Proteasi/Proteasoma
Gli inibitori delle proteasi e del proteasoma sono composti che bloccano l'attività delle proteasi e del proteasoma, che sono coinvolti nella degradazione e nel turnover delle proteine. Questi inibitori sono fondamentali per studiare la regolazione dell'omeostasi proteica, il controllo del ciclo cellulare e l'apoptosi. Gli inibitori delle proteasi e del proteasoma vengono anche utilizzati nel trattamento di malattie come il cancro, dove la degradazione anomala delle proteine svolge un ruolo nella progressione della malattia. Inibendo le proteasi o il proteasoma, questi composti possono indurre la morte cellulare nelle cellule tumorali e sono strumenti critici sia per la ricerca di base che per lo sviluppo terapeutico. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle proteasi e del proteasoma di alta qualità per supportare la tua ricerca in biochimica, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Proteasi/Proteasoma"
- Acetil-CoA carbossilasi(36 prodotti)
- Cisteina proteasi(110 prodotti)
- DPP-4(20 prodotti)
- Glutaminasi(44 prodotti)
- Proteasi HIV(506 prodotti)
- PAI-1(26 prodotti)
- Inibitori della proteasi(50 prodotti)
- Ricettore attivato dalla proteasi(54 prodotti)
- Proteasoma(95 prodotti)
- Proteasi serina(55 prodotti)
- p97(15 prodotti)
Mostrare 3 più sottocategorie
Trovati 1093 prodotti di "Proteasi/Proteasoma"
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HIV-1 TAT (48-60) Acetate
Lilotomab (HH1) is a murine anti-CD37 antibody that can be used to synthesize anti-CD37 antibody-radionuclide couplings.Formula:C72H135N35O18Purezza:99.93%Colore e forma:SoildPeso molecolare:1779.07L-Methionine-DL-sulfoximine
CAS:MSO blocks glutamine synthetase, impacts astroglia, and is used in convulsant research.Formula:C5H12N2O3SPurezza:99.56% - ≥98%Colore e forma:White Crystalline PowderPeso molecolare:180.23Cathepsin Inhibitor 4
<p>Cathepsin Inhibitor 4 (Compound 45) is a selective inhibitor of Cathepsin S, with a Ki value of 0.04 nM.</p>Formula:C24H35N3O5Peso molecolare:445.25767Proteasome-IN-7
Proteasome-IN-7 (Compound 6f) is a macrolactam-based epoxyketone proteasome inhibitor with an IC50 value of 37.92 nM against the 20S proteasome ChT-L subunit. It exhibits potent antiproliferative effects on multiple myeloma, acute lymphoblastic leukemia, and non-small cell lung cancer.Formula:C48H56N6O10SColore e forma:SolidPeso molecolare:909.06Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2
CAS:Dnp-P-Cha-G-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic probe for MMP-1 and MMP-9 detection, releasing fluorescent Nma upon cleavage (Ex/Em: 340/440 nm).Formula:C49H68N14O12SColore e forma:SolidPeso molecolare:1077.22Leptosphaerodione
CAS:Leptosphaerodione from Remotididymella sp.: a potent UPS inhibitor with 3.2 μM IC50 in HeLa cells; anti-tumor.Formula:C21H22O5Colore e forma:SolidPeso molecolare:354.4Cys-TAT(47-57) acetate(583836-55-9 Free base)
Cys-TAT(47-57) acetate is derived from the HIV-1 transactivating protein. Cys-TAT(47-57) acetate is an arginine rich peptide that can penetrate cells.Formula:C69H128N34O16SPurezza:95.1100%Colore e forma:SolidPeso molecolare:1722.04ZG36
ZG36, a human Caseinolytic protease P (ClpP) agonist, non-selectively degrades respiratory chain complexes and reduces mitochondrial DNA, causing mitochondrialColore e forma:Odour SolidDazcapistat
CAS:Dazcapistat is a potent calpain inhibitor, with IC50s of <3 μM for calpain 1, calpain 2 and calpain 9, respectively.Formula:C21H18FN3O4Purezza:99.11%Colore e forma:SolidPeso molecolare:395.38Ref: TM-T9710
1mg96,00€5mg202,00€10mg305,00€25mg550,00€50mg772,00€100mg1.074,00€1mL*10mM (DMSO)224,00€MMP-12 Inhibitor
CAS:<p>MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.</p>Formula:C19H20N2O7SPurezza:97.51% - 99.96%Colore e forma:SoildPeso molecolare:420.44CTTHWGFTLC, CYCLIC
CAS:CTT Gelatinase Inhibitor peptide blocks MMP-2/9, hindering cancer by stopping tumor growth.Formula:C52H71N13O14S2Purezza:98%Colore e forma:SolidPeso molecolare:1166.33Sofosbuvir impurity I
Sofosbuvir impurity I is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.Formula:C21H27FN3O9PPurezza:98%Colore e forma:SolidPeso molecolare:515.43Cathepsin C-IN-6
Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastaseFormula:C24H35N5O4·xC2HF3O2Colore e forma:SolidSofosbuvir impurity J
CAS:Sofosbuvir impurity J is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.Formula:C22H30FN4O8PPurezza:98%Colore e forma:SolidPeso molecolare:528.47Nitidanin
Nitidanin is a useful organic compound for research related to life sciences and the catalog number is T125599.Formula:C21H24O8Colore e forma:SolidPeso molecolare:404.415Sofosbuvir impurity H
Sofosbuvir impurity H, an diastereoisomer of Sofosbuvir, is the impurity of Sofosbuvir.Formula:C29H33FN3O10PPurezza:98%Colore e forma:SolidPeso molecolare:633.56SL44
SL44 is an agonist of human caseinolytic protease P (HsClpP) with an EC50 of 1.30 μM. It inhibits LM3 proliferation with an IC50 of 3.1 μM and induces apoptosis in liver cancer cells by degrading respiratory chain complex subunits. In mouse models, SL44 demonstrates antitumor activity without significant toxicity (LD50=400 mg/kg) and exhibits favorable pharmacokinetic properties in rat models.Formula:C22H20ClFN4OPeso molecolare:410.13097Hepcidin-1 (mouse)
CAS:Hepcidin-1 (mouse) is a peptide hormone that regulates iron balance, elevates mRNA for TRAP, cathepsin K, and MMP-9, and promotes TRAP-5b protein secretion.Formula:C111H169N31O35S8Colore e forma:SolidPeso molecolare:2754.24PF 00356231
CAS:<p>PF 00356231 is a selectivity inhibitor MMP-12 and can be used in studies about the treatment of emphysema and chronic obstructive pulmonary disease (COPD).</p>Formula:C25H20N2O3SPurezza:99.35%Colore e forma:SolidPeso molecolare:428.5MMP Inhibitor 4
MMP Inhibitor4 (compound 4 B) is an effective MMP inhibitor with anti-proliferative properties. It induces cell cycle arrest at the subG1 phase and reduces the mRNA expression of MMP2, MMP9, and VEGFA.Formula:C16H18BrClN2O5Colore e forma:SolidPeso molecolare:433.68Ac-DNLD-CHO
CAS:Ac-DNLD-CHO (Ac-Asp-Asn-Leu-Asp-CHO) is an inhibitor of Caspase-3/7, exhibiting IC50 values of 9.89 nM and 245 nM, and approximate Ki values of 0.68 nM and 55.7Formula:C20H31N5O10Purezza:98%Colore e forma:SolidPeso molecolare:501.49BI-1230
CAS:BI-1230 is a potent inhibitor of HCV NS3 protease, exhibiting efficacy in the low nanomolar range, and notably suppresses viral replication.Formula:C42H52N6O9SPurezza:98%Colore e forma:SolidPeso molecolare:816.96TP0628103 TFA
CAS:TP0628103 (Compound 18) TFA is a selective MMP-7 inhibitor with an IC50 value of 0.17 nM, playing a significant role in cancer and fibrosis.Formula:C53H68ClF6N11O13SColore e forma:SolidPeso molecolare:1248.68Acetyl-Calpastatin (184-210)(human) acetate
<p>Acetyl-Calpastatin acetate inhibits µ-calpain (Ki=0.2nM) and cathepsin L (Ki=6μM) selectively and reversibly.</p>Formula:C144H234N36O46SPurezza:97.84% - 98.16%Colore e forma:SolidPeso molecolare:3237.68Calpain Inhibitor-1
CAS:Calpain Inhibitor-1, a potent Calpain 1 blocker, has IC50 of 100 nM and Ki of 2.89 μM.Formula:C19H17FN6O5SColore e forma:SolidPeso molecolare:460.44HIV-1 inhibitor-6
CAS:HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicingFormula:C14H10N4O4SPurezza:99.33%Colore e forma:SolidPeso molecolare:330.32Ref: TM-T9854
1mg75,00€5mg169,00€10mg284,00€25mg452,00€50mg645,00€100mg867,00€500mgPrezzo su richiestamidesteine
CAS:Midesteine (MR-889) is a small molecule neutrophil elastase inhibitor used in the treatment of bronchitis, asthma and chronic lung disease.Formula:C12H13NO3S3Purezza:99.87% - 99.98%Colore e forma:SolidPeso molecolare:315.43Patamostat HCl
CAS:Patamostat HCl is a highly potent and selective small molecule protease (protease) inhibitor that inhibits trypsin, fibrinolytic enzymes, and thrombin with IC50Formula:C20H21ClN4O4SPurezza:97.12% - 99.15%Colore e forma:SoildPeso molecolare:448.92Berotralstat
CAS:Berotralstat (BCX7353) is an oral, low-toxicity, specific kallikrein inhibitor for hereditary angioedema research, blocking bradykinin release.Formula:C30H26F4N6OColore e forma:SolidPeso molecolare:562.56EP 171
CAS:EP 171 is a potent agonist of TP-receptors.Formula:C23H29FO5Colore e forma:SolidPeso molecolare:404.47Knob A peptide GPRPFPAC
CAS:Knob A peptide GPRPFPAC is a fibrin knob peptide. The PEGylated form of Knob A peptide GPRPFPAC exhibits enhanced anticoagulant activity.Formula:C38H57N11O9SColore e forma:SolidPeso molecolare:843.99Activated Protein C (390-404), human
CAS:Human Activated Protein C (390-404) peptide derived from serine protease, suppresses APC anticoagulation.Formula:C91H130N22O23Purezza:98%Colore e forma:SolidPeso molecolare:1900.14PR 39 (porcine) acetate
PR 39 (porcine) acetate is a noncompetitive, reversible and allosteric proteasome inhibitor.Purezza:98%Colore e forma:LiquidPeso molecolare:N/ACepeginterferon alfa-2b
CAS:Cepeginterferon alfa-2b: pegylated interferon with 20 kDa PEG for HCV, PV, ET research.Colore e forma:LiquidNeutrophil elastase inhibitor 4
Neutrophil elastase inhibitor 4 (compound 4f) is a competitive inhibitor of human neutrophil elastase (HNE) with IC50 of 42.30 nM and Ki of 8.04 nM.Formula:C20H21N3O5Colore e forma:SolidPeso molecolare:383.4[Asp371]-Tyrosinase (369-377), human
CAS:Tyrosinase (369-377,YMDGTMSQV) originates from tyrosinase and needs TAP and proteosome for cell presentation.Formula:C42H66N10O16S2Purezza:98%Colore e forma:SolidPeso molecolare:1031.16FN-439 TFA
FN-439 TFA is a selective inhibitor of collagenase-1, exhibiting inhibition with an IC50 of 1 μM, and is utilized in cancer and inflammation research [1] [2].Formula:C25H35F3N6O8Purezza:98%Colore e forma:SolidPeso molecolare:604.58Obtusifolin-2-O-glucoside
CAS:Obtusifolin-2-O-glucoside (compound 7), a tyrosinase inhibitor with an IC50 value of 9.2 μM, can be isolated from cassia seed [1].Formula:C22H22O10Colore e forma:SolidPeso molecolare:446.4Histatin 5 (TFA)(115966-68-2,free)
Histatin 5 (TFA)(115966-68-2,free) (Histatin 5 (TFA)) inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μMFormula:C135H196F3N51O35Purezza:98%Colore e forma:SolidPeso molecolare:3150.32TP0597850
CAS:TP0597850, a selective MMP2 inhibitor with an IC50 value of 0.22 nM, demonstrates a prolonged dissociation half-life from MMP2 (t1/2 = 265 minutes) [1].Formula:C41H57N9O13SColore e forma:SolidPeso molecolare:916.016-Acetylnimbandiol
CAS:6-Acetylnimbandiol, a non-toxic agent, inhibits tyrosinase (IC50=69.85 μM), melanin, and MITF; useful in melanoma studies.Formula:C28H34O8Colore e forma:SolidPeso molecolare:498.56Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2
CAS:Ac-[Nle4,D-Phe7]-α-MSH (4-10)-NH2, a melanotropin derivative and melanocyte-stimulating hormone, activates tyrosinase and demonstrates a thermoregulatory effectFormula:C47H64N14O10Colore e forma:SolidPeso molecolare:985.1α 1(I) Collagen (614-639), human
CAS:This is a peptide inhibitor of collagen fibrillar matrix assembly.Formula:C134H189N37O39Purezza:98%Colore e forma:SolidPeso molecolare:2942.16Ac-AAVALLPAVLLALLAP-DEVD-CHO
CAS:Ac-AAVALLPAVLLALLAP-DEVD-CHO (DEVD-CHO-CPP 32) serves as a potent and reversible inhibitor of caspase-3 [1].Formula:C94H158N20O27Purezza:98%Colore e forma:SolidPeso molecolare:2000.38BMS-767778
CAS:BMS-767778, a DPP-4 inhibitor, is used potentially for the treatment of type 2 diabetes.Formula:C19H20Cl2N4O2Colore e forma:SolidPeso molecolare:407.29Mk-6186 HCl
MK-6186 HCl, a novel non-nucleoside reverse transcriptase inhibitor with antiviral activity, can be used to study HIV.Formula:C21H13Cl3N6OPurezza:97.04%Colore e forma:SoildPeso molecolare:471.73Tyrosinase-IN-38
Tyrosinase-IN-38 (compound 6b) is a competitive inhibitor of tyrosinase, demonstrating an IC50 of 25.82 μM and exhibits antioxidant activity.Colore e forma:Odour SolidC-telopeptide TFA
C-telopeptide TFA is a cross-linked peptide of type I collagen, released during bone resorption, and is associated with bone mineral density (BMD).Colore e forma:Odour SolidHIV-1 protease-IN-14
HIV-1protease-IN-14 (compound 5ae) is an effective inhibitor of HIV-1protease, exhibiting Ki values of 0.28 nM and 56.9 nM against WTHIV-1PR and R41THIV-1PR, respectively. This compound also demonstrates low cytotoxicity.Colore e forma:Odour Solid4-Epianhydrochlortetracycline (hydrochloride)
CAS:4-Epianhydrochlortetracycline (hydrochloride) can be used in related research in the field of life sciences.Formula:C22H22Cl2N2O7Colore e forma:SolidPeso molecolare:497.33PROTAC 20S proteasome subunit β5 degrader 2
PROTAC 20S proteasome subunit β5 degrader 2 is a PROTAC degrader targeting the 20S proteasome subunit β5 (20Sproteasomesubunit β5), with a DC50 of 0.16 μM. It inhibits the proliferation of FaDu cancer cells, showcasing an IC50 of 0.23 μM. Additionally, PROTAC20Sproteasomesubunit β5 degrader 2 demonstrates antitumor activity in a mouse model.Colore e forma:Odour SolidDiaminopropionoyl tripeptide-33
CAS:Diaminopropionoyl Tripeptide-33 is a bioactive peptide that safeguards skin cells against UVA-induced DNA damage and is utilized as a cosmetic ingredient [1].Formula:C17H27N7O6Purezza:98%Colore e forma:SolidPeso molecolare:425.44ADAM8-IN-1
CAS:<p>ADAM8-IN-1 is a potent ADAM8 inhibitor with an IC 50 value of 73 nM.</p>Formula:C44H44Br4N6O12S2Colore e forma:SolidPeso molecolare:1232.6β5i-IN-1
β5i-IN-1 is a selective inhibitor of β5i, exhibiting potent activity with an IC50 of 8.463 nM.Purezza:98%Colore e forma:Odour SolidH-Gly-Pro-Hyp-OH
CAS:H-Gly-Pro-Hyp-OH is a potent and oral anti-photoaging collagen peptide and improves the hydration of human skin, elasticity and anti-wrinkle properties.Formula:C12H19N3O5Purezza:98.47%Colore e forma:SolidPeso molecolare:285.3Clathrin-IN-1
CAS:<p>Pitstop 2 inhibits clathrin-mediated endocytosis, targeting clathrin's terminal domain, with potential in cancer research.</p>Formula:C20H13BrN2O3S2Purezza:99.53%Colore e forma:SolidPeso molecolare:473.36Fluostatin B
CAS:Fluostatin B, a fluorenone discovered in Streptomyces, is an inhibitor of dipeptidyl peptidase 3 (DPP-3; IC50= 24 µg/ml).Formula:C18H14O6Colore e forma:SolidPeso molecolare:326.3Pseudostellarin G
CAS:Pseudostellarin G, a naturally occurring cyclo-octapeptide, exhibits inhibitory activity against tyrosinase and suppresses melanin production.Formula:C42H56N8O9Colore e forma:SolidPeso molecolare:816.94Z-Leu-Tyr-Chloromethylketone
CAS:Z-Leu-Tyr-Chloromethylketone is a calpain inhibitor [1].Formula:C24H29ClN2O5Colore e forma:SolidPeso molecolare:460.95Ala-Phe-Pro-pNA TFA
Ala-Phe-Pro-pNA TFA serves as a chromogenic substrate for tripeptidyl peptidase and can be utilized to assess the enzyme's activity.Colore e forma:Odour SolidAMG-222
CAS:AMG-222 (ALS-2-0426, ALS-20426) is a DPP-4 inhibitor and may be used in the treatment of type 2 diabetes.Formula:C32H39N9O3Colore e forma:SolidPeso molecolare:597.71Fotagliptin
CAS:Fotagliptin is a dipeptidyl peptidase IV inhibitor.Formula:C17H19FN6OColore e forma:SolidPeso molecolare:342.37VPLSLYSG
CAS:<p>VPLSLYSG, an octapeptide, degraded by MMP-9, MMP-1, MMP-2; potential MMP substrate uses.</p>Formula:C39H62N8O12Colore e forma:SolidPeso molecolare:834.96SFTI-1
CAS:SFTI-1, a cyclic peptide trypsin inhibitor comprising 14 amino acid residues, is a potent Bowman-Birk inhibitor.Formula:C67H104N18O18S2Colore e forma:SolidPeso molecolare:1513.78Z-Arg-Arg-βNA acetate
CAS:Z-Arg-Arg-βNA acetate serves as a sensitive dipeptide substrate for Cathepsin B protease, while demonstrating resistance to proteases H and L. This compound is crucial for differentiating non-Cathepsin B type proteins.Formula:C32H43N9O6Colore e forma:SolidPeso molecolare:649.74Tilpisertib fosmecarbil TFA
CAS:Tilpisertib fosmecarbil TFA, the TFA salt form of Tilpisertib, acts as an inhibitor of serine/threonine kinases. This compound also exhibits anti-inflammatory activity.Formula:C37H37ClF3N8O9PColore e forma:SolidPeso molecolare:861.16HCV-IN-41
CAS:HCV-IN-41: potent HCV inhibitor; EC50 - 0.006762 nM (1b), 5.183 nM (2a), 1.365 nM (3a), 142.2 nM (4a); hinders RNA replication.Formula:C48H56N6O8Colore e forma:SolidPeso molecolare:844.99Tyrosinase-IN-34
Tyrosinase-IN-34 (compound 5a), a human tyrosinase inhibitor (IC 50: 3.5 μM), shows promise in regulating melanogenesis and pigmentation.Formula:C19H14BrClN4OColore e forma:SolidPeso molecolare:429.77-Methoxy obtusifolin
CAS:7-Methoxy obtusifolin (Compound 4) is a chemical compound that acts as a competitive inhibitor of the enzyme tyrosinase, displaying an inhibitory concentrationFormula:C17H14O6Colore e forma:SolidPeso molecolare:314.292-Hydroxy-4-methoxybenzoic acid potassium
CAS:2-Hydroxy-4-methoxybenzoic acid potassium (4-Methoxysalicylic acid potassium) is a principal component of the [plant], exhibiting multiple biological effects that include anti-inflammatory, antipyretic, antioxidative, and antidiabetic properties.Formula:C8H7KO4Colore e forma:SolidPeso molecolare:206.24PPACK II
CAS:PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor [1] .Formula:C25H33ClN6O3Colore e forma:SolidPeso molecolare:501.02Idarucizumab
CAS:Idarucizumab, a humanized monoclonal antibody fragment, serves as the first reversal agent for direct oral anticoagulants (DOACs).Colore e forma:LiquidAcetyl-Calpastatin(184-210)(human), Negative Control
Acetyl-Calpastatin(184-210)(human), Negative Control is a control scrambled peptide corresponding to Acetyl-Calpastatin(184-210)(human). Acetyl-Calpastatin(184-210)(human) functions as a potent, selective, and reversible calpain inhibitor.Formula:C142H230N36O44SPeso molecolare:3175.65874Adamtsostatin 18
CAS:Adamtsostatin 18, an anti-angiogenic peptide derived from proteins with type I thrombospondin motifs, suppresses cell migration and proliferation [1].Formula:C89H141N29O29S2Peso molecolare:2145.38Tyrosinase-IN-21
Tyrosinase-IN-21 (compound 3g) is a tyrosinase inhibitor with an IC50 value of 80.93 μM.Formula:C23H20N4O3S2Peso molecolare:464.09768MeOSuc-AAPF-CMK
CAS:MeOSuc-AAPF-CMK (MeOSuc-Ala-Ala-Pro-Phe-CH2Cl) is a potent inhibitor of the enzyme proteinase K [1].Formula:C26H35ClN4O7Peso molecolare:551.03STK33-IN-1
CAS:STK33-IN-1 (compound 1) is a STK33 inhibitor, with an IC 50 of 7 nM.Formula:C24H27N7O2Colore e forma:SolidPeso molecolare:445.527Relacatib
CAS:Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.Formula:C27H32N4O6SColore e forma:SolidPeso molecolare:540.64HB-2-30
CAS:HB-2-30 is a far-red fluorescent transglutaminase 2 (TG2) probe for in vitro and in vivo endocytosis imaging. HB-2-30 complexes with TG2 and α2-macroglobulin for efficient endocytosis via the LRP1 pathway.Formula:C66H86N10O14S2Peso molecolare:1307.58Cathepsin K inhibitor 7
Cathepsin K Inhibitor7 (compound 7) is an inhibitor of Cathepsin K, exhibiting a pKi value of 7.3. It is utilized in research on osteoporosis.Colore e forma:Odour SolidHCV-IN-7 hydrochloride
CAS:HCV-IN-7 hydrochloride: Oral, potent HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.Formula:C40H50Cl2N8O6SPurezza:98%Colore e forma:SolidPeso molecolare:841.85Lonodelestat TFA
Lonodelestat TFA, an oral peptide, selectively inhibits hNE, potentially aiding in CF research.Formula:C73H112F3N15O21Colore e forma:SolidPeso molecolare:1592.75Roseltide rT1
CAS:Roseltide rT1 is a neutrophil elastase inhibitor (IC50=0.47 μM) and is rich in cysteine, classified as one of the Roseltides (rT1-rT8). It has the potential to inhibit related diseases by improving neutrophil elastase-stimulated cAMP accumulation in vitro.Formula:C110H177N31O31S6Colore e forma:SolidPeso molecolare:2622.16HCV-IN-47
CAS:Compound PDK0173, with CAS No. 300543-56-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0173 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C17H19ClN2Peso molecolare:286.79GSK2818713
CAS:GSK2818713 is a novel Hepatitis C NS5A replication complex inhibitor.Formula:C46H56N8O8Colore e forma:SolidPeso molecolare:849.002Thrombin inhibitor 13
Thrombin inhibitor 13 (Compound 13a) acts as a covalent reversible inhibitor of thrombin (thrombin, FIIa) with an IC50 of 0.7 nM. This compound prolongs activated partial thromboplastin time (aPTT) and prothrombin time (PT), demonstrating both antithrombotic and anticoagulant properties.Formula:C16H17ClN6OSColore e forma:SolidPeso molecolare:376.864Atecegatran TFA
CAS:Atecegatran TFA is often used as an anticoagulant and can be used to treat cardiovascular disease.Formula:C23H22ClF5N4O6Purezza:97.47% - 99.77%Colore e forma:SolidPeso molecolare:580.89PSI-353661
CAS:PSI-353661 (GS-558093), inhibits HCV's NS5B polymerase; EC90: 8nM (wild-type), 11nM (S282T); active in human hepatocytes.Formula:C24H32FN6O8PColore e forma:SolidPeso molecolare:582.52Ichorcumab
CAS:<p>Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.</p>Colore e forma:LiquidMMP-9/MMP-13 Inhibitor I
CAS:MMP-9/MMP-13 Inhibitor I is a dual inhibitor of MMP-9 and MMP-13 with IC50 of both 0.9 nM.Formula:C25H25N3O6SColore e forma:SolidPeso molecolare:495.55Tyrosinase-IN-40
Tyrosinase-IN-40 (Compound 9r) is a competitive inhibitor of tyrosinase, boasting an IC50 value of 17.02 µM and a Ki value of 14.87 µM. This compound also exhibits antioxidant activity and can be utilized in studies related to melanin.Formula:C34H29N9O10Colore e forma:SolidPeso molecolare:723.648HIV-1 Rev (34-50)
CAS:HIV-1 Rev (34-50) (HIV-1 rev Protein (34-50)) is a 17 amino acid peptide with anti-HIV-1 activity.Formula:C97H173N51O24Purezza:99.91%Colore e forma:SolidPeso molecolare:2437.74Ac-AAVALLPAVLLALLAP-YVAD-CHO
CAS:Ac-AAVALLPAVLLALLAP-YVAD-CHO is a cell-permeable inhibitor of caspase-1 exhibiting antitumor activity [1].Formula:C97H160N20O24Purezza:98%Colore e forma:SolidPeso molecolare:1990.43APC-6860
CAS:APC-6860, a serine protease inhibitor, targets multiple enzymes; most potent against human urokinase (Ki: 0.1 µM). Used in cancer research.Formula:C9H7IN2SColore e forma:SolidPeso molecolare:302.13PS 915
CAS:PS 915 is a substrate for colorimetric assay. It was used for plasma antithrombin.Formula:C27H36ClN7O6Purezza:98%Colore e forma:SolidPeso molecolare:590.08Cathepsin D and E FRET Substrate
CAS:Mca-GKPILFFRL-Dpa-r-amide, FRET substrate for cathepsin D and E. Also cleaved by napsin A.Formula:C85H122N22O19Colore e forma:SolidPeso molecolare:1756.046KKI-5
CAS:<p>KKI 5: Serine protease inhibitor, blocks kallikrein & plasmin, potential for cancer therapy & angioedema treatment.</p>Formula:C35H55N11O9Purezza:98%Colore e forma:SolidPeso molecolare:773.88Histargin
CAS:Histargin is an enzyme inhibitor separated from Streptomyces roseoviridis.Formula:C14H25N7O4Colore e forma:SolidPeso molecolare:355.39Ac-VDQQD-pNA
CAS:Ac-VDQQD-pNA serves as a substrate for Caspase 2, which cleaves it to yield the yellow compound pNA (p-nitroaniline).Formula:C31H43N9O14Colore e forma:SolidPeso molecolare:765.73AL-611
CAS:<p>AL-611 is an HCV NS5B polymerase inhibitor ( EC 50 = 5 nM).</p>Formula:C25H33F2N6O8PColore e forma:SolidPeso molecolare:614.544C1 Esterase Inhibitor (Human)
C1 Esterase Inhibitor (Human) is a glycoprotein derived from human plasma and acts as a serine protease inhibitor. It inactivates enzymes like C1r, C1s, and mannose-binding lectin-associated serine proteases (MASP) through covalent binding. This compound possesses anti-inflammatory properties and is utilized to prevent angioedema attacks associated with hereditary angioedema.Colore e forma:Odour LiquidEllipyrone B
Ellipyrone B, a γ-pyrone-based macrocyclic polyketide with antihyperglycemic properties, demonstrates inhibitory activity against dipeptidyl peptidase-4 (IC 50Formula:C25H38O7Colore e forma:SolidPeso molecolare:450.57Fluostatin A sodium
CAS:Fluostatin A, a fluorenone compound initially isolated from Streptomyces, demonstrates selective inhibition towards dipeptidyl peptidase 3 (DPP-3) compared toFormula:C18H9O5·NaColore e forma:SolidPeso molecolare:328.25Sitagliptin fenilalanil hydrochloride
CAS:Sitagliptin phenylalanine hydrochloride, a dipeptidyl peptidase-4 (DPP-4) inhibitor [1], is a chemical compound utilized in medical applications.Formula:C25H25ClF6N6O2Colore e forma:SolidPeso molecolare:590.95Cathepsin D and E FRET Substrate acetate(839730-93-7 Free base)
Fluorogenic substrate for cathepsins D & E; cleaves at Phe-Phe bond; not for B, H, L. Useful for assays and studies.Colore e forma:Odour SolidSuc-AAP-Abu-pNA
CAS:Suc-AAP-Abu-pNA is a specific substrate for pancreatic elastase (Km = 100 μM; Kcat/Km = 35,300 s-1 M-1 for rat pancreatic elastase; Km = 30 μM; Kcat/Km = 351,Formula:C25H34N6O9Colore e forma:SolidPeso molecolare:562.57Ecallantide TFA
Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention ofColore e forma:Odour SolidGCPII-IN-1
CAS:<p>GCPII-IN-1, a potent PSMA inhibitor, binds with 44.3 nM affinity.</p>Formula:C12H21N3O7Colore e forma:SolidPeso molecolare:319.314Stevia Powder
Stevia Powder, a natural sweetener, possesses antioxidant properties. It regulates antifibrotic pathways in cirrhotic rats, demonstrated by a reduction in hepatic stellate cells and decreased expression of matrix metalloproteinases MMP2 and MMP13. Furthermore, it increases the antifibrotic molecule Smad7, which helps prevent the elevation of serum necrosis and bile retention markers, thereby inhibiting the progression of liver fibrosis.Colore e forma:Odour SolidDansyl-Glu-Gly-Arg-Chloromethylketone
CAS:Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor that specifically impedes serine/threonine proteases and has been shown to inhibit activatedFormula:C26H36ClN7O7SColore e forma:SolidPeso molecolare:626.12Marstacimab
CAS:Marstacimab (PF-06741086), an anti-tissue factor pathway inhibitor (TFPI) monoclonal antibody, is utilized in hemophilia research [1] [2].Purezza:98.3% (SDS-PAGE); 99% (SEC-HPLC) - 98.3% (SDS-PAGE); 99% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:142.59 kDaHirudin (55-65) (sulfated)
CAS:Hirudin (55-65) (sulfated), a fragment of Hirudin, is a thrombin inhibitor with anticoagulant effects and blood anticoagulant properties.Formula:C64H90N12O27SColore e forma:SolidPeso molecolare:1491.53MMP-2 Inhibitor-4
MMP-2Inhibitor-4 (Compound 5g) is an MMP-2 inhibitor with an IC50 of 152.62 nM. It effectively reduces MMP-2 levels in K562 cell lines by stably binding to the active site of MMP-2 and exhibits strong anti-angiogenic effects in ACHN cell lines. MMP-2Inhibitor-4 shows potential for research in chronic myelogenous leukemia (CML).Formula:C19H23N3O5SColore e forma:SolidPeso molecolare:405.468VAMP
<p>VAMP is a tetrapeptide that acts as a competitive dipeptidyl peptidase IV (DPP-IV) inhibitor, exhibiting an IC50 of 1.00 μM and a Kd of 6.89 μM. It effectively targets the DPP-IV-GLP-1 axis and is utilized in the research of type 2 diabetes.</p>Formula:C18H32N4O5SColore e forma:SolidPeso molecolare:416.535Thrombin receptor peptide ligand
CAS:Thrombin receptor peptide ligand, a thrombin receptor antagonist, serves as an antithrombotic agent [1].Formula:C33H54N10O8Purezza:98%Colore e forma:SolidPeso molecolare:718.84Alisporivir
CAS:Alisporivir (Debio-025) is a cyclophilin A inhibitor that disrupts the interaction between CypA and NS5A. HCV activity in vivo and in vitro.Formula:C63H113N11O12Purezza:99.95%Colore e forma:SolidPeso molecolare:1216.64Cathepsin L-IN-3
CAS:Cathepsin L-IN-3, a tripeptide-sized inhibitor of cathepsin L, effectively targets this specific enzyme.Formula:C41H49N7O4SColore e forma:SolidPeso molecolare:735.94Histatin 5 TFA
Histatin 5 TFA effectively inhibits host matrix metalloproteinases (MMP-2) and (MMP-9), demonstrating inhibition concentrations (IC 50s) of 0.57 μM and 0.25 μMFormula:C135H196N51F3O35Colore e forma:SolidPeso molecolare:3150.31NIM811
CAS:NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.Formula:C62H111N11O12Purezza:98%Colore e forma:SolidPeso molecolare:1202.635Tyrosinase-IN-36
Tyrosinase-IN-36 is a moderately potent inhibitor of tyrosine, exhibiting an inhibition percentage of 42.75% compared to kojic acid at a concentration of 100 μM and possesses antioxidant activity.Colore e forma:Odour SolidChetoseminudin B
CAS:Chetoseminudin B exhibits inhibitory activity against mushroom tyrosinase, with an IC 50 value of 31.7 μM [1].Formula:C17H21N3O3S2Colore e forma:SolidPeso molecolare:379.5TR-107
CAS:TR-107 (Anticancer agent 230) is a mitochondrial protease ClpP activator that inhibits tumor growth in the MDA-MB-231 xenograft model.Formula:C22H19ClN4OColore e forma:SoildPeso molecolare:390.87NVP-DPP728 dihydrochloride
CAS:NVP-DPP728 dihydrochloride is a potent, selective DPP-IV inhibitor with a Ki of 11 nM, useful in diabetes research.Formula:C15H20Cl2N6OColore e forma:SolidPeso molecolare:371.27Recombinant Proteinase K
Recombinant Proteinase K: serine protease, cleaves carboxy-terminus peptides, digests proteins, purifies nucleic acids.Colore e forma:SolidRivulariapeptolides 1121
Rivulariapeptolides 1121 inhibits serine proteases: chymotrypsin (IC50=35.52 nM), elastase (13.24 nM), proteinase K (48.05 nM).Formula:C56H83N9O15Colore e forma:SolidPeso molecolare:1122.31RXP470
CAS:RXP470 is a potent and selective MMP-12 inhibitor (Ki 0.24 nM).Formula:C35H35BrClN4O10PColore e forma:SolidPeso molecolare:818VD2173
CAS:<p>VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.</p>Formula:C31H45N9O6SColore e forma:SolidPeso molecolare:671.815-epi-Arvestonate A
CAS:<p>5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.</p>Formula:C16H26O5Colore e forma:SolidPeso molecolare:298.37Sofosbuvir impurity M
CAS:Sofosbuvir impurity M is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.Formula:C22H30N3O10PPurezza:98%Colore e forma:SolidPeso molecolare:527.467TNO211
CAS:TNO211 is a bioactive peptide that functions as a highly soluble fluorogenic substrate for select Matrix Metalloproteinases (MMPs)—specifically MMP-2, 8, 12, 13Formula:C63H88N16O14SPurezza:98%Colore e forma:SolidPeso molecolare:1325.54Tyrosinase-IN-32
Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.Formula:C15H19NO3Colore e forma:SolidPeso molecolare:261.32RJS308
<p>RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)</p>Formula:C63H75N13O11SColore e forma:SolidPeso molecolare:1222.42LM11
<p>LM11 is a transglutaminase 2 (TG2) inhibitor that exhibits activity against glioblastoma cells by maintaining TG2 in a cytotoxic conformational state.</p>Formula:C26H18Cl2N4O5Peso molecolare:536.06543Cerpegin
CAS:Cerpegin, a pyridine ketone fused c-lactone, acts as an inhibitor of the 20S proteasome. It possesses pharmacological properties as a neuropsychiatric sedative, anti-inflammatory, analgesic, and exhibits anti-ulcer activity.Formula:C10H11NO3Colore e forma:SolidPeso molecolare:193.2N-CBZ-Phe-Arg-AMC
CAS:Z-FR-AMC substrate for serine proteases; cathepsins, kallikrein, plasmin. Substrate: 330/390 nm; Product: 342/441 nm.Formula:C33H36N6O6Purezza:98%Colore e forma:White To Off-White PowderPeso molecolare:612.68PROTAC CG167
PROTAC CG167 is a potent and selective PROTAC degrader of CypA. It degrades CypA in a dose-dependent manner in Jurkat cells, with a DC50 of 123 nM. Additionally, PROTAC CG167 exhibits antiviral activity by inhibiting HIV-1 and HCV. (Pink: CypA Ligand; Black: Linker; Blue: E3LigaseLigand)Formula:C65H79N13O11SColore e forma:SolidPeso molecolare:1250.47Talabostat isomer mesylate
Talabostat isomer mesylate, a PT100/Val-boroPro variant, is a potent oral DPP-IV inhibitor (Ki: 0.18 nM).Formula:C10H23BN2O6SPurezza:98%Colore e forma:SolidPeso molecolare:310.18L 659286
CAS:L 659286 is one kind of cephalosporin derivative.Formula:C17H21N5O7S2Colore e forma:SolidPeso molecolare:471.51Acetyl-Calpastatin(184-210)(human)
CAS:Calpain inhibitor, Ki 0.2 nM for calpain I/II, doesn't affect papain/trypsin/cat L. Raises Aβ42, Aβ40 secretion & Aβ42/Aβ40 ratio.Formula:C142H230N36O44SPurezza:98%Colore e forma:SolidPeso molecolare:3177.65Acetyl-Hirudin (54-65) (sulfated)
CAS:Acetyl-Hirudin (54-65) (sulfated) binds thrombin-rHCII(L444R), blocking rHCII's N-terminal/thrombin exosite I interaction, stabilizing the complex.Formula:C68H95N13O29SColore e forma:SolidPeso molecolare:1590.63Ellipyrone A
Ellipyrone A: γ-pyrone macrocycle, inhibits DPP-4 (IC50=0.35mM), α-glucosidase (IC50=0.74mM), α-amylase (IC50=0.59mM).Formula:C25H34O8Colore e forma:SolidPeso molecolare:462.53Leptosin D
CAS:Leptosin D, a thiodiketopiperazine alkaloid derived from mushrooms, effectively inhibits tyrosinase activity, demonstrating an inhibition concentration (IC50)Formula:C25H24N4O3S2Colore e forma:SolidPeso molecolare:492.61LXE408 fumarate
<p>LXE408 fumarate: orally available, selective kinetoplastid proteasome inhibitor with IC50/EC50 of 0.04 μM for L. donovani; potentially aids in VL research.</p>Formula:C27H22FN7O6Purezza:99.89%Colore e forma:SoildPeso molecolare:559.51Talabostat
CAS:Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM.Formula:C9H19BN2O3Colore e forma:SolidPeso molecolare:214.07Carboxypeptidase C
CAS:Carboxypeptidase C removes COOH-terminal amino acids and others in peptides for biochemical studies.Colore e forma:SolidTrivalent hydroxyarsinothricn
Trivalent hydroxyarsinothricn (R-AST-OH) is a covalent and irreversible inhibitor of kidney-type glutaminase (KGA). It binds to the glutamine binding site and forms a covalent bond with the cysteine residue at the active site. This compound selectively kills triple-negative breast cancer (TNBC) cells without being cytotoxic to control cell lines. KGA is an enzyme that regulates glutamine metabolism and is associated with tumor malignancy.Formula:C4H10AsNO4Peso molecolare:210.98258Emtricitabine S-oxide
CAS:Emtricitabine treats HIV; its degradation byproduct is Emtricitabine S-oxide.Formula:C8H10FN3O4SPurezza:98%Colore e forma:SolidPeso molecolare:263.25CL 82198 hydrochloride
CAS:CL 82198 hydrochloride selectively inhibits MMP-13, not MMP-1/9/TACE, and blocks HP75 invasion and neurotoxicity in zebrafish.Formula:C17H23ClN2O3Colore e forma:SolidPeso molecolare:338.83Enzyme-IN-1
CAS:Enzyme-IN-1（compound 1）为基于肽的N端亲核试剂（Ntn）水解酶抑制剂，特别针对20S蛋白酶体的糜胰蛋白酶样活性（CT-L）进行抑制，可能展现出抗炎特性。Formula:C36H50N4O7Colore e forma:SolidPeso molecolare:650.8CRA-2059 hydrochloride
CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2].Colore e forma:SolidIETD-CHO TFA
IETD-CHO TFA (Caspase-8-IN-1) functions as a potent inhibitor of caspase-8 [1].Formula:C95H162N20O26·xC2HF3O2Purezza:98%Colore e forma:SolidPeso molecolare:2000.42 (free acid)Ac-PAL-AMC
CAS:Ac-PAL-AMC is a β1i/LMP2-specific substrate that fluoresces when cleaved; useful for measuring immunoproteasome activity.Formula:C26H34N4O6Colore e forma:SolidPeso molecolare:498.576,6′-Dihydroxythiobinupharidine
CAS:6,6′-Dihydroxythiobinupharidine, a cysteine proteases inhibitor, amplifies DNA cleavage facilitated by human topoisomerase IIα and IIβ by approximately 8-foldFormula:C30H42N2O4SColore e forma:SolidPeso molecolare:526.73Bortezomib analog
Bortezomibanalog (Compound 13) is an analog of Bortezomib, functioning as an active control ligand for the 20S proteasome subunit β5.Colore e forma:Odour SolidGrazoprevir potassium salt
CAS:<p>Grazoprevir, a drug for hepatitis C, is a second-gen NS3/4a protease inhibitor.</p>Formula:C38H49KN6O9SColore e forma:SolidPeso molecolare:805Rivulariapeptolides 1185
Rivulariapeptolides 1185 inhibits serine proteases; IC50: chymotrypsin 13.17 nM, elastase 23.59 nM, proteinase K 55.26 nM.Formula:C61H87N9O15Colore e forma:SolidPeso molecolare:1186.39Fotagliptin benzoate
CAS:Fotagliptin benzoate, a DPP-4 inhibitor (IC50=2.27 nM), is safe in rats/dogs, useful for Type 2 diabetes research.Formula:C24H25FN6O3Colore e forma:SolidPeso molecolare:464.4915,16-Dihydrotanshindiol C
15,16-Dihydrotanshindiol C is a useful organic compound for research related to life sciences and the catalog number is T123985.Formula:C18H18O5Colore e forma:SolidPeso molecolare:314.337FiVe1
CAS:<p>FiVe1 is a vimentin-binding compound that disrupts mitosis in cancer cells, causing cell death, with an IC50 of 234 nM in FOXC2-HMLER.</p>Formula:C18H16Cl2N4Purezza:99.67%Colore e forma:SolidPeso molecolare:359.25AAF-CMK (trifluoroacetate salt)
CAS:TPPII, a serine peptidase, cleaves tripeptides from oligopeptides. AAF-CMK irreversibly inhibits TPPII at 10-100 μM, sparing proteasome activity.Formula:C18H23ClF3N3O5Colore e forma:SolidPeso molecolare:453.84Talopeptin
CAS:Talopeptin is a specific thermolysin inhibitor.Formula:C23H34N3O10PPurezza:98%Colore e forma:SolidPeso molecolare:543.50NS5A-IN-4
CAS:NS5A-IN-4 (Compound 1.12) is a hepatitis C inhibitor effective against multiple genotypes, with IC50 values ranging from 1.2 to 2296 pM.Formula:C47H48N8O6Colore e forma:SolidPeso molecolare:820.93Tyrosinase/elastase-IN-1
Tyrosinase/elastase-IN-1, a triterpenoid extracted from the leaves of Rubus fraxinifolius, exhibits inhibitory activities against both tyrosinase and elastaseFormula:C33H52O5Colore e forma:SolidPeso molecolare:528.76MMP-9-IN-6
CAS:MMP-9-IN-6: MMP-9 inhibitor, IC50 of 50 µM, anti-ulcer, potential anti-tumor, for tissue repair studies.Formula:C25H19NO2Purezza:98.96%Colore e forma:SoildPeso molecolare:365.42α 1 Antichymotrypsin, Human Plasma
CAS:Alpha 1 Antichymotrypsin, Human Plasma is an inhibitor of serine proteases. This compound is present in amyloid lesions associated with Alzheimer's disease and can be utilized in Alzheimer's research.Colore e forma:SolidRadalbuvir
CAS:Radalbuvir (GS-9669) is an investigational antiviral agent for the treatment of hepatitis C virus (HCV) infection as an NS5B inhibitor.Formula:C30H41NO6SColore e forma:SolidPeso molecolare:543.71OM-7D3-B3
OM-7D3-B3 is a monoclonal antibody that targets human tight junction protein 1 (CLDN1) with a dissociation constant (Kd) of 4 nM. This antibody inhibits the role of CLDN1 in the cellular entry of the hepatitis C virus (HCV) and holds potential for research into HCV infection.Sulodexide
CAS:Sulodexide is an orally administered combination of glycosaminoglycans, consisting of low molecular weight heparin (80%) and dermatan sulfate (20%). It demonstrates antithrombotic properties by interacting with antithrombin III (AT III) and heparin cofactor II (HC II), and by inhibiting thrombin formation. Additionally, sulodexide enhances profibrinolytic activity by releasing tissue plasminogen activator (tPA). It also offers endothelial protection, possesses anti-inflammatory effects, and alleviates chronic venous disease.Colore e forma:SolidLMP7/LMP2-IN-1
CAS:LMP7/LMP2-IN-1 (Compound 19) is an orally effective inhibitor targeting the immunoproteasome subunits LMP7 and LMP2, with respective IC50 values of 257 and 10 nM. This compound reduces the production of antibodies and downregulates the B cells in the germinal centers of the spleen and plasma cells in NP-OVA immunized mice. It has potential applications in the study of autoimmune diseases.Formula:C16H27BN4O3Colore e forma:SoildPeso molecolare:334.22Chymotrypsinogen
CAS:Chymotrypsinogen is an inactive precursor of Chymotrypsin . Chymotrypsin is a serine protease produced by the pancreas [1] [2] .Colore e forma:SolidBictegravir Sodium
CAS:Bictegravir Sodium is an HIV-1 integrase inhibitor with 7.5 nM IC50, offering strong, selective anti-HIV effects and minimal toxicity.Formula:C21H17F3N3NaO5Purezza:99.97%Colore e forma:SolidPeso molecolare:471.36Sofosbuvir impurity L
Sofosbuvir impurity L is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.Formula:C22H29FN3O10PPurezza:98%Colore e forma:SolidPeso molecolare:545.45Phaeosphaone D
CAS:Phaeosphaone D, a thiodiketopiperazine from Phaeosphaeria fuckelii fungus, inhibits mushroom tyrosinase (IC50 = 33.2 μM).Formula:C20H27N3O3S2Colore e forma:SolidPeso molecolare:421.58MMP-3 Inhibitor
CAS:MMP-3 Inhibitor is a peptide matrix metalloproteinase-3 (MMP-3) inhibitor with a Ki value of 95 nM.MMP-3 inhibitor has anticancer and antitumor activity.Formula:C27H46N10O9SPurezza:98.87%Colore e forma:SolidPeso molecolare:686.78Ref: TM-T37048
1mg81,00€5mg208,00€10mg309,00€25mg525,00€50mg757,00€100mg1.035,00€500mg2.110,00€1mL*10mM (DMSO)221,00€HCV-IN-4
CAS:HCV-IN-4: Potent, oral HCV NS5A inhibitor; effective vs GT1a/b, GT2b, GT3a, Y93H, L31V; EC90s: 3 pM-0.02 nM.Formula:C52H58FN9O8Purezza:98%Colore e forma:SolidPeso molecolare:956.07Iso-VQA-ACC acetate
Iso-VQA-ACC acetate serves as a substrate for the constitutive proteasome.Colore e forma:Odour SolidDutogliptin tartrate
CAS:Dutogliptin tartrate is an effective and selective oral dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.Formula:C14H26BN3O9Purezza:98%Colore e forma:SolidPeso molecolare:391.18Sadopeptins B
Sadopeptins B, a natural product isolated from Streptomyces sp., is a potent proteasome inhibitor [1].Formula:C48H69N9O13SColore e forma:SolidPeso molecolare:1012.18NS5A-IN-1
NS5A-IN-1 is a proagent of the HCV NS5A inhibitor Pibrentasvir (ABT-530).Formula:C72H86F5N10O14PColore e forma:SolidPeso molecolare:1441.48JC-10
CAS:JC-10 is a potent inhibitor of metalloproteinases and is often used as a probe.Formula:C25H29Cl2IN4Purezza:95%Colore e forma:SolidPeso molecolare:583.34Sofigatran
CAS:Sofigatran (MCC-977) is an oral anticoagulant targeting thrombin for cardiovascular research.Formula:C24H44N4O4SColore e forma:SolidPeso molecolare:484.7Isoleucylvaline
CAS:Isoleucylvaline is a dipeptide.Formula:C11H22N2O3Colore e forma:SolidPeso molecolare:230.30Phosphorylase Kinase β-Subunit Fragment (420-436)
CAS:Phosphorylase Kinase β-Subunit Fragment (420-436) is a peptide fragment (430-436) derived from the β-Subunit of phosphorylase kinase.Formula:C79H131N31O25SPurezza:98%Colore e forma:SolidPeso molecolare:1947.14MMP-9-IN-7
CAS:N-[2-[(5-Cl-2-methoxyphenyl)amino]-4'-methyl[4,5'-bithiazol]-2'-yl]acetamide inhibits pro-MMP activation, treats MMP9/MMP13 syndromes.Formula:C16H15ClN4O2S2Purezza:97.65%Colore e forma:SolidPeso molecolare:394.9Ref: TM-T72069
1mg64,00€5mg131,00€10mg188,00€25mg325,00€50mg487,00€100mg708,00€500mg1.483,00€1mL*10mM (DMSO)131,00€FFAGLDD
"FFAGLDD: MMP9 peptide for controlled DOX delivery inside cells."Formula:C37H49N7O12Purezza:98%Colore e forma:SolidPeso molecolare:783.82PSI-7409
CAS:<p>PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977).</p>Formula:C10H16FN2O14P3Purezza:98%Colore e forma:SolidPeso molecolare:500.16Saxagliptin hydrochloride
CAS:Saxagliptin: oral DPP-4 inhibitor, enhances incretins, manages type 2 diabetes by reducing glucose levels.Formula:C18H26ClN3O2Colore e forma:SolidPeso molecolare:351.87Alogliptin (13CD3)
CAS:Alogliptin (SYR-322) 13CD3 is the deuterium-labeled Alogliptin. Alogliptin is a selective inhibitor of DPP-4.Formula:C18H21N5O2Purezza:98%Colore e forma:SolidPeso molecolare:343.4Tripeptide-32
CAS:Tripeptide-32 is a bioactive peptide recognized for its anti-aging properties, commonly utilized as an ingredient in cosmetics [1].Formula:C12H22N4O5Purezza:98%Colore e forma:SolidPeso molecolare:302.33E-64d [for Biochemical Research]
CAS:Formula:C17H30N2O5Purezza:>95.0%(HPLC)Colore e forma:White to Almost white powder to crystalPeso molecolare:342.44Ilomastat
CAS:Formula:C20H28N4O4Purezza:>95.0%(HPLC)(qNMR)Colore e forma:White to Light yellow powder to crystalPeso molecolare:388.47Thrombin inhibitor 5
CAS:Thrombin inhibitor 5 (compound 385), IC50: 0.1-1 μM, used in venous thromboembolism studies.Formula:C11H9FN4O3Purezza:99.58%Colore e forma:SolidPeso molecolare:264.21Ref: TM-T9845
2mg38,00€5mg59,00€10mg90,00€25mg162,00€50mg235,00€100mg339,00€200mg457,00€1mL*10mM (DMSO)58,00€CTS-1027
CAS:CTS-1027 is a small molecule inhibitor of MMPs (IC50s: 0.3 nM, 0.5 nM for MMP2, MMP13). It has > 1,000 fold selectivity over MMP1.Formula:C19H20ClNO6SColore e forma:SolidPeso molecolare:425.88Glutaminase-IN-3
CAS:Glutaminase-IN-3 is a potent Glutaminase 1 inhibitor with potential antitumor activity and inhibits GLS1 for cancer research.Formula:C19H19F3N6O2SPurezza:98.51%Colore e forma:SolidPeso molecolare:452.45Tenofovir hydrate
CAS:Tenofovir hydrate (GS 1278 hydrate) is a nucleotide reverse transcriptase inhibitor with antiviral activity.Formula:C9H16N5O5PPurezza:99.63%Colore e forma:SolidPeso molecolare:305.23Ubenimex Hydrochloride [for Biochemical Research]
CAS:Formula:C16H24N2O4·HClPurezza:>97.0%(HPLC)Colore e forma:White to Almost white powder to crystalPeso molecolare:344.84PSI-6206 13C,d3
CAS:<p>PSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is a potent and selective HCV NS5B polymerase inhibitor.</p>Formula:C10H13FN2O5Purezza:98%Colore e forma:SolidPeso molecolare:264.23LN5P45
LN5P45, an OTUB2 inhibitor (IC50: 2.3 μM), promotes monoubiquitination of OTUB2 at lysine 31 and is utilized in the study of tumor progression and metastasis [1Formula:C13H15ClN2O2Colore e forma:SolidPeso molecolare:266.726-Chloro-7-deazapurine-2F-β-D-arabinofuranose
CAS:6-Chloro-7-deazapurine-2F-β-D-arabinofuranose is a Nucleoside - 7-deazapurine nucleoside, fluoronucleoside, halo nucleoside; Arabino-nucleoside.Formula:C11H11ClFN3O3Colore e forma:SolidPeso molecolare:287.67Ref: TM-TNU0055
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiesta500mgPrezzo su richiestaDabigatran ethyl ester
CAS:Dabigatran ethyl ester (Dabigatran (ethyl ester)) is an emerging oral anticoagulant and it also is a direct inhibitor of thrombin activity.Formula:C27H29N7O3Purezza:99.98%Colore e forma:SolidPeso molecolare:499.56
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