAS:
- 2725770-20-5
RET-IN-5 is a potent inhibitor of RET (IC50: 4.57 nM).
Formula:C₂₉H₂₆FN₉O
Colore e forma:Solid
Peso molecolare:535.57
Ref: TM-T63772
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INI-43
CAS:
- 881046-01-1
INI-43 targets Kpnβ1, disrupting nuclear transport in cervical/esophageal cancers, affecting NFAT, NFκB, AP-1, NF localization.
Formula:C₂₂H₂₃N₇
Purezza:99.83%
Colore e forma:Solid
Peso molecolare:385.46
Ref: TM-T27612
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p-Tolylmaleimide
CAS:
- 1631-28-3
p-Tolylmaleimide (p Tolylmaleimide) is an inhibitor of the water channel and binds to Aquaporin Z.
Formula:C₁₁H₉NO₂
Purezza:99.94%
Colore e forma:Solid
Peso molecolare:187.19
Ref: TM-T21044
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Artonin E
CAS:
- 129683-93-8
Artonin E, a prenylated flavonoid, induces apoptosis and S-phase arrest, disrupting the mitochondrial pathway for cancer research.
Formula:C₂₅H₂₄O₇
Colore e forma:Solid
Peso molecolare:436.45
Ref: TM-T73228
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Merodantoin
CAS:
- 143413-73-4
Merodantoin induces apoptosis in KRAS-mutant cancer cells via ROS-autophagy and Akt pathway.
Formula:C₁₁H₁₈N₂O₂S
Purezza:99.8%
Colore e forma:Solid
Peso molecolare:242.34
Ref: TM-T33296
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Ginsenoside Rk1
CAS:
- 494753-69-4
Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.
Formula:C₄₂H₇₀O₁₂
Purezza:98.46% - 99.13%
Colore e forma:Solid
Peso molecolare:767
Ref: TM-T4S1499
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SC 67655
CAS:
- 182134-00-5
SC 67655 is a peptidomimetic that specifically suppresses human leukocyte antigen DRB10401-restricted T cell proliferation.
Formula:C₃₇H₆₂N₆O₉
Purezza:98%
Colore e forma:Solid
Peso molecolare:734.92
Ref: TM-T26179