Canale TRP/TRPV
canali TRP (Transient Receptor Potential), inclusa la sottofamiglia TRPV, sono un gruppo di canali ionici coinvolti in vari processi sensoriali, come la percezione della temperatura, la sensazione del dolore e l'osmoregolazione. I canali TRP sono ampiamente espressi in diversi tessuti e svolgono un ruolo nelle risposte fisiologiche agli stimoli ambientali. In particolare, i canali TRPV sono coinvolti nel rilevamento dei cambiamenti di temperatura e sono implicati in condizioni come il dolore cronico, l'infiammazione e il cancro. Presso CymitQuimica, offriamo una gamma completa di modulatori dei canali TRP/TRPV per supportare la tua ricerca in biologia sensoriale, gestione del dolore e trasduzione del segnale.
Trovati 93 prodotti di "Canale TRP/TRPV"
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(Z)-Capsaicin
CAS:<p>(Z)-Capsaicin (Zucapsaicin) is a medication used to treat osteoarthritis of the knee and Others neuropathic pain.(Z)-Capsaicin is a synthetic cis isomer of</p>Formula:C18H27NO3Purezza:97.33% - 98.91%Colore e forma:SolidPeso molecolare:305.41TRPV4 agonist-1 free base
CAS:<p>TRPV4 agonist-1 free base (OUN67600) is an agonist of transient receptor potential vanilloid 4 (TRPV4;EC50 of 60 nM, in the hTRPV4 Ca2+ assay).</p>Formula:C25H22F2N4O2Purezza:99.79%Colore e forma:SolidPeso molecolare:448.46GFB-8438
CAS:<p>GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively).</p>Formula:C16H14ClF3N4O2Purezza:99.58%Colore e forma:SolidPeso molecolare:386.76BI-749327
CAS:<p>BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6).</p>Formula:C23H21F3N4O2Purezza:99.68%Colore e forma:SolidPeso molecolare:442.43IA-Alkyne
CAS:<p>IA-Alkyne: TRPC agonist, cysteine-reactivity probe, potential in respiratory infection study.</p>Formula:C8H12INOPurezza:99.76%Colore e forma:SolidPeso molecolare:265.09Vocacapsaicin hydrochloride
CAS:<p>Vocacapsaicin hydrochloride (CA-008 hydrochloride) is a non-opioid TRPV1 agonist, a raw material for capsaicin, and is used for pain relief.</p>Formula:C26H42ClN3O4Purezza:99.66% - 99.80%Colore e forma:SolidPeso molecolare:496.08NGD-8243
CAS:<p>NGD-8243 (N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)pyridin-2-yl]quinazolin-4-amine) is a TRPV1 inhibitor and can be used in studies for prevention</p>Formula:C21H12F6N4Purezza:95.26%Colore e forma:SolidPeso molecolare:434.34AP 18
CAS:<p>AP-18 is a potent and selective TRPA1 inhibitor.</p>Formula:C11H12ClNOPurezza:99.85% - 99.96%Colore e forma:SolidPeso molecolare:209.67GSK2798745
CAS:<p>GSK2798745 is an orally active transient receptor potential vanilloid 4 (TRPV4) ion channel blocker (IC50s: 1.8 and 1.6 nM for hTRPV4 and rTRPV4).</p>Formula:C25H28N6O3Colore e forma:SolidPeso molecolare:460.53RN-1665
CAS:<p>RN-1665 is a potent and selective TRPV4 receptor antagonist.</p>Formula:C20H24F5N3O3S2Purezza:>99.99%Colore e forma:SoildPeso molecolare:513.54CBP-1008
<p>CBP-1008 is a dual-ligand peptide-drug conjugate (PDC) with MMAE, targeting folate receptor (FRα) and TRPV6. It exhibits high binding affinity to FRα and low affinity to TRPV6. CBP-1008 shows antitumor activity and can be utilized for research in advanced solid tumors such as colorectal cancer, breast cancer, non-small cell lung cancer, ovarian cancer, adrenocortical carcinoma, and follicular dendritic cell sarcoma.</p>Colore e forma:Odour Solid(S)-ABT 102
CAS:<p>N-[(1S)-1H-inden-1-yl]-N'-indazol-4-ylurea is a strong TRPV1 blocker with a 123 nM IC50 against capsaicin.</p>Formula:C21H24N4OPurezza:99.65% - 99.77%Colore e forma:SoildPeso molecolare:348.44PF-04745637
CAS:<p>PF-04745637 is a potent and selective TRPA1 antagonist with an IC50 of 17 nM[1].</p>Formula:C27H32ClF3N2O2Purezza:98.88% - 99.3%Colore e forma:SolidPeso molecolare:509TRPA1-IN-2
CAS:<p>TRPA1-IN-2 is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM.TRPA1-IN-2 has anti-inflammatory activity.</p>Formula:C24H25F3N4OPurezza:98.05%Colore e forma:SoildPeso molecolare:442.48Resolvin D2
CAS:<p>Resolvin D2 (RvD2) is a TRPV1 inhibitor and pro-ablative mediator with anti-inflammatory, anti-infective and pro-ablative effects.</p>Formula:C22H32O5Purezza:98%Colore e forma:SolidPeso molecolare:376.49TRPM8 antagonist 3
CAS:<p>TRPM8 antagonist 3 is a blocker of TRPM8 (IC50 = 11 nM).</p>Formula:C13H12N2O4SPurezza:99.74%Colore e forma:SolidPeso molecolare:292.31Oleoyl Serotonin
CAS:<p>Oleoyl Serotonin is an antagonist of hTRPV1 with an IC50 of 2.57 μM.</p>Formula:C28H44N2O2Purezza:99.88%Colore e forma:SolidPeso molecolare:440.66L-R4W2
CAS:<p>Vanilloid TRPV1 (VR1) receptor antagonist peptide (IC50 ~ 0.1 μM); blocks Ca2+ currents in dorsal root ganglion neurons. Analgesic in vivo.</p>Formula:C46H71N21O6Purezza:98%Colore e forma:SolidPeso molecolare:1014.2Phenazopyridine
CAS:<p>Phenazopyridine is an orally administered azo dye with local analgesic effects on urinary tract infections,. against SARM1 and TRPM8.</p>Formula:C11H11N5Purezza:99.98%Colore e forma:SolidPeso molecolare:213.24BTD
CAS:<p>BTD is a TRPC5 activator that activates heteromeric channel complexes composed of TRPC5 and its closest relatives TRPC1 or TRPC4.</p>Formula:C24H33N3O4SColore e forma:SolidPeso molecolare:459.6
