NF-κB
Il fattore nucleare kappa-light-chain-enhancer delle cellule B attivate (NF-κB) è un fattore di trascrizione che regola l'espressione di geni coinvolti nelle risposte immunitarie, nell'infiammazione, nella sopravvivenza cellulare e nella proliferazione. NF-κB viene attivato in risposta a vari stimoli, tra cui citochine, agenti patogeni e segnali di stress. La disregolazione della segnalazione di NF-κB è associata a malattie infiammatorie croniche, cancro e disturbi autoimmuni. Presso CymitQuimica, offriamo una selezione completa di modulatori della via NF-κB per supportare la tua ricerca su infiammazione, oncologia e regolazione immunitaria.
Trovati 443 prodotti di "NF-κB"
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BAY-985
CAS:<p>BAY-985: potent oral TBK1/IKKε inhibitor; IC50s: TBK1 (2/30 nM), IKKε (2 nM); has antitumor properties.</p>Formula:C27H30F3N9OPurezza:99.62%Colore e forma:SolidPeso molecolare:553.58Asatone
CAS:<p>Asatone from Radix et Rhizoma Asari has anti-inflammatory properties, acting on NF-κB and suppressing p-MAPK pathways (ERK, JNK, p38).</p>Formula:C24H32O8Purezza:99.84% - 99.92%Colore e forma:SolidPeso molecolare:448.51Mevastatin
CAS:<p>Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.</p>Formula:C23H34O5Purezza:99.12%Colore e forma:White-Yellowish To Yellow Powder Solid PowderPeso molecolare:390.51Baicalin
CAS:<p>Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV</p>Formula:C21H18O11Purezza:90.08% - 99.32%Colore e forma:Yellow PowderPeso molecolare:446.36Lidocaine hydrochloride
CAS:<p>Lidocaine HCl: local anesthetic, antiarrhythmic, stronger & longer-lasting than procaine but shorter than bupivacaine/prilocaine.</p>Formula:C14H23ClN2OPurezza:99.81% - 99.92%Colore e forma:White Crystal PowderPeso molecolare:270.798GSK3145095
CAS:GSK3145095 is an orally active inhibitor of RIPK1 with IC50 of 5 nM, with potential immunomodulatory activities and antineoplastic.Formula:C20H17F2N5O2Purezza:99.50%Colore e forma:SolidPeso molecolare:397.38Theophylline
CAS:<p>Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central</p>Formula:C7H8N4O2Purezza:99.65% - 99.98%Colore e forma:White Solid PowderPeso molecolare:180.16Sulfasalazine
CAS:<p>Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.</p>Formula:C18H14N4O5SPurezza:98.00% - 99.28%Colore e forma:Minute Brownish-Yellow CrystalsPeso molecolare:398.39Metaxalone
CAS:<p>Metaxalone, sold as Skelaxin by King Pharmaceuticals, is a muscle relaxant for pain from strains and sprains.</p>Formula:C12H15NO3Purezza:98.84% - 99.94%Colore e forma:White To Almost White Crystalline Powder SolidPeso molecolare:221.25Mangiferin
CAS:<p>Mangiferin (Hedysarid) is used for antidiabetes. Extracted from Mangifera indica L.</p>Formula:C19H18O11Purezza:99.78% - 99.86%Colore e forma:Light Yellow PowderPeso molecolare:422.34Oxaprozin
CAS:<p>Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug.</p>Formula:C18H15NO3Purezza:98.53%Colore e forma:SolidPeso molecolare:293.32Urolithin B
CAS:Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropicalFormula:C13H8O3Purezza:99.45%Colore e forma:SolidPeso molecolare:212.2Aspirin
CAS:<p>Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.</p>Formula:C9H8O4Purezza:99.78% - 99.91%Colore e forma:White Solid CrystallinePeso molecolare:180.16CDDO-dhTFEA
CAS:CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor.Formula:C33H45F3N2O3Purezza:95.61% - 99.59%Colore e forma:SolidPeso molecolare:574.72NIK SMI1
CAS:<p>NIK SMI1 is an effective and selective NF-κB inducing kinase (NIK) inhibitor. It also inhibits NIK-catalyzed hydrolysis of ATP to ADP (IC50: 0.23±0.17 nM).</p>Formula:C20H19N3O4Purezza:99.04% - 99.99%Colore e forma:SolidPeso molecolare:365.38Theophylline monohydrate
CAS:<p>Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium</p>Formula:C7H8N4O2·H2OPurezza:99.78%Colore e forma:SolidPeso molecolare:198.18α-Lipoic Acid
CAS:<p>α-Lipoic Acid, a sulfur-containing octanoic acid derivative, is biosynthesized from linoleic acid and used in dietary supplements.</p>Formula:C8H14O2S2Purezza:98.39% - 99.73%Colore e forma:Forms Yellowish Flakes Light Yellow To Yellow PowderPeso molecolare:206.33IMD-0560
CAS:<p>IMD-0560 is a novel inhibitor of IκB kinase β.</p>Formula:C15H8BrF6NO2Purezza:99.51%Colore e forma:SolidPeso molecolare:428.12Guaiacol
CAS:<p>Guaiacol, a flavorant precursor, has medicinal uses and serves as an oxygen indicator turning yellow-brown at 470 nm.</p>Formula:C7H8O2Purezza:99.95%Colore e forma:Colourless To Pale Yellow Solid CrystallinePeso molecolare:124.14Sinomenine hydrochloride
CAS:<p>Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.</p>Formula:C19H24ClNO4Purezza:99.43%Colore e forma:SolidPeso molecolare:365.851Nimbolide
CAS:<p>Nimbolide, from neem, inhibits CDK4/6, NF-κB, Wnt, PI3K-Akt, MAPK, JAK-STAT pathways and induces apoptosis.</p>Formula:C27H30O7Purezza:95.84% - 99.4%Colore e forma:SolidPeso molecolare:466.525-Aminosalicylic Acid
CAS:<p>5-Aminosalicylic Acid (5-ASA) is a specific PPARγ agonist and also inhibits P21-activated kinase 1 (PAK1) and NF-Κb. High-Quality, Low-Cost!</p>Formula:C7H7NO3Purezza:98.88% - 99.49%Colore e forma:Purplish-Tan Solid PowderPeso molecolare:153.14SN50 acetate (213546-53-3 free base)
<p>SN50 acetate is a cell permeable inhibitor of NF-κB translocation.</p>Formula:C131H234N36O31SPurezza:99.86%Colore e forma:SolidPeso molecolare:2841.55Erdosteine
CAS:<p>Erdosteine (RV 144), a mucolytic thiol, modulates mucus and aids expectoration, reduces cough, and protects lungs from smoke damage.</p>Formula:C8H11NO4S2Purezza:99.43% - 99.94%Colore e forma:White Or Almost White Crystalline PowderPeso molecolare:249.314-Hydroxychalcone
CAS:<p>4-Hydroxychalcone (P-Cinnamoylphenol) attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.</p>Formula:C15H12O2Purezza:99.75%Colore e forma:Yellow PowderPeso molecolare:224.25Articaine hydrochloride
CAS:<p>Articaine hydrochloride (Hoe-045) is a thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.</p>Formula:C13H21ClN2O3SPurezza:99.76%Colore e forma:White Crystalline PowderPeso molecolare:320.84TBK1/IKKε-IN-2
CAS:<p>TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.</p>Formula:C26H27N5O3Purezza:98.89%Colore e forma:SolidPeso molecolare:457.52Sodium salicylate
CAS:<p>Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.</p>Formula:C7H5NaO3Purezza:99.36% - 99.92%Colore e forma:White Solid AmorphousPeso molecolare:160.11Lidocaine Hydrochloride hydrate
CAS:<p>Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.</p>Formula:C14H22N2O·HCl·H2OPurezza:99.95%Colore e forma:SolidPeso molecolare:288.82Sulindac
CAS:<p>Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.</p>Formula:C20H17FO3SPurezza:99.09% - 99.15%Colore e forma:Yellow SolidPeso molecolare:356.41Dihydroartemisinin
CAS:<p>Dihydroartemisinin (Artenimol) is an antimalarial drug. High-Quality, Low-Cost!</p>Formula:C15H24O5Purezza:98% - 99.41%Colore e forma:White SolidPeso molecolare:284.35Naringin dihydrochalcone
CAS:<p>Naringin dihydrochalcone (Naringin DC) is an inhibitor of CYP enzymes, used as an artificial sweetener.</p>Formula:C27H34O14Purezza:99.07% - 99.73%Colore e forma:Solid PowderPeso molecolare:582.55DCZ0415
CAS:<p>DCZ0415: Potent TRIP13 inhibitor; combats myeloma in vitro, in vivo, and in drug-resistant patients; hinders DNA repair and NF-κB activity.</p>Formula:C23H20N2O2Purezza:99.34% - 99.95%Colore e forma:SolidPeso molecolare:356.42Lidocaine
CAS:<p>Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil influx.</p>Formula:C14H22N2OPurezza:99.95% - >99.99%Colore e forma:Needles From Benzene Or Alcohol SolidPeso molecolare:234.34GLPG2534
CAS:<p>GLPG2534 is an orally active, selective and potent IRAK4 inhibitor with anti-inflammatory activity. GLPG2534 can be used in psoriasis and atopic dermatitis.</p>Formula:C21H24N6O4Purezza:99.51% - 99.61%Colore e forma:SolidPeso molecolare:424.45(E/Z)-BCI
CAS:<p>(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROS</p>Formula:C22H23NOPurezza:99.94%Colore e forma:SolidPeso molecolare:317.42DRI-C21045
CAS:<p>Dri-c21045 inhibits NF-kB (IC50=17.1μM) and B cell proliferation (IC50=4.5μM), selectively blocking CD40-CD40L interaction (IC50=0.17μM).</p>Formula:C32H24N2O7SPurezza:97.20%Colore e forma:SolidPeso molecolare:580.61Ergolide
CAS:<p>Ergolide, from Inula Britannica, inhibits iNOS and COX-2 by deactivating NF-κB in macrophages.</p>Formula:C17H22O5Purezza:99.64%Colore e forma:SolidPeso molecolare:306.35Methylthiouracil
CAS:<p>Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.</p>Formula:C5H6N2OSPurezza:99.89% - >99.99%Colore e forma:Crystals Saturated Aqueous Solution Is Neutral Or Slightly Acidic (Ntp 1992)Peso molecolare:142.18Indacaterol maleate
CAS:<p>Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.</p>Formula:C28H32N2O7Purezza:99.03% - 99.67%Colore e forma:SolidPeso molecolare:508.56AZ1495
CAS:<p>AZ1495: oral IRAK4 inhibitor (IC50: 5 nM), IRAK1 (23 nM), treats MYD88L265P DLBCL.</p>Formula:C21H31N5O2Purezza:98.81%Colore e forma:SolidPeso molecolare:385.5RIPK1-IN-7
CAS:<p>RIPK1-IN-7: Strong, selective RIPK1 inhibitor (Kd=4 nM, IC50=11 nM) with great antimetastasis effects in B16 melanoma.</p>Formula:C25H22F3N5O2Purezza:98.02% - 98.18%Colore e forma:SolidPeso molecolare:481.47DMAPT
CAS:<p>DMAPT is a water-soluble PTL analogue, orally active NF-κB inhibitor with 1.7 μM LD50 in acute myeloid leukemia cells.</p>Formula:C17H27NO3Purezza:99.91%Colore e forma:SolidPeso molecolare:293.4IRAK4-IN-4
CAS:<p>IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4)</p>Formula:C22H16N2O2Purezza:99.52%Colore e forma:SolidPeso molecolare:340.37NF-κB Signaling Compound Library
<p>A unique collection of xnum compounds targeting NF-κB signaling for high throughput screening and high content screening;</p>Colore e forma:Odour Solid12-Oxo phytodienoic acid
CAS:<p>12-oxo PDA boosts alkaloid production in E. californica, enhances B. dioica tendril curls, and blocks JA-induced cell death in A. fru mutants.</p>Formula:C18H28O3Purezza:98%Colore e forma:SolidPeso molecolare:292.41CAY10512
CAS:<p>CAY10512, a resveratrol analog, is 100x more potent, inhibiting NF-κB with an IC50 of 0.15 μM versus resveratrol's 20 μM.</p>Formula:C15H13FOColore e forma:SolidPeso molecolare:228.266Murrayafoline A
CAS:<p>Murrayafoline A is a useful organic compound for research related to life sciences. The catalog number is T124835 and the CAS number is 4532-33-6.</p>Formula:C14H13NOColore e forma:SolidPeso molecolare:211.2643-(2-Hydroxyethyl) thio withaferin A
<p>3-(2-Hydroxyethyl) thio withaferin A, a steroidal lactone, blocks NF-kB, targets vimentin, and inhibits EPCR shedding.</p>Formula:C30H44O7SColore e forma:SolidPeso molecolare:548.73Helenalin
CAS:<p>Helenalin: anti-inflammatory sesquiterpene, inhibits NF-κB by alkylating p65 cysteine groups, blocks DNA binding.</p>Formula:C15H18O4Purezza:98%Colore e forma:SolidPeso molecolare:262.3Ginger extract
CAS:<p>Ginger extract demonstrates (exhibits) anti-cancer, anti-inflammatory, and chemotherapeutic properties in living organisms (in vivo).</p>Colore e forma:SolidLicoagrochalcone C
CAS:<p>Licoagrochalcone C, a flavonoid, inhibits NF-κB and NO production effectively.</p>Formula:C21H22O5Colore e forma:SolidPeso molecolare:354.4CAY10657
CAS:<p>CAY10657 has a wide range of applications in life science related research.</p>Formula:C17H20N4O3SColore e forma:SolidPeso molecolare:360.43CIB-1476
<p>CIB-1476, a caspase-1 inhibitor, effectively reduces joint swelling in mouse models of arthritis and demonstrates lasting anti-inflammatory effects. This compound achieves its benefits by blocking IL-1β production, NF-κB activation, and GSDMD-mediated pyroptosis, all of which are triggered by the NLRP3 inflammasome.</p>Formula:C28H28N2O6SColore e forma:SolidPeso molecolare:520.6IKK-IN-3
CAS:<p>IKK-IN-3: potent IKK2 inhibitor (IC50=19nM), affects IKK1(IC50=400nM).</p>Formula:C17H17N5SColore e forma:SolidPeso molecolare:323.42Anti-inflammatory agent 48
<p>Anti-inflammatory agent 48 functions by inhibiting the NF-κB signaling pathway and activating HO-1 expression, characterizing its role as an anti-inflammatory</p>Formula:C24H21Cl2NO3Purezza:98%Colore e forma:SolidPeso molecolare:442.33Cyclo(L-Pro-L-Val)
CAS:<p>Cyclo(L-Pro-L-Val), from Mycobacterium spp., has anti-inflammatory effects, hinders phytopathogens, and suppresses IKKα, NF-κB, iNOS, and COX-2 activation.</p>Formula:C10H16N2O2Purezza:98.18%Colore e forma:SolidPeso molecolare:196.257-O-Methylaloeasinol
CAS:<p>7-O-Methylaloeasinol is a useful organic compound for research related to life sciences. The catalog number is T126468 and the CAS number is 105317-69-9.</p>Formula:C20H26O9Colore e forma:SolidPeso molecolare:410.419NLRP3-IN-51
<p>NLRP3-IN-51 (Compound 3q) is an effective activator of the cholinergic anti-inflammatory pathway (CAP). This compound demonstrates potential for treating gouty arthritis as it inhibits the production of IL-1β in THP-1 cells induced by monosodium urate (MSU). Furthermore, NLRP3-IN-51 suppresses the phosphorylation of NF-κBp65 triggered by MSU without impacting the self-cleavage and activation of NLRP3, pro-caspase 1, or the second messenger caspase-1. Therefore, the initial stage of NLRP3 inhibition by NLRP3-IN-51 occurs through the activation of CAP.</p>Colore e forma:Odour Solid17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
CAS:<p>DPA metabolite 17-oxo-DPA, found in fish oil, spurs antioxidant genes, modulates inflammation, and activates PPARγ (EC50 ≈ 200 nM).</p>Formula:C22H32O3Colore e forma:SolidPeso molecolare:344.495IVMT-Rx-3
<p>IVMT-Rx-3 is a chemical compound that serves as an inhibitor of SDCBP's targeting of the PDZ1 and PDZ2 domains of MDA-9/Syntenin.</p>Formula:C69H90F3N13O24Purezza:98%Colore e forma:SoildPeso molecolare:1542.54R1-ICR-5
CAS:<p>R1-ICR-5 is a selective PROTAC degrader targeting serine/threonine-protein kinase 1 (RIPK1). Mediated by VHL, R1-ICR-5 promotes the degradation of RIPK1, disrupting the TNFR1 and TLR3/4 signaling hubs, enhancing NF-κB, MAPK, and IFN signal output, and facilitating RIPK3 activation and necroptosis induction. R1-ICR-5 holds potential for research in cancer and inflammatory diseases.</p>Formula:C54H70N8O7S2Colore e forma:SolidPeso molecolare:1007.31COX-2-IN-48
<p>COX-2-IN-48 (5-25) serves as an inhibitor of COX-2, exhibiting an IC50 of 51.7 nM against human COX-2. It displays anti-inflammatory and analgesic effects in various rodent models through inhibition of the NF-κB pathway. COX-2-IN-48 (5-25) inhibits the degradation of IκB, phosphorylation and nuclear translocation of NF-κB p65, and the expression of COX-2 and iNOS.</p>Colore e forma:Odour SolidAnti-osteoporosis agent-4
<p>Anti-osteoporosis agent-4 (Compound 11h) suppresses the differentiation of primary osteoclasts and attenuates RANKL-induced osteoclastogenesis.</p>Formula:C26H26ClN3O7SPurezza:98%Colore e forma:SolidPeso molecolare:560.02N-Acetyldopamine dimer-2
CAS:<p>Compound 2, an N-acetyldopamine dimer from Periostracum Cicadae, exhibits antioxidant and anti-inflammatory properties.</p>Formula:C20H20N2O6Colore e forma:SolidPeso molecolare:384.38(−)-N-Hydroxyapiosporamide
CAS:<p>(−)-N-Hydroxyapiosporamide (NHAP), an alkaloid, serves as an NF-κB inhibitor and demonstrates significant antitumor activity both in vitro and in vivo.</p>Formula:C24H31NO7Purezza:98%Colore e forma:SolidPeso molecolare:445.51LY2409881
CAS:<p>LY2409881 is a selective IκB kinase β ( IKK2 ) inhibitor with an IC 50 of 30 nM.</p>Formula:C24H29ClN6OSColore e forma:SolidPeso molecolare:485.05Anti-inflammatory agent 7
<p>Anti-inflammatory Agent 7 suppresses proinflammatory cytokines by hindering the NF-κB/MAPK signaling pathway in both LPS-treated RAW 264.7 cells and mice.</p>Formula:C36H40N4O9Colore e forma:SolidPeso molecolare:672.72Diprovocim-1
CAS:<p>Diprovocim-1: TLR1/2 agonist; triggers TNF-α in THP-1 cells; boosts ovalbumin IgG1 & CTLs against tumors with anti-PD-L1 in mice.</p>Formula:C56H56N6O6Colore e forma:SolidPeso molecolare:909.1Pratensein
CAS:<p>Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.</p>Formula:C16H12O6Purezza:99.90%Colore e forma:SolidPeso molecolare:300.26SN50 TFA
<p>SN50 TFA is an inhibitor of NF-κB and attenuates alveolar hypercoagulation and fibrinolysis inhibition. SN50 TFA can be used in studies about ARDS.</p>Formula:C129H230N36O29S·XCF3COOHColore e forma:SolidPeso molecolare:2781.5 (free base)RIPK1-IN-25
<p>RIPK1-IN-25 (WL8) is a RIPK1 inhibitor with blood-brain barrier permeability, displaying an EC50 of 19.9 nM and a Kd of 25 nM. It is utilized in the research of neurodegenerative diseases.</p>Colore e forma:Odour SolidSU1261
<p>SU1261, an IKK inhibitor, exhibits Ki values of 10 nM for IKKα and 680 nM for IKKβ. It effectively inhibits non-canonical NF-κB signaling in U2OS osteosarcoma cells.</p>Colore e forma:Odour SolidTBK1/IKKε-IN-6
CAS:<p>TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.</p>Formula:C31H36F2N8O4Colore e forma:SolidPeso molecolare:622.678Eupenicisirenin C
CAS:Eupenicisirenin C (compound 1), a sirenin derivative, exhibits strong NF-κB inhibitory activities and suppresses the cGAS-STING pathway. Additionally, Eupenicisirenin C inhibits RANKL-induced osteoclast differentiation in bone marrow macrophage cells [1].Formula:C13H18O4Peso molecolare:238.28Narlumosbart
CAS:<p>Narlumosbart (JMT103) is an IgG4κ monoclonal antibody that selectively binds to the receptor activator of nuclear factor-κB ligand (RANKL)[1].</p>Purezza:98%Colore e forma:LiquidIRAK4-IN-26
<p>IRAK4-IN-26 (Compound 21), an IRAK4 inhibitor with an IC50 of 6.2 nM, exhibits an oral bioavailability of 21%.</p>Formula:C22H23N5O3Purezza:98%Colore e forma:SolidPeso molecolare:405.45CTP-NBD
CAS:<p>CTP-NBD is a cell-permeable, specific inhibitor of the NFκB peptide, which has been utilized in studies of colitis [1] [2].</p>Formula:C121H194N46O32Purezza:98%Colore e forma:SolidPeso molecolare:2805.12NF-κB-IN-12
<p>NF-κB-IN-12 (compound 3h) serves as a potent inhibitor of NF-κB, exhibiting an IC50 value of 1.02 μM. It is applicable for research in acute lung injury [1].</p>Formula:C30H26N6O5SPurezza:98%Colore e forma:SolidPeso molecolare:582.63Sanggenon A
CAS:<p>Sanggenon A (Sanggenone A) exhibits anti-inflammatory properties by modulating the NF-κB and HO-1/Nrf2 signaling pathways in BV2 and RAW264.7 cells, and it</p>Formula:C25H24O7Purezza:98%Colore e forma:SolidPeso molecolare:436.45Mitogen-activated protein kinase 1
CAS:<p>Mitogen-activated protein kinase 1 (MAPK1) activates the p38/NF-κB pathway and regulates cellular processes in sepsis-associated diseases.</p>Purezza:98%Colore e forma:SolidIRAK4-IN-24
<p>IRAK4-IN-24 (compound 16), a potent IRAK4 inhibitor, exhibits high clearance (Cl) and low oral bioavailability.</p>Formula:C19H19N5O3Purezza:98%Colore e forma:SolidPeso molecolare:365.39Salicortin
CAS:<p>Salicortin, a phenolic glycoside from Populus and Salix, has anti-adipogenic, anti-amnesic, and immune effects.</p>Formula:C20H24O10Purezza:98%Colore e forma:SolidPeso molecolare:424.40IRAK4-IN-25
<p>IRAK4-IN-25 (compound 38), a potent oral IRAK4 inhibitor (IC50 = 7.3 nM) with low clearance (Cl = 12 mL/min/kg), effectively suppresses pro-inflammatory</p>Formula:C23H25N5O4Purezza:98%Colore e forma:SolidPeso molecolare:435.48RIPK2-IN-5
CAS:<p>RIPK2-IN-5 is a receptor-interacting protein kinase 2 (RIPK2) inhibitor with potential anti-inflammatory activity for the study of diseases caused by immune dysfunctions.</p>Formula:C21H14N4SPurezza:98.85%Colore e forma:SoildPeso molecolare:354.43Siegesbeckialide I
<p>Siegesbeckialide I effectively suppresses LPS-induced NO production in RAW264.7 murine macrophages by directly interacting with IKKα/β.</p>Formula:C20H28O6Colore e forma:SolidPeso molecolare:364.43RIPK2/3-IN-1
<p>RIPK2/3-IN-1 is a potent inhibitor of both RIPK2 and RIPK3 kinases, exhibiting IC50 values of 3 nM for RIPK2 and 117 nM for RIPK3.</p>Formula:C24H16N4O2S2Purezza:98%Colore e forma:SolidPeso molecolare:456.54NF-κB-IN-10
<p>NF-κB-IN-10 (compound E1) is an inhibitor of NF-κB that mitigates heart failure symptoms through the modulation of the Nrf2/NF-κB signaling pathway, alleviating</p>Formula:C26H30N2O4Purezza:98%Colore e forma:SolidPeso molecolare:434.53SjDX5-271
CAS:<p>SjDX5-271 is a 3 kDa peptide that inhibits the TLR4/MyD88/NF-κB signaling pathway. It induces cell polarization, alleviates liver inflammation, and protects mice from liver ischemia-reperfusion injury.</p>Formula:C137H215N47O49SColore e forma:SolidPeso molecolare:3336.52NBD peptide
CAS:<p>NBD peptide inhibits the NF-κB signaling pathway by preventing the binding of the NEMO-IKK complex. It exhibits anti-inflammatory activity by blocking the production of pro-inflammatory cytokines. Additionally, NBD peptide demonstrates immunosuppressive effects through the regulation of immune cells. It enhances transmembrane capacity by conjugating with the cell-penetrating peptide HIV-TAT.</p>Formula:C62H88N14O20Colore e forma:SolidPeso molecolare:1349.44IKKγ NBD Inhibitory Peptide
CAS:<p>A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF</p>Formula:C170H259N49O42S1Purezza:98%Colore e forma:SolidPeso molecolare:3693.3Mesalamine impurity P
CAS:<p>Mesalamine impurity P, a 5-Aminosalicylic acid derivative, is a PPARγ agonist, inhibiting PAK1 and NF-κB.</p>Formula:C13H11NO6SColore e forma:SolidPeso molecolare:309.30Anti-osteoporosis agent-8
Anti-osteoporosis agent-8 (Compound 4aa) is a RANKL inhibitor, capable of preventing RANKL-induced osteoclastogenesis and osteoclast differentiation, with an IC50 of 2.41 μM. Furthermore, Anti-osteoporosis agent-8 has been shown to mitigate bone loss in an ovariectomized (OVX) mouse model.Formula:C18H19F3N2O2SePeso molecolare:432.05638OT-551 HCl
CAS:<p>OT-551 HCl is an NF-Κb inhibitor, a disubstituted hydroxylamine with antioxidant properties can be used for the treatment of cataracts and age-related macular</p>Formula:C13H24ClNO3Purezza:99.71%Colore e forma:SolidPeso molecolare:277.79Sootepin D
CAS:<p>Sootepin D is a triterpene from the apical bud of Gardenia sootepensis, and is TNF-α-induced NF-κB inhibitor(IC50 of 8.3μM),with anti-inflammatory activity.</p>Formula:C31H48O4Purezza:98%Colore e forma:SolidPeso molecolare:484.71Anti-inflammatory agent 60
<p>Anti-inflammatory agent 60 (compound 21) inhibits nitric oxide production, presenting an IC50 of 12.95 μM, and reduces iNOS, phosphorylated p65, and β-catenin</p>Purezza:98%Colore e forma:Odour SolidNF-κB-IN-9
<p>NF-κB-IN-9, a nuclear factor kappa B (NF-κB) targeting sonosensitizer with excitation and emission wavelengths (λex/λem) of 489/628 nm, features dual</p>Formula:C62H50N4O4SColore e forma:SolidPeso molecolare:947.15TH023
<p>TH023 is an inhibitor of the TLR4 signaling pathway, specifically targeting the formation of TLR4 homodimers. In HEK-Blue hTLR4 cells, TH023 suppresses the secretion of embryonic alkaline phosphatase with an IC50 of 0.354 μM and inhibits NO expression in RAW264.7 cells, with an IC50 of 1.61 μM. Additionally, TH023 inhibits the activation of NF-κB and reduces the nuclear translocation of NF-κB p65. The compound demonstrates anti-inflammatory effects in a mouse model of LPS-induced acute sepsis and improves lung injury in mice.</p>Formula:C22H21ClF2N4OColore e forma:SolidPeso molecolare:430.88Antidesmone
CAS:<p>Antidesmone from Ajuga decumbens inhibits acute lung injury by modulating MAPK and NF-κB.</p>Formula:C19H29NO3Purezza:98%Colore e forma:SolidPeso molecolare:319.44Aloenin aglycone
CAS:<p>Aloenin aglycone (compound 13), an inhibitor of NF-κB, can be sourced from aloe exudate.</p>Formula:C13H12O5Purezza:98%Colore e forma:SolidPeso molecolare:248.23PS 1145 dihydrochloride
CAS:<p>IκB kinase (IKK) inhibitor</p>Formula:C17H13Cl3N4OPurezza:98%Colore e forma:SolidPeso molecolare:395.67Nasunin
CAS:<p>Delphanin, also known as Nasunin, is an anthocyanin isolated as purple colored crystals from eggplant peels.</p>Formula:C42H47ClO23Colore e forma:SolidPeso molecolare:955.26PROTAC IRAK4 ligand-4
CAS:<p>PROTAC IRAK4 ligand-4, a Ligand for Target Protein for PROTAC (Ligand for Target Protein for PROTAC), exhibits anti-tumor activity and is utilized in synthesizing PROTAC IRAK4 degrader-12. This compound serves as a targeted ligand with specific applications in the development of cancer therapeutics.</p>Formula:C24H26F2N6O3Colore e forma:SolidPeso molecolare:484.5MRT67307
CAS:<p>Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy.</p>Formula:C26H36N6O2Purezza:99.25% - 99.84%Colore e forma:SolidPeso molecolare:464.6Transcription Factor-Targeted Compound Library
<p>Well-chosen xnum compounds with unique structures targeting transcription factor;</p>Colore e forma:Odour SolidNF-κΒ activator 1
CAS:<p>NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.</p>Formula:C16H11FN2O2SPurezza:99.58%Colore e forma:SolidPeso molecolare:314.33Anti-inflammatory agent 51
CAS:<p>Anti-inflammatory agent 51 amide/sulfonamide anti-inflammatory and anti-tumor activity inhibition of NF-κB activation acute lung injury and ulcerative colitis.</p>Formula:C22H22N6O6SPurezza:99.46%Colore e forma:SoildPeso molecolare:498.51PROTAC STING degrader-3
<p>PROTACSTING degrader-3 (Compound ST9) is a STINGPROTAC-type degrader with a DC50 of 0.62 μM. It induces STING degradation via the ubiquitin-proteasome pathway. This compound exerts anti-inflammatory effects by inhibiting the STING/TBK1/NF-κB signaling. Additionally, it offers renal protection and can be used in research on acute kidney injury.</p>Colore e forma:Odour SolidLemnalol
CAS:<p>Lemnalol, from Lemnalia cervicorni, has anti-inflammatory and analgesic properties.</p>Formula:C15H24OPurezza:98%Colore e forma:SolidPeso molecolare:220.35HS-243
CAS:<p>HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.</p>Formula:C17H16N4O3Purezza:98.62%Colore e forma:SolidPeso molecolare:324.33Coronalolic acid
CAS:<p>Coronalolic acid is a natural product extracted from the Gardenia sootepenesis Hutch. It inhibits TNF-α-induced NF-κB activity and NO production.</p>Formula:C30H46O4Purezza:98%Colore e forma:SolidPeso molecolare:470.68(R)-(-)-Ibuprofen
CAS:<p>(R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation.</p>Formula:C13H18O2Purezza:99.86%Colore e forma:SolidPeso molecolare:206.28EN450
CAS:<p>EN450 is a targeted cysteine degrader of NF-κB with antiproliferative activity and potential anticancer activity for the study of leukemia.</p>Formula:C11H13ClN2O3SPurezza:99.72%Colore e forma:SoildPeso molecolare:288.75PROTAC IRAK4 degrader-12
CAS:<p>PROTAC IRAK4 degrader-12, a Cereblon ligand-based PROTAC, induces a maximum degradation of IRAK4 in K562 cells at 108.46% with an IC50 value of 4.87 nM. (Structure Note: Pink, IRAK4 Inhibitor; Blue, E3; Black, linker.)</p>Formula:C46H50ClF2N11O6Colore e forma:SolidPeso molecolare:926.41MJ210
<p>MJ210 is an orally active and blood-brain barrier-permeable modulator of the NF-κB and MAPK pathways, exhibiting neuroprotective properties. In vitro, 5 μM MJ210 can increase the survival rate of rotenone-treated SH-SY5Y cells to 81.9% and reduce levels of ROS. In vivo, 5 mg/kg MJ210 improves motor dysfunction in rat models of Parkinson's disease. MJ210 is useful for research in neurological disorders, including Parkinson's disease.</p>Colore e forma:Odour SolidRIPK1-IN-27
<p>RIPK1-IN-27 (compound 19) is an inhibitor of RIPK1.</p>Formula:C27H28N4O3Colore e forma:SolidPeso molecolare:456.54Gliotoxin
CAS:<p>Gliotoxin, a mycotoxin, inhibits Wnt pathway, causing apoptosis in mutated colorectal cancer cells and blocks NF-κB by preserving IκB.</p>Formula:C13H14N2O4S2Purezza:98%Colore e forma:SolidPeso molecolare:326.39R-HP210
<p>R-HP210 blocks LPS-triggered IL-1β, IL-6, COX-2 gene transcription and has a 3.80 μM IC50 for NF-κB inhibition without activating GCs.</p>Formula:C22H19N3O2S2Colore e forma:SolidPeso molecolare:421.54HOIPIN-1
CAS:<p>HOIPIN-1 (JTP0819958) is a selective and potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) (IC50 >2.8 μM).HOIPIN-1 inhibits LUBAC-mediated NF-</p>Formula:C17H13NaO4Purezza:98.83%Colore e forma:SoildPeso molecolare:304.27IRAK4-IN-10
CAS:<p>IRAK4-IN-10, a potent IRAK4 blocker with IC50 of 1.5 nM, may treat inflammation, autoimmunity, and cancer.</p>Formula:C22H24N8Purezza:98.55%Colore e forma:SolidPeso molecolare:400.48IRAK4-IN-8
CAS:<p>IRAK4-IN-8 (VI-177) is an IRAK4 inhibitor for the study of diseases associated with cancer and inflammation.</p>Formula:C23H23F2N7O2SPurezza:99.33%Colore e forma:SolidPeso molecolare:499.54IRAK inhibitor 2
CAS:<p>IRAK inhibitor 2 (IRAK-IN-2) is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK-4) for the study of inflammation-related diseases.</p>Formula:C17H14N4O2Purezza:97.90% - 99.58%Colore e forma:SolidPeso molecolare:306.32DTP3
CAS:<p>DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.</p>Formula:C26H35N7O5Colore e forma:SolidPeso molecolare:525.6ML 120B dihydrochloride
CAS:<p>MLN120B dihydrochloride: oral IKKβ inhibitor with 60 nM IC50, suppresses myeloma growth, used in arthritis research.</p>Formula:C19H17Cl3N4O2Colore e forma:SolidPeso molecolare:439.72Hesperidin methylchalcone
CAS:Hesperidin methylchalcone, from Citrus, is a potent antioxidant that inhibits NF-κB to alleviate gout arthritis in mice.Formula:C29H36O15Purezza:99.53%Colore e forma:Yellow PowderPeso molecolare:624.59RS 09
CAS:<p>TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. Acts as an adjuvant in vivo; enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.</p>Formula:C31H49N9O9Purezza:98%Colore e forma:SolidPeso molecolare:691.78BIZ 114
CAS:<p>BIZ 114 potently inhibits the TNF-α activated NF-κΒ pathway. BIZ 114 has the potential to prevent and/or treat ophthalmic disorders.</p>Formula:C24H40O3Colore e forma:SolidPeso molecolare:376.57Edecesertib
CAS:<p>Edecesertib (GS 5718) is an IRAK-4 inhibitor with anti-inflammatory activity for the study of rheumatoid arthritis.</p>Formula:C22H22FN7O2Purezza:98.84% - 99.94%Colore e forma:SolidPeso molecolare:435.45TOMATIDINE HYDROCHLORIDE
CAS:<p>Tomatidine hydrochloride (Tomatidine HCl) is a steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway.</p>Formula:C27H46ClNO2Purezza:99.75% - ≥95%Colore e forma:SolidPeso molecolare:452.11Cornuside
CAS:<p>Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.</p>Formula:C24H30O14Purezza:99.86% - >99.99%Colore e forma:SolidPeso molecolare:542.49QNZ
CAS:<p>QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.</p>Formula:C22H20N4OPurezza:99.17% - 99.18%Colore e forma:White SolidPeso molecolare:356.42BEC hydrochloride
CAS:<p>BEC hydrochloride (BEC HCl) is a competitive arginase inhibitor, which bind slowly. Ki of BEC HCl is 0.31 μM (pH7.5) for Arginase II.</p>Formula:C5H12BNO4S·ClHPurezza:98.65% - 99.28%Colore e forma:SolidPeso molecolare:229.49Bortezomib
CAS:<p>Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.</p>Formula:C19H25BN4O4Purezza:97.79% - >99.99%Colore e forma:Yellow SolidPeso molecolare:384.24CAFESTOL
CAS:<p>Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.</p>Formula:C20H28O3Purezza:97.06% - 99.08%Colore e forma:SolidPeso molecolare:316.43Demethyleneberberine
CAS:<p>Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either</p>Formula:C19H18NO4Purezza:98.08% - 99.18%Colore e forma:SolidPeso molecolare:324.35Morusin
CAS:<p>Morusin shows anti-tumor, antioxidant, and anti-inflammatory properties by inhibiting STAT3, NFκB, and inducing apoptosis.</p>Formula:C25H24O6Purezza:98.68% - 99.8%Colore e forma:SolidPeso molecolare:420.45EUK-134
CAS:EUK-134, a synthetic SOD/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.Formula:C18H18ClMnN2O4Purezza:98.39%Colore e forma:SolidPeso molecolare:416.74Flavanomarein
CAS:<p>Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.</p>Formula:C21H22O11Purezza:98.63% - 99.54%Colore e forma:SolidPeso molecolare:450.39Ginsenoside Rk3
CAS:Ginsenosides Rk3 & Rh4 may treat inflammation and ischemic heart disease.Formula:C36H60O8Purezza:99.88%Colore e forma:SolidPeso molecolare:620.86Quinoclamine
CAS:<p>Quinoclamine is a naphthoquinone derivative and is an NF-κB inhibitor.</p>Formula:C10H6ClNO2Purezza:99.13% - 99.28%Colore e forma:Orange PowderPeso molecolare:207.613'-Sialyllactose
CAS:<p>3'-Sialyllactose (3'-SL), a prebiotic, supports immunity, reduces inflammation and arthritis, and is low-toxicity for research.</p>Formula:C23H39NO19Colore e forma:SolidPeso molecolare:633.55OPHIOPOGONIN D
CAS:<p>Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.</p>Formula:C44H70O16Purezza:99.46% - ≥95%Colore e forma:SolidPeso molecolare:855.02Rocaglamide
CAS:<p>Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.</p>Formula:C29H31NO7Purezza:95.32% - 99.67%Colore e forma:SolidPeso molecolare:505.56BI-69A11
CAS:<p>BI-69A11 is a dual AKT/NFkB inhibitor, increasing colon cancer cell sensitivity to mda-7/IL-24.</p>Formula:C25H16ClN3O2Purezza:96.97%Colore e forma:SolidPeso molecolare:425.87Benzoyloxypaeoniflorin
CAS:<p>Benzoyloxypaeoniflorin, a natural compound, enhances blood flow by inhibiting platelet aggregation and coagulation.</p>Formula:C30H32O13Purezza:98.52% - 99.96%Colore e forma:SolidPeso molecolare:600.57IMM-H007
CAS:<p>IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression</p>Formula:C22H23N5O8Purezza:97.73%Colore e forma:SolidPeso molecolare:485.45Convallatoxin
CAS:<p>Convallatoxin is a natural product.</p>Formula:C29H42O10Purezza:99.27% - 99.53%Colore e forma:Prisms From Methanol + Ether SolidPeso molecolare:550.64Sulfuretin
CAS:<p>Sulfuretin protects HepG2 cells from oxidative damage by scavenging ROS and activating HO-1 via Nrf2/ARE and JNK/ERK pathways.</p>Formula:C15H10O5Purezza:98.91% - 99.86%Colore e forma:SolidPeso molecolare:270.24Pyrrolidinedithiocarbamate ammonium
CAS:Pyrrolidinedithiocarbamate ammonium (1-Pyrrolidinedithiocarboxylic acid ammonium salt), a selective NF-κB inhibitor, inhibits translation of nitric oxideFormula:C5H12N2S2Purezza:98% - >99.99%Colore e forma:Off-White To Pale Yellow CrystalsPeso molecolare:164.29Ethacrynic acid
CAS:<p>Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂，也是NF-κB 信号传导途径的有效抑制剂，并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道，从而导致气道平滑肌细胞松弛。它是利尿剂，具有抗炎特性，可减轻类维生素 A 诱导的小鼠耳部水肿。</p>Formula:C13H12Cl2O4Purezza:98.61% - 99.85%Colore e forma:Crystals Physical Description White Solid (Ntp 1992)Peso molecolare:303.14Flaconitine
CAS:<p>Flaconitine (Acetylaconitine) is an NF-κB inhibitor and an alkaloid.</p>Formula:C36H49NO12Purezza:98% - 99.84%Colore e forma:SolidPeso molecolare:687.77Vanillic Acid
CAS:<p>Vanillic Acid (Acide vanillique) is used as a condiment in food, which used in wine. It is an intermediate in the production of vanillin from ferulic acid.</p>Formula:C8H8O4Purezza:99.82%Colore e forma:White Odourless Crystals Or PowderPeso molecolare:168.152-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC
CAS:<p>2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC is Inhibitior of IKKβ.</p>Formula:C11H10N2OSPurezza:99.48%Colore e forma:SolidPeso molecolare:218.27BOT-64
CAS:<p>BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathiole</p>Formula:C15H15NO2SPurezza:99.73%Colore e forma:SolidPeso molecolare:273.3518α-Glycyrrhetinic acid
CAS:<p>18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.</p>Formula:C30H46O4Purezza:98.54% - 99.68%Colore e forma:SolidPeso molecolare:470.68(E/Z)-IT-603
CAS:<p>(E/Z)-IT-603 is a cell-permeable c-Rel inhibitor. IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding activity.</p>Formula:C11H9BrN2O3SPurezza:99.35%Colore e forma:SolidPeso molecolare:329.17MLN120B
CAS:<p>MLN120B is a selective and ATP competitive IKKβ inhibitor (IC50: 60 nM).</p>Formula:C19H15ClN4O2Purezza:98.92%Colore e forma:SolidPeso molecolare:366.8Asperulosidic acid
CAS:<p>Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines.</p>Formula:C18H24O12Purezza:99.47%Colore e forma:SolidPeso molecolare:432.38BX795
CAS:<p>BX795 selectively inhibits PDK1 (IC50: 6 nM), 140x over PKA, 1600x over PKC, 100x over GSK3β in cell-free assays.</p>Formula:C23H26IN7O2SPurezza:98% - 99.57%Colore e forma:SolidPeso molecolare:591.47ISOGINKGETIN
CAS:<p>ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.</p>Formula:C32H22O10Purezza:98% - 99.72%Colore e forma:SolidPeso molecolare:566.51PTP1B-IN-1
CAS:<p>PTP1B-IN-1 (PTP1B inhibitor) is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM)</p>Formula:C8H8N2O3SPurezza:99.27%Colore e forma:SolidPeso molecolare:212.23Galloylpaeoniflorin
CAS:<p>Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress.</p>Formula:C30H32O15Purezza:99.82%Colore e forma:SolidPeso molecolare:632.57AZD3264
CAS:<p>AZD3264 is a new type IKK2 inhibitor.</p>Formula:C21H23N5O4SPurezza:98.98% - 99.17%Colore e forma:SolidPeso molecolare:441.5IRAK4-IN-7
CAS:<p>IRAK4-IN-7 (CA-4948) is a selective and potent IRAK4 kinase inhibitor with in vivo activity in a TLR4-induced cytokine release model.</p>Formula:C21H19N7O3Purezza:99.5%Colore e forma:SolidPeso molecolare:417.42Iron sucrose
CAS:<p>Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia.</p>Formula:C18H24Fe2O24Purezza:99.97%Colore e forma:SolidPeso molecolare:736.1yangonin
CAS:<p>Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.</p>Formula:C15H14O4Purezza:98.82% - 99.55%Colore e forma:Pale Yellow PowderPeso molecolare:258.27Cyclo(his-pro)
CAS:<p>Cyclo(his-pro) is a cyclic dipeptide that shields against oxidative damage by activating Nrf2.</p>Formula:C11H14N4O2Purezza:99.87%Colore e forma:SolidPeso molecolare:234.25Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Formula:C40H52O4Purezza:95.1% - 99.79%Colore e forma:Needles From Acetone/Light Petroleum SolidPeso molecolare:596.847,4'-Dihydroxyflavone
CAS:<p>7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.</p>Formula:C15H10O4Purezza:99.39% - 99.6%Colore e forma:SolidPeso molecolare:254.24Rucaparib
CAS:<p>Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.</p>Formula:C19H18FN3OPurezza:98.24% - 99.80%Colore e forma:SolidPeso molecolare:323.36GSK8612
CAS:<p>GSK8612 is a highly selective and potent inhibitor of Tank-binding Kinase-1 (TBK1, pIC50: 6.8) .</p>Formula:C17H17BrF3N7O2SPurezza:99.46% - 99.8%Colore e forma:SolidPeso molecolare:520.33Avicularin
CAS:<p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>Formula:C20H18O11Purezza:97.02% - 99.94%Colore e forma:White PowderPeso molecolare:434.35Sodium Aescinate
CAS:<p>Sodium Aescinate (Escin sodium salt) is extracted from Aesculus wilsonii.</p>Formula:C54H83NaO23Purezza:95.17%Colore e forma:SolidPeso molecolare:1123.21Berbamine
CAS:<p>Berbamine is a natural product extracted from Phellodendron amurense.</p>Formula:C37H40N2O6Purezza:98.92% - 99.67%Colore e forma:White Crystal PowderPeso molecolare:608.72Ginsenoside Rb3
CAS:<p>Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity.</p>Formula:C53H90O22Purezza:98% - 99.98%Colore e forma:SolidPeso molecolare:1079.27Chelidonic acid
CAS:<p>Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.</p>Formula:C7H4O6Purezza:99.03%Colore e forma:SolidPeso molecolare:184.1Licochalcone D
CAS:<p>Licochalcone D may treat melanoma and heart injury, halt cell spread, and reduce inflammation and allergies.</p>Formula:C21H22O5Purezza:99.03% - 99.9%Colore e forma:SolidPeso molecolare:354.4Muscone
CAS:<p>Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.</p>Formula:C16H30OPurezza:98.97% - ≥98%Colore e forma:Colourless Liquid LiquidPeso molecolare:238.41Eclitasertib
CAS:<p>Eclitasertib is a potent inhibitor of receptor-interacting protein kinase 1 (RIPK1, IC50 of <1 µΜ).</p>Formula:C19H18N6O3Purezza:99.85%Colore e forma:SolidPeso molecolare:378.38Specnuezhenide
CAS:<p>Specnuezhenide (Nuezhenide) is isolated from the fruit of Ligustrum lucidum. It inhibits NF-κB and wnt/β-catenin signaling.Cost-effective and quality-assured.</p>Formula:C31H42O17Purezza:98% - 99.93%Colore e forma:SolidPeso molecolare:686.66Isoquercetin
CAS:<p>1.</p>Formula:C21H20O12Purezza:98.08% - 99.76%Colore e forma:SolidPeso molecolare:464.38WITHAFERIN A
CAS:<p>WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/</p>Formula:C28H38O6Purezza:97.41% - 99.99%Colore e forma:SolidPeso molecolare:470.6Ginsenoside Rd
CAS:<p>Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.</p>Formula:C48H82O18Purezza:99.13% - 99.92%Colore e forma:SolidPeso molecolare:947.15Dehydroevodiamine
CAS:<p>Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant</p>Formula:C19H15N3OPurezza:99.54%Colore e forma:SolidPeso molecolare:301.34Dauricine
CAS:<p>1.</p>Formula:C38H44N2O6Purezza:99.24% - 99.75%Colore e forma:White PowderPeso molecolare:624.77Dendrophenol
CAS:<p>Dendrophenol (Moscatilin) is a natural product isolated from the stem of Dendrobium loddigesii Rolfe, act as a NF-κB inhibitor. Antineoplastic activity.</p>Formula:C17H20O5Purezza:98.2% - 99.36%Colore e forma:SolidPeso molecolare:304.34Tizoxanide
CAS:Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.Formula:C10H7N3O4SPurezza:98.89% - 99.28%Colore e forma:SolidPeso molecolare:265.25Diethylmaleate
CAS:<p>Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.</p>Formula:C8H12O4Purezza:98%Colore e forma:Colourless LiquidPeso molecolare:172.18SC-514
CAS:<p>SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 μM), obstructs NF-κB-dependent gene expression.</p>Formula:C9H8N2OS2Purezza:99.88% - >99.99%Colore e forma:SolidPeso molecolare:224.3Ac2-26 acetate
<p>Ac2-26 acetate is an active N-terminal peptide of annexin A1(AnxA1).</p>Formula:C141H210N32O44SPurezza:98%Colore e forma:SolidPeso molecolare:3089.43IRAK inhibitor 6
CAS:<p>IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4, IC50: 160 nM).</p>Formula:C20H20N4O3SPurezza:99.44%Colore e forma:SolidPeso molecolare:396.462-Hydroxychalcone
CAS:<p>2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.</p>Formula:C15H12O2Purezza:99.6%Colore e forma:SolidPeso molecolare:224.25Neochlorogenic acid
CAS:<p>Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.</p>Formula:C16H18O9Purezza:99.12% - 99.54%Colore e forma:White PowderPeso molecolare:354.31Triacetylresveratrol
CAS:<p>Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.</p>Formula:C20H18O6Purezza:99.81%Colore e forma:Off White PowderPeso molecolare:354.35AS-2444697
CAS:<p>AS-2444697, an IRAK-4 inhibitor (C50=21 nM), offers renal protection via anti-inflammatory effects on human and rat IRAK-4.</p>Formula:C19H21ClN6O4Purezza:97.17%Colore e forma:SolidPeso molecolare:432.862,5-Dihydroxyacetophenone
CAS:<p>2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.</p>Formula:C8H8O3Purezza:99.75%Colore e forma:Yellow PowderPeso molecolare:152.15Phellodendrine
CAS:<p>Phellodendrine may treat nephritis by blocking macrophage and T cell activity in glomeruli.</p>Formula:C20H24NO4Purezza:98.7% - 99.94%Colore e forma:SolidPeso molecolare:342.41Micheliolide
CAS:<p>Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.</p>Formula:C15H20O3Purezza:98% - 99.37%Colore e forma:SolidPeso molecolare:248.32Isovitexin
CAS:<p>1.</p>Formula:C21H20O10Purezza:99.79% - 99.97%Colore e forma:SolidPeso molecolare:432.38
