Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(1 prodotti)
- Caspasi(154 prodotti)
- FOXO1(2 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(127 prodotti)
- PDK(9 prodotti)
- PERK(23 prodotti)
- Chinasi di serina/treonina(17 prodotti)
- Survivin(14 prodotti)
- TNF(90 prodotti)
- c-RET(61 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6170 prodotti di "Apoptosi"
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Pantinin-1
CAS:Pantinin-1 is an antimicrobial peptide found in the venom of the emperor scorpion (Pandinus imperator). This compound exhibits strong antibacterial activity against Gram-positive bacteria and fungi, but has weaker effects on Gram-negative bacteria. Additionally, Pantinin-1 demonstrates very low hemolytic activity on human red blood cells and possesses anticancer properties, specifically inducing apoptosis in tumor cells.Formula:C75H119N17O18Colore e forma:SolidPeso molecolare:1546.85MKC-1
CAS:MKC-1 (Ro-31-7453) is an oral bisindolylmaleimide inhibitor that disrupts tubulin polymerization, potentially halting cancer cell division.Formula:C22H16N4O4Purezza:99.63% - 99.85%Colore e forma:SolidPeso molecolare:400.39Ref: TM-T9831
1mg54,00€5mg118,00€10mg168,00€25mg293,00€50mg423,00€100mg588,00€500mgPrezzo su richiesta1mL*10mM (DMSO)127,00€BRD4 Inhibitor-39
BRD4 Inhibitor-39 (compound 12m) is an orally active inhibitor of BRD4 with an IC50 of 0.02 μM. It can induce apoptosis and demonstrates antitumor activity.Formula:C24H19BrFN9Colore e forma:SolidPeso molecolare:532.37Z-WEHD-FMK
CAS:Z-WEHD-FMK is a cell-permeable and irreversible inhibitor of caspase-1/5. It also shows a robust inhibitory effect on cathepsin B activity (IC50: 6 μM).Formula:C37H42FN7O10Purezza:98%Colore e forma:SolidPeso molecolare:763.78MS105
CAS:MS105 is an orally active, selective protein tyrosine kinase 6 (PTK6) PROTAC degrader. It recruits the VHL E3 ligase through a VHL ligand fragment, facilitating ubiquitination and proteasomal degradation of PTK6, thereby inhibiting the proliferation and migration of breast cancer cells and inducing apoptosis (apoptosis). MS105 is a promising compound for breast cancer research.Formula:C56H70FN13O6SColore e forma:SolidPeso molecolare:1072.30ADPM06
CAS:ADPM06: nonporphyrin PDT agent; leads in apoptosis, strong IC50 in µM against human tumors.Formula:C34H24BBr2F2N3O2Colore e forma:SolidPeso molecolare:715.19PROTAC GPX4 degrader-4
CAS:PROTACGPX4 degrader-4 is a GPX4 PROTAC degrader with a DC50 of 5.32 nM. It inhibits the activity of cancer cell lines RT4, T24, and J82 with IC50 values of 0.09, 2.97, and 7.58 μM, respectively. This compound elevates lipid ROS levels and induces ferroptosis in T24 and RT4 cells. In T24 tumor-bearing BALB/c nude mouse models, PROTACGPX4 degrader-4 demonstrates antitumor activity. It is applicable to bladder cancer research.Formula:C43H58N2O13Colore e forma:SolidPeso molecolare:810.93Sterigmatocystine
CAS:Sterigmatocystine, a G1 phase and DNA synthesis inhibitor, curbs p21 and is a mycotoxin precursor from Aspergillus versicolor.Formula:C18H12O6Purezza:98%Colore e forma:Pale-Yellow Crystals Pale Yellow SolidPeso molecolare:324.28fac-[Re(CO)3(L3)(H2O)][NO3]
Fac-[Re(CO)3(L3)(H2O)][NO3] (Compound 3), a rhenium(I) tricarbonyl aqua complex, acts as an anticancer agent through the induction of mitochondrial dysfunction.Formula:C25H17N6O8ReColore e forma:SolidPeso molecolare:715.64Thalidomide-Piperazine 5-fluoride hydrochloride
CAS:Thalidomide-Piperazine 5-fluoride hydrochloride, a derivative of the cereblon (CRBN) inhibitor Thalidomide, serves as a ligand for E3 ubiquitin ligase (Ligands for E3 Ligase), facilitating the synthesis of PROTACs [1].Formula:C17H18ClFN4O4Colore e forma:SolidPeso molecolare:396.8MEDI-7352
MEDI-7352 is a human bispecific antibody targeting NGF/bNGF and TNF. It can be utilized in research focused on osteoarthritis (OA) pain.Colore e forma:Odour LiquidVonlerolizumab
CAS:Vonlerolizumab (MOXR 0916) is a humanized IgG OX40 agonist monoclonal antibody with potential in cancer and immune disease research.Purezza:SDS-PAGE:97.3%;SEC-HPLC:99.4%Colore e forma:LiquidPeso molecolare:145.25 kDaFerroptosis-IN-14
Ferroptosis-IN-14 (compund 36) exhibits the most potent anti-ferroptotic activity with an EC50 value of 0.58 ± 0.02 μM, demonstrating excellent anti-ferroptotic efficacy, as well as stability in microsomes and plasma.Colore e forma:Odour SolidBAY 1892005
CAS:BAY 1892005 is a p53 protein modulator that targets the p53 condenser for the study of diseases associated with misfolded p53 proteinFormula:C11H8ClFN2OSPurezza:99.42%Colore e forma:SoildPeso molecolare:270.71Ac-IEPD-AFC
CAS:Ac-IEPD-AFC (IEPD) is a fluorescent substrate for granzyme B and can be used to measure granzyme B activity.Formula:C32H38F3N5O11Purezza:99.16%Colore e forma:SolidPeso molecolare:725.67BK60106
BK60106 is a selective and direct inhibitor of the transmembrane protein CD99, which causes cell death in Ewing Sarcoma cells.Formula:C15H15FN6O3Purezza:99.30% - >99.99%Colore e forma:SolidPeso molecolare:346.32BRAFV600E/JNK-IN-1
BRAFV600E/JNK-IN-1 (Compound 14c) is an inhibitor of JNK1, JNK2, JNK3, and BRAFV600E, with IC50 values of 0.51 μM, 0.53 μM, 1.02 μM, and 0.009 μM, respectively. It also inhibits the phosphorylation of MEK1/2 and ERK1/2. Additionally, BRAFV600E/JNK-IN-1 suppresses tumor cell proliferation, NO release, and PGE2 production, exhibiting both antitumor and anti-inflammatory activities.Colore e forma:Odour SolidLeucettamol A
CAS:Leucettamol A, from Leucetta microraphis, blocks LTB4 receptor and prevents Ubc13-Uev1A complex formation.Formula:C30H52N2O2Purezza:98%Colore e forma:SolidPeso molecolare:472.758Emavusertib hydrochloride
CAS:Emavusertib (CA-4948) hydrochloride, a selective and potent IRAK4/FLT3 inhibitor, is designed for oral administration. It achieves an IC 50 of 57 nM against IRAK4 in a FRET kinase assay and demonstrates anti-tumor activity [1] [2] [3].Formula:C24H26ClN7O5Colore e forma:SolidPeso molecolare:527.96Annonacin
CAS:Annonacin is a cytotoxic acetogenin in Graviola leaf extract; it blocks mitochondrial complex and inhibits NKA/SERCA ATPase pumps.Formula:C35H64O7Purezza:98%Colore e forma:SolidPeso molecolare:596.88
