PPAR

Ankaflavin is isolated from Monascus-Fermented red rice and is a PPARγ agonist with anti-inflammatory activity. …

XMD16-5 is a TNK2 inhibitor. TNK2 genomic amplification has been associated with late-stage or metastatic …

Aleglitazar is being developed for the treatment of type II diabetes; It is currently in …

LY518674 decreases triglycerides and increases HDL-C and is used for the treatment of atherosclerosis. LY518674 …

Indeglitazar is orally available pan-agonist of PPAR (PPAR subtypes alpha (α), delta (δ), and gamma …

Lanifibranor is an agonist of peroxisome proliferator-activated receptors (PPARs) with EC50 values of 1,537, 866, …

PPARα-MO-1 is a potent modulator of PPARα extracted from patent WO/2004/110982A1 (formula I).

Fonadelpar is an agonist of PPARδ. It also is used in the research of neuroparalytic …

Troglitazone is a PPARγ agonist with anti-inflammatory and anti-tumor activity.

XMD8-87 is a TNK2 inhibitor with activity in the inhibition of TNK2 phosphorylation. XMD8-87 and …

NVP-TNKS656 is a highly potent, selective, and orally active TNKS2 inhibitor.

MA-0204 is a highly selective and orally available peroxisome proliferator-activated receptor δ (PPARδ) modulator (EC50s: …

PPARδ agonist is an agonist of PPARδ.

Extracted from whole herb of Gynostemsma pentaphyllum(Thunb.)Mak.;Store the product in sealed, cool and dry condition

Growth hormone releasing peptide ia a natual product ,and has anti-inflammatory effects, due to its …

Bavachinin(7-O-Methylbavachin) is a natural compound isolated from the Chinese herb Fructus Psoraleae with potent anti-angiogenic …

L-165041 is a potent and selective agonist of the nuclear receptor PPARβ and PPARδ(Ki = …

Inolitazone dihydrochloride is a novel high-affinity agonist of PPARγ. It is dependent upon PPARγ for …

Sakuranetin, a flavanone phytoalexin from ultraviolet-irradiated rice leaves, it has antifungal, antimutagenic, anti-inflammatory and antioxidant …

Fucosterol is isolated from E. stolonifera with anti-diabetic, anti-adipogenic and anti-cancer activities. It regulates adipogenesis …

4'-Methoxychalcone with a variety of pharmacological activities, such as anti-tumor and anti-inflammatory activities.

Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL …

Inolitazone a novel high-affinity agonist of PPARγ. It is dependent upon PPARγ for its biological …

WIKI4 is a potent inhibitor of Wnt/β-catenin signaling and tankyrase 2 (TNKS2).

Chiglitazar is a dual agonist of PPARα/γ (EC50s: 1.2, 0.08, and 1.7 μM for PPARα, …

Arhalofenate is a selective partial agonist of peroxisome proliferator-activated receptor PPARγ. It is used for …

AZ6102 is a potent TNKS1/2 inhibitor that has 100-fold selectivity against other PARP family enzymes …

Tetramethylkaempferol is a PPARγ agonist, it can improve insulin sensitivity by increasing the levels of …

LG100754 is an insulin sensitizer that functions through RXR. LG100754 is an RXR dimer modulator. …

Pioglitazone is an insulin sensitizing agent and thiazolidinedione that is indicated for the treatment of …

Seratrodast (INN), a thromboxane A2 (TXA2) receptor (TP receptor) antagonist, is mainly used in the …

Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.

BMS-687453 is a potent and selective PPAR alpha agonist, with an EC(50) of 10 nM …

Pioglitazone Hydrochloride is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential …

Imiglitazar is a potent and dual human PPARα and PPARγ1 agonist (EC50: 67 and 31 …

AVE-8134 is an agonist of PPARα. For human and rodent PPARα receptor, the EC50 values …

Mifobate is a potent and specific antagonist of PPARγ. Mifobate shows antiobesity, antidiabetic and antiatherosclerotic …

Protopanaxatriol, a major ginseng constituent, is a novel PPARγ antagonist.

Phytol, a diterpene alcohol from chlorophyll widely used as a food additive and in medicinal …

Pirinixic Acid is a synthetic thiacetic acid derivative used in biomedical research, carcinogenic Pirinixic acid …

13-Oxo-9E,11E-octadecadienoic acid, an isomer of 9-oxo-ODA, is a potent PPARα activator derived from tomato juice. …

Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited …

LB-100 is a water soluble protein phosphatase 2A (PP2A) inhibitor. Phase 1.

Ficusin has antioxidant, antilipidemic and antidiabetic effects, it can lower the levels of fasting blood …

Elafibranor is an agonist of the peroxisome proliferator-activated receptor-α (PPAR-α) and peroxisome proliferator-activated receptor-δ (PPAR-δ) …

GW1929 is a potent PPAR-γ agonist (pKi: 8.84 for human PPAR-γ; pEC50s of 8.56 and …

Tesaglitazar causes interstitial mesenchymal cell DNA synthesis and fibrosarcomas in subcutaneous tissues in rats. Tesaglitazar …

Pemafibrate is a highly specific PPARα agonist (EC50: 1 nM).

GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for …

GW7647 is a potent agonist of PPARα (EC50s: 6 nM, 1.1 μM, and 6.2 μM …

RG-12525 is a PPAR-gamma agonist (IC50: appr 60 nM) and a potent inhibitor of CYP3A4 …

GSK376501A is a selective modulator of peroxisome proliferator-activated receptor gamma (PPARγ). It is used for …

Pparδ agonist 2 is an agonist of PPARδ.

NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)

Gentianine has anti-diabetic, antipsychotic, anti-inflammatory, hypotensive, and diuretic actions, it could be developed as a …

LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, …

Uvaol has anti-inflammatory, anti-proliferative, and vasorelaxing activities.

Soyasaponin Aa and soyasaponin Ab dose-dependently markedly inhibit adipocyte differentiation and expression of various adipogenic …

Astaxanthin is a keto-carotenoid in the terpenes class of chemical compounds. It is classified as …

GSK3787 is a specific and irreversible PPARδ inhibitor(pIC50= 6.6).