Canale TRP/TRPV
canali TRP (Transient Receptor Potential), inclusa la sottofamiglia TRPV, sono un gruppo di canali ionici coinvolti in vari processi sensoriali, come la percezione della temperatura, la sensazione del dolore e l'osmoregolazione. I canali TRP sono ampiamente espressi in diversi tessuti e svolgono un ruolo nelle risposte fisiologiche agli stimoli ambientali. In particolare, i canali TRPV sono coinvolti nel rilevamento dei cambiamenti di temperatura e sono implicati in condizioni come il dolore cronico, l'infiammazione e il cancro. Presso CymitQuimica, offriamo una gamma completa di modulatori dei canali TRP/TRPV per supportare la tua ricerca in biologia sensoriale, gestione del dolore e trasduzione del segnale.
Trovati 96 prodotti di "Canale TRP/TRPV"
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BI-749327
CAS:BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6).Formula:C23H21F3N4O2Purezza:99.68% - 99.84%Colore e forma:SolidPeso molecolare:442.43Ref: TM-T10537
1mg133,00€2mg177,00€5mg274,00€10mg432,00€25mg630,00€50mg825,00€100mg1.103,00€500mg2.205,00€1mL*10mM (DMSO)301,00€TRPV4 agonist-1 free base
CAS:TRPV4 agonist-1 free base (OUN67600) is an agonist of transient receptor potential vanilloid 4 (TRPV4;EC50 of 60 nM, in the hTRPV4 Ca2+ assay).Formula:C25H22F2N4O2Purezza:99.79%Colore e forma:SolidPeso molecolare:448.46GFB-8438
CAS:GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively).Formula:C16H14ClF3N4O2Purezza:99.58%Colore e forma:SolidPeso molecolare:386.76Ref: TM-T11394
2mg35,00€5mg52,00€10mg81,00€25mg117,00€50mg170,00€100mg250,00€200mg369,00€1mL*10mM (DMSO)58,00€IA-Alkyne
CAS:IA-Alkyne: TRPC agonist, cysteine-reactivity probe, potential in respiratory infection study.Formula:C8H12INOPurezza:99.76%Colore e forma:SolidPeso molecolare:265.09Ref: TM-T15543
1mg59,00€5mg126,00€10mg187,00€25mg264,00€50mg329,00€100mg455,00€1mL*10mM (DMSO)120,00€(Z)-Capsaicin
CAS:<p>(Z)-Capsaicin (Zucapsaicin) is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.(Z)-Capsaicin is a synthetic cis isomer of</p>Formula:C18H27NO3Purezza:97.33% - 98.91%Colore e forma:SolidPeso molecolare:305.41Vocacapsaicin hydrochloride
CAS:<p>Vocacapsaicin hydrochloride (CA-008 hydrochloride) is a non-opioid TRPV1 agonist, a raw material for capsaicin, and is used for pain relief.</p>Formula:C26H42ClN3O4Purezza:99.66% - 99.80%Colore e forma:SolidPeso molecolare:496.08AP 18
CAS:<p>AP-18 is a potent and selective TRPA1 inhibitor.</p>Formula:C11H12ClNOPurezza:99.85% - 99.96%Colore e forma:SolidPeso molecolare:209.67CBP-1008
CBP-1008 is a dual-ligand peptide-drug conjugate (PDC) with MMAE, targeting folate receptor (FRα) and TRPV6. It exhibits high binding affinity to FRα and low affinity to TRPV6. CBP-1008 shows antitumor activity and can be utilized for research in advanced solid tumors such as colorectal cancer, breast cancer, non-small cell lung cancer, ovarian cancer, adrenocortical carcinoma, and follicular dendritic cell sarcoma.Colore e forma:Odour SolidN-Oleoyl Valine Ammonium salt
N-Oleoyl Valine Ammonium salt is an N-acyl amide compound that is a TRPV3 antagonist and can be used to study inflammation.Formula:C23H46N2O3Purezza:99.72%Colore e forma:SolidPeso molecolare:398.62RN-1665
CAS:RN-1665 is a potent and selective TRPV4 receptor antagonist.Formula:C20H24F5N3O3S2Purezza:99.96%Colore e forma:SoildPeso molecolare:513.54(S)-ABT 102
CAS:N-[(1S)-1H-inden-1-yl]-N'-indazol-4-ylurea is a strong TRPV1 blocker with a 123 nM IC50 against capsaicin.Formula:C21H24N4OPurezza:99.65% - 99.77%Colore e forma:SoildPeso molecolare:348.44Ref: TM-T29522L
1mg73,00€5mg149,00€10mg212,00€25mg319,00€50mg447,00€100mg610,00€200mg822,00€1mL*10mM (DMSO)154,00€TRPM8 antagonist 3
CAS:TRPM8 antagonist 3 is a blocker of TRPM8 (IC50 = 11 nM).Formula:C13H12N2O4SPurezza:99.74%Colore e forma:SolidPeso molecolare:292.31PF-04745637
CAS:PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].Formula:C27H32ClF3N2O2Purezza:98.88% - 99.3%Colore e forma:SolidPeso molecolare:509Ref: TM-T64337
1mg73,00€5mg145,00€10mg197,00€25mg333,00€50mg475,00€100mg655,00€200mg882,00€1mL*10mM (DMSO)163,00€TRPA1-IN-2
CAS:TRPA1-IN-2 is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM.TRPA1-IN-2 has anti-inflammatory activity.Formula:C24H25F3N4OPurezza:98.93%Colore e forma:SoildPeso molecolare:442.48Ref: TM-T77511
1mg56,00€5mg129,00€10mg188,00€25mg319,00€50mg447,00€100mg600,00€200mg807,00€1mL*10mM (DMSO)142,00€Resolvin D2
CAS:Resolvin D2 (RvD2) is a TRPV1 inhibitor and pro-ablative mediator with anti-inflammatory, anti-infective and pro-ablative effects.Formula:C22H32O5Purezza:98%Colore e forma:SolidPeso molecolare:376.49Cyclic ADP-Ribose (ammonium salt)
Cyclic ADP-Ribose (ammonium salt) (cADPR) is an NAD⁺ metabolite that triggers Ca²⁺ release from ER stores via ryanodine receptors, relevant to inflammation research.Formula:C15H21N5O13P2·xNH3Colore e forma:SolidOleoyl Serotonin
CAS:<p>Oleoyl Serotonin is an antagonist of hTRPV1 with an IC50 of 2.57 μM.</p>Formula:C28H44N2O2Purezza:99.88%Colore e forma:SolidPeso molecolare:440.66L-R4W2
CAS:Vanilloid TRPV1 (VR1) receptor antagonist peptide (IC50 ~ 0.1 μM); blocks Ca2+ currents in dorsal root ganglion neurons. Analgesic in vivo.Formula:C46H71N21O6Purezza:98%Colore e forma:SolidPeso molecolare:1014.2NGD-8243
CAS:NGD-8243 (N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)pyridin-2-yl]quinazolin-4-amine) is a TRPV1 inhibitor and can be used in studies for preventionFormula:C21H12F6N4Purezza:95.26%Colore e forma:SolidPeso molecolare:434.34Ref: TM-T9818
1mg185,00€5mg415,00€10mg613,00€25mg938,00€50mg1.311,00€1mL*10mM (DMSO)Prezzo su richiestaGSK2798745
CAS:GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: 1.8 and 1.6 nM for hTRPV4 and rTRPV4).Formula:C25H28N6O3Colore e forma:SolidPeso molecolare:460.53
