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PPAR

PPAR

I recettori attivati dai proliferatori dei perossisomi (PPARs) sono un gruppo di proteine recettori nucleari che funzionano come fattori di trascrizione regolando l'espressione di geni coinvolti nel metabolismo, in particolare lo stoccaggio degli acidi grassi e il metabolismo del glucosio. Gli inibitori dei PPARs sono strumenti importanti per lo studio dei disturbi metabolici come il diabete, l'obesità e le malattie cardiovascolari. Questi inibitori possono modulare il metabolismo dei lipidi, la sensibilità all'insulina e l'infiammazione, rendendoli preziosi nella ricerca terapeutica. Presso CymitQuimica, offriamo una gamma di inibitori dei PPARs per supportare la tua ricerca in malattie metaboliche, endocrinologia e sviluppo di farmaci.

Trovati 164 prodotti di "PPAR"

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  • Cloxiquine

    CAS:
    <p>Cloxiquine (Dermofongin) is a monohalogenated 8-hydroxyquinoline with activity against bacteria, fungi, and protozoa.</p>
    Formula:C9H6ClNO
    Purezza:99.82% - 99.87%
    Colore e forma:Light Yellow Crystals
    Peso molecolare:179.6
  • MA-0204

    CAS:
    <p>MA-0204 is a highly selective and orally available peroxisome proliferator-activated receptor δ (PPARδ) modulator (EC50s: 0.4 nM, 7.9 nM and 10 nM for human,</p>
    Formula:C25H27F3N2O4
    Purezza:97.8%
    Colore e forma:Solid
    Peso molecolare:476.49
  • Candesartan

    CAS:
    <p>Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.</p>
    Formula:C24H20N6O3
    Purezza:98.3% - 99.55%
    Colore e forma:Colorless Solid Crystalline
    Peso molecolare:440.47
  • Retinoic acid

    CAS:
    <p>Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.</p>
    Formula:C20H28O2
    Purezza:97.21% - 99.6%
    Colore e forma:Yellow-Orange Powder
    Peso molecolare:300.44
  • Clofibric acid

    CAS:
    <p>Clofibric acid (Chlorofibrinic acid) is an antilipemic agent that is the biologically active metabolite of CLOFIBRATE.</p>
    Formula:C10H11ClO3
    Purezza:99.47% - 99.8%
    Colore e forma:Pale Yellow Solid
    Peso molecolare:214.65
  • GED-0507-34 Levo

    CAS:
    <p>GED-0507-34 Levo,(S)-3-(4-Aminophenyl)-2-methoxypropanoic acid,an orally available PPARγ modulator for amelioration of inflammation-driven intestinal fibrosis.</p>
    Formula:C10H13NO3
    Purezza:98.19%
    Colore e forma:Solid
    Peso molecolare:195.22
  • Fenofibric acid

    CAS:
    <p>Fenofibric acid (FNF acid) is the active form of fenofibrate, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity.</p>
    Formula:C17H15ClO4
    Purezza:99.36%
    Colore e forma:White Or Almost White Crystalline Powder
    Peso molecolare:318.75
  • NSC-87877

    CAS:
    <p>NSC-87877 inhibits Shp2 (IC50=0.318μM), Shp1 (IC50=0.355μM), and DUSP26 phosphatases.</p>
    Formula:C19H13N3O7S2
    Purezza:97.35%
    Colore e forma:Solid
    Peso molecolare:459.45
  • Bezafibrate

    CAS:
    <p>Bezafibrate (BM15075) is an antilipemic agent that lowers CHOLESTEROL and TRIGLYCERIDES.</p>
    Formula:C19H20ClNO4
    Purezza:99.56% - 99.82%
    Colore e forma:Solid
    Peso molecolare:361.82
  • Muraglitazar

    CAS:
    <p>Muraglitazar (BMS-298585) is a PPAR α/γ dual agonist for the treatment of type 2 diabetes and associated dyslipidemia.</p>
    Formula:C29H28N2O7
    Purezza:99.17%
    Colore e forma:Solid
    Peso molecolare:516.54
  • LY518674

    CAS:
    <p>LY518674 (LY-674) decreases triglycerides and increases HDL-C and is used for the treatment of atherosclerosis.</p>
    Formula:C23H27N3O4
    Purezza:98.87%
    Colore e forma:Solid
    Peso molecolare:409.48
  • EHP-101

    CAS:
    <p>EHP-101 is a PPARγ/CB2 dual agonist with anti-inflammatory properties, inhibits fat formation, and combats diet-related obesity.</p>
    Formula:C28H35NO3
    Purezza:98.36%
    Colore e forma:Solid
    Peso molecolare:433.58
  • NTP42

    CAS:
    <p>NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)</p>
    Formula:C25H23F2N3O5S
    Purezza:97.55%
    Colore e forma:Solid
    Peso molecolare:515.53
  • Gemfibrozil

    CAS:
    <p>Gemfibrozil, a fibric acid derivative, stimulates PPARalpha, boosts fatty acid oxidation, LPL, lowers VLDL-C, apoC-III, and raises HDL-C.</p>
    Formula:C15H22O3
    Purezza:99.53% - 99.88%
    Colore e forma:Crystals From Hexane Solid
    Peso molecolare:250.33
  • Rosiglitazone maleate

    CAS:
    <p>Rosiglitazone maleate (BRL 49653) is an oral antidiabetic and potential anticancer agent.</p>
    Formula:C22H23N3O7S
    Purezza:99.33% - 99.51%
    Colore e forma:Off-White Solid
    Peso molecolare:473.50
  • Anandamide

    CAS:
    <p>Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but also</p>
    Formula:C22H37NO2
    Purezza:95.037% - 99.22%
    Colore e forma:Light Yellow Oil
    Peso molecolare:347.53
  • Oleoylethanolamide

    CAS:
    <p>Oleoylethanolamide (N-Oleoylethanolamide) is a high affinity endogenous agonist of PPAR-α.</p>
    Formula:C20H39NO2
    Purezza:99.98%
    Colore e forma:Solid
    Peso molecolare:325.53
  • Daidzein

    CAS:
    <p>Daidzein (Isoflavone) is an isoflavone extract from soy, which is an inactive analog of the tyrosine kinase inhibitor genistein.</p>
    Formula:C15H10O4
    Purezza:98.08%
    Colore e forma:Solid
    Peso molecolare:254.24
  • Fenofibrate

    CAS:
    <p>Fenofibrate (Lipanthyl) is a PPARα agonist. Fenofibrate inhibits cytochrome P450 isoforms. Fenofibrate exhibits antihyperlipidemic activity. Cost-effective and quality-assured.</p>
    Formula:C20H21ClO4
    Purezza:99.13% - 99.95%
    Colore e forma:Crystals From Isopropanol Solid
    Peso molecolare:360.83
  • Mifobate

    CAS:
    Mifobate (SR-202) 是一种有效且特异性的 PPARγ拮抗剂,可选择性抑制噻唑烷二酮 (TZD) 诱导的 PPARγ 转录活性,IC50为140 μM,具有抗肥胖和抗糖尿病作用。
    Formula:C11H17ClO7P2
    Purezza:99.12%
    Colore e forma:Solid
    Peso molecolare:358.65
  • 5-Aminosalicylic Acid

    CAS:
    <p>5-Aminosalicylic Acid (5-ASA) is a specific PPARγ agonist and also inhibits P21-activated kinase 1 (PAK1) and NF-Κb. High-Quality, Low-Cost!</p>
    Formula:C7H7NO3
    Purezza:98.88% - 99.49%
    Colore e forma:Purplish-Tan Solid Powder
    Peso molecolare:153.14
  • Pioglitazone hydrochloride

    CAS:
    <p>Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic</p>
    Formula:C19H20N2O3S·HCl
    Purezza:99.64% - >99.99%
    Colore e forma:White Crystals Or Crystalline Powder
    Peso molecolare:392.90
  • MK-0533

    CAS:
    <p>MK-0533 is a novel PPARγ partial agonist for the prevention of vascular endothelial dysfunction (VED) and VED-related cardiovascular disease.</p>
    Formula:C28H24F3NO6
    Purezza:99.03%
    Colore e forma:Soild
    Peso molecolare:527.49
  • GW7647

    CAS:
    <p>GW 7647 is an effective and highly selective PPARα agonist. GW 7647 can reduce the production of nitric oxide in macrophages. Cost-effective and quality-assured.</p>
    Formula:C29H46N2O3S
    Purezza:99.3% - 99.34%
    Colore e forma:Solid
    Peso molecolare:502.75
  • Pioglitazone

    CAS:
    <p>Pioglitazone (U 72107) is a selective and oral PPARγ agonist with EC50 of 0.93 and 0.99 μM on human and mouse PPARγ, respectively . High-Quality, Low-Cost!</p>
    Formula:C19H20N2O3S
    Purezza:95% - 99.57%
    Colore e forma:White Powder
    Peso molecolare:356.44
  • Arhalofenate

    CAS:
    <p>Arhalofenate (JNJ 39659100) is a selective partial agonist of peroxisome proliferator-activated receptor PPARγ. It is used for the treatment of type 2 diabetes.</p>
    Formula:C19H17ClF3NO4
    Purezza:98.97%
    Colore e forma:Solid
    Peso molecolare:415.79
  • β-Amyrone

    CAS:
    <p>beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM.</p>
    Formula:C30H48O
    Purezza:99.55%
    Colore e forma:Solid
    Peso molecolare:424.7
  • Magnolol

    CAS:
    <p>Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.</p>
    Formula:C18H18O2
    Purezza:99.49%
    Colore e forma:A Bioactive Compound Found In The Bark Of The Houpu Magnolia
    Peso molecolare:266.33
  • WAY-620472

    CAS:
    <p>WAY-620472 is a PPAR regulator that can be used to alter the lifespan of eukaryotes.</p>
    Formula:C23H21N5OS
    Purezza:98.07%
    Colore e forma:Solid
    Peso molecolare:415.51
  • Nuclear Receptor Compound Library


    <p>A unique collection of 531 nuclear receptor signaling targeted compounds for high throughput and high content screening;</p>
    Colore e forma:Odour Solid
  • Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)-

    CAS:
    <p>Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM.</p>
    Formula:C24H23NO5S
    Purezza:99.59%
    Colore e forma:Soild
    Peso molecolare:437.51
  • PPAR agonist 6


    <p>PPAR agonist6 (compound 5a) acts as an agonist for PPAR, exhibiting EC50 values of 3.6 μM and 2.6 μM for PPARα and PPARβ/δ respectively. Additionally, PPAR agonist6 inhibits the transactivation of a TNFα-dependent NF-κB-driven reporter gene in L929 cells [1].</p>
    Colore e forma:Odour Solid
  • SP4f


    <p>SP4f, an activator of PPAR-γ, exhibits an EC50 value of 826 nM in HK-2 cells.</p>
    Purezza:98%
    Colore e forma:Odour Solid
  • Sulotroban potassium


    <p>Sulotroban potassium is a small molecule thromboxane A2 receptor (TXA2R) antagonist that can be used to study myocardial infarction and thrombosis.</p>
    Formula:C16H16KNO5S
    Purezza:98.02%
    Colore e forma:Soild
    Peso molecolare:373.46
  • Lipid Metabolism Compound Library


    <p>A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).</p>
    Colore e forma:Odour Solid
  • 8-iso Prostaglandin F1β

    CAS:
    <p>8-iso Prostaglandin F1β,inducet vasoconstrictor effects in (PA), (PV) and (MA) through the activation of TXA2R, tyrosine kinase and Rho kinase.</p>
    Formula:C20H36O5
    Colore e forma:Solid
    Peso molecolare:356.5
  • 8-iso Prostaglandin F1α

    CAS:
    <p>8-iso Prostaglandin F1α induces vasoconstrictor effects in (PA),(PV) and (MA) through activation of TXA2R, tyrosine kinases and Rho kinases.</p>
    Formula:C20H36O5
    Colore e forma:Solid
    Peso molecolare:356.5
  • Anti-osteoporosis agent-10


    <p>Anti-osteoporosis agent-10 is an inhibitor of osteoporosis that suppresses the formation of osteoclasts with an IC50 of 0.042 μM. It also exhibits antagonistic activity towards PPARγ, with an EC50 value of 0.75 μM.</p>
    Colore e forma:Odour Solid
  • SP4e


    <p>SP4e is a PPAR-γ activator.SP4e was effective in decreasing blood glucose, total cholesterol, triglycerides and LDL levels and increasing HDL levels.</p>
    Formula:C22H17ClN2O2S2
    Purezza:99.79%
    Colore e forma:Soild
    Peso molecolare:440.97
  • (±)-CBCQ

    CAS:
    <p>(±)-CBCQ, an oxidation product of cannabidiol, exhibits an EC50 value of 14.7 μM for the activation of peroxisome proliferator-activated receptor γ (PPAR-γ).</p>
    Formula:C21H28O3
    Colore e forma:Solid
    Peso molecolare:328.45
  • CC618

    CAS:
    <p>CC618 is a selective PPARβ/δ antagonist with an IC50 of 10.0 μM.</p>
    Formula:C20H15F6N3O3S2
    Purezza:99.94%
    Colore e forma:Solid
    Peso molecolare:523.47
  • MCC-555

    CAS:
    <p>MCC-555 (Isaglitazone) is a PPARα and PPARγ agonist exerting antihyperglycemic effects.</p>
    Formula:C21H16FNO3S
    Purezza:99.07% - 99.82%
    Colore e forma:Solid
    Peso molecolare:381.42
  • Sulotroban

    CAS:
    <p>sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.</p>
    Formula:C16H17NO5S
    Purezza:98.86% - 99.88%
    Colore e forma:Solid
    Peso molecolare:335.37
  • AZD-9574

    CAS:
    <p>AZD-9574 is a selective inhibitor of PARP1 at the sites of SSBs.</p>
    Formula:C21H22F2N6O2
    Purezza:98.46% - 99.39%
    Colore e forma:Solid
    Peso molecolare:428.44
  • E0924G

    CAS:
    <p>E0924G is an orally active PPARδ agonist with an EC50 of 2.82 μM. It enhances the upregulation of osteoprotegerin (OPG) expression, with an EC50 of 0.29 μM. E0924G reduces RANKL-induced osteoclast differentiation and inhibits F-actin ring formation in RAW264.7 macrophages. Additionally, E0924G modulates bone density and bone loss in models of ovariectomy (OVX) and age-related osteoporosis.</p>
    Formula:C12H12N2O3
    Colore e forma:Solid
    Peso molecolare:232.24
  • Anti-obesity agent 1


    <p>Compound 4 (Anti-obesity agent 1) demonstrates potential for enhanced lipolysis, highlighting its anti-obesity characteristics.</p>
    Formula:C21H22N2O6
    Colore e forma:Solid
    Peso molecolare:398.409
  • PPARγ agonist 15


    <p>PPARγ agonist15 (Compound 7c) functions as an agonist of PPARγ, inhibiting the expression of α-amylase (HPA) and α-glucosidase (HLAG) with IC50 values of 28.35 µM and 26.21 µM, respectively. It enhances glucose uptake in L6 myotubes and improves glucose homeostasis, insulin sensitivity, and lipid metabolism in a rat model of Streptozotocin-induced diabetes.</p>
    Formula:C21H16N4O3S2
    Colore e forma:Solid
    Peso molecolare:436.51
  • PPARγ agonist 16

    CAS:
    <p>PPARγ agonist16 (Compound 4G) is a PPARγ agonist that competitively binds to the ligand-binding domain (LBD) of PPARγ with an IC50 of 1790 nM. It reduces ear swelling in mouse models and exhibits antihyperglycemic activity in mice with Streptozotocin-induced diabetes.</p>
    Formula:C19H14BrNO4S
    Colore e forma:Solid
    Peso molecolare:432.29
  • Mavodelpar free acid hydrochloride


    <p>Mavodelpar free acid hydrochloride (Pparδ agonist HCl) is a potent PPARδ agonist.</p>
    Formula:C31H31ClFNO5
    Purezza:98.13%
    Colore e forma:Soild
    Peso molecolare:552.03
  • CUDA

    CAS:
    <p>CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively.</p>
    Formula:C19H36N2O3
    Purezza:97.585%
    Colore e forma:Solid
    Peso molecolare:340.5
  • GW590735

    CAS:
    <p>GW590735: PPARα agonist, EC50=4 nM, &gt;500x selective over PPARδ/γ, for dyslipidemia research.</p>
    Formula:C23H21F3N2O4S
    Purezza:99.53%
    Colore e forma:Solid
    Peso molecolare:478.48
  • PPARγ-IN-3


    <p>PPARγ-IN-3 (compound 9ga), a potent and orally active PPARγ inhibitor, effectively reduces triglyceride (TG) accumulation and exhibits low cytotoxicity. Additionally, it prevents excessive body weight gain, lessens fat and liver mass, and decreases lipid accumulation in both the liver and blood. PPARγ-IN-3 holds promise for research into diet-induced obesity.</p>
    Formula:C23H28FN7O3
    Colore e forma:Solid
    Peso molecolare:469.51
  • GQ-16

    CAS:
    <p>GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain.</p>
    Formula:C19H16BrNO3S
    Purezza:99.84%
    Colore e forma:Solid
    Peso molecolare:418.3
  • CP-868388 free base

    CAS:
    <p>CP-868388 free base (CP-868388) is a PPARα agonist with hypolipidemic and anti-inflammatory activity and is used in the study of dyslipidemia.</p>
    Formula:C26H33NO5
    Purezza:99.84%
    Colore e forma:Solid
    Peso molecolare:439.54
  • PPAR α/PPARA Protein, Human, Recombinant (His)


    <p>PPAR alpha/PPARA Protein, Human, Recombinant (His) is expressed in E.</p>
    Colore e forma:Lyophilized Powder
    Peso molecolare:31.36 kDa (predicted)
  • PPAR α/PPARA Protein, Mouse, Recombinant (His)


    <p>PPAR alpha/PPARA Protein, Mouse, Recombinant (His) is expressed in E.</p>
    Colore e forma:Lyophilized Powder
    Peso molecolare:31.49 kDa (predicted)
  • Balaglitazone

    CAS:
    <p>Balaglitazone is a PPARγ agonist that regulates blood glucose and is used in studies of heart failure and myocardial infarction.</p>
    Formula:C20H17N3O4S
    Purezza:99.74%
    Colore e forma:Solid
    Peso molecolare:395.43
  • Ciprofibrate

    CAS:
    <p>Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.</p>
    Formula:C13H14Cl2O3
    Purezza:99.63% - >99.99%
    Colore e forma:White Or Almost White Crystalline Powder
    Peso molecolare:289.15
  • Avicularin

    CAS:
    <p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>
    Formula:C20H18O11
    Purezza:97.02% - 99.94%
    Colore e forma:White Powder
    Peso molecolare:434.35
  • MK-886

    CAS:
    MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP).
    Formula:C27H34ClNO2S
    Purezza:99.23% - 99.84%
    Colore e forma:Solid
    Peso molecolare:472.08
  • LJ570

    CAS:
    <p>LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)</p>
    Formula:C27H22O3
    Purezza:99.64%
    Colore e forma:Solid
    Peso molecolare:394.46
  • Choline Fenofibrate

    CAS:
    <p>Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic</p>
    Formula:C22H28ClNO5
    Purezza:98.82%
    Colore e forma:Solid
    Peso molecolare:421.91
  • Rosiglitazone

    CAS:
    <p>Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.</p>
    Formula:C18H19N3O3S
    Purezza:98.61% - 99.87%
    Colore e forma:White To Off-White Crystalline Powder
    Peso molecolare:357.43
  • NPC 15199

    CAS:
    <p>NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.</p>
    Formula:C21H23NO4
    Purezza:99.93% - 99.94%
    Colore e forma:White Crystalline Powder
    Peso molecolare:353.41
  • Seladelpar

    CAS:
    <p>Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia.</p>
    Formula:C21H23F3O5S
    Purezza:99.18% - 99.41%
    Colore e forma:Solid
    Peso molecolare:444.46
  • Norathyriol

    CAS:
    <p>Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.</p>
    Formula:C13H8O6
    Purezza:99.35% - 99.55%
    Colore e forma:Solid
    Peso molecolare:260.2
  • Pirinixic Acid

    CAS:
    <p>Pirinixic Acid (NSC 310038) is a synthetic thiacetic acid derivative used in biomedical research, a peroxisome proliferator that activates specific PPAR.</p>
    Formula:C14H14ClN3O2S
    Purezza:98.27% - 99.92%
    Colore e forma:Solid
    Peso molecolare:323.8
  • Bilobetin

    CAS:
    <p>Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.</p>
    Formula:C31H20O10
    Purezza:97.74% - 99.69%
    Colore e forma:Solid
    Peso molecolare:552.48
  • GW 501516

    CAS:
    <p>GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.</p>
    Formula:C21H18F3NO3S2
    Purezza:98.91% - 99.64%
    Colore e forma:White Solid
    Peso molecolare:453.50
  • OPHIOPOGONIN D

    CAS:
    <p>Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.</p>
    Formula:C44H70O16
    Purezza:99.46% - ≥95%
    Colore e forma:Solid
    Peso molecolare:855.02
  • BMS-687453

    CAS:
    <p>BMS-687453 is a potent and selective PPAR alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma</p>
    Formula:C22H21ClN2O6
    Purezza:99.4%
    Colore e forma:Solid
    Peso molecolare:444.86
  • Licarin B

    CAS:
    <p>1.(-)-Licarin B (Licarine B) has anti-mycobacterial activity.</p>
    Formula:C20H20O4
    Purezza:99.82% - ≥95%
    Colore e forma:Solid
    Peso molecolare:324.37
  • Eupatilin

    CAS:
    <p>Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.</p>
    Formula:C18H16O7
    Purezza:98.53% - 99%
    Colore e forma:Solid
    Peso molecolare:344.32
  • GW9662

    CAS:
    <p>GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!</p>
    Formula:C13H9ClN2O3
    Purezza:98% - 99.95%
    Colore e forma:Off-White Solid
    Peso molecolare:276.68
  • SR1664

    CAS:
    <p>SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity.</p>
    Formula:C33H29N3O5
    Purezza:98.02%
    Colore e forma:Solid
    Peso molecolare:547.6
  • FH535

    CAS:
    <p>FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.</p>
    Formula:C13H10Cl2N2O4S
    Purezza:98.25% - 99.5%
    Colore e forma:Solid
    Peso molecolare:361.2
  • Icariin

    CAS:
    <p>Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.</p>
    Formula:C33H40O15
    Purezza:97.82% - 98.3%
    Colore e forma:Solid
    Peso molecolare:676.66
  • Glabrone

    CAS:
    <p>Glabrone shows antiviral activity against influenza virus.</p>
    Formula:C20H16O5
    Purezza:99.08% - 99.55%
    Colore e forma:Solid
    Peso molecolare:336.34
  • GW6471

    CAS:
    <p>GW6471 is an antagonist of PPARα. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.</p>
    Formula:C35H36F3N3O4
    Purezza:98.23% - 99.55%
    Colore e forma:Solid
    Peso molecolare:619.67
  • Palmitelaidic Acid

    CAS:
    <p>Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.</p>
    Formula:C16H30O2
    Purezza:99.76%
    Colore e forma:Solid
    Peso molecolare:254.41
  • NSC-87877 disodium

    CAS:
    <p>NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.</p>
    Formula:C19H13N3O7S2·2Na
    Purezza:97.89%
    Colore e forma:Solid
    Peso molecolare:503.42
  • SR 16832

    CAS:
    <p>SR 16832: Dual-site PPARγ inhibitor; outperforms GW 9662, T 0070907 in ligand binding, transcription inhibition.</p>
    Formula:C17H12ClN3O4
    Purezza:99.6%
    Colore e forma:Solid
    Peso molecolare:357.75
  • GW0742

    CAS:
    <p>GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for human PPARδ/α/γ).</p>
    Formula:C21H17F4NO3S2
    Purezza:99.75% - 99.85%
    Colore e forma:Solid
    Peso molecolare:471.49
  • CDDO-Im

    CAS:
    <p>CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).</p>
    Formula:C34H43N3O3
    Purezza:98.3% - 99.61%
    Colore e forma:Solid
    Peso molecolare:541.72
  • SC-236

    CAS:
    <p>SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).</p>
    Formula:C16H11ClF3N3O2S
    Purezza:99.74%
    Colore e forma:Solid
    Peso molecolare:401.79
  • Raspberry ketone

    CAS:
    <p>1.</p>
    Formula:C10H12O2
    Purezza:99.84% - 99.89%
    Colore e forma:White Solid Crystalline
    Peso molecolare:164.2
  • Fisetin

    CAS:
    <p>Fisetin belongs to a group of natural flavonols with anti-inflammatory, antioxidant, anti-tumor, anti-aging and neuroprotective effects. Cost effective and quality assured.</p>
    Formula:C15H10O6
    Purezza:94.14% - 99.05%
    Colore e forma:Yellow To Brown Crystalline Powder
    Peso molecolare:286.24
  • Ginsenoside Rh1

    CAS:
    <p>Ginsenoside Rh1 (Sanchinoside B2) , one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.</p>
    Formula:C36H62O9
    Purezza:99% - 99.77%
    Colore e forma:Solid
    Peso molecolare:638.87
  • Alpinetin

    CAS:
    <p>Alpinetin: antibacterial, anti-inflammatory, boosts HepG2 sensitivity to CDDP, fights hepatoma/pancreatic cancer, inhibits cell growth &amp; activates caspases.</p>
    Formula:C16H14O4
    Purezza:98.39%
    Colore e forma:Solid
    Peso molecolare:270.28
  • Glabridin

    CAS:
    <p>Glabridin aids in diabetes by reducing inflammation and glucose levels and may prevent liver cancer spread.</p>
    Formula:C20H20O4
    Purezza:99.78% - 99.99%
    Colore e forma:Light Yellow Powder Insoluble In Water
    Peso molecolare:324.37
  • Convallatoxin

    CAS:
    <p>Convallatoxin is a natural product.</p>
    Formula:C29H42O10
    Purezza:99.27% - 99.53%
    Colore e forma:Prisms From Methanol + Ether Solid
    Peso molecolare:550.64
  • Methyl oleanonate

    CAS:
    <p>3-Oxoolean-12-en-28-oic acid methyl ester is a triterpenoid PPARγ agonist isolated from Pistacia with anticancer properties.</p>
    Formula:C31H48O3
    Purezza:98.99%
    Colore e forma:Solid
    Peso molecolare:468.71
  • Astaxanthin

    CAS:
    <p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>
    Formula:C40H52O4
    Purezza:95.1% - 99.79%
    Colore e forma:Needles From Acetone/Light Petroleum Solid
    Peso molecolare:596.84
  • Agrimol B

    CAS:
    <p>1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.</p>
    Formula:C37H46O12
    Purezza:99.06% - ≥95%
    Colore e forma:Solid
    Peso molecolare:682.75
  • (E/Z)-Elafibranor

    CAS:
    <p>GFT505 (Elafibranor) (Elafibranor) is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively.</p>
    Formula:C22H24O4S
    Purezza:98.36%
    Colore e forma:Solid
    Peso molecolare:384.49
  • Adelmidrol

    CAS:
    <p>Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.</p>
    Formula:C13H26N2O4
    Purezza:99.35% - 99.73%
    Colore e forma:Solid
    Peso molecolare:274.36
  • GW1929

    CAS:
    <p>GW1929 is a potent PPAR-γ agonist (pKi: 8.84 for human PPAR-γ; pEC50s of 8.56 and 8.27 for human and murine PPAR-γ).</p>
    Formula:C30H29N3O4
    Purezza:98.1% - 98.21%
    Colore e forma:Solid
    Peso molecolare:495.57
  • Bocidelpar

    CAS:
    <p>Bocidelpar is a modulator of PPARδ with an EC50 of 7.80 nM and improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy muscle cells.</p>
    Formula:C25H27F3N2O3
    Purezza:97.77%
    Colore e forma:Solid
    Peso molecolare:460.49
  • Troglitazone

    CAS:
    <p>Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.</p>
    Formula:C24H27NO5S
    Purezza:98% - 99.8%
    Colore e forma:Yellow Solid
    Peso molecolare:441.54
  • Tetradecylthioacetic acid

    CAS:
    <p>Synthetic fatty acid TTA has β-sulfur, resists β-oxidation, and activates PPARs, especially PPARα.</p>
    Formula:C16H32O2S
    Purezza:99.93%
    Colore e forma:Solid
    Peso molecolare:288.49
  • T0070907

    CAS:
    <p>T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the &gt;800-fold selectivity over PPARα and PPARδ.</p>
    Formula:C12H8ClN3O3
    Purezza:98.25% - 99.98%
    Colore e forma:Solid
    Peso molecolare:277.66
  • Angeloylgomisin H

    CAS:
    <p>Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines.</p>
    Formula:C28H36O8
    Purezza:99.84% - 99.95%
    Colore e forma:Solid
    Peso molecolare:500.58
  • Oleuropein

    CAS:
    <p>Oleuropein is an antioxidant polyphenol isolated from olive leaf.</p>
    Formula:C25H32O13
    Purezza:98% - 99.95%
    Colore e forma:Brown Powder
    Peso molecolare:540.51
  • GSK0660

    CAS:
    <p>GSK0660 is an antagonist and inverse agonist of PPARβ/δ.</p>
    Formula:C19H18N2O5S2
    Purezza:99.26% - ≥95%
    Colore e forma:Solid
    Peso molecolare:418.49
  • Rosiglitazone hydrochloride

    CAS:
    <p>Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.</p>
    Formula:C18H19N3O3S·HCl
    Purezza:99.63% - 99.79%
    Colore e forma:Solid
    Peso molecolare:393.89
  • EPI-001

    CAS:
    <p>EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ~6 μM and a selective PPAR-gamma modulator.</p>
    Formula:C21H27ClO5
    Purezza:99% - 99.67%
    Colore e forma:Solid
    Peso molecolare:394.89
  • Clofibrate

    CAS:
    <p>Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity.</p>
    Formula:C12H15ClO3
    Purezza:98.77%
    Colore e forma:Oil Liquid
    Peso molecolare:242.70
  • DG172 dihydrochloride

    CAS:
    <p>DG172 dihydrochloride (DG-172 dihydrochloride) is an antagonist of PPARβ/δ(IC50 : 27 nM).</p>
    Formula:C20H22BrCl2N3
    Purezza:99.87%
    Colore e forma:Solid
    Peso molecolare:455.2
  • L-165041

    CAS:
    <p>L-165041 is a potent and selective agonist of the nuclear receptor PPARβ and PPARδ(Ki = 9 nM, EC50 = ~500 nM ,respectively)</p>
    Formula:C22H26O7
    Purezza:97.97%
    Colore e forma:Solid
    Peso molecolare:402.44
  • GSK3787

    CAS:
    <p>GSK3787 is a specific and irreversible PPARδ inhibitor(pIC50= 6.6).</p>
    Formula:C15H12ClF3N2O3S
    Purezza:98% - 99.56%
    Colore e forma:Solid
    Peso molecolare:392.78
  • Oroxin A

    CAS:
    <p>Oroxin A (Baicalein 7-O-glucoside) has antitussive and expectorant effects.</p>
    Formula:C21H20O10
    Purezza:98.05% - 99.74%
    Colore e forma:Solid
    Peso molecolare:432.38
  • AMG131

    CAS:
    <p>AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used for</p>
    Formula:C21H12Cl4N2O3S
    Purezza:99.37%
    Colore e forma:Solid
    Peso molecolare:514.21
  • Gypenoside XLIX

    CAS:
    <p>Extracted from whole herb of Gynostemsma pentaphyllum(Thunb.)Mak.;Store the product in sealed, cool and dry condition</p>
    Formula:C52H86O21
    Purezza:97.05% - 99.78%
    Colore e forma:Solid
    Peso molecolare:1047.23
  • Elafibranor

    CAS:
    <p>Elafibranor (GFT505) is an agonist of the peroxisome proliferator-activated receptor-α (PPAR-α) and peroxisome proliferator-activated receptor-δ (PPAR-δ) with</p>
    Formula:C22H24O4S
    Purezza:98.42% - 98.78%
    Colore e forma:Solid
    Peso molecolare:384.49
  • Cinnamyl alcohol

    CAS:
    <p>Cinnamyl alcohol (Styryl Carbinol) readily autoxidizes upon air exposure, and forms strong sensitizers as determined by the local lymph node assay.</p>
    Formula:C9H10O
    Purezza:99.00%
    Colore e forma:Colourless Liquid
    Peso molecolare:134.18
  • Tesaglitazar

    CAS:
    <p>Tesaglitazar is a potent and selective peroxide PPARα / γ receptor dual agonist with a more potent affinity for PPARγ than PPARα, The EC50 values for rat PPARα</p>
    Formula:C20H24O7S
    Purezza:99.95%
    Colore e forma:Solid
    Peso molecolare:408.47
  • Pparδ agonist 2

    CAS:
    <p>Pparδ agonist 2 is an agonist of PPARδ.</p>
    Formula:C20H18F3N3O3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:437.44
  • FTX-6746

    CAS:
    <p>FTX-6746 is an orally active and selective PPARG reverse inhibitor with anticancer activity. It can be used in research on urothelial carcinoma.</p>
    Formula:C16H7ClF2N2O
    Purezza:98.68%
    Colore e forma:Solid
    Peso molecolare:316.69
  • 13-Oxo-9E,11E-octadecadienoic acid

    CAS:
    <p>13-Oxo-9E,11E-octadecadienoic acid from tomato juice, an isomer of 9-oxo-ODA, activates PPARα and lowers triglycerides in diabetic mice.</p>
    Formula:C18H30O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:294.43
  • Peliglitazar racemate

    CAS:
    <p>Peliglitazar racemate(BMS 426707-01 racemate) is the racemate of Peliglitazar.Peliglitazar racemate may be used as a potential antidiabetic and anti-obesity</p>
    Formula:C30H30N2O7
    Purezza:97.75%
    Colore e forma:Solid
    Peso molecolare:530.57
  • Daltroban

    CAS:
    <p>Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist.</p>
    Formula:C16H16ClNO4S
    Purezza:99.74%
    Colore e forma:Solid
    Peso molecolare:353.82
  • GW 9578

    CAS:
    <p>GW 9578 is a PPARα agonist with potent lipid-lowering activity for the study of psoriasis, arthritis, alopecia, asthma and type I diabetes.</p>
    Formula:C26H34F2N2O3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:492.62
  • ARH-049020

    CAS:
    <p>ARH-049020, a peroxisome proliferator-activated receptor (PPAR) agonist, is used potentially for the treatment of insulin resistance and type 2 diabetes.</p>
    Formula:C24H31NO6
    Purezza:97.19% - 99.82%
    Colore e forma:Solid
    Peso molecolare:429.51
  • Reglitazar

    CAS:
    <p>Reglitazar, a dual PPARα/γ agonist, enhances insulin signaling, reduces insulin resistance, and lowers hypertriglyceridemia in obese rats.</p>
    Formula:C22H20N2O5
    Purezza:97.07% - 98.72%
    Colore e forma:Solid
    Peso molecolare:392.4
  • THR-0921

    CAS:
    <p>THR-0921 (CLX-0921) is a peroxisome proliferator-activated receptor (PPAR) agonist that can be used to study cardiovascular and metabolic diseases.</p>
    Formula:C28H25NO7S
    Purezza:100% - 99.83%
    Colore e forma:Solid
    Peso molecolare:519.57
  • AVE-8134

    CAS:
    <p>AVE-8134 is an agonist of PPARα. For human and rodent PPARα receptor, the EC50 values are 100 and 3000 nM, respectively.</p>
    Formula:C22H23NO5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:381.42
  • PPARα-MO-1

    CAS:
    <p>PPARα-MO-1 is a potent modulator of PPARα.</p>
    Formula:C27H37NO5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:455.59
  • LG100754

    CAS:
    <p>LG100754 (UVI 2112) is an insulin sensitizer and RXR modulator, antagonizing RXR homodimers while agonizing RXR:PPARα/γ heterodimers.</p>
    Formula:C26H36O3
    Colore e forma:Solid
    Peso molecolare:396.56
  • Chiglitazar

    CAS:
    <p>Chiglitazar is a PPAR α/γ/δ agonist and insulin sensitizer used in the treatment of type 2 diabetes mellitus , anti-inflammatory and anti-fibrotic.</p>
    Formula:C36H29FN2O4
    Colore e forma:Solid
    Peso molecolare:572.63
  • Inolitazone dihydrochloride

    CAS:
    <p>Inolitazone dihydrochloride is an effective, high-affinity PPARγ agonist; its biological activity is dependent on PPARγ (IC50:0.8 nM) to inhibit cell growth.</p>
    Formula:C27H28Cl2N4O4S
    Colore e forma:Solid
    Peso molecolare:575.51
  • Saroglitazar

    CAS:
    <p>Saroglitazar (Lipaglyn) is an agonist of PPAR with EC50 values of 0.65 pM and 3 nM for PPARα and PPARγ.</p>
    Formula:C25H29NO4S
    Purezza:98.51%
    Colore e forma:Solid
    Peso molecolare:439.57
  • GSK376501A

    CAS:
    <p>GSK376501A is a selective and effective modulator of peroxisome proliferator-activated receptor γ (PPARγ) for the study of type 2 diabetes.</p>
    Formula:C32H37NO6
    Purezza:>99.99%
    Colore e forma:Solid
    Peso molecolare:531.64
  • Indeglitazar

    CAS:
    <p>Indeglitazar (PPM 204) is orally available pan-agonist of PPAR (PPAR subtypes alpha (α), delta (δ), and gamma (γ)).</p>
    Formula:C19H19NO6S
    Purezza:99.45%
    Colore e forma:Solid
    Peso molecolare:389.42
  • K-111

    CAS:
    <p>K-111 is a PPAR alpha agonist. K-111 improves insulin resistance, reducing bodyweight, and ameliorating atherogenic dyslipidemia.</p>
    Formula:C18H25Cl3O2
    Purezza:99.64% - 99.88%
    Colore e forma:Solid
    Peso molecolare:379.75
  • Farglitazar

    CAS:
    <p>Farglitazar (GI-262570) is a PPAR-γ agonist and insulin sensitizer used in the study of diabetes.</p>
    Formula:C34H30N2O5
    Purezza:99.4% - 99.52%
    Colore e forma:Solid
    Peso molecolare:546.61
  • Cevoglitazar

    CAS:
    <p>Cevoglitazar (LBM-642) is a PPARɑ agonist and PPARγ agonist. Cevoglitazar potently reduces food intake and body weight in obese mice and cynomolgus monkeys.</p>
    Formula:C27H21F3N2O6S
    Purezza:98.75%
    Colore e forma:Solid
    Peso molecolare:558.53
  • Dazmegrel

    CAS:
    <p>Dazmegrel (UK 38,485) is a thromboxane A2 (TXA2) synthase inhibitor for the prevention of increased whole platelet aggregation in normal pregnancy.</p>
    Formula:C16H17N3O2
    Purezza:98.81%
    Colore e forma:Solid
    Peso molecolare:283.33
  • BAY-0069

    CAS:
    <p>BAY-0069 is a potent and selective PPARγ transactivator that inhibits human PPARγ and murine PPARγ with IC50s of 6.3 nM and 24 nM, respectively.BAY-0069 can be</p>
    Formula:C22H16BrN3O4
    Purezza:99.41%
    Colore e forma:Soild
    Peso molecolare:466.28
  • Linotroban

    CAS:
    <p>Linotroban(CL-871502) is a potent selective thromboxane (TXA2) receptor antagonist with antithrombotic activity.</p>
    Formula:C14H15NO5S2
    Purezza:97.95% - >99.99%
    Colore e forma:Solid
    Peso molecolare:341.4
  • BAY-4931

    CAS:
    <p>BAY-4931 is a powerful, covalent, and selective inverse-agonist of PPARγ, exhibiting an IC50 value of 0.17 nM.</p>
    Formula:C22H16ClN3O4
    Purezza:99.47%
    Colore e forma:Soild
    Peso molecolare:421.83
  • Edaglitazone

    CAS:
    <p>Edaglitazone (R-483) is a PPARγ agonist with antiplatelet activity that can be used in studies of diabetes and obesity.</p>
    Formula:C24H20N2O4S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:464.56
  • LCB-2853

    CAS:
    <p>LCB-2853 is a potent thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist with antiplatelet aggregation, antivasospasm, and antithrombotic effects.</p>
    Formula:C21H24ClNO4S
    Purezza:97.15%
    Colore e forma:Solid
    Peso molecolare:421.94
  • Imiglitazar

    CAS:
    <p>Imiglitazar (TAK559) is a potent PPAR-β/δ receptor agonist with hypoglycemic effects.</p>
    Formula:C28H26N2O5
    Purezza:97.33%
    Colore e forma:Solid
    Peso molecolare:470.52
  • PPAR agonist 1

    CAS:
    <p>PPAR agonist 1 is an agonist of PPAR α/γ, used for reducing blood glucose, lipid levels, reducing body weight, and lowering cholesterol.</p>
    Formula:C20H25NO6S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:407.48
  • U-46619

    CAS:
    <p>U-46619 is an effective thromboxane A2 (TXA2) agonist and a thromboxane A2 analog (endoperoxide), capable of inducing contraction in the aortic smooth muscle (</p>
    Formula:C21H34O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:350.49
  • KD-3010

    CAS:
    <p>KD-3010 (Kalypsys) is an orally active potent and selective PPARδ agonist for the study of liver injury.</p>
    Formula:C30H33F3N2O8S2
    Purezza:99.61%
    Colore e forma:Solid
    Peso molecolare:670.72
  • CRX000227

    CAS:
    <p>CRX000227 is a PPAR modulator suitable for researching metabolic and cell proliferative disorders [1].</p>
    Formula:C25H24N4O2S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:444.55
  • PPARγ agonist 8

    CAS:
    <p>PPARγ agonist 8, a compound that acts on the peroxisome proliferator-activated receptor gamma (PPARγ), has been shown to stimulate peroxisome proliferator</p>
    Formula:C19H12F4O2S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:380.36
  • Darglitazone

    CAS:
    <p>Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions.</p>
    Formula:C23H20N2O4S
    Purezza:99.76%
    Colore e forma:Solid
    Peso molecolare:420.48
  • PPARδ agonist 9

    CAS:
    <p>PPARδ agonist 9 (compound 21), with an EC50 of 3.6 nM, is effective in vivo, decreasing serum MCP-1 concentrations in mice and markedly reducing atherosclerotic</p>
    Formula:C26H28ClF3N4O3S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:569.04
  • Ragaglitazar

    CAS:
    <p>Ragaglitazar(NNC-61-0029) is a potent dual activator of PPARγ and PPARα.Cost-effective and quality-assured.</p>
    Formula:C25H25NO5
    Purezza:97.46% - 98.56%
    Colore e forma:Solid
    Peso molecolare:419.47
  • Inolitazone

    CAS:
    <p>Inolitazone (RS5444) a high-affinity PPARγ agonist. Inolitazone exhibits IC50 for growth inhibition is ~0.8 nM in vitro.</p>
    Formula:C27H26N4O4S
    Purezza:99.41% - 99.53%
    Colore e forma:Solid
    Peso molecolare:502.58
  • Fonadelpar

    CAS:
    <p>Fonadelpar is an agonist of PPARδ. It also is used in the research of neuroparalytic keratopathy.</p>
    Formula:C25H23F3N2O4S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:504.52
  • Anti-NASH agent 2

    CAS:
    <p>Anti-NASH agent 2 (compound 21) is an inhibitor of neolipogenesis activity and α-SMA gene expression. It improves hepatic steatosis, edema, inflammatory infiltration, and liver fibrosis in NASH mouse models.</p>
    Formula:C32H51N3O2
    Colore e forma:Solid
    Peso molecolare:509.766
  • PPARγ agonist 17

    CAS:
    <p>PPARγ agonist17 (Compound C1) is an orally active PPARγ agonist. It enhances PPARγ activity, arrests the cell cycle of HT-29 cells at the G2/M phase, inhibits cell migration, and induces apoptosis. PPARγ agonist17 exhibits broad-spectrum antiproliferative activity against cancer cells with relatively low toxicity to normal cells and does not cross the blood-brain barrier.</p>
    Formula:C48H63NO7
    Colore e forma:Solid
    Peso molecolare:766.016
  • PPARγ modulator-2

    CAS:
    <p>PPARγmodulator-2 (Compound (R)-2n) is a reversible modulator of PPARγ, inhibiting the PPARγ ligand-binding domain (LBD) with an IC50 of 41 nM. It helps lower blood glucose levels, improves glucose tolerance and insulin sensitivity, and demonstrates antidiabetic activity in db/db mouse models.</p>
    Formula:C26H21NO7S3Se
    Colore e forma:Solid
    Peso molecolare:634.6
  • Amezalpat

    CAS:
    <p>Amezalpat is a PPARα antagonist with an IC50 of 58 nM [nanomolar]. Amezalpat also exhibits antitumor activity.</p>
    Formula:C34H41N3O4
    Colore e forma:Solid
    Peso molecolare:555.707
  • PPARγ-IN-5

    CAS:
    <p>PPARγ-IN-5 (Compound A3) is an inhibitor of PPARγ. In liver cells, it reduces lipid accumulation and shows no significant cytotoxicity in HepG2 cells at a concentration of 400 µM. PPARγ-IN-5 is applicable for research on non-alcoholic fatty liver disease.</p>
    Formula:C22H23ClO7
    Colore e forma:Solid
    Peso molecolare:434.867
  • PPARα/δ agonist 3

    CAS:
    <p>PPARα/δ agonist 3 (Compound 8) is an orally active PPAR agonist capable of activating PPARα, PPARδ, and PPARγ, with EC50 values of 5.6 nM, 3.4 nM, and 1278 nM, respectively. It exhibits anti-cholestatic activity in mouse models of cholestatic liver disease induced by ANIT or CDCA.</p>
    Formula:C23H25F3N2O4
    Colore e forma:Solid
    Peso molecolare:450.451
  • PPARδ agonist 11

    CAS:
    <p>Compound 11, a selective PPARδ agonist, demonstrates an EC50 of 20 nM, indicating its high affinity for PPARδ receptors. This compound efficiently reduces levels of nitric oxide (NO), as well as the pro-inflammatory cytokines TNFα and IL-6 in LPS-stimulated RAW264.7 cells via the NF-κB pathway, showcasing its anti-inflammatory properties. Additionally, Compound 11 exhibits remarkable stability in human liver microsomes and plasma. It significantly ameliorates foot edema induced by Carrageenan, displaying favorable pharmacokinetic properties with a bioavailability of approximately 100%.</p>
    Formula:C19H15F3N2O3S2
    Colore e forma:Solid
    Peso molecolare:440.46
  • Aleglitazar

    CAS:
    <p>Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively.</p>
    Formula:C24H23NO5S
    Purezza:99.03%
    Colore e forma:Solid
    Peso molecolare:437.51
  • Anti-NASH agent 1

    CAS:
    <p>Anti-NASH Agent 1 (Compound 3d), derived from Elafibranor, serves as a strong PPAR-α/δ agonist aimed at treating nonalcoholic steatohepatitis (NASH).</p>
    Formula:C26H33NO4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:423.54

    Ref: TM-T79454

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  • PPARγ-IN-2

    CAS:
    <p>"PPARγ-IN-2 (Compound 5a), a PPARγ inhibitor, exhibits an EC50 of 0.106 μM in inhibiting TG accumulation in 3T3-L1 preadipocytes.</p>
    Formula:C19H21N5O
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:335.4

    Ref: TM-T79678

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  • Mavodelpar free base

    CAS:
    <p>Mavodelpar free acid (REN001 free acid) is an selective agonist of PPARδ.</p>
    Formula:C31H30FNO5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:515.57

    Ref: TM-T12527

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