Ferroptosi
La ferroptosi è una forma di morte cellulare regolata caratterizzata dall'accumulo di perossidi lipidici e dallo stress ossidativo dipendente dal ferro. A differenza dell'apoptosi, la ferroptosi non è guidata dalle caspasi, ma piuttosto dal fallimento delle difese antiossidanti cellulari, che porta alla morte cellulare. Gli inibitori e gli induttori della ferroptosi sono fondamentali per studiare questa particolare via di morte cellulare, implicata in varie malattie, tra cui il cancro, la neurodegenerazione e il danno da ischemia-riperfusione. Presso CymitQuimica, offriamo una vasta gamma di modulatori della ferroptosi di alta qualità per supportare la tua ricerca sui meccanismi di morte cellulare, stress ossidativo e patologia delle malattie.
Trovati 223 prodotti di "Ferroptosi"
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6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic Acid
CAS:Formula:C14H18O4Purezza:>98.0%(GC)(T)Colore e forma:White to Orange to Green powder to crystalinePeso molecolare:250.29Erastin
CAS:Formula:C30H31ClN4O4Purezza:>98.0%(HPLC)(qNMR)Colore e forma:White to Light yellow powder to crystalPeso molecolare:547.05Ferrostatin-1
CAS:Formula:C15H22N2O2Purezza:>98.0%(HPLC)Colore e forma:White to Amber to Dark purple powder to crystalPeso molecolare:262.35Coenzyme Q9
CAS:Formula:C54H82O4Purezza:>98.0%(HPLC)Colore e forma:Light yellow to Yellow to Orange powder to crystalPeso molecolare:795.25Simvastatin
CAS:Formula:C25H38O5Purezza:>97.0%(HPLC)Colore e forma:White to Almost white powder to crystalPeso molecolare:418.57L-Glutamic Acid
CAS:Formula:C5H9NO4Purezza:>99.0%(T)Colore e forma:White powder to crystalPeso molecolare:147.13Ebselen
CAS:Formula:C13H9NOSePurezza:>98.0%(GC)Colore e forma:Light orange to Yellow to Green powder to crystalPeso molecolare:274.18Baicalein
CAS:Formula:C15H10O5Purezza:>98.0%(T)Colore e forma:Light yellow to Amber to Dark green powder to crystalPeso molecolare:270.24Sulfasalazine
CAS:Formula:C18H14N4O5SPurezza:>95.0%(T)(HPLC)Colore e forma:Light yellow to Amber to Dark green powder to crystalPeso molecolare:398.39Coenzyme Q10
CAS:Formula:C59H90O4Purezza:>98.0%(HPLC)Colore e forma:Light yellow to Yellow to Orange powder to crystalPeso molecolare:863.37Matrine
CAS:<p>Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.</p>Formula:C15H24N2OPurezza:97.16% - >99.99%Colore e forma:SolidPeso molecolare:248.366-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid
CAS:Formula:C14H18O4Purezza:98%Colore e forma:SolidPeso molecolare:250.2903Ref: IN-DA003N8E
1g30,00€5g66,00€10g114,00€1kgPrezzo su richiesta25g159,00€50g284,00€100g526,00€500gPrezzo su richiesta100mg21,00€250mg25,00€iFSP1
CAS:iFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverseFormula:C20H13N5Purezza:98.74% - 99.74%Colore e forma:SolidPeso molecolare:323.35Cisplatin
CAS:Cisplatin (CDDP) is a DNA cross-linking agent.Formula:Cl2H6N2PtPurezza:97.13% - 99.63%Colore e forma:Orange-Yellow To Deep Yellow Solid Or PowderPeso molecolare:300.04Gallic acid
CAS:Gallic acid (Benzoic acid) is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.Formula:C7H6O5Purezza:99.38% - 99.57%Colore e forma:White Solid Solid Particulate/PowderPeso molecolare:170.12Lovastatin
CAS:Lovastatin (MK-803) is an HMG-CoA reductase inhibitor. Lovastatin lowers cholesterol and is used as a lipid-lowering agent. Cost-effective and quality-assured.Formula:C24H36O5Purezza:99.66% - 99.92%Colore e forma:The Substance Is A White-Yellowish To Yellow Powder Solid PowderPeso molecolare:404.54Lapatinib ditosylate monohydrate
CAS:<p>Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.</p>Formula:C29H26ClFN4O4S·2(C7H8O3S)·H2OPurezza:98% - 99.41%Colore e forma:Colourless To Light-Yellow CrystalPeso molecolare:943.47Eugenol
CAS:Eugenol (Allylguaiacol) is a Standardized Chemical Allergen.Formula:C10H12O2Purezza:98.03%Colore e forma:Colorless Or Pale Yellow Liquid Pungent Taste (Ntp 1992)Peso molecolare:164.20DL-Glutamine
CAS:DL-Glutamine, a non-essential amino acid, is abundant in the body, aids metabolism, carries nitrogen, and fuels cells.Formula:C5H10N2O3Purezza:99.89%Colore e forma:White Crystalline Powder White Crystalline PowderPeso molecolare:146.14Dopamine hydrochloride
CAS:Dopamine hydrochloride (ASL279) is a natural catecholamine neurotransmitter, dopamine receptors (D1-5 receptors) (EC50=2.7 nM). High-Quality, Low-Cost!Formula:C8H12ClNO2Purezza:99.47% - 99.72%Colore e forma:SolidPeso molecolare:189.64(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
CAS:Formula:C25H38O5Purezza:98%Colore e forma:SolidPeso molecolare:418.5662L-Glutamine
CAS:L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present in the human body and involved in many metabolic processes. High-Quality, Low-Cost!Formula:C5H10N2O3Purezza:99.66% - 99.98%Colore e forma:Solid CrystallinePeso molecolare:146.14Vildagliptin
CAS:Vildagliptin (LAF237), an oral DPP-4 inhibitor with hypoglycemic effects, is metabolized and excreted in urine.Formula:C17H25N3O2Purezza:97.81% - >99.99%Colore e forma:White Crystalline PowderPeso molecolare:303.40Sorafenib
CAS:Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57Formula:C21H16ClF3N4O3Purezza:98% - 99.89%Colore e forma:SolidPeso molecolare:464.82Deferasirox
CAS:<p>Deferasirox (CGP-72670) is an oral iron chelating agent used to treat chronic iron overload.</p>Formula:C21H15N3O4Purezza:98.79% - 99.4%Colore e forma:SolidPeso molecolare:373.36Baicalein
CAS:Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor.Formula:C15H10O5Purezza:97.06% - 98.48%Colore e forma:Yellow Crystalline SolidPeso molecolare:270.24Pioglitazone
CAS:Pioglitazone (U 72107) is a selective and oral PPARγ agonist with EC50 of 0.93 and 0.99 μM on human and mouse PPARγ, respectively . High-Quality, Low-Cost!Formula:C19H20N2O3SPurezza:95% - 99.57%Colore e forma:White PowderPeso molecolare:356.44Rosiglitazone maleate
CAS:Rosiglitazone maleate (BRL 49653) is an oral antidiabetic and potential anticancer agent.Formula:C22H23N3O7SPurezza:99.33% - 99.51%Colore e forma:Off-White SolidPeso molecolare:473.50Imidazole ketone erastin
CAS:View and buy Imidazole ketone erastin from TargetMol.Imidazole ketone erastin (IKE) is an inducer of ferroptosis. It has inhibition of the system Xc- cystine/glutamate transporter.Cited in 22 publications.Formula:C35H35ClN6O5Purezza:98.48% - 99.87%Colore e forma:SolidPeso molecolare:655.14Acetylcysteine
CAS:Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent.Formula:C5H9NO3SPurezza:98.01% - >99.99%Colore e forma:Crystals From Water SolidPeso molecolare:163.19α-Vitamin E
CAS:α-Vitamin E (Dexrabeprazole Sodium) is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties.Formula:C29H50O2Purezza:98% - 99.89%Colore e forma:Light Yellow LiquidPeso molecolare:430.71Fluvastatin sodium
CAS:Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterolFormula:C24H25FNNaO4Purezza:98.54% - 99.56%Colore e forma:Light Yellow Solid PowderPeso molecolare:433.45Deferiprone
CAS:Deferiprone (Deferidone) is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.Formula:C7H9NO2Purezza:99.58% - ≥95%Colore e forma:White NeedlesPeso molecolare:139.15Butylated hydroxytoluene
CAS:Butylated hydroxytoluene (BHT FCC/NF) is an organic chemical composed of 4-methylphenol modified with tert-butyl groups at positions 2 and 6.Formula:C15H24OPurezza:99.72%Colore e forma:Colourless Solid PowderPeso molecolare:220.35Lapatinib
CAS:Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity.Formula:C29H26ClFN4O4SPurezza:99.00% - 99.81%Colore e forma:PowderPeso molecolare:581.06Artesunate
CAS:Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria.Formula:C19H28O8Purezza:97.67% - 99.9%Colore e forma:White Crystalline PowderPeso molecolare:384.42NVS-ZP7-4
CAS:NVS-ZP7-4 is a inhibitor of Zinc transporter SLC39A7 (ZIP7).Formula:C28H28FN5OSPurezza:99.86%Colore e forma:SolidPeso molecolare:501.62Ciclopirox olamine
CAS:<p>Ciclopirox olamine is a broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities.</p>Formula:C14H24N2O3Purezza:99.16% - >99.99%Colore e forma:White To Yellow Solid Solid Particulate/PowderPeso molecolare:268.35Ethylenediaminetetraacetic acid trisodium salt
CAS:Ethylenediaminetetraacetic acid trisodium salt (EDTA Trisodium) used to bind metal ions in the chelation therapy.Formula:C10H13N2Na3O8Purezza:99.92% - 99.96%Colore e forma:White CrystalsPeso molecolare:358.19Ref: IN-DA00396N
1g24,00€5g40,00€1kgPrezzo su richiesta25g99,00€2kgPrezzo su richiesta50g141,00€5kgPrezzo su richiesta100g196,00€Lapatinib Ditosylate
CAS:Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).Formula:C29H26ClFN4O4S·2C7H8O3SPurezza:99.41%Colore e forma:Yellow SolidPeso molecolare:925.46Curcumin
CAS:Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity.Formula:C21H20O6Purezza:95% - 98.98%Colore e forma:Orange-Yellow Crystal Powder; Gives Brownish-Red Color With Alkali; Light-Yellow Color With Acids Physical Description Orange-Yellow Needles (Ntp 1992)Peso molecolare:368.38Simvastatin
CAS:Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity.Formula:C25H38O5Purezza:98.54% - 99.13%Colore e forma:SolidPeso molecolare:418.57FSEN1
CAS:FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM.Formula:C22H22BrN5OSPurezza:99.54% - 99.97%Colore e forma:SolidPeso molecolare:484.412-(10-hydroxydecyl)-6-methoxy-3-methyl-5-(trideuteriomethoxy)cyclohexa-2,5-diene-1,4-dione
CAS:Formula:C19H30O5Purezza:98%Colore e forma:SolidPeso molecolare:338.4385Sulfasalazine
CAS:Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.Formula:C18H14N4O5SPurezza:98.00% - 99.28%Colore e forma:Minute Brownish-Yellow CrystalsPeso molecolare:398.39Ciclopirox
CAS:Ciclopirox is an antifungal that chelates Fe3+ and Al3+, inhibiting enzymes and has antibacterial and anti-inflammatory effects.Formula:C12H17NO2Purezza:97.72% - 99.78%Colore e forma:SolidPeso molecolare:207.27Artemisinin
CAS:Artemisinin (Qinghaosu) is a natural sesquiterpene lactone. Artemisinin has anti-malarial, neuroprotective and anti-tumor effects. Cost-effective and quality-assured.Formula:C15H22O5Purezza:99.77% - 99.87%Colore e forma:Crystalline SolidPeso molecolare:282.33Roxadustat
CAS:Roxadustat (FG-4592) is an orally bioavailable, hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), with potential anti-anemic activity.Formula:C19H16N2O5Purezza:99% - 99.88%Colore e forma:SolidPeso molecolare:352.34L-Glutathione reduced
CAS:L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals.Formula:C10H17N3O6SPurezza:97.37% - 99.99%Colore e forma:SolidPeso molecolare:307.32Pravastatin sodium
CAS:Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.Formula:C23H35NaO7Purezza:97.14% - 99.97%Colore e forma:White Crystalline PowderPeso molecolare:446.52Linagliptin
CAS:Linagliptin (BI 1356) is a potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity.Formula:C25H28N8O2Purezza:99.15% - >99.99%Colore e forma:SolidPeso molecolare:472.54Sorafenib tosylate
CAS:<p>Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).</p>Formula:C21H16ClF3N4O3·C7H8O3SPurezza:99.24% - 99.94%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:637.03Pioglitazone hydrochloride
CAS:Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplasticFormula:C19H20N2O3S·HClPurezza:99.64% - >99.99%Colore e forma:White Crystals Or Crystalline PowderPeso molecolare:392.90Butylhydroxyanisole
CAS:BHA is an antioxidant with two isomers: 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.Formula:C11H16O2Purezza:99.54% - 99.63%Colore e forma:White Solid WaxyPeso molecolare:180.25Zileuton
CAS:Zileuton (A 64077) inhibits 5-lipoxygenase, reduces leukotrienes, aids bronchodilation, lessens mucus/edema, and helps manage asthma symptoms.Formula:C11H12N2O2SPurezza:98.72% - 99.43%Colore e forma:Crystalline SolidPeso molecolare:236.29Ferroptosis-IN-3
Ferroptosis-IN-3 (Compound 25), a ferroptosis inhibitor, demonstrates potent activity by inhibiting RSL3-induced ferroptosis in HT-1080 cells (EC50: 8.6 nM).Purezza:98%Colore e forma:Odour SolidFerroptosis inducer-4
Ferroptosisinducer-4 (Compound 5) is a phospholipid-based ferroptosis inducer featuring a terminal double bond at the sn-2 position. It exhibits significant cytotoxicity towards HT-1080 cells with an IC50 value of 18 μM. The toxicity mechanism involves the generation of lipid peroxides and oxidative damage to the cell membrane induced by the terminal double bond. Ferroptosisinducer-4 can be utilized in studies pertaining to the regulation of ferroptosis.Formula:C33H64NO7PColore e forma:SolidPeso molecolare:617.84PROTAC GPX4 degrader-4
CAS:PROTACGPX4 degrader-4 is a GPX4 PROTAC degrader with a DC50 of 5.32 nM. It inhibits the activity of cancer cell lines RT4, T24, and J82 with IC50 values of 0.09, 2.97, and 7.58 μM, respectively. This compound elevates lipid ROS levels and induces ferroptosis in T24 and RT4 cells. In T24 tumor-bearing BALB/c nude mouse models, PROTACGPX4 degrader-4 demonstrates antitumor activity. It is applicable to bladder cancer research.Formula:C43H58N2O13Colore e forma:SolidPeso molecolare:810.93Photosensitizer-5
Photosensitizer-5, a photodynamic agent, exhibits cytotoxicity towards HeLa and HepG2 cells, with IC50 values of 10.4 nM and 6.9 nM, respectively. It induces cell death through lipid peroxidation via an iron-independent ferroptosis pathway. Additionally, Photosensitizer-5 displays antitumor activity in HeLa-tumor-bearing mice.Formula:C35H26BF2IN4O2Colore e forma:SolidPeso molecolare:710.32Ru-Poma
<p>Ru-Poma is an Ru(II)-based photosensitizer designed to enhance the efficacy of photodynamic therapy (PDT) against tumors resistant to Cisplatin. It targets Pomalidomide to partially degrade CRBN, inducing ferroptosis by increasing lipid peroxides and downregulating GPX4 and GAPDH expression. In A549 cells, Ru-Poma exhibits cytotoxicity with IC50 values of 18.46 μM in the dark and 0.37 μM under illumination.</p>Formula:C89H75Cl2N11O11Ru·7H2OPROTAC GPX4 degrader-2
PROTACGPX4 degrader-2 (compound 18a) is a proteolysis-targeting chimera (PROTAC) that targets the degradation of glutathione peroxidase 4 (GPX4), with a DC50, 48h value of 1.68 μM. It induces the accumulation of lipid peroxides and mitochondrial depolarization, subsequently triggering ferroptosis. Additionally, PROTACGPX4 degrader-2 exhibits antiproliferative activity.Formula:C50H61ClN8O9Peso molecolare:952.425Anticancer agent 178
<p>Anticanceragent 178 (compound C2) is a potent anticancer compound. It effectively inhibits the proliferation and metabolic activity of MDA-MB 231 cells, with IC50 values of 1.1 and 4.2 μM, respectively. Additionally, Anticanceragent 178 induces ferroptosis and necroptosis in cells.</p>Formula:C32H30ClFeN2O6Peso molecolare:629.11418Pro-GA
CAS:Pro-GA is a cell-permeable γ-glutamylcyclotransferase (γ-GGCT) inhibitor that inhibit proliferation in multiple bladder cancer cell lines. antitumour.Formula:C12H19NO7Colore e forma:SolidPeso molecolare:289.28ZX782
ZX782 acts as a GPX4 protein degrader and an inducer of ferroptosis (Ferroptosis), targeting GPX4 for destruction via both the ubiquitin-proteasome system and the autophagy-lysosome pathway. Following the degradation of GPX4 induced by ZX782, there is a significant increase in the accumulation of lipid reactive oxygen species (ROS) in HT1080 cells.Formula:C39H48ClN5O8Colore e forma:SolidPeso molecolare:750.281-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE
CAS:<p>Phospholipid with stearic acid and 15(S)-HpETE boosts ferroptosis in MEFs upon GPX4 inhibition.</p>Formula:C43H78NO10PColore e forma:SolidPeso molecolare:800.068TOFA-Plasmalogen
<p>TOFA-Plasmalogen (compound 1), a derivative of glyceraldehyde, exhibits ferroptosis-inducing properties. This compound promotes lipid peroxidation in cell membranes, leading to cytotoxic effects with an inhibition concentration (IC 50 = 32.87 μM).</p>Formula:C33H62NO7PColore e forma:SolidPeso molecolare:615.82W1131 TFA
W1131 TFA is a STAT3 inhibitor and ferroptosis inducer that regulates the IL6-JAK-STAT3 and ferroptosis pathways,gastric cancer.Formula:C25H20F3N5O6Purezza:98.1%Colore e forma:SolidPeso molecolare:543.45Ferroptosis-IN-14
Ferroptosis-IN-14 (compund 36) exhibits the most potent anti-ferroptotic activity with an EC50 value of 0.58 ± 0.02 μM, demonstrating excellent anti-ferroptotic efficacy, as well as stability in microsomes and plasma.Colore e forma:Odour SolidDTUN
<p>DTUN: lipophilic radical initiator, starts STY-BODIPY liposome co-autoxidization at 0.2 mM, useful in FENIX assays.</p>Colore e forma:Solid2-Acetamidophenol
CAS:<p>2-Acetamidophenol (Orthocetamol) has analgesic and antipyretic effects. 2-Acetamidophenol is an isomer of Paracetamol (4-acetamidophenol).</p>Formula:C8H9NO2Purezza:>99.99%Colore e forma:Light Brown PowderPeso molecolare:151.16GPX4-IN-14
GPX4-IN-14 (compound 2c) acts as a GPX4 inhibitor, exhibiting both free radical scavenging activity (with a maximum scavenging rate of 72.52%) and anti-tumor proliferation activity in vitro. This compound targets GPX4 protein, elevating lipid peroxide and intracellular Reactive Oxygen Species (ROS) levels, which induces ferroptosis and contributes to its anti-tumor proliferation effects.Formula:C26H39NO8SeColore e forma:SolidPeso molecolare:572.55HDAC-IN-77
HDAC-IN-77 (HL-5s), an HDAC inhibitor, has the capability to induce ferroptosis and suppress the Nrf2/HO-1 signaling pathway. This compound is utilized in cancer research.Formula:C22H26N4O2SColore e forma:SolidPeso molecolare:410.531R,3R-RSL3
CAS:1R,3R-RSL3 is a negative control for1S, 3R-RSL3.Formula:C23H21ClN2O5Colore e forma:SolidPeso molecolare:440.88Ferroptosis-IN-20
Ferroptosis-IN-20 (Compound 34a) is an inhibitor of ferroptosis targeting voltage-dependent anion channels (VDAC) with an EC50 of 24.2 nM. It prevents VDAC oligomerization and lipid peroxidation. Additionally, Ferroptosis-IN-20 reduces ROS levels, diminishes TFR1-mediated iron uptake, inhibits Fe2+ levels, and restores glutathione (GSH) levels. It also alleviates acute kidney injury (AKI) caused by folic acid.Colore e forma:Odour SolidAY-4
AY-4 (Compound AY-4) is a potent PROTAC degrader targeting FTH1, with a dissociation constant (Kd) of 3.17 nM. It effectively increases intracellular ferrous (Fe2+) and ferric (Fe3+) ion levels. AY-4 is a potential anticancer candidate that regulates iron homeostasis through ferritin degradation, enhancing the efficacy of existing drugs. Additionally, AY-4 significantly reduces FTH1 levels in breast cancer cells.Colore e forma:Odour SolidZX703
ZX703 is a protein hydrolysis-targeting chimera (PROTAC) that mediates the degradation of GPX4 through the ubiquitin-proteasome and autophagy-lysosome pathways, with a DC50 of 0.315 µM. It induces the accumulation of lipid reactive oxygen species (ROS), thereby promoting ferroptosis in cancer cells.Chlorido[N,N'-disalicylidene-1,2-phenylenediamine]iron(III)
CAS:Iron(III) compound induces ferroptosis in NB1 cells at 3μM, not apoptosis/necroptosis; inhibits various cancers, effective against drug-resistant NALM-6.Formula:C20H14ClFeN2O2Colore e forma:SolidPeso molecolare:405.64CQ-ER
<p>CQ-ER is a Coumarin-quinazolinone-based photosensitizer targeting the endoplasmic reticulum (ER). It induces ferroptosis, thereby enhancing photodynamic therapy (PDT).</p>Formula:C33H33N7O6SColore e forma:SolidPeso molecolare:655.72Ferroptosis-IN-16
<p>Ferroptosis-IN-16 (Compound 13l) acts as a specific inhibitor of ferroptosis, demonstrating EC50 values of 0.7 nM in ES-2 cells and 0.9 nM in LX-2 cells. It effectively alleviates acute liver injury induced by Acetaminophen in mouse models and shows excellent metabolic stability in mouse liver microsomes.</p>Formula:C26H23N5OColore e forma:SolidPeso molecolare:421.49Ferroptosis Compound Library
<p>A unique collection of 779 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study；</p>Colore e forma:Odour SolidGDCNF-11
CAS:<p>GDCNF-11, an HSP90-based HIM-PROTACGPX4 degrader, facilitates the ubiquitination and degradation of GPX4 through the HSP90 chaperone complex. This reduction in endogenous GPX4 induces ferroptosis in HT-1080 cells, with a DC50 value of 0.08 μM.</p>Formula:C48H53Cl2N13O5SColore e forma:SolidPeso molecolare:994.99Ferroptosis inducer-6
CAS:Ferroptosisinducer 6 (6d) is an inducer of ferroptosis (ferroptosis) that exhibits potent potential for Type I/II photodynamic therapy by inducing ROS production, oxidative stress, and mitochondrial damage. Additionally, it demonstrates antitumor activity.Formula:C69H78F12N12P2RuColore e forma:SolidPeso molecolare:1466.44NC-R17
NC-R17, an RSL3-based noncovalent GPX4 degrader implicated in ferroptosis, demonstrates anti-tumor activity and is utilized in the design of noncovalent GPX4-Formula:C53H67N7O7Purezza:98%Colore e forma:SolidPeso molecolare:914.14Ferroptosis-IN-12
Ferroptosis-IN-12 (Cpd-A1) is an inhibitor of ferroptosis. It effectively suppresses ferroptosis in mouse renal tubular epithelial cells (mTECs) treated with Erastin and improves renal function in dose-dependent manners in mouse models of acute kidney injury (AKI) induced by ischemia/reperfusion (I/R) or cecal ligation and puncture (CLP). This compound also reduces renal tubular damage and eliminates inflammation. Exhibiting good plasma stability and high distribution in renal tissues during pharmacokinetic studies in mice, Ferroptosis-IN-12 shows promising potential for research in the field of AKI.Colore e forma:Odour SolidFerroptosis-IN-1
Ferroptosis-IN-1, a diterpene derived from A.Formula:C22H34O5Purezza:98%Colore e forma:SolidPeso molecolare:378.5NA-Ir
CAS:<p>NA-Ir is a ferroptosis (Ferroptosis) inducer that targets mitochondrial DNA (mtDNA) and activates the cGAS-STING pathway to stimulate ferritin autophagy (). It also induces the production of reactive oxygen species (ROS) through photodynamic therapy (PDT), depletes glutathione (GSH), and downregulates glutathione peroxidase 4 (GPX4), thereby triggering lipid peroxidation and ferroptosis. NA-Ir exhibits enhanced anticancer activity under light exposure and selectively inhibits cancer cells with high H2S content.</p>Formula:C49H36F6IrN8O4PColore e forma:SolidPeso molecolare:1138.04GPX4-IN-7
<p>GPX4-IN-7 (Compound 31), an indirubin derivative, serves as a ferroptosis inducer in colon cancer treatment.</p>Formula:C25H23ClN4O4Purezza:98%Colore e forma:SolidPeso molecolare:478.93VEGFR-2-IN-68
<p>VEGFR-2-IN-68 (13b) is an inhibitor of VEGFR-2 with an IC50 value of 41.51 nM. It can induce apoptosis and cause G2/M cell cycle arrest, as well as exhibit anti-cancer metastasis properties.</p>Formula:C27H25N5O2SColore e forma:SolidPeso molecolare:483.1729Ferroptosis-IN-17
Ferroptosis-IN-17 (Compound 18) is an inhibitor of ferroptosis with an EC50 value of 0.57 μM. It effectively reduces the accumulation of intracellular ferrous ions and lipid peroxidation while restoring levels of glutathione (GSH) and glutathione peroxidase 4 (GPX4). In rat plasma, Ferroptosis-IN-17 demonstrates good solubility and notable metabolic stability. This compound holds potential for research in tumor suppression, neurodegenerative diseases, and cardiovascular disorders.Formula:C21H26N4O5SColore e forma:SolidPeso molecolare:446.52UAMC-4821
UAMC-4821 is a ferroptosis inhibitor with an IC50 of 5.2 nM. It effectively scavenges free radicals, inhibits lipid peroxidation, and prevents ML162-induced ferroptosis, providing protective effects on HT-1080 cells. With favorable pharmacokinetic properties in mice, UAMC-4821 presents an oral bioavailability of 63% and demonstrates blood-brain barrier permeability.Formula:C15H19N3OColore e forma:SolidPeso molecolare:257.33NYY-6a
NYY-6a is a ferroptosis (Ferroptosis) inhibitor, demonstrating significant suppression of RSL3-induced ferroptosis in 786-O and HT-1080 cells, with EC50 values of 52 nM and 50 nM, respectively. As a radical-trapping antioxidant (RTA), NYY-6a effectively reduces lipid peroxidation, comparable to ferrostatin-1 and liproxstatin-1, making it useful for research into ferroptosis-related pathologies.Formula:C23H22N2O3Colore e forma:SolidPeso molecolare:374.43GPX4-IN-5
CAS:GPX4-IN-5 is a GPX4 inhibitor with antitumor activity.GPX4-IN-5 induces iron death and may be used for the treatment of triple negative breast cancer.Formula:C18H17ClFNO5Purezza:99.58%Colore e forma:SoildPeso molecolare:381.78PRLX-93936 HCL
CAS:PRLX-93936 HCL is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin.Formula:C21H26Cl2N4O2Purezza:98.4% - 99.94%Colore e forma:SolidPeso molecolare:437.37Ferroptosis-IN-13
Ferroptosis-IN-13 (compound NY-26) is an inhibitor of ferroptosis. It effectively suppresses RSL3-induced ferroptosis in 786-O cells, with an EC50 value of 62 nM.Formula:C32H30F2N4O3Colore e forma:SolidPeso molecolare:556.602GPX4-IN-6
CAS:GPX4-IN-6 is a GPX4 inhibitor with antitumor activity.GPX4-IN-6 induces iron death and is used for the treatment and prevention of triple-negative breast cancerFormula:C18H17BrFNO5Purezza:99.54%Colore e forma:SoildPeso molecolare:426.2384-B10
CAS:84-B10 provides protection in cisplatin-induced acute kidney injury, reversing lipid peroxidation accumulation and downregulation of key ferroptosis inhibitors.Formula:C25H22F3NO5Purezza:99.76%Colore e forma:SolidPeso molecolare:473.44VK-28
CAS:VK-28 is a brain permeable iron chelator with neuroprotection. VK-28 inhibits basal as well as iron-induced mitochondrial lipid peroxidation.Formula:C16H21N3O2Purezza:99.87%Colore e forma:SolidPeso molecolare:287.36PROTAC GPX4 degrader-1
CAS:PROTAC GPX4 Degrader-1 (DC-2) is a PROTAC-based compound that efficiently degrades GPX4, demonstrating a degradation concentration (DC 50) of 0.03 μM in HT1080Formula:C50H57ClN10O10Colore e forma:SolidPeso molecolare:993.5Moracin N
CAS:Moracin N, a ferroptosis inhibitor derived from mulberry leaves, exhibits neuroprotective activity by mitigating oxidative stress [1].Formula:C19H18O4Purezza:98%Colore e forma:SolidPeso molecolare:310.34Chalcones A-N-5
CAS:Chalcones A-N-5, a non-cytotoxic trihydroxy chalcone, aids cell growth & neuroprotection, inhibits ferroptosis, and targets AD research.Formula:C21H20N4O4Colore e forma:SolidPeso molecolare:392.41Fluorescein-diisobutyrate-6-amide
CAS:Fluorescein-diisobutyrate-6-amide, a powerful inducer of ferroptosis, shows promise for cancer research applications [1].Formula:C62H61ClN6O16Colore e forma:SolidPeso molecolare:1181.63Ferumoxytol
CAS:Ferumoxytol is an iron oxide nanoparticle with anti-leukemia properties, specifically against acute myeloid leukemia (AML) cells with low ferroportin (FPN) expression. By increasing intracellular iron levels, Ferumoxytol induces the Fenton reaction to produce reactive oxygen species (ROS), resulting in oxidative stress and ferroptosis. It selectively kills leukemia cells with low FPN expression while sparing normal cells, making it useful for studying leukemia targeting iron metabolism abnormalities.Colore e forma:SolidPROTAC NCOA4 degrader-1
PROTACNCOA4 degrader-1 (Compound V3) is a PROTAC-based degrader of NCOA4, exhibiting a DC50 of 3 nM in HeLa cells. Besides acting as a ferroptosis inhibitor, this compound effectively reduces the levels of NCOA4 and decreases intracellular ferrous (Fe2+) levels. Moreover, PROTACNCOA4 degrader-1 ameliorates liver damage in a CCl4-induced acute liver injury model.Colore e forma:Odour SolidIdebenone
CAS:Formula:C19H30O5Purezza:>98.0%(T)(HPLC)Colore e forma:Light yellow to Brown powder to crystalPeso molecolare:338.44CCW16
CAS:CCW16 is a covalent E3 ubiquitin ligase RNF4 ligand, cysteine reactivity, inducing ferroptosis in AML cells by activating ROS signalling.Formula:C22H20ClNO3Purezza:97%Colore e forma:SolidPeso molecolare:381.85CuATSM
CAS:Cu/Zn-SOD1 enzyme scavenges radicals; mutations cause ALS. Cu-ATSM, crossing blood-brain barrier, targets hypoxic tissue, may aid ALS mice.Formula:C8H14CuN6S2Colore e forma:SolidPeso molecolare:321.92Cerivastatin sodium
CAS:Cerivastatin sodium (BAY W 6228 sodium) is an HMG-CoA reductase inhibitor with lipid-lowering activity that reduces LDL cholesterol levels.Formula:C26H33FNNaO5Purezza:98.50% - 99.67%Colore e forma:SolidPeso molecolare:481.53CuATSP
CAS:CuATSP is a potent free radical trapping antioxidant (RTA) and ferroptosis inhibitor inhibit lipid peroxidation, for (ALS) and Parkinson's disease.Formula:C18H18CuN6S2Purezza:97.09%Colore e forma:SolidPeso molecolare:446.05Liproxstatin-1
CAS:Liproxstatin-1 is a potent and selective inhibitor of iron death (IC50=22 nM).Formula:C19H21ClN4Purezza:97.11% - 99.44%Colore e forma:SolidPeso molecolare:340.85L-Glutamic acid monosodium salt
CAS:<p>L-Glutamic acid monosodium salt (MSG) (Monosodium glutamate) is an activator of mGlu1 receptor.</p>Formula:C5H8NO4·NaPurezza:99.93%Colore e forma:White Solid CrystallinePeso molecolare:169.11Piperlongumine
CAS:Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L.Formula:C17H19NO5Purezza:97.03% - 99.90%Colore e forma:SolidPeso molecolare:317.34NADPH tetracyclohexanamine
CAS:<p>NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.</p>Formula:C45H82N11O17P3Purezza:98.73% - 99.05%Colore e forma:SolidPeso molecolare:1142.12L-BUTHIONINE-(S,R)-SULFOXIMINE
CAS:L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase that induces oxidative stress by depleting GSH.Formula:C8H18N2O3SPurezza:97.07% - ≥98%Colore e forma:White Fine PowderPeso molecolare:222.31ML-210
CAS:<p>ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor. ML-210 has antitumor activity and induces ferroptosis. Cost-effective and quality-assured.</p>Formula:C22H20Cl2N4O4Purezza:97% - 99.03%Colore e forma:SolidPeso molecolare:475.32Piperazine Erastin
CAS:<p>Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.</p>Formula:C35H41ClN6O4Purezza:99.52%Colore e forma:SolidPeso molecolare:645.19RSL3
CAS:<p>View and buy RSL3 from TargetMol.RSL3 is a VDAC-independent ferroptosis activator.Cited in 10 publications.</p>Formula:C23H21ClN2O5Purezza:98% - 99.96%Colore e forma:SolidPeso molecolare:440.88TBHQ
CAS:TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.Formula:C10H14O2Purezza:99.17% - 99.53%Colore e forma:White Solid PowderPeso molecolare:166.22Trolox
CAS:Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.Formula:C14H18O4Purezza:98.90% - 99.90%Colore e forma:White To Fainly Beige Crystalline PowderPeso molecolare:250.29Alogliptin
CAS:Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9Formula:C18H21N5O2Purezza:99.63%Colore e forma:SolidPeso molecolare:339.39Alogliptin Benzoate
CAS:Alogliptin Benzoate, a potent DPP-4 inhibitor with >10,000-fold selectivity over DPP-8/9, may also curb TLR-4-induced inflammation.Formula:C25H27N5O4Purezza:99.94% - >99.99%Colore e forma:White PowderPeso molecolare:461.51WITHAFERIN A
CAS:WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/Formula:C28H38O6Purezza:97.41% - 99.99%Colore e forma:SolidPeso molecolare:470.60Bardoxolone Methyl
CAS:Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-Formula:C32H43NO4Purezza:97.81% - 99.09%Colore e forma:SolidPeso molecolare:505.69Siramesine hydrochloride
CAS:Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibitFormula:C30H32ClFN2OPurezza:99.72% - >99.99%Colore e forma:SolidPeso molecolare:491.04Necrostatin-1
CAS:Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.Formula:C13H13N3OSPurezza:99.25% - >99.99%Colore e forma:SolidPeso molecolare:259.33JKE-1674
CAS:JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.Formula:C20H20Cl2N4O4Purezza:98.02% - 98.4%Colore e forma:SolidPeso molecolare:451.3Bay 11-7085
CAS:Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).Formula:C13H15NO2SPurezza:99.76% - 99.94%Colore e forma:White SolidPeso molecolare:249.33DL-Buthionine-(S,R)-sulfoximine
CAS:DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.Formula:C8H18N2O3SPurezza:98% - 99.64%Colore e forma:White Fine PowderPeso molecolare:222.31Coenzyme Q10
CAS:Coenzyme Q10 (CoQ10) (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain.Formula:C59H90O4Purezza:99.14% - 99.88%Colore e forma:DrypowderPeso molecolare:863.34ML162
CAS:ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptosis. ML162 has antitumor activity. Cost-effective and quality-assured.Formula:C23H22Cl2N2O3SPurezza:98.42% - 99.55%Colore e forma:SolidPeso molecolare:477.4(E)-Ferulic acid
CAS:(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression ofFormula:C10H10O4Purezza:99.63%Colore e forma:SolidPeso molecolare:194.18D-glutamine
CAS:D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.Formula:C5H10N2O3Purezza:99.99%Colore e forma:White Or Off-White PowderPeso molecolare:146.14BAY 87-2243
CAS:BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1).Formula:C26H26F3N7O2Purezza:98% - 99.95%Colore e forma:SolidPeso molecolare:525.53L-Buthionine-(S,R)-sulfoximine hydrochloride
L-Buthionine-(S,R)-sulfoximine hydrochloride is a fast, irreversible γ-GCS inhibitor that depletes glutathione. IC50: 1.9-29 μM in various tumors.Formula:C8H19ClN2O3SColore e forma:SolidPeso molecolare:258.77Liproxstatin-1 hydrochloride
CAS:Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].Formula:C19H22Cl2N4Colore e forma:SolidPeso molecolare:377.31Pioglitazone potassium
CAS:Pioglitazone potassium is an oral PPARγ agonist with EC50 of 0.93 μM (human) and 0.99 μM (mouse), used in diabetes research.Formula:C19H19KN2O3SColore e forma:SolidPeso molecolare:394.53CDDO-Im
CAS:CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).Formula:C34H43N3O3Purezza:98.3% - 99.61%Colore e forma:SolidPeso molecolare:541.72(-)-Epicatechin
CAS:(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localizationFormula:C15H14O6Purezza:98.55% - 98.80%Colore e forma:SolidPeso molecolare:290.27UAMC-3203 hydrochloride
CAS:<p>UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.</p>Formula:C25H38ClN5O2SPurezza:99.62%Colore e forma:SolidPeso molecolare:508.12Baicalein monohydrate
CAS:Baicalein monohydrate blocks 12-lipoxygenase, curbs leukotrienes, lysosomal enzymes, Ca2+ dynamics, and fights arthritis.Formula:C15H12O6Colore e forma:SolidPeso molecolare:288.25Ferrostatin-1
CAS:Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of iron death, potently inhibits Erastin-induced iron death in HT-1080 cells. High-Quality, Low-Cost!Formula:C15H22N2O2Purezza:96.1% - 99.68%Colore e forma:SolidPeso molecolare:262.35CIL56
CAS:CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS).Formula:C23H27N3O5S2Purezza:99.46% - 99.91%Colore e forma:SolidPeso molecolare:489.61Hemin
CAS:Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.Formula:C34H32ClFeN4O4Purezza:97.169% - 99.59%Colore e forma:Dark Purple Crystalline PowderPeso molecolare:651.94DihydroarteMisinic acid
CAS:<p>DihydroarteMisinic acid (Dihydro-Artmisinic Acid) is a natural product from Artemisia annua and the main direct precursor of artemisinin, which is a medicinal</p>Formula:C15H24O2Purezza:99.06% - 99.17%Colore e forma:SolidPeso molecolare:236.35Arteannuin B
CAS:1. Arteannuin B has potent antimalarial activity.Formula:C15H20O3Purezza:98% - 99.8%Colore e forma:SolidPeso molecolare:248.32Eprenetapopt
CAS:Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.Formula:C10H17NO3Purezza:98.75% - 99.57%Colore e forma:SolidPeso molecolare:199.25DL-α-Tocopherol
CAS:<p>DL-alpha-Tocopherol (Ephanyl) is a synthetic vitamin E that protects skin fibroblasts from the cytotoxic effects of UV light and has antioxidant properties.</p>Formula:C29H50O2Purezza:99.61% - 99.90%Colore e forma:Light Yellow Liquid ViscousPeso molecolare:430.71SRS11-92
CAS:SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1Formula:C22H28N2O2Purezza:98.58%Colore e forma:SolidPeso molecolare:352.47Deferitrin
CAS:Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.Formula:C11H11NO4SPurezza:98.71%Colore e forma:SolidPeso molecolare:253.271R,3S-RSL 3
CAS:1R,3S-RSL 3 is a harmala alkaloid.Formula:C23H21ClN2O5Purezza:99.51%Colore e forma:SolidPeso molecolare:440.88Setanaxib
CAS:Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.Formula:C21H19ClN4O2Purezza:93.468% - 99.31%Colore e forma:SolidPeso molecolare:394.85Dp44mT
CAS:Dp44mT, a effective iron chelator, has selective antitumor activity.Formula:C14H15N5SPurezza:99% - 99.02%Colore e forma:SolidPeso molecolare:285.37Nordihydroguaiaretic acid
CAS:<p>Nordihydroguaiaretic acid (NDGA) is a natural lipoxygenase (5-LOX) inhibitor. Nordihydroguaiaretic acid has antioxidant effect. Cost-effective and quality-assured.</p>Formula:C18H22O4Purezza:97.82% - 99.91%Colore e forma:SolidPeso molecolare:302.36NADPH tetrasodium salt
CAS:<p>NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of</p>Formula:C21H26N7Na4O17P3Purezza:97.15% - >99.99%Colore e forma:SolidPeso molecolare:833.35SP-420
CAS:SP-420 is a novel orally active iron chelator.Formula:C16H21NO6SPurezza:99.39%Colore e forma:SolidPeso molecolare:355.41Troglitazone
CAS:Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.Formula:C24H27NO5SPurezza:98% - 99.8%Colore e forma:Yellow SolidPeso molecolare:441.54SRS16-86
CAS:<p>SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.</p>Formula:C26H32N4O2Purezza:97.73%Colore e forma:SolidPeso molecolare:432.56Pseudolaric Acid B
CAS:Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.Formula:C23H28O8Purezza:98.91% - 99.84%Colore e forma:SolidPeso molecolare:432.46Levobupivacaine
CAS:<p>Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide.</p>Formula:C18H28N2OPurezza:99.72%Colore e forma:SolidPeso molecolare:288.43PD146176
CAS:<p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>Formula:C15H11NSPurezza:98.00%Colore e forma:SolidPeso molecolare:237.32Rosiglitazone hydrochloride
CAS:Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.Formula:C18H19N3O3S·HClPurezza:99.63% - 99.79%Colore e forma:SolidPeso molecolare:393.89SP600125
CAS:SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitiveFormula:C14H8N2OPurezza:97.63% - 99.82%Colore e forma:SolidPeso molecolare:220.23L-Cystine
CAS:<p>L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation of</p>Formula:C6H12N2O4S2Purezza:99.59% - 99.85%Colore e forma:White Solid PowderPeso molecolare:240.30Rosiglitazone
CAS:<p>Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.</p>Formula:C18H19N3O3SPurezza:98.61% - 99.87%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:357.43L-Glutamic acid
CAS:<p>L-Glutamic acid is an agonist of glutamate receptors, including metabotropic glutamate receptors (mGluR), AMPA, NMDA, and KA. High-Quality, Low-Cost!</p>Formula:C5H9NO4Purezza:99.14% - 99.55%Colore e forma:White Solid CrystallinePeso molecolare:147.13ML385
CAS:ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity.Formula:C29H25N3O4SPurezza:98.08% - >99.99%Colore e forma:SolidPeso molecolare:511.59Trigonelline
CAS:<p>Trigonelline (Trigenolline), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.</p>Formula:C7H7NO2Purezza:97.585% - 99.49%Colore e forma:Prisms Aqueous From Alcohol + Water SolidPeso molecolare:137.14PRIMA-1
CAS:PRIMA-1 (NSC-281668) is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.Formula:C9H15NO3Purezza:99.22%Colore e forma:SolidPeso molecolare:185.22Atorvastatin hemicalcium salt
CAS:Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.Formula:C33H34FN2O5CaPurezza:99.27% - >99.99%Colore e forma:White Crystalline PowderPeso molecolare:577.67Erastin
CAS:Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner, anti-tumor. High-Quality, Low-Cost!Formula:C30H31ClN4O4Purezza:98% - 99.75%Colore e forma:SolidPeso molecolare:547.04FIN56
CAS:FIN56 is a specific inducer of ferroptosis.Formula:C25H31N3O5S2Purezza:99.72% - 99.78%Colore e forma:SolidPeso molecolare:517.66Chrysosplenetin
CAS:Chrysosplenetin is a metabolic inhibitor of artemisinin.Formula:C19H18O8Purezza:97.43% - 98.4%Colore e forma:SolidPeso molecolare:374.34Pifithrin-α hydrobromide
CAS:Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.Formula:C16H18N2OS·HBrPurezza:97.71% - >99.99%Colore e forma:SolidPeso molecolare:367.3Pifithrin-β hydrobromide
CAS:Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis.Formula:C16H17BrN2SPurezza:99.24% - 99.74%Colore e forma:SolidPeso molecolare:349.29Levobupivacaine hydrochloride
CAS:<p>Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.</p>Formula:C18H28N2O·HClPurezza:99.74%Colore e forma:White Crystalline PowderPeso molecolare:324.89Ammonium iron(III) citrate
CAS:Ammonium iron(III) citrate (Ferric ammonium citrate) is a physiological form of non-ferritin-bound iron that causes intracellular iron overload and iron death.Formula:C24H32Fe3N3O28Purezza:98%Colore e forma:Ferric Ammonium Citrate Is A Yellowish Brown To Red Solid With A Faint Odor Of AmmoniaPeso molecolare:978.05U-73122
CAS:U-73122 (U73122) , an effective PLC inhibitor, reduces agonist-induced Ca2+ increases in platelets and PMN.Formula:C29H40N2O3Purezza:97.50%Colore e forma:Solid Off-WhitePeso molecolare:464.64UAMC-3203
CAS:<p>UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).</p>Formula:C25H37N5O2SPurezza:97.052% - 99.72%Colore e forma:SolidPeso molecolare:471.66FINO2
CAS:FINO2, a strong ferroptosis trigger, blocks GPX4, oxidizes Fe2+, stable in different pH, causes lipid peroxidation.Formula:C15H28O3Purezza:97.27%Colore e forma:SoildPeso molecolare:256.38Microtubule inhibitor 8
CAS:<p>Microtubule Inhibitor 8 (MP-HJ-1b) serves as a potent disruptor of microtubule function, inducing cell death via ferroptosis and demonstrating anti-tumor effects [1] [2].</p>Formula:C21H15N3O2SColore e forma:SolidPeso molecolare:373.43Frataxin-IN-1
CAS:Frataxin-IN-1 inhibits the mitochondrial protein Frataxin with IC50 45 μM and is used in Friedreich’s ataxia research linked to mitochondrial defects.Formula:C20H23NO6Purezza:99.34%Peso molecolare:373.4Pioglitazone-d4
CAS:Pioglitazone D4 is a deuterium labeled Pioglitazone. Pioglitazone is a agonist of PPARγ .Formula:C19H20N2O3SPurezza:98%Colore e forma:SolidPeso molecolare:360.46W1131
CAS:W1131 is a potent STAT3 inhibitor and ferroptosis trigger, reducing cancer progression and 5-FU resistance.Formula:C23H19N5O4Colore e forma:SolidPeso molecolare:429.43Ferroptosis-IN-4
CAS:Ferroptosis-IN-4 (compound 6k), an inhibitor of ferroptosis, exhibits an EC50 of 20 μM and lacks significant cytotoxicity. It demonstrates a protective role in glycerol-induced RM-AKI mice by alleviating kidney dysfunction [1].Formula:C17H24ClN3O2Peso molecolare:337.84Anticancer agent 147
CAS:Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROSFormula:C32H40BrN3O2Purezza:98%Colore e forma:SolidPeso molecolare:578.58YL-939
YL-939 is a potent inhibitor of ferroptosis, targeting the PHB2/ferritin/iron axis to impede this form of cell death.Formula:C25H26N6OColore e forma:SolidPeso molecolare:426.51CGP 65015
CAS:CGP 65015 is an oral iron chelator and can mobilize iron deposits.Formula:C14H15NO4Purezza:98%Colore e forma:SolidPeso molecolare:261.27Ferroptosis inducer-1
CAS:Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .Formula:C25H21ClN2O5Colore e forma:SolidPeso molecolare:464.9Tubulin inhibitor 30
CAS:Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.Formula:C22H19N3O5Colore e forma:SolidPeso molecolare:405.4IM-93
CAS:IM-93 inhibits ferroptosis and NETosis with an IC< sub>50 of 0.45 μM for cell death inhibition [1].Formula:C21H28N4O2Colore e forma:SolidPeso molecolare:368.47CN128 hydrochloride
CAS:<p>CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.</p>Formula:C15H18ClNO3Colore e forma:SolidPeso molecolare:295.76BCP-T.A
CAS:<p>BCP-T.A is an iron death inducer that acts by binding to GPX4.</p>Formula:C23H19Cl2N3OSPurezza:99.49%Colore e forma:SolidPeso molecolare:456.39HBED
CAS:HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.Formula:C20H24N2O6Purezza:97.35% - 98.58%Colore e forma:SolidPeso molecolare:388.41Erastin2
CAS:<p>Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.</p>Formula:C36H35ClN4O4Purezza:99.63%Colore e forma:SolidPeso molecolare:623.14FA16
FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16Formula:C22H27F3N4O2SPurezza:99.44%Colore e forma:SolidPeso molecolare:468.54
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