Apoptosi

Hexamethonium Bromide blocks neural nicotinic AChR, poorly absorbed in the gut, doesn't pass the blood-brain barrier.

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse GDF15. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse GDF15. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse GDF15, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse GDF15 in the samples is then determined by comparing the OD of the samples to the standard curve.

Risedronate Sodium treats osteoporosis; it's an etidronic acid derivative and blocks calcium channels to prevent bone loss.

Trifluridine is a fluorinated thymidine analog with antineoplastic and antiviral properties, disrupting DNA and protein synthesis, leading to apoptosis.

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Pig sC5b-9. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Pig sC5b-9. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Pig sC5b-9, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Pig sC5b-9 in the samples is then determined by comparing the OD of the samples to the standard curve.

<p>Cemiplimab, a human antibody, blocks PD-1 to inhibit T-cell suppression in metastatic and skin cancer studies.</p>

(20S)-Protopanaxadiol (20-Epiprotopanaxadiol) (20-Epiprotopanaxadiol), an apoptosis inducer, is an aglycon metabolic derivative of the protopanaxadiol-type

STL127705 inhibits Ku 70/80 protein & DNA-PKCS kinase, IC50s: 3.5 μM & 2.5 μM.

Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR.

Chlorhexidine is a biguanide antiseptic targeting bacteria, damaging cell membranes and causing cell death, more effective against gram-positive types.

Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis.

Astegolimab (RG 6149) is a humanised IgG2 monoclonal antibody that targets the IL-33 receptor chronic obstructive pulmonary disease (COPD) and severe asthma

Perhexiline maleate is an orally active inhibitor of CPT1 and CPT2 that reduces fatty acid metabolism.

Tiratricol, a thyroid hormone metabolite for hyperlipidemia and obesity, studied in Allan-Herndon-Dudley Syndrome treatment.

Nortriptyline is an antidepressant compound used for smoking cessation.

<p>Pemetrexed disodium treats lung cancer/mesothelioma; may cause moderate serum enzyme elevation, rarely acute liver injury.</p>

Tetrahydropalmatine (DL-Tetrahydropalmatine) is an active component isolated from corydalis, suppressing amygdaloid release of dopamine to inhibit an epileptic

Vincristine sulfate is a natural alkaloid. Vincristine sulfate is used as a microtubule destabilizer for the study of tumors. Cost-effective, quality assurance.

AP20187: Cell-permeable ligand dimerizing FKBP fusion proteins for signaling and gene expression control.

<p>(R)-CR8 ((R)-Isomer) is a potent and selective CDK inhibitor.</p>