ROS

Moracin C and D, new phytoalexins from diseased mulberry, are antifungal compounds.

Procyanidin C1 is a natural product, with anti-inflammatory effects, and induces apoptosis.

Plumbagin is a yellow dye, formally derived from naphthoquinone. It is named after the plant …

Emeramide is a thiol-redox antioxidant. It is also a heavy metal chelator.

Oxipurinol is a xanthine oxidase inhibitor. Oxipurinol is potentially used for the treatment of congestive …

Secoisolariciresinol Diglucoside was cytoprotective in an in vitro model of iron overload-induced redox-inflammatory damage. Secoisolariciresinol …

Blumeatin has antioxidant properties, free radical scavenging activity,and has xanthine oxidase (XO) inhibitory activity.

Allopurinol is a Xanthine Oxidase Inhibitor. The mechanism of action of allopurinol is as a …

Dihydrotanshinone I is a natural compound extracted from Salvia miltiorrhiza Bunge used for treating of …

Mitoquinone mesylate is a TPP-based, mitochondrially targeted antioxidant to protect against oxidative damage.

N-Acetylcysteine amide is a cell membranes and blood brain barrier permeant thiol antioxidant and neuroprotective …

Acetylcysteine is the N-acetyl derivative of CYSTEINE. It is used as a mucolytic agent to …

Berberine chloride hydrate (Natural Yellow 18 chloride hydrate) is an alkaloid isolated from the Chinese …

Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 …

WY-135 is a dual inhibitor of ALK and ROS1 (IC50 of 1.4 nM and 1.1 …

Piperlongumine is a natural alkaloid from Piper longum L. It selectively kills cancer cells and …

AlbA-DCA is a conjugate formed by the attachment of Albiziabioside A to a dichloroacetate acid …

Camalexin is a phytoalexin isolated from Camelina sativa. It has antifungal, antibacterial, antiproliferative, and anticancer …

Cyclocurcumin, a curcumin derivative, exhibits anticancer, anti-inflammatory, and immune-modulating abilities and is a potential compound …

Alpha-Amyrin is trypsin and chymotrypsin inhibitor,it has antineoplastic,it induces proliferation of human keratinocytes.Alpha-Amyrin can as …

Malvidin chloride has anti-spermatogenic, and antioxidant activities. It can prevent endothelial dysfunction by inhibiting ROS …

Carnosic acid is a lipid absorption inhibitor, endowed with antioxidative, antimicrobial, photoprotective potential, and antiproliferative …

Inosine is a purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the …

Delphinidin-3-sambubioside chloride has antioxidant activity.

Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through …

Brandioside shows strong antioxidant, and neuroprotective effects, it significantly attenuates glutamate-induced neurotoxicity at concentrations ranging …

Oleuropein is an antioxidant polyphenol isolated from olive leaf.

Bacoside A3 is one of the components of Bacopa monnieri (L.) Wettst. bacoside A with …

Futoquinol is an anti-platelet activating factor principle from the stem part of Piper futokadsura (Piperaceae), …

Matairesinol has radical and superoxide scavenging activities,; it also has anti-angiogenic activity by suppressing mROS …

Sugiol has antioxidant efficacy, it has significant scavenging activities of 1,1-diphenyl-2-picryl hydrazyl, nitric oxide, superoxide …

CIL56 is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive …

(+)-1-Hydroxypinoresinol 1-O-beta-D-glucoside exhibits peroxynitrite, total ROS and DPPH radical scavenging activities with IC50 values of …

DMNQ is a 1,4-naphthoquinone that acts as a redox-cycling agent, typically increasing intracellular superoxide and …

Medicarpin, a legume phytoalexin, acts as an estrogen receptor (ER) agonist, can stimulate osteoblast differentiation …

Hederacolchiside E has antioxidant activity, it shows inhibition on lipid peroxidation of linoleic acid emulsion; …

Diosbulbin D shows direct toxic effect on hepatocytes, the mechanism could be associated with oxidative …

Isodeoxyelephantopin can inhibit the growth of various tumor cells.

Pyrroside B shows stronger antioxidative activity than that of α-tocopherol.

Kushenol W is a natural product

Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a …

Lycopene is a linear, unsaturated hydrocarbon carotenoid, the major red pigment in fruits such as …

Tiopronin, a sulfhydryl acylated derivative of glycine, leads to a reduction in urinary cystine concentration …

1, 2-Dihydro-4-methoxy-2-oxo-3-pyridinecarbonitrile was reported as xanthine oxidase inhibitor.

Gallic acid is found in almost all plants. Plants known for their high gallic acid …

Tempol is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.

Topiroxostat is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and …

Febuxostat is a xanthine oxidase Inhibitor.

Baicalein is a xanthine oxidase inhibitor.

Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.

Martynoside is a natural selective estrogen receptor modulator, which has antioxidative, anti-muscle fatigue, anticancer and …

Carminic acid, the well-known red dyestuff from cochineal insects (Dactylopius spp.), is a potent feeding …

7,3',4'-Trihydroxy-3-benzyl-2H-chromene is a potential xanthine oxidase inhibitor.

1,5,6-Trihydroxy-3-methoxyxanthone exhibits scavenging activity at 10 uM, it can reduce the viability of HL-60 cells …

5-Galloylquinic acid as an index for the baking intensity of oolong teas. It has antioxidant …

Pyrazoloadenine is the inhibitor of human xanthine oxidase.

Medioresinol possesses antioxidative, a lesishmanicidal activity and cardiovascular disease risk reduction, it has antiamyloidogenic activity …

Ophiopogonin D(OPD) significantly inhibited the in vitro and in vivo growth of prostate cells via …

Galloylpaeoniflorin may be developed as a cytoprotector against ROS-mediated oxidative stress. Galloylpaeoniflorin is also an …

(±)-Catechin hydrate is a natural product,has antioxidant activity and is effective in reducing oxidative stress.

HO-1-IN-1 is a heme oxygenase 1 (HO-1) inhibitor (IC50: 250 nM).

3, 8''-Biapigenin can modulate intracellular ROS production.

8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,

DS-6051b is a new-generation selective inhibitor of ROS1/NTRK including ROS1,NTRK1,NTRK2 and NTRK3 with IC50 of …

Daidzin 6''-O-malonate may have anticancer activity.

Tofogliflozin hydrate is a potent and highly specific inhibitor of SGLT2(IC50 of 2.9 nM and …