PPAR
I recettori attivati dai proliferatori dei perossisomi (PPARs) sono un gruppo di proteine recettori nucleari che funzionano come fattori di trascrizione regolando l'espressione di geni coinvolti nel metabolismo, in particolare lo stoccaggio degli acidi grassi e il metabolismo del glucosio. Gli inibitori dei PPARs sono strumenti importanti per lo studio dei disturbi metabolici come il diabete, l'obesità e le malattie cardiovascolari. Questi inibitori possono modulare il metabolismo dei lipidi, la sensibilità all'insulina e l'infiammazione, rendendoli preziosi nella ricerca terapeutica. Presso CymitQuimica, offriamo una gamma di inibitori dei PPARs per supportare la tua ricerca in malattie metaboliche, endocrinologia e sviluppo di farmaci.
Trovati 164 prodotti di "PPAR"
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GED-0507-34 Levo
CAS:<p>GED-0507-34 Levo,(S)-3-(4-Aminophenyl)-2-methoxypropanoic acid,an orally available PPARγ modulator for amelioration of inflammation-driven intestinal fibrosis.</p>Formula:C10H13NO3Purezza:98.19%Colore e forma:SolidPeso molecolare:195.22Fenofibric acid
CAS:<p>Fenofibric acid (FNF acid) is the active form of fenofibrate, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity.</p>Formula:C17H15ClO4Purezza:99.36%Colore e forma:White Or Almost White Crystalline PowderPeso molecolare:318.75Magnolol
CAS:<p>Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.</p>Formula:C18H18O2Purezza:99.49%Colore e forma:A Bioactive Compound Found In The Bark Of The Houpu MagnoliaPeso molecolare:266.33Clofibric acid
CAS:<p>Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.</p>Formula:C10H11ClO3Purezza:99.47% - 99.8%Colore e forma:Pale Yellow SolidPeso molecolare:214.65NTP42
CAS:<p>NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)</p>Formula:C25H23F2N3O5SPurezza:97.55%Colore e forma:SolidPeso molecolare:515.53LY518674
CAS:<p>LY518674 (LY-674) decreases triglycerides and increases HDL-C and is used for the treatment of atherosclerosis.</p>Formula:C23H27N3O4Purezza:98.87%Colore e forma:SolidPeso molecolare:409.48Daidzein
CAS:<p>Daidzein (Isoflavone) is an isoflavone extract from soy, which is an inactive analog of the tyrosine kinase inhibitor genistein.</p>Formula:C15H10O4Purezza:98.08%Colore e forma:SolidPeso molecolare:254.24EHP-101
CAS:<p>EHP-101 is a PPARγ/CB2 dual agonist with anti-inflammatory properties, inhibits fat formation, and combats diet-related obesity.</p>Formula:C28H35NO3Purezza:98.36%Colore e forma:SolidPeso molecolare:433.58Retinoic acid
CAS:<p>Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.</p>Formula:C20H28O2Purezza:97.21% - 99.6%Colore e forma:Yellow-Orange PowderPeso molecolare:300.44MK-0533
CAS:<p>MK-0533 is a novel PPARγ partial agonist for the prevention of vascular endothelial dysfunction (VED) and VED-related cardiovascular disease.</p>Formula:C28H24F3NO6Purezza:99.03%Colore e forma:SoildPeso molecolare:527.49MA-0204
CAS:<p>MA-0204 is a highly selective and orally available peroxisome proliferator-activated receptor δ (PPARδ) modulator (EC50s: 0.4 nM, 7.9 nM and 10 nM for human,</p>Formula:C25H27F3N2O4Purezza:97.8%Colore e forma:SolidPeso molecolare:476.49NSC-87877
CAS:<p>NSC-87877 inhibits Shp2 (IC50=0.318μM), Shp1 (IC50=0.355μM), and DUSP26 phosphatases.</p>Formula:C19H13N3O7S2Purezza:97.35%Colore e forma:SolidPeso molecolare:459.45Arhalofenate
CAS:<p>Arhalofenate (JNJ 39659100) is a selective partial agonist of peroxisome proliferator-activated receptor PPARγ. It is used for the treatment of type 2 diabetes.</p>Formula:C19H17ClF3NO4Purezza:98.97%Colore e forma:SolidPeso molecolare:415.79Candesartan
CAS:<p>Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.</p>Formula:C24H20N6O3Purezza:98.3% - 99.55%Colore e forma:Colorless Solid CrystallinePeso molecolare:440.47Pioglitazone hydrochloride
CAS:<p>Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic</p>Formula:C19H20N2O3S·HClPurezza:99.64% - >99.99%Colore e forma:White Crystals Or Crystalline PowderPeso molecolare:392.90Anandamide
CAS:<p>Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but also</p>Formula:C22H37NO2Purezza:95.037% - 99.22%Colore e forma:Light Yellow OilPeso molecolare:347.53Muraglitazar
CAS:<p>Muraglitazar (BMS-298585) is a PPAR α/γ dual agonist for the treatment of type 2 diabetes and associated dyslipidemia.</p>Formula:C29H28N2O7Purezza:99.17%Colore e forma:SolidPeso molecolare:516.54Oleoylethanolamide
CAS:<p>Oleoylethanolamide (N-Oleoylethanolamide) is a high affinity endogenous agonist of PPAR-α.</p>Formula:C20H39NO2Purezza:99.98%Colore e forma:SolidPeso molecolare:325.53Mifobate
CAS:<p>Mifobate (SR-202) 是一种有效且特异性的 PPARγ拮抗剂，可选择性抑制噻唑烷二酮 (TZD) 诱导的 PPARγ 转录活性，IC50为140 μM，具有抗肥胖和抗糖尿病作用。</p>Formula:C11H17ClO7P2Purezza:99.12%Colore e forma:SolidPeso molecolare:358.65Pioglitazone
CAS:<p>Pioglitazone (U 72107) is a selective and oral PPARγ agonist with EC50 of 0.93 and 0.99 μM on human and mouse PPARγ, respectively . High-Quality, Low-Cost!</p>Formula:C19H20N2O3SPurezza:95% - 99.57%Colore e forma:White PowderPeso molecolare:356.44
