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Apoptosi

Apoptosi

Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.

Sottocategorie di "Apoptosi"

Mostrare 6 più sottocategorie

Trovati 5593 prodotti di "Apoptosi"

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  • Z-LLY-FMK
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    Z-LLY-FMK

    CAS:
    <p>Z-LLY-FMK (Calpain Inhibitor IV) serves as an inhibitor of calpain, a family of proteases implicated in the apoptosis of various cell systems.</p>
    Formula:C30H40FN3O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:557.65

    Ref: TM-T78632

  • RMC-4998
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    RMC-4998

    CAS:
    <p>RMC-4998 is an orally available KRASG12C mutant inhibitor that targets the active or GTP-bound state of the KRASG12C mutant,inhibit ERK and apoptosis.</p>
    Formula:C57H74N8O7
    Purezza:99.11%
    Colore e forma:Solid
    Peso molecolare:983.25

    Ref: TM-T79870

  • Lepadin E
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    Lepadin E

    CAS:
    <p>Lepadin E, a notably cytotoxic compound, effectively stimulates ferroptosis via the canonical p53-SLC7A11-GPX4 pathway.</p>
    Formula:C26H47NO3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:421.66

    Ref: TM-T79638

  • WNY1613
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    WNY1613

    CAS:
    <p>WNY1613: Potent PI3Kδ inhibitor with anti-NHL properties, induces apoptosis in cells, affects phosphorylation in vitro/in vivo.</p>
    Formula:C29H35N9O3
    Colore e forma:Solid
    Peso molecolare:557.65

    Ref: TM-T63942

  • Agerafenib hydrochloride
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    Agerafenib hydrochloride

    CAS:
    <p>Agerafenib hydrochloride is a highly potent inhibitor of BRAFV600E (Kd: 14 nM).</p>
    Formula:C24H23ClF3N5O5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:553.92

    Ref: TM-T14928

  • AR420626
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    AR420626

    CAS:
    <p>AR420626: selective FA3R agonist, guards against SALS, effects blocked by BHB, a FA3R antagonist.</p>
    Formula:C21H18Cl2N2O3
    Purezza:98.62%
    Colore e forma:Solid
    Peso molecolare:417.29

    Ref: TM-T26647

  • Ataquimast
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    Ataquimast

    CAS:
    <p>Ataquimast is used in curing advanced receptor-positive breast cancer.</p>
    Formula:C11H14ClN3O
    Purezza:99.92%
    Colore e forma:Solid
    Peso molecolare:239.7

    Ref: TM-T30190

  • CRT0066101 hydrochloride
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    CRT0066101 hydrochloride

    CAS:
    <p>Protein kinase D (PKD), a serine/threonine protein kinase activated by diacylglycerol downstream of PKC signaling, has three human isoforms that modulate cell proliferation, survival, invasion, and protein transport. CRT0066101 acts as an inhibitor of these three PKD isoforms, with IC50 values of 1, 2.5, and 2 nM for PKD1, PKD2, and PKD3, respectively. It demonstrates selectivity for PKD over a range of more than 90 protein kinases, including PKCα, PKBα, MEK, ERK, c-Raf, c-Src, and c-Abl. This specificity allows CRT0066101 to inhibit cell proliferation, induce apoptosis, and notably reduce the viability of pancreatic cancer cells both in vitro and in vivo.</p>
    Formula:C18H23ClN6O
    Colore e forma:Solid
    Peso molecolare:374.87

    Ref: TM-T84405

  • Ogremorphin
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    Ogremorphin

    CAS:
    <p>Ogremorphin (GPR68-IN-1) is a potent inhibitor of GPR68, exhibiting an EC50 of 170 nM.it is utilized in the study of autoimmune chronic inflammatory diseases [1</p>
    Formula:C21H17N3OS
    Purezza:99.65% - 99.65%
    Colore e forma:Solid
    Peso molecolare:359.44

    Ref: TM-T79209

  • Sirt1/2-IN-3
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    Sirt1/2-IN-3

    CAS:
    <p>Sirt1/2-IN-3 (compound PS9) serves as a dual inhibitor of SIRT1/2, exhibiting IC50 values of 1.4 μM (SIRT1) and 2.0 μM (SIRT2), respectively.</p>
    Formula:C17H14ClNO4S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:363.82

    Ref: TM-T79564

  • HDAC-IN-50
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    HDAC-IN-50

    CAS:
    <p>HDAC-IN-50, a potent FGFR/HDAC inhibitor (IC50: 0.18-13 nM), induces apoptosis, cell cycle arrest, and shows anti-tumor activity.</p>
    Formula:C31H41N7O4
    Colore e forma:Solid
    Peso molecolare:575.7

    Ref: TM-T73179

  • INCB3619
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    INCB3619

    CAS:
    <p>INCB3619 is a selective and potent inhibitor of ADAM with antitumour effects, inhibiting ADAM10, ADAM17, MMP12 and MMP15.</p>
    Formula:C22H27N3O5
    Purezza:98.41% - 99.51%
    Colore e forma:Solid
    Peso molecolare:413.47

    Ref: TM-T27603

  • Famitinib malate
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    Famitinib malate

    CAS:
    <p>Famitinib malate (SHR1020) is a potent oral kinase inhibitor targeting c-kit, VEGFR-2, and PDGFRβ, with IC50s 2.3, 4.7, 6.6 nM, useful for cancer research.</p>
    Formula:C27H33FN4O7
    Colore e forma:Solid
    Peso molecolare:544.57

    Ref: TM-T71111

  • TG2-179-1
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    TG2-179-1

    CAS:
    <p>Nalmefene (ORF 11676) is a μ-opioid antagonist and partial κ agonist used to study opioid overdose and alcohol dependence.</p>
    Formula:C22H14ClFN4O2S2
    Colore e forma:Solid
    Peso molecolare:484.95

    Ref: TM-T83855

  • Mcl-1 inhibitor 13
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    Mcl-1 inhibitor 13

    CAS:
    <p>Mcl-1 Inhibitor 13 (Example 9), with a Ki of 8.2 nM, serves as an MCL-1 inhibitor suitable for cancer research [1].</p>
    Formula:C47H45ClFN7O6
    Colore e forma:Solid
    Peso molecolare:858.35

    Ref: TM-T79036

  • RET-IN-25
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    RET-IN-25

    CAS:
    <p>RET-IN-25 (compound 6b) is an anticancer RET kinase inhibitor that demonstrates efficacy against medullary thyroid carcinoma (MTC), exhibiting half-maximal</p>
    Formula:C22H17N3O5S
    Colore e forma:Solid
    Peso molecolare:435.45

    Ref: TM-T79726

  • BRD4 Inhibitor-18
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    BRD4 Inhibitor-18

    CAS:
    <p>BRD4 Inhibitor-18: potent (IC50: 110 nM), impairs MV-4-11 cell growth, disrupts G0/G1 phase, and induces apoptosis.</p>
    Formula:C26H26ClN3O3S
    Colore e forma:Solid
    Peso molecolare:496.02

    Ref: TM-T63352

  • Estrogen receptor modulator 10
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    Estrogen receptor modulator 10

    CAS:
    <p>Compound G-5b, an estrogen receptor modulator 10, functions as an estrogen receptor (ER) antagonist (IC50=6.7 nM) and degrader (DC50=0.4 nM).</p>
    Formula:C32H37F9N4O3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:728.71

    Ref: TM-T82439

  • Zn(BQTC)
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    Zn(BQTC)

    CAS:
    <p>Zn(BQTC) inhibits mtDNA and nDNA, damages mitochondria/nuclei, triggers apoptosis, and targets A549R cancer cells.</p>
    Formula:C30H36Cl2N5O3Zn
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:650.92

    Ref: TM-T73367

  • RET-IN-13
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    RET-IN-13

    CAS:
    <p>RET-IN-13: potent quinoline RET inhibitor; IC50 = 0.5 nM (WT), 0.9 nM (V804M); potential for RET-related tumor/intestinal disease research.</p>
    Formula:C32H33F4N5O3
    Colore e forma:Solid
    Peso molecolare:611.63

    Ref: TM-T73248