Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(6 prodotti)
- BCL(11 prodotti)
- Caspasi(125 prodotti)
- FOXO1(3 prodotti)
- IAP(66 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(125 prodotti)
- PDK(9 prodotti)
- PERK(25 prodotti)
- Chinasi di serina/treonina(15 prodotti)
- Survivin(13 prodotti)
- TNF(92 prodotti)
- c-RET(51 prodotti)
- p53(62 prodotti)
Mostrare 6 più sottocategorie
Trovati 5593 prodotti di "Apoptosi"
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Atiprimod dimaleate
CAS:<p>Atiprimod Dimaleate is a JAK2 inhibitor.</p>Formula:C30H52N2O8Colore e forma:SolidPeso molecolare:568.74(S)-Verapamil hydrochloride
CAS:(S)-Verapamil hydrochloride is an inhibitor of leukotriene C4 (LTC4) and calcein transport by MRP1,and leads to the death of potentially resistant tumor cells.Formula:C27H39ClN2O4Colore e forma:SolidPeso molecolare:491.06RUNX-IN-1
CAS:<p>RUNX-IN-1, also known as Compound Conjugate 1, covalently attaches to RUNX-binding sequences, thereby preventing RUNX proteins from associating with their</p>Formula:C71H88Cl2N24O11Purezza:98%Colore e forma:SolidPeso molecolare:1524.52USP7-IN-3
CAS:<p>USP7-IN-3 is a potent and selective allosteric inhibitor of ubiquitin-specific protease 7 (USP7).</p>Formula:C29H31F3N6O3Purezza:98%Colore e forma:SolidPeso molecolare:568.59AM-8735
CAS:<p>AM-8735 is an inhibitor of MDM2 ( IC50: 25 nM).</p>Formula:C27H31Cl2NO6SPurezza:98%Colore e forma:SolidPeso molecolare:568.51MTP
CAS:<p>MTP, a PKM2 inhibitor, promotes apoptosis in cancer cells via caspase-3 activation while also inducing autophagy and enhancing ROS generation.</p>Formula:C29H23F3N4O2Purezza:98%Colore e forma:SolidPeso molecolare:516.51HDAC-IN-59
CAS:<p>HDAC-IN-59 (compound 13a), a potent histone deacetylase (HDAC) inhibitor, enhances intracellular reactive oxygen species (ROS) production, induces DNA damage,</p>Formula:C20H25NO7Purezza:98%Colore e forma:SolidPeso molecolare:391.42RET-IN-25
CAS:<p>RET-IN-25 (compound 6b) is an anticancer RET kinase inhibitor that demonstrates efficacy against medullary thyroid carcinoma (MTC), exhibiting half-maximal</p>Formula:C22H17N3O5SColore e forma:SolidPeso molecolare:435.45RET-IN-5
CAS:<p>RET-IN-5 is a potent inhibitor of RET (IC50: 4.57 nM).</p>Formula:C29H26FN9OColore e forma:SolidPeso molecolare:535.57INI-43
CAS:<p>INI-43 targets Kpnβ1, disrupting nuclear transport in cervical/esophageal cancers, affecting NFAT, NFκB, AP-1, NF localization.</p>Formula:C22H23N7Purezza:99.83%Colore e forma:SolidPeso molecolare:385.46p-Tolylmaleimide
CAS:<p>p-Tolylmaleimide (p Tolylmaleimide) is an inhibitor of the water channel and binds to Aquaporin Z.</p>Formula:C11H9NO2Purezza:99.94%Colore e forma:SolidPeso molecolare:187.19Artonin E
CAS:<p>Artonin E, a prenylated flavonoid, induces apoptosis and S-phase arrest, disrupting the mitochondrial pathway for cancer research.</p>Formula:C25H24O7Colore e forma:SolidPeso molecolare:436.4515-Deoxy-Δ12,14-prostaglandin A1
CAS:<p>15-Deoxy-Δ12,14-Prostaglandin A1, a deoxyanalog of prostaglandins, inhibits NF-κB signaling and induces apoptosis. It also prevents TNF-α-induced upregulation of inflammatory endothelial cell adhesion molecules (CAM) and reduces monocyte arrest [1].</p>Formula:C20H30O3Colore e forma:SolidPeso molecolare:318.457Ezatiostat hydrochloride
CAS:<p>Ezatiostat HCl (TLK199) inhibits glutathione S-transferase, GSTP1-1 specifically, and may treat cytopenias.</p>Formula:C27H36ClN3O6SPurezza:98%Colore e forma:SolidPeso molecolare:566.11SM-433
CAS:<p>SM-433: Smac mimetic, blocks IAPs, strong XIAP BIR3 affinity (IC50 <1 μM). See patent WO2008128171A2.</p>Formula:C32H43N5O4Colore e forma:SolidPeso molecolare:561.71HDAC1/CDK7-IN-1
CAS:<p>HDAC1/CDK7-IN-1 (compound 8e) serves as a dual inhibitor targeting both CDK7 and HDAC1, with IC50 values of 893 nM and 248 nM , respectively.</p>Formula:C33H32ClN7O4Purezza:98%Colore e forma:SolidPeso molecolare:626.11PLK1/BRD4-IN-1
CAS:<p>PLK1/BRD4-IN-1 (9b) is an orally active dual inhibitor of PLK1 (IC50: 22 nM) and BRD4 (IC50: 109 nM).</p>Formula:C31H43N9O2Colore e forma:SolidPeso molecolare:573.73BAI1 hydrochloride
CAS:<p>BAI1 hydrochloride is a selective inhibitor of the apoptosis factor BAX, functioning through an allosteric mechanism. By binding to BAX, it allosterically inhibits its activation, showcasing potential applications in the research of diseases mediated by BAX-dependent cell death [1].</p>Formula:C19H23Br2Cl2N3OColore e forma:SolidPeso molecolare:540.12Delmitide acetate
CAS:<p>Delmitide acetate (RDP58) is an orally active d-isomer decapeptide that exhibits potent anti-inflammatory properties.</p>Formula:C61H109N17O13Purezza:98%Colore e forma:SolidPeso molecolare:1288.62YM281
CAS:<p>YM281 is a potent EZH2 inhibitor, causes apoptosis and G0/G1 arrest, has antitumor activity in vivo, and may be researched for lymphoma.</p>Formula:C56H71N7O9SColore e forma:SolidPeso molecolare:1018.27
