Ferroptosi
La ferroptosi è una forma di morte cellulare regolata caratterizzata dall'accumulo di perossidi lipidici e dallo stress ossidativo dipendente dal ferro. A differenza dell'apoptosi, la ferroptosi non è guidata dalle caspasi, ma piuttosto dal fallimento delle difese antiossidanti cellulari, che porta alla morte cellulare. Gli inibitori e gli induttori della ferroptosi sono fondamentali per studiare questa particolare via di morte cellulare, implicata in varie malattie, tra cui il cancro, la neurodegenerazione e il danno da ischemia-riperfusione. Presso CymitQuimica, offriamo una vasta gamma di modulatori della ferroptosi di alta qualità per supportare la tua ricerca sui meccanismi di morte cellulare, stress ossidativo e patologia delle malattie.
Trovati 223 prodotti di "Ferroptosi"
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L-Glutamic Acid
CAS:Formula:C5H9NO4Purezza:>99.0%(T)Colore e forma:White powder to crystalPeso molecolare:147.13Baicalein
CAS:Formula:C15H10O5Purezza:>98.0%(T)Colore e forma:Light yellow to Amber to Dark green powder to crystalPeso molecolare:270.24Ferrostatin-1
CAS:Formula:C15H22N2O2Purezza:>98.0%(HPLC)Colore e forma:White to Amber to Dark purple powder to crystalPeso molecolare:262.35Ebselen
CAS:Formula:C13H9NOSePurezza:>98.0%(GC)Colore e forma:Light orange to Yellow to Green powder to crystalPeso molecolare:274.18Coenzyme Q9
CAS:Formula:C54H82O4Purezza:>98.0%(HPLC)Colore e forma:Light yellow to Yellow to Orange powder to crystalPeso molecolare:795.25Coenzyme Q10
CAS:Formula:C59H90O4Purezza:>98.0%(HPLC)Colore e forma:Light yellow to Yellow to Orange powder to crystalPeso molecolare:863.37Simvastatin
CAS:Formula:C25H38O5Purezza:>97.0%(HPLC)Colore e forma:White to Almost white powder to crystalPeso molecolare:418.576-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic Acid
CAS:Formula:C14H18O4Purezza:>98.0%(GC)(T)Colore e forma:White to Orange to Green powder to crystalinePeso molecolare:250.29Sulfasalazine
CAS:Formula:C18H14N4O5SPurezza:>95.0%(T)(HPLC)Colore e forma:Light yellow to Amber to Dark green powder to crystalPeso molecolare:398.39Erastin
CAS:Formula:C30H31ClN4O4Purezza:>98.0%(HPLC)(qNMR)Colore e forma:White to Light yellow powder to crystalPeso molecolare:547.05Acetylcysteine
CAS:Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent.Formula:C5H9NO3SPurezza:98.01% - >99.99%Colore e forma:Crystals From Water SolidPeso molecolare:163.19Pioglitazone
CAS:Pioglitazone (U 72107) is a selective and oral PPARγ agonist with EC50 of 0.93 and 0.99 μM on human and mouse PPARγ, respectively . High-Quality, Low-Cost!Formula:C19H20N2O3SPurezza:95% - 99.57%Colore e forma:White PowderPeso molecolare:356.44Lapatinib
CAS:Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity.Formula:C29H26ClFN4O4SPurezza:99.00% - 99.81%Colore e forma:PowderPeso molecolare:581.06α-Vitamin E
CAS:α-Vitamin E (Dexrabeprazole Sodium) is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties.Formula:C29H50O2Purezza:98% - 99.89%Colore e forma:Light Yellow LiquidPeso molecolare:430.71Ethylenediaminetetraacetic acid trisodium salt
CAS:Ethylenediaminetetraacetic acid trisodium salt (EDTA Trisodium) used to bind metal ions in the chelation therapy.Formula:C10H13N2Na3O8Purezza:99.92% - 99.96%Colore e forma:White CrystalsPeso molecolare:358.19Artemisinin
CAS:Artemisinin (Qinghaosu) is a natural sesquiterpene lactone. Artemisinin has anti-malarial, neuroprotective and anti-tumor effects. Cost-effective and quality-assured.Formula:C15H22O5Purezza:99.77% - 99.87%Colore e forma:Crystalline SolidPeso molecolare:282.33Artesunate
CAS:Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria.Formula:C19H28O8Purezza:97.67% - 99.9%Colore e forma:White Crystalline PowderPeso molecolare:384.42DL-Glutamine
CAS:DL-Glutamine, a non-essential amino acid, is abundant in the body, aids metabolism, carries nitrogen, and fuels cells.Formula:C5H10N2O3Purezza:99.89%Colore e forma:White Crystalline Powder White Crystalline PowderPeso molecolare:146.14NVS-ZP7-4
CAS:NVS-ZP7-4 is a inhibitor of Zinc transporter SLC39A7 (ZIP7).Formula:C28H28FN5OSPurezza:99.86%Colore e forma:SolidPeso molecolare:501.62Butylhydroxyanisole
CAS:BHA is an antioxidant with two isomers: 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.Formula:C11H16O2Purezza:99.54% - 99.63%Colore e forma:White Solid WaxyPeso molecolare:180.25Vildagliptin
CAS:Vildagliptin (LAF237), an oral DPP-4 inhibitor with hypoglycemic effects, is metabolized and excreted in urine.Formula:C17H25N3O2Purezza:97.81% - >99.99%Colore e forma:White Crystalline PowderPeso molecolare:303.40Lapatinib ditosylate monohydrate
CAS:<p>Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.</p>Formula:C29H26ClFN4O4S·2(C7H8O3S)·H2OPurezza:98% - 99.41%Colore e forma:Colourless To Light-Yellow CrystalPeso molecolare:943.47Gallic acid
CAS:Gallic acid (Benzoic acid) is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.Formula:C7H6O5Purezza:99.38% - 99.57%Colore e forma:White Solid Solid Particulate/PowderPeso molecolare:170.12Pioglitazone hydrochloride
CAS:Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplasticFormula:C19H20N2O3S·HClPurezza:99.64% - >99.99%Colore e forma:White Crystals Or Crystalline PowderPeso molecolare:392.90Sorafenib
CAS:Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57Formula:C21H16ClF3N4O3Purezza:98% - 99.89%Colore e forma:SolidPeso molecolare:464.82Imidazole ketone erastin
CAS:View and buy Imidazole ketone erastin from TargetMol.Imidazole ketone erastin (IKE) is an inducer of ferroptosis. It has inhibition of the system Xc- cystine/glutamate transporter.Cited in 22 publications.Formula:C35H35ClN6O5Purezza:98.48% - 99.87%Colore e forma:SolidPeso molecolare:655.14Butylated hydroxytoluene
CAS:Butylated hydroxytoluene (BHT FCC/NF) is an organic chemical composed of 4-methylphenol modified with tert-butyl groups at positions 2 and 6.Formula:C15H24OPurezza:99.72%Colore e forma:Colourless Solid PowderPeso molecolare:220.35iFSP1
CAS:iFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverseFormula:C20H13N5Purezza:98.74% - 99.74%Colore e forma:SolidPeso molecolare:323.35Dopamine hydrochloride
CAS:Dopamine hydrochloride (ASL279) is a natural catecholamine neurotransmitter, dopamine receptors (D1-5 receptors) (EC50=2.7 nM). High-Quality, Low-Cost!Formula:C8H12ClNO2Purezza:99.47% - 99.72%Colore e forma:SolidPeso molecolare:189.64Deferiprone
CAS:Deferiprone (Deferidone) is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.Formula:C7H9NO2Purezza:99.58% - ≥95%Colore e forma:White NeedlesPeso molecolare:139.15FSEN1
CAS:FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM.Formula:C22H22BrN5OSPurezza:99.54% - 99.97%Colore e forma:SolidPeso molecolare:484.412-(10-hydroxydecyl)-6-methoxy-3-methyl-5-(trideuteriomethoxy)cyclohexa-2,5-diene-1,4-dione
CAS:Formula:C19H30O5Purezza:98%Colore e forma:SolidPeso molecolare:338.4385Pravastatin sodium
CAS:Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.Formula:C23H35NaO7Purezza:97.14% - 99.97%Colore e forma:White Crystalline PowderPeso molecolare:446.52Eugenol
CAS:Eugenol (Allylguaiacol) is a Standardized Chemical Allergen.Formula:C10H12O2Purezza:98.03%Colore e forma:Colorless Or Pale Yellow Liquid Pungent Taste (Ntp 1992)Peso molecolare:164.20Lovastatin
CAS:Lovastatin (MK-803) is an HMG-CoA reductase inhibitor. Lovastatin lowers cholesterol and is used as a lipid-lowering agent. Cost-effective and quality-assured.Formula:C24H36O5Purezza:99.66% - 99.92%Colore e forma:The Substance Is A White-Yellowish To Yellow Powder Solid PowderPeso molecolare:404.54Zileuton
CAS:Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.Formula:C11H12N2O2SPurezza:98.72% - 99.43%Colore e forma:Crystalline SolidPeso molecolare:236.29Simvastatin
CAS:Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity.Formula:C25H38O5Purezza:98.54% - 99.13%Colore e forma:SolidPeso molecolare:418.57Linagliptin
CAS:Linagliptin (BI 1356) is a potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity.Formula:C25H28N8O2Purezza:99.15% - >99.99%Colore e forma:SolidPeso molecolare:472.54Lapatinib Ditosylate
CAS:Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).Formula:C29H26ClFN4O4S·2C7H8O3SPurezza:99.41%Colore e forma:Yellow SolidPeso molecolare:925.46Curcumin
CAS:Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity.Formula:C21H20O6Purezza:95% - 98.98%Colore e forma:Orange-Yellow Crystal Powder; Gives Brownish-Red Color With Alkali; Light-Yellow Color With Acids Physical Description Orange-Yellow Needles (Ntp 1992)Peso molecolare:368.38Ciclopirox
CAS:Ciclopirox is an antifungal that chelates Fe3+ and Al3+, inhibiting enzymes and has antibacterial and anti-inflammatory effects.Formula:C12H17NO2Purezza:97.72% - 99.78%Colore e forma:SolidPeso molecolare:207.27L-Glutathione reduced
CAS:L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals.Formula:C10H17N3O6SPurezza:97.37% - 99.99%Colore e forma:SolidPeso molecolare:307.32Sorafenib tosylate
CAS:<p>Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).</p>Formula:C21H16ClF3N4O3·C7H8O3SPurezza:99.24% - 99.94%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:637.03Sulfasalazine
CAS:Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.Formula:C18H14N4O5SPurezza:98.00% - 99.28%Colore e forma:Minute Brownish-Yellow CrystalsPeso molecolare:398.39Fluvastatin sodium
CAS:Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterolFormula:C24H25FNNaO4Purezza:98.54% - 99.56%Colore e forma:Light Yellow Solid PowderPeso molecolare:433.45Ciclopirox olamine
CAS:<p>Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.</p>Formula:C14H24N2O3Purezza:99.16% - >99.99%Colore e forma:White To Yellow Solid Solid Particulate/PowderPeso molecolare:268.35Cisplatin
CAS:Cisplatin (CDDP) is a DNA cross-linking agent.Formula:Cl2H6N2PtPurezza:97.13% - 99.63%Colore e forma:Orange-Yellow To Deep Yellow Solid Or PowderPeso molecolare:300.04Matrine
CAS:<p>Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.</p>Formula:C15H24N2OPurezza:97.16% - >99.99%Colore e forma:SolidPeso molecolare:248.36Deferasirox
CAS:<p>Deferasirox (CGP-72670) is an oral iron chelating agent used to treat chronic iron overload.</p>Formula:C21H15N3O4Purezza:98.79% - 99.4%Colore e forma:SolidPeso molecolare:373.36Rosiglitazone maleate
CAS:Rosiglitazone maleate (BRL 49653) is an oral antidiabetic and potential anticancer agent.Formula:C22H23N3O7SPurezza:99.33% - 99.51%Colore e forma:Off-White SolidPeso molecolare:473.50
