Proteasi/Proteasoma
Gli inibitori delle proteasi e del proteasoma sono composti che bloccano l'attività delle proteasi e del proteasoma, che sono coinvolti nella degradazione e nel turnover delle proteine. Questi inibitori sono fondamentali per studiare la regolazione dell'omeostasi proteica, il controllo del ciclo cellulare e l'apoptosi. Gli inibitori delle proteasi e del proteasoma vengono anche utilizzati nel trattamento di malattie come il cancro, dove la degradazione anomala delle proteine svolge un ruolo nella progressione della malattia. Inibendo le proteasi o il proteasoma, questi composti possono indurre la morte cellulare nelle cellule tumorali e sono strumenti critici sia per la ricerca di base che per lo sviluppo terapeutico. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle proteasi e del proteasoma di alta qualità per supportare la tua ricerca in biochimica, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Proteasi/Proteasoma"
- Acetil-CoA carbossilasi(36 prodotti)
- Cisteina proteasi(110 prodotti)
- DPP-4(20 prodotti)
- Glutaminasi(45 prodotti)
- Proteasi HIV(506 prodotti)
- PAI-1(26 prodotti)
- Inibitori della proteasi(50 prodotti)
- Ricettore attivato dalla proteasi(54 prodotti)
- Proteasoma(95 prodotti)
- Proteasi serina(55 prodotti)
- p97(15 prodotti)
Mostrare 3 più sottocategorie
Trovati 1095 prodotti di "Proteasi/Proteasoma"
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GM 1489
CAS:GM 1489 is an MMP inhibitor, effective against MMP-1, -2, -3, -8, -9, reduces cancer cell invasion, and prevents ear thickening in mice.Formula:C27H33N3O4Colore e forma:SolidPeso molecolare:463.57GSK2793660 free base
CAS:GSK-2793660, a cathepsin C inhibitor, may treat cystic fibrosis and related lung conditions.Formula:C22H31N3O3Colore e forma:SolidPeso molecolare:385.5THDP-17
CAS:THDP-17 is a inhibitor of glutaminase. THDP-17 shows a partial uncompetitive inhibition in vitro.Formula:C12H16N2SPurezza:98%Colore e forma:SolidPeso molecolare:220.33Garvagliptin
CAS:Garvagliptin has antidiabetic activity.Formula:C18H23F2N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:399.46Cysteine protease inhibitor-2
CAS:Cysteine protease inhibitor from US20070032499A1; halts DCT116 at 6.5μM, PC3 at 4.4μM.Formula:C13H5N5OPurezza:98%Colore e forma:SolidPeso molecolare:247.21ZD8321
CAS:<p>ZD8321 is an effective inhibitor of human Neutrophil elastase (Ki: 13±1.7 nM).</p>Formula:C18H28F3N3O5Purezza:98%Colore e forma:SolidPeso molecolare:423.43Proteasome-IN-1
CAS:Proteasome-IN-1 is an inhibitor of proteasome.Formula:C42H35N5O3Purezza:98%Colore e forma:SolidPeso molecolare:657.76TAPI-1
CAS:TAPI1 (TAPI) , an ADAM17/TACE inhibitor, inhibits shedding of cytokine receptors.Formula:C26H37N5O5Purezza:≥95%Colore e forma:SolidPeso molecolare:499.6GS-9256
CAS:GS-9256 is a selective inhibitor of the HCV NS3 protease, exhibiting favorable pharmacokinetic properties and antiviral activity [1].Formula:C46H56ClF2N6O8PSPurezza:98%Colore e forma:SolidPeso molecolare:957.46Z-LLF-CHO
CAS:Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) effectively inhibits the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex with a Ki value of 460 nM.Formula:C29H39N3O5Purezza:98%Colore e forma:SolidPeso molecolare:509.64MMP13-IN-4
CAS:MMP13-IN-4 (compound 13) is a potent, selective MMP-13 inhibitor with an IC50 of 14.6 μM, implicated in the pathology of osteoarthritis (OA) [1].Formula:C21H17BrN4O5Purezza:98%Colore e forma:SolidPeso molecolare:485.29ND-322 HCl
CAS:ND-322 HCl (ND 322 Hydrochloride) is a selective inhibitor of MT1-MMP and MMP2 and reduces in vitro melanoma cell growth, migration and invasion.Formula:C15H16ClNO3S2Purezza:99.49%Colore e forma:SolidPeso molecolare:357.88Ref: TM-T28145
1mg160,00€5mg354,00€10mg518,00€25mg822,00€50mg1.103,00€100mg1.491,00€1mL*10mM (DMSO)369,00€(S)-BI-1001
CAS:(S)-BI-1001 is an active S-enantiomer of BI-1001. (S)-BI-1001 has antiviral potency against HIV-1 integrase (IC50: 28 nM, and EC50: 450 nM and a Kd: 4.7 μM).Formula:C19H15BrClNO3Purezza:98%Colore e forma:SolidPeso molecolare:420.68PF-00356231 hydrochloride
CAS:PF-00356231 hydrochloride is an inhibitor of matrix metalloproteinase MMP-12 with IC50 of 1.4 μM.Formula:C25H21ClN2O3SPurezza:98.39%Colore e forma:SolidPeso molecolare:464.96Ref: TM-T12414
1mg71,00€5mg187,00€10mg300,00€25mg490,00€50mg678,00€100mg900,00€500mgPrezzo su richiestaNNGH
CAS:NNGH is a matrix metalloproteinase 3 (MMP-3) inhibitor with anticancer activity that counteracts the inhibitory effects of E2 and DHT on RANKL membrane-binding.Formula:C13H20N2O5SPurezza:98.41%Colore e forma:SolidPeso molecolare:316.37Navuridine
CAS:Navuridine (AZdU) is an oral active inhibitor of HIV reverse transcriptase with a relatively short half-life.Formula:C9H11N5O4Purezza:99.83%Colore e forma:SolidPeso molecolare:253.22Ref: TM-T21474
5mg48,00€10mg71,00€25mg131,00€50mg188,00€100mg298,00€500mg1.216,00€1mL*10mM (DMSO)52,00€ZM223 hydrochloride (2031177-48-5 free base)
ZM223 hydrochloride is an orally active, potent non-covalent inhibitor of NEDD8 activating enzyme (NAE), and with excellent anticancer activity.Formula:C23H18ClF3N4O2S2Purezza:98%Colore e forma:SolidPeso molecolare:538.99Flovagatran
CAS:Flovagatran (TGN 255) is a potent, and selective inhibitor of thrombin and parenteral direct factor II.Flovagatran is used to study venous thromboembolism.Formula:C27H36BN3O7Purezza:99.56%Colore e forma:SolidPeso molecolare:525.4RO-9187
CAS:RO-9187 is an effective HCV virus replication inhibitor(IC50: 171 nM).Formula:C9H12N6O5Purezza:98%Colore e forma:SolidPeso molecolare:284.232-MPPA
CAS:2-MPPA (GPI-5693) is a GCP II inhibitor and NAALADase inhibitor, used in research on neurodegenerative diseases.Formula:C8H14O4SPurezza:99.81%Colore e forma:SolidPeso molecolare:206.26Ref: TM-T22497
1mg49,00€5mg104,00€10mg169,00€25mg378,00€50mg655,00€100mg1.169,00€200mg1.586,00€1mL*10mM (DMSO)115,00€Cofrogliptin
CAS:Cofrogliptin (HSK7653) is a DPP-4 inhibitor with hypoglycemic effects, which can be used to study type 2 diabetes (T2D).Formula:C18H19F5N4O3SColore e forma:SolidPeso molecolare:466.43Gosogliptin
CAS:Gosogliptin is a potent, orally active, highly selective, reversible and competitive inhibitor of DPP-4, increasing the level of intestinal GLP-1 and GIP.Formula:C17H24F2N6OPurezza:99.74%Colore e forma:SolidPeso molecolare:366.41Efegatran sulfate
CAS:Efegatran sulfate (LY294468 sulfate) is a potent thrombin inhibitor used in the treatment of thrombotic disorders.Formula:C21H34N6O7SPurezza:≥98% - ≥98%Colore e forma:SolidPeso molecolare:514.6ZD-0892
CAS:<p>ZD-0892: potent, selective neutrophil elastase inhibitor; Ki 6.7 nM (human), 200 nM (porcine).</p>Formula:C24H32F3N3O5Purezza:95% - 99.53%Colore e forma:SolidPeso molecolare:499.52Calpain Inhibitor XII
CAS:<p>Calpain Inhibitor XII (Z-L-Nva-CONH-CH2-2-Py) is a calpain I inhibitor that inhibits calpain II and cathepsin B.</p>Formula:C26H34N4O5Colore e forma:SolidPeso molecolare:482.57MMP2-IN-2
CAS:MMP2-IN-2 is an MMP-2 inhibitor that inhibits MMP-13, MMP-9, and MMP-8, and can be used in the study of cancer and immune diseases.Formula:C13H8N4O4Purezza:98.09%Colore e forma:SolidPeso molecolare:284.23TS-021
CAS:TS-021 is a selective dipeptidyl peptidase 4 (DPP-4) inhibitor with antidiabetic activity for the study of type 2 diabetes.Formula:C17H24FN3O5SPurezza:>99.99% - >99.99%Colore e forma:SolidPeso molecolare:401.45Cathepsin X-IN-1
CAS:<p>Cathepsin X-IN-1 (compound 25) reduces the migration of PC-3 cell with low cytotoxic that is a potent inhibitor of Cathepsin X (IC 50 = 7.13 μM) [1].</p>Formula:C15H13N3O3SPurezza:99.34%Colore e forma:SolidPeso molecolare:315.35CPA inhibitor
CAS:CPA inhibitor (Carboxypeptidase inhibitor) is a potent carboxypeptidase A (CPA) inhibitor with a Ki of 0.32 μM.Formula:C18H19NO4Purezza:99.94%Colore e forma:SolidPeso molecolare:313.35Ref: TM-T10876
1mg57,00€5mg125,00€10mg163,00€25mg278,00€50mg405,00€100mgPrezzo su richiesta1mL*10mM (DMSO)138,00€TY-51469
CAS:TY-51469 is an inhibitor of chymase (IC50s for simian and human chymases: 0.4 and 7.0 nM, respectively).Formula:C20H15FN2O6S4Purezza:99.65%Colore e forma:SolidPeso molecolare:526.6P32/98 hemifumarate
CAS:P32/98 hemifumarate is a DPP4 inhibitor with hypoglycemic properties and is used in the study of type 2 diabetes.Formula:C22H40N4O6S2Purezza:99.46%Colore e forma:SolidPeso molecolare:520.71Isatoribine
CAS:Isatoribine(ANA245) free base is a potent TLR7 receptor agonist with anti-hepatitis C virus infection activity for the study of HCV infection.Formula:C10H12N4O6SPurezza:98.99% - 99.75%Colore e forma:SolidPeso molecolare:316.29Uprifosbuvir
CAS:Uprifosbuvir is an inhibitor of uridine nucleotide analog HCV NS5B polymerase.Formula:C22H29ClN3O9PPurezza:99.73% - >99.99%Colore e forma:SolidPeso molecolare:545.91TG2-IN-3h
CAS:TG2-IN-3h is a highly selective, potent, cell-permeable fluorescent irreversible tissue transglutaminase (tg2) inhibitorFormula:C21H26N4O4SPurezza:99.34% - 99.76%Colore e forma:SolidPeso molecolare:430.52TG-2-IN-1
CAS:TG-2-IN-1 (Compound D003) is a transglutaminase-2 ( TGM-2 ) inhibitor. TG-2-IN-1 can be used in myopia research[1].Formula:C8H13ClN2OSPurezza:98.43%Colore e forma:SolidPeso molecolare:220.72GSK-364735
CAS:GSK-364735 is an HIV-1 IN inhibitor.Formula:C19H18FN3O4Purezza:97.73%Colore e forma:SolidPeso molecolare:371.36(2RS)-FPMPA
CAS:(2RS)-FPMPA（FPMPA） has antiviral activity with an IC50 value of 1.85 μM measured in human MT12 cells infected with SHIV (DH4R).Formula:C9H13FN5O4PPurezza:99.9% - >99.99%Colore e forma:SolidPeso molecolare:305.2CZL55
CAS:CZL55 is a potent caspase-1 inhibitor with an IC50 value of 0.024 μM.CZL55 has low cytotoxicity and can be used in the study of febrile seizures (FS).Formula:C20H22N2O6Purezza:98.19%Colore e forma:SolidPeso molecolare:386.4Lenacapavir
CAS:Lenacapavir (GS-6207) is the first HIV-1 capsid inhibitor approved by the U.S. Food and Drug Administration, the European Medicines Agency, and Health Canada for the treatment of MDR HIV-1 infection.Cost-effective and quality-assured.Formula:C39H32ClF10N7O5S2Purezza:99.61% - 99.87%Colore e forma:SolidPeso molecolare:968.28Ref: TM-T11465
1mg187,00€5mg376,00€10mg565,00€25mg998,00€50mg1.388,00€100mg1.882,00€200mg2.622,00€1mL*10mM (DMSO)615,00€Atevirdine
CAS:<p>Atevirdine is an HIV-1 reverse transcriptase inhibitor with antiviral activity for the study of the AIDS dementia complex (ADC).</p>Formula:C21H25N5O2Purezza:98.20%Colore e forma:SolidPeso molecolare:379.46VRK-IN-1
CAS:VRK-IN-1 is a potent and selective inhibitor of cowpox-associated kinase 1 (VRK1), which can be used in the study of neurological disorders.Formula:C18H11F4NO2Purezza:99.18% - 99.25%Colore e forma:SolidPeso molecolare:349.28Ref: TM-T35863
1mg103,00€5mg236,00€10mg379,00€25mg750,00€50mg1.130,00€100mg1.510,00€200mg2.062,00€1mL*10mM (DMSO)259,00€BMS-929075
CAS:BMS-929075 is an orally active HCV NS5B replicase (HCV NS5B replicase) palm site variant inhibitor with potency, high oral bioavailability and pharmacokineticFormula:C31H24F2N4O3Purezza:99.81% - 99.94%Colore e forma:SolidPeso molecolare:538.54Ref: TM-T26863
1mg180,00€5mg457,00€10mg652,00€25mg1.026,00€50mg1.406,00€100mg1.890,00€500mg3.725,00€1mL*10mM (DMSO)568,00€CP-544439
CAS:CP-544439 is an inhibitor of matrix metalloproteinase-13, which has an effect on adipose tissue development.Formula:C18H19FN2O6SPurezza:95.02% - 98.66%Colore e forma:SolidPeso molecolare:410.4220S Proteasome activator 1
CAS:20S Proteasome activator 1: IC50—0.3 μM (trypsin), 0.7 μM (chymotrypsin), 1.8 μM (caspase); reduces alpha-synuclein A53T, aids neurodegenerative studies.Formula:C27H19ClF2N2OSPurezza:99.82%Colore e forma:SolidPeso molecolare:492.97L 756423
CAS:L756423 is a potent, selective HIV protease inhibitor (Ki=0.049 nM), effective against HIV spread in MT25 lymphocytes at 0.1-0.5 nM, useful for AIDS research.Formula:C39H48N4O5Purezza:99.34% - 99.88%Colore e forma:SolidPeso molecolare:652.82DB04760
CAS:DB04760: selective MMP-13 inhibitor, non-zinc-chelating, IC50=8nM, reduces paclitaxel neurotoxicity, anticancer.Formula:C22H20F2N4O2Purezza:99.93% - 99.99%Colore e forma:SolidPeso molecolare:410.42Ref: TM-T15055
1mg88,00€5mg216,00€10mg325,00€25mg550,00€50mg787,00€100mg1.093,00€500mg2.167,00€1mL*10mM (DMSO)188,00€Sirpiglenastat
CAS:Sirpiglenastat (DRP-104) is a glutamine antagonist, a prodrug of DON, with antitumor activity that acts by suppressing the adaptive immune system.Formula:C22H27N5O5Purezza:98.01% - 98.37%Colore e forma:SolidPeso molecolare:441.48MMP2-IN-3
CAS:MMP2-IN-3 is a potent inhibitor of matrix metalloproteinases (MMP-2) (IC50: 31 μM).Formula:C23H21N3OPurezza:99.38%Colore e forma:SolidPeso molecolare:355.43Ref: TM-T61271
1mg67,00€5mg139,00€10mg205,00€25mg334,00€50mg462,00€100mg622,00€200mg837,00€1mL*10mM (DMSO)148,00€JNJ-10311795
CAS:JNJ-10311795 (RWJ-355871) is an inhibitor of neutrophil elastase G and mast cell chymase, demonstrating significant anti-inflammatory effects.Formula:C40H35N2O6PPurezza:97.43%Colore e forma:SolidPeso molecolare:670.69Opaviraline
CAS:<p>Opaviraline (GW-420867X) is a potent reverse transcriptase inhibitor that inhibits Human immunodeficiency virus 1 and has the potential to treat HIV infection.</p>Formula:C14H17FN2O3Purezza:99.94%Colore e forma:SolidPeso molecolare:280.29Melagatran
CAS:<p>Melagatran is an orally available, direct synthetic thrombin inhibitor that does not require endogenous cofactors other than thrombin.Cost-effective and quality-assured.</p>Formula:C22H31N5O4Purezza:98.29% - >99.99%Colore e forma:SolidPeso molecolare:429.51PG-116800
CAS:PG-116800 (PG-530742) is a matrix metalloproteinase (MMP) inhibitor. PG-116800 can be used in studies about the treatment of osteoarthritis.Formula:C24H27N3O7SPurezza:98.03% - 99.66%Colore e forma:SolidPeso molecolare:501.55BDCRB
BDCRB disrupts HCMV DNA maturation by altering terminase cleavage, extending packaging 30 kb until second site.Formula:C12H11BrCl2N2O4Purezza:99.41% - 99.85%Colore e forma:SoildPeso molecolare:398.04Sovaprevir
CAS:Sovaprevir is a non-structural 3 (NS3) protease inhibitor with antiviral activity for the treatment of HCV infection.Formula:C43H53N5O8SPurezza:99.89%Colore e forma:SolidPeso molecolare:799.97Ref: TM-T28830
1mg266,00€5mg655,00€10mg934,00€25mg1.388,00€50mg1.872,00€100mg2.517,00€1mL*10mM (DMSO)1.035,00€Setrobuvir
CAS:Setrobuvir (ANA-598) is an orally active non-nucleoside HCV NS5B polymerase inhibitor with inhibitory effects on de novo RNA synthesis and primer extension withFormula:C25H25FN4O6S2Purezza:99.95% - 99.97%Colore e forma:SolidPeso molecolare:560.62Ref: TM-T28762
1mg229,00€5mg570,00€10mg812,00€25mg1.216,00€50mg1.663,00€100mg2.242,00€500mg4.494,00€1mL*10mM (DMSO)737,00€BMS-488043
CAS:BMS-488043 is a novel and unique oral small molecule HIV fusion inhibitor that inhibits the attachment of Human Immunodeficiency Virus type 1 (HIV-1) to CD4(+)Formula:C22H22N4O5Purezza:99.95%Colore e forma:SolidPeso molecolare:422.43UPGL00004
CAS:UPGL00004: potent GAC inhibitor, IC50=29 nM, Kd=27 nM, suppresses triple-negative breast cancer cell growth.Formula:C25H26N8O2S2Purezza:97.93%Colore e forma:SolidPeso molecolare:534.66BAY-43-9695
CAS:BAY-43-9695 is a non-nucleoside compound with anti-human cytomegalovirus (HCMV) activity. It is the major metabolite of BAY-38-4766.Formula:C22H25N3O4SPurezza:99.50% - 99.98%Colore e forma:SolidPeso molecolare:427.52MK-8325
CAS:MK-8325 is a potent and orally available HCV NS5A inhibitor with replicative activity against a wide range of genotypes.MK-8325 has demonstrated bioavailabilityFormula:C43H54Cl2F2N8O6SiPurezza:99.61%Colore e forma:SolidPeso molecolare:915.93BILB-1941
CAS:BILB-1941 (BILB-1941ZW) is an inhibitor of HCV NS5B polymerase and can be used in studies about HCV infection.Formula:C34H34N4O4Purezza:99.51% - 99.65%Colore e forma:SolidPeso molecolare:562.66Ref: TM-T26815
1mg313,00€5mg758,00€10mg1.035,00€25mg1.568,00€50mg2.118,00€100mg2.783,00€1mL*10mM (DMSO)1.103,00€NP-313
CAS:NP-313 (NSC-4264) is a potent antithrombotic that blocks platelet aggregation via thromboxane A2 synthesis inhibition and targets SOCC-mediated Ca2+ efflux.Formula:C12H8ClNO3Purezza:99.92%Colore e forma:SolidPeso molecolare:249.652'-C-Methyladenosine
CAS:<p>2'-C-Methyladenosine from C. renalis inhibits HCV, NS5B RNA synthesis (IC50: 0.3, 1.9µM), and LRV1 in L. guyanensis, L. braziliensis.</p>Formula:C11H15N5O4Purezza:99.85%Colore e forma:SolidPeso molecolare:281.27KM-023
CAS:KM-023 is a new second-generation non-nucleoside reverse transcriptase inhibitor for the study of human immunodeficiency virus (HIV) type 1 infection.Formula:C18H19N3O3Purezza:99.03% - 99.47%Colore e forma:SolidPeso molecolare:325.36Ref: TM-T67804
1mg150,00€5mg361,00€10mg542,00€25mg870,00€50mg1.188,00€100mg1.596,00€500mg3.202,00€1mL*10mM (DMSO)359,00€MMP-2/MMP-9 Inhibitor I
CAS:<p>MMP-2/MMP-9-IN-1: oral IV collagenase inhibitor; IC50: 0.24 μM (MMP-9), 0.31 μM (MMP-2); targets cancer.</p>Formula:C21H19NO4SPurezza:99.74%Colore e forma:SolidPeso molecolare:381.44Tyrosinase-IN-2
CAS:Tyrosinase-IN-2, a potent tyrosinase inhibitor, may help in skin lightening and food preservation research.Formula:C8H8N4O2SPurezza:99.78%Colore e forma:SolidPeso molecolare:224.24Ref: TM-T60278
5mg48,00€10mg71,00€25mg135,00€50mg212,00€100mg340,00€200mg467,00€1mL*10mM (DMSO)49,00€Gemigliptin
CAS:Gemigliptin (LC15-0444) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.)Formula:C18H19F8N5O2Purezza:99.72%Colore e forma:SolidPeso molecolare:489.36Ref: TM-T7369
2mg40,00€5mg60,00€10mg87,00€25mg157,00€50mg259,00€100mg406,00€500mg920,00€1mL*10mM (DMSO)88,00€Etarotene
CAS:Etarotene (Arotinoid ethyl sulphone) is an ethylsulfonyl derivative of aloe acid with differentiation-inducing and potentially antitumor activity.Etarotene is aFormula:C25H32O2SPurezza:99.58% - 99.98%Colore e forma:SolidPeso molecolare:396.59HIV-1 integrase inhibitor 8
CAS:<p>HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1].</p>Formula:C21H24O2Purezza:98.91%Colore e forma:SolidPeso molecolare:308.41AGPS-IN-2i
CAS:AGPS-IN-2i inhibits alkylglycerol phosphate synthase, affecting ether lipid metabolism and reducing cancer cell migration and proliferation.Formula:C18H17F2N3O2Purezza:98.92%Colore e forma:SolidPeso molecolare:345.34Ref: TM-T69685
1mg74,00€5mg188,00€10mg311,00€25mg525,00€50mg747,00€100mg1.017,00€1mL*10mM (DMSO)154,00€UK-396082
CAS:UK-396082 is a TAFI inhibitor that inhibits Carboxypeptidase B and can be used in the study of thrombosis, atherosclerosis, cancer and fibrotic conditions.Formula:C12H21N3O2Purezza:99.89%Colore e forma:SolidPeso molecolare:239.31Emivirine
CAS:Emivirine (MKC-442) is a potent and selective nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1.Formula:C17H22N2O3Purezza:99.8%Colore e forma:SolidPeso molecolare:302.37Z-DEVD-CMK
CAS:Z-DEVD-CMK irreversibly inhibits various cathepsins in vitro [1].Formula:C27H35ClN4O12Colore e forma:SolidPeso molecolare:643.04AZD-9819
CAS:AZD-9819 is a neutrophil elastase (HNE) inhibitor applicable for research into chronic obstructive pulmonary disease (COPD).Formula:C25H19F3N6O2Purezza:100% - 99.18%Colore e forma:SolidPeso molecolare:492.45H-Gly-Pro-Hyp-OH acetate
CAS:H-Gly-Pro-Hyp-OH, a peptide dipeptidyl peptidase 4 (DPP-4) inhibitor with an inhibition concentration (IC50) of 2.51 mM, effectively hinders the activity of the DPP-4 enzyme.Formula:C12H19N3O5C2H4O2Colore e forma:SolidPeso molecolare:345.35(Rac)-Neurodegenerative Disorder-Targeting Compound 1
CAS:(Rac)-Neurodegenerative Disorder-Targeting Compound 1 is a calpain inhibitor.Formula:C28H28N4O4Colore e forma:SolidPeso molecolare:484.55Ro 31-9790
CAS:Ro 31-9790 is a synthetic inhibitor of metalloproteinase (MMP).Formula:C15H29N3O4Purezza:98%Colore e forma:SolidPeso molecolare:315.41Thrombin inhibitor 1
CAS:<p>Thrombin inhibitor 1 is a potent inhibitor of thrombin (Ki: 0.66 nM, 2xaPTT=0.43 μM).</p>Formula:C22H20Cl2F2N4O3Purezza:98%Colore e forma:SolidPeso molecolare:497.32AA74-1
CAS:AA74-1 is a potent, selective APEH inhibitor that significantly enhances T-cell proliferation by inhibiting APEH activity [1].Formula:C16H28N4O2Purezza:98%Colore e forma:SolidPeso molecolare:308.42JW 480
CAS:JW480 is a potent and selective inhibitor of KIAA1363, a serine hydrolase enzyme.Formula:C22H23NO2Purezza:99.72%Colore e forma:SolidPeso molecolare:333.42Ref: TM-T22883
2mg38,00€5mg51,00€10mg84,00€25mg169,00€50mg273,00€100mg439,00€200mg620,00€1mL*10mM (DMSO)60,00€Flovagatran sodium
CAS:Flovagatran sodium, a thrombin inhibitor, is used potentially for the treatment of thrombosis.Formula:C27H36BN3NaO7Purezza:98%Colore e forma:SolidPeso molecolare:548.4BAY-320
CAS:BAY-320 is a Bub1 inhibitor. With an IC50 of 680 nM for human Bub1 in the presence of 2 mM ATP.Formula:C26H26F2N6O2Purezza:98%Colore e forma:SolidPeso molecolare:492.52SQ 32056
CAS:SQ 32056 is a cathepsin E inhibitor.Formula:C37H56N4O5Purezza:98%Colore e forma:SolidPeso molecolare:636.86BMS-189664 HCl
CAS:BMS-189664 HCl is a selective and orally active thrombin active site inhibitor.Formula:C22H35ClN6O4SPurezza:98%Colore e forma:SolidPeso molecolare:515.07Tyropeptin A-4
CAS:Tyropeptin A-4 is used as a proteasome inhibitor.Formula:C31H41N3O6Purezza:98%Colore e forma:SolidPeso molecolare:551.67LM-030
CAS:LM-030, also known as BPR277, is a novel inhibitor of kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2).Formula:C46H72N8O12Colore e forma:SolidPeso molecolare:929.11M190S
CAS:M109S is a novel small molecule that shields cells from mitochondria-dependent apoptosis, demonstrating effectiveness both in vitro and in vivo.Formula:C21H21N5O2Purezza:98%Colore e forma:SolidPeso molecolare:375.42NS5A-IN-3
CAS:NS5A-IN-3 is a potent NS5A inhibitor with high efficacy against HCV 1b, good activity on 3a, and strong metabolic stability; superior to daclatasvir.Formula:C44H44N6O8Purezza:98%Colore e forma:SolidPeso molecolare:784.86Azt-pmap
CAS:AZT-PMPA, an aryl phosphate derivative of AZT and a nucleoside analogue, demonstrates anti-HIV activity[1].Formula:C20H25N6O8PPurezza:98%Colore e forma:SolidPeso molecolare:508.42HIV-1 protease-IN-11
CAS:HIV-1 protease-IN-11 (compound 34a), an HIV-1 protease inhibitor, demonstrates potent inhibition with an IC50 of 0.41 nM and maintains substantial efficacyFormula:C26H37N3O5SPurezza:98%Colore e forma:SolidPeso molecolare:503.65HIV-1 protease-IN-8
CAS:HIV-1 protease-IN-8 (compound 34b) is a potent inhibitor of the HIV-1 protease enzyme, exhibiting an IC50 of 0.32 nM.Formula:C25H35N3O5SPurezza:98%Colore e forma:SolidPeso molecolare:489.63HIV-1 protease-IN-7
CAS:HIV-1 protease-IN-7 (compound 16) is an orally active inhibitor of HIV-1 protease, exhibiting an IC50 of 3.52 nM and an EC50 of 37 nM [1].Formula:C68H104N10O12SPurezza:98%Colore e forma:SolidPeso molecolare:1285.68HIV-1 protease-IN-12
CAS:HIV-1 protease-IN-12 (compound 35b) serves as a potent inhibitor of HIV-1 protease, exhibiting an IC50 value of 0.51 nM, and demonstrates efficacy against drug-Formula:C25H35N3O5SPurezza:98%Colore e forma:SolidPeso molecolare:489.63NS5A-IN-2
CAS:NS5A-IN-2, a potent inhibitor, is highly effective against HCV 1b and shows increased activity for GT 3a with good metabolic stability.Formula:C46H45N7O7Purezza:98%Colore e forma:SolidPeso molecolare:807.89NCI-B16
CAS:NCI-B16 is a small-molecule RNA binder that inhibits HCV (hepatitis C virus) replication [1].Formula:C27H26N8O4Colore e forma:SolidPeso molecolare:526.55HIV-1 protease-IN-9
CAS:HIV-1 protease-IN-9 (compound 5b), a potent HIV-1 protease inhibitor, exhibits strong antiviral efficacy with a dissociation constant (K_i) of 0.028 nM and aFormula:C37H41N7O4SPurezza:98%Colore e forma:SolidPeso molecolare:679.83TP0556351
CAS:TP0556351: potent MMP2 inhibitor with 0.2 nM IC50, reduces collagen in pulmonary fibrosis mice.Formula:C50H70N10O16Purezza:98%Colore e forma:SolidPeso molecolare:1067.15HCV-IN-44
CAS:HCV-IN-44 (compound 28) is an inhibitor of the HCV NS5B protein, efficacious in suppressing HCV virus replication and useful for researching HCV infection [1].Formula:C24H26FN3O5SColore e forma:SolidPeso molecolare:487.54(1R,4S)-Yimitasvir diphosphate
CAS:Yimitasvir diphosphate, also known as Emitasvir, is an orally-administered inhibitor of the hepatitis C virus (HCV) nonstructural protein 5A (NS5A).Formula:C49H64N8O14P2Colore e forma:SolidPeso molecolare:1051.03MeOSuc-AAPV-CMK
CAS:MeOSuc-AAPV-CMK (Elastase Inhibitor III) serves as an inhibitor of elastase, as well as cathepsin G and proteinase 3, and impedes leukocyte elastase-mediatedFormula:C22H35ClN4O7Colore e forma:SolidPeso molecolare:502.99Ecallantide
CAS:Ecallantide (DX-88) is a recombinant inhibitor specifically targeting plasma kallikrein, which serves to impede the synthesis of bradykinin.Formula:C305H448N88O91S8Colore e forma:SolidPeso molecolare:7059.88DCLK1-IN-2
CAS:DCLK1-IN-2 (Compound I-5) is a potent inhibitor of DCLK1, exhibiting an IC50 of 171.3 nM, and demonstrates significant antiproliferative effects on SW1990 cellFormula:C26H32N8O3SColore e forma:SolidPeso molecolare:536.65AZD-7295
CAS:AZD-7295 (A-689) is an NS5A inhibitor that may be used to treat HCV infection.Formula:C32H35F3N4O5SColore e forma:SolidPeso molecolare:644.7ND-378
CAS:ND-378 is a potent and selective inhibitor of MMP-2 with no inhibition on MMP-9 and MMP-14.Formula:C18H19NO4S2Purezza:98%Colore e forma:SolidPeso molecolare:377.48ONO 4817
CAS:ONO-4817 suppresses MMPs, limiting plaque progression and aortic hyperplasia in hyperlipidemic rabbits.Formula:C22H28N2O6Colore e forma:SolidPeso molecolare:416.47GS-6620
CAS:GS-6620 is a HCV nonstructural protein 5B (NS5B) inhibitor.Formula:C29H37N6O9PColore e forma:SolidPeso molecolare:644.61Ro 32-7315
CAS:Ro 32-7315 is a selective inhibitor of ADAM17.Formula:C22H35N3O5SPurezza:98%Colore e forma:SolidPeso molecolare:453.6Berotralstat HCl
CAS:Berotralstat HCl is a selective plasma kallikrein inhibitor, reducing pain and swelling in HAE by blocking bradykinin release.Formula:C30H28Cl2F4N6OColore e forma:SolidPeso molecolare:635.4886Kallikrein-IN-2
CAS:Kallikrein-IN-2 (compound 1) is an inhibitor of the kinin-releasing enzyme Kallikrein.Formula:C28H25F3N4O4Colore e forma:SolidPeso molecolare:538.52Proteasome-IN-4
Proteasome-IN-4, a potent non-covalent inhibitor (IC50=8.39nM), halts cancer cell growth, useful for oncology studies.Formula:C44H58N6O5Colore e forma:SolidPeso molecolare:750.97Cathepsin Inhibitor 2
CAS:Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor (Ki: <20 nM).Formula:C19H21F6N3OPurezza:98%Colore e forma:SolidPeso molecolare:421.38PNU-103017
CAS:PNU-103017 is an inhibitor of HIV protease.Formula:C28H28N2O5SPurezza:98%Colore e forma:SolidPeso molecolare:504.6Cathepsin K inhibitor 3
CAS:Cathepsin K inhibitor 3: Selective, IC50 of 0.5 nM, good pharmacokinetics, potential for OA research.Formula:C30H31FN4O4SColore e forma:SolidPeso molecolare:562.65MMP-9 Inhibitor I
CAS:MMP-9 inhibitor I is an inhibitor of matrix metalloproteinase-9 (MMP-9) that is selective over MMP-1 and MMP-13 (IC50s = 5, 1,050, and 113 nM, respectively).Formula:C27H33N3O5SColore e forma:SolidPeso molecolare:511.63Ravidasvir HCl
CAS:Ravidasvir, also known as PPI-668 and ASC16, is a second-generation, orally active, potent and selective HCV NS5A protein inhibitor.Formula:C42H52Cl2N8O6Colore e forma:SolidPeso molecolare:835.828MMP-7-IN-2
CAS:MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.Formula:C28H40ClF3N6O9SPurezza:97.82%Colore e forma:SolidPeso molecolare:729.17Atecegatran metoxil
CAS:Atecegatran Metoxil (AZD0837), an oral thrombin inhibitor in development for stroke prevention in atrial fibrillation, is well-tolerated with favorable PK.Formula:C22H23ClF2N4O5Colore e forma:SolidPeso molecolare:496.89Cyclotheonellazole A
CAS:Cyclotheonellazole A inhibits elastase (IC50=0.034nM) & chymotrypsin (IC50=0.62nM), a natural macrocyclic peptide.Formula:C44H54N9NaO14S2Colore e forma:SolidPeso molecolare:1020.07Inogatran
CAS:Inogatran is a synthetic thrombin inhibitor, developed for the possible treatment and prophylaxis of venous and arterial thrombotic diseases.Formula:C21H38N6O4Purezza:98%Colore e forma:SolidPeso molecolare:438.56I-XW-053
CAS:I-XW-053 is an inhibitor of capsid targeted HIV-1 replication using the hybrid structure based method to block the interface between CA N-terminal domains (NTD-Formula:C22H16N2O2Purezza:99.05%Colore e forma:SolidPeso molecolare:340.37LY52
CAS:LY52 is a matrix metalloproteinase-2 inhibitor. It acts by suppressing tumor invasion and metastasis.Formula:C22H24N4O6Purezza:98%Colore e forma:SolidPeso molecolare:440.45KCC009
CAS:KCC009 is a potent and selective Transglutaminase 2 Inhibitor.Formula:C21H22BrN3O5Colore e forma:SolidPeso molecolare:476.32JTK-853
CAS:JTK-853: novel non-nucleoside HCV polymerase inhibitor with strong antiviral activity (EC50: 0.38 μM genotype 1a, 0.035 μM 1b).Formula:C28H23F7N6O4S2Purezza:98%Colore e forma:SolidPeso molecolare:704.64PTC725
CAS:PTC725 is a selective HCV 1b replicons inhibitor. It has been shown to target the nonstructural protein 4B.Formula:C23H18F4N6O2SPurezza:98%Colore e forma:SolidPeso molecolare:518.49MK-3281
CAS:MK-3281: Oral, potent HCV NS5B inhibitor with promising properties and efficacy in replication trials, suitable for clinical use.Formula:C29H37N3O3Colore e forma:SolidPeso molecolare:475.62Cipemastat
CAS:Cipemastat is a competitive inhibitor of human collagenases 1, 2, and 3 (Kis: 3.0, 4.4, and 3.4 nM).Formula:C22H36N4O5Purezza:98%Colore e forma:SolidPeso molecolare:436.55Petesicatib
CAS:Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases.Formula:C25H23F6N5O4SPurezza:99.76%Colore e forma:SolidPeso molecolare:603.54Ref: TM-T16474
1mg105,00€5mg250,00€10mg393,00€25mg777,00€50mg1.198,00€100mg1.549,00€200mg2.080,00€1mL*10mM (DMSO)331,00€MMP13-IN-3
CAS:MMP13-IN-3 is an oral, selective MMP-13 inhibitor with IC50 of 1 nM, >1000x selective, for osteoarthritis treatment.Formula:C24H22N4O5Purezza:99.76%Colore e forma:SolidPeso molecolare:446.46Ref: TM-T16124
1mg87,00€5mg216,00€10mg354,00€25mg620,00€50mg847,00€100mg1.169,00€1mL*10mM (DMSO)240,00€FK706
CAS:FK706, a human neutrophil elastase inhibitor (IC50: 83 nM, Ki: 4.2 nM), also blocks mouse and porcine elastases. Anti-inflammatory.Formula:C26H33F3N4NaO7Colore e forma:SolidPeso molecolare:593.556XL-784
CAS:XL-784 is a selective MMP inhibitor with low IC50s for MMP-1,2,3,8,9,13, modulating extracellular matrix remodeling, tumor invasion, and metastasis in cancer.Formula:C42H42Cl2F4MgN6O16S2Purezza:98%Colore e forma:SolidPeso molecolare:1122.15Collagen proline hydroxylase inhibitor
CAS:<p>Collagen proline hydroxylase inhibitor is an inhibitor collagen proline hydroxylase and useful for antifibrotic proliferative agents.</p>Formula:C18H18N4O4Purezza:98%Colore e forma:SolidPeso molecolare:354.36NK3201
CAS:NK3201, a specific chymase inhibitor, suppresses bleomycin-induced pulmonary fibrosis in hamsters.Formula:C31H29N5O6Purezza:98%Colore e forma:SolidPeso molecolare:567.59Z-PDLDA-NHOH
CAS:Z-PDLDA-NHOH is a potent, specific vertebrate collagenase inhibitor [1].Formula:C22H32N4O6Colore e forma:SolidPeso molecolare:448.51GSK-2485852
CAS:GSK-2485852, a NS5B inhibitor, is used potentially for treatment of HCV infection.Formula:C27H25BF2N2O6SColore e forma:SolidPeso molecolare:554.37Reverse transcriptase-IN-1
CAS:Reverse transcriptase-IN-1 is a diarylbenzopyrimidine (DABP) analogue and a potent inhibitor of HIV-1 nonnucleoside reverse transcriptase with an IC50of 13.7Formula:C25H17N7O2Purezza:99.61%Colore e forma:SolidPeso molecolare:447.45Ref: TM-T12715
1mg64,00€5mg131,00€10mg183,00€25mg311,00€50mg449,00€100mg615,00€200mg833,00€1mL*10mM (DMSO)143,00€XL-784 free base
CAS:XL-784 free base selectively inhibits MMPs with IC50: MMP-1 (1.9µM), MMP-2 (0.81nM), MMP-3 (120nM), MMP-8 (10.8nM), MMP-9 (18nM), MMP-13 (0.56nM).Formula:C21H22ClF2N3O8SPurezza:98%Colore e forma:SolidPeso molecolare:549.93MDL-101146, (R)-
CAS:MDL-101146, (R)- is an effective orally active inhibitor of human neutrophil elastase.Formula:C29H37F5N4O6Purezza:98%Colore e forma:SolidPeso molecolare:632.62DS-1040 Tosylate
CAS:DS-1040 Tosylate is a thrombin-activated fibrinolysis inhibitor (TAFI) inhibitor and a fibrinolysis enhancer, used for researching thromboembolic diseases.Formula:C23H35N3O5SColore e forma:SolidPeso molecolare:465.61SSR 69071
CAS:SSR69071: selective neutrophil elastase inhibitor, stronger for humans (Ki=0.0168 nM), may treat COPD, asthma, and reduce heart injury.Formula:C27H32N4O7SColore e forma:SolidPeso molecolare:556.63Phe-Pro-Ala-pNA
CAS:Phe-Pro-Ala-pNA is a chromogenic substrate utilized for assessing tripeptidyl peptidase activity.Formula:C23H27N5O5Colore e forma:SolidPeso molecolare:453.49MDL 27324
CAS:MDL 27324 is an inhibitor of human neutrophil elastase.Formula:C29H38F3N5O6SPurezza:98%Colore e forma:SolidPeso molecolare:641.7BAY-678
CAS:BAY-678: Oral selective human neutrophil elastase inhibitor; IC50: 20 nM; SGC-approved chemical probe.Formula:C20H15F3N4O2Purezza:99.36%Colore e forma:SolidPeso molecolare:400.35Ref: TM-T10473
5mg39,00€10mg64,00€25mg126,00€50mg183,00€100mg279,00€200mg395,00€1mL*10mM (DMSO)44,00€Z-FG-NHO-BzOME
CAS:Z-FG-NHO-BzOME is a chemical compound functioning as a cysteine protease inhibitor, selectively targeting and inhibiting cathepsin B, cathepsin L, cathepsin S,Formula:C27H27N3O7Colore e forma:SolidPeso molecolare:505.52KB-R7785
CAS:KB-R7785 is a novel ADAM12/MMP inhibitor improving heart function and insulin sensitivity by blocking HB-EGF and TNF-alpha.Formula:C18H27N3O4Colore e forma:SolidPeso molecolare:349.42MDL 101146
CAS:MDL 101146 is an orally active neutrophil elastase inhibitor.Formula:C29H37F5N4O6Purezza:98%Colore e forma:SolidPeso molecolare:632.62O-Benzoylhydroxylamine
CAS:O-Benzoyl hydroxylamine exhibits properties as a dipeptidyl peptidase-IV (DPP-IV) inhibitor and demonstrates antidiabetic effects[1].Formula:C7H7NO2Colore e forma:SolidPeso molecolare:137.14Neurodegenerative Disorder-Targeting Compound 1
CAS:Neurodegenerative Disorder-Targeting Compound 1 is an inhibitor of calpain [1].Formula:C28H28N4O4Purezza:98%Colore e forma:SolidPeso molecolare:484.55MMP-7-IN-3
CAS:MMP-7-IN-3 (compound 15) is a potent and selective MMP-7 inhibitor, inhibiting renal fibrosis in a unilateral ureteral obstruction mouse model.Formula:C34H43ClF3N7O9SPurezza:99.915%Colore e forma:SolidPeso molecolare:818.26MMP-145
CAS:MMP-145 is used as a protease inhibitor.Formula:C20H20N2O7SPurezza:98%Colore e forma:SolidPeso molecolare:432.45BMS-189664
CAS:BMS-189664 is an inhibitor of thrombin.Formula:C22H34N6O4SPurezza:98%Colore e forma:SolidPeso molecolare:478.61MMP-3 Inhibitor VIII
CAS:Matrix metalloproteinase-3 (MMP-3), also known as stromelysin-1, is a critical enzyme involved in tissue remodeling and repair through its role in degrading extracellular matrix proteins, facilitating cell migration. This enzyme has been implicated in various physiological processes including vascular remodeling associated with aneurysm formation, wound healing, the progression of atherosclerosis, and tumor initiation. MMP-3 inhibitor VIII, a cell-permeable sulfonamide-based hydroxamic acid, effectively inhibits MMP-3 by binding to its active site (Ki = 23 nM), thus blocking its enzymatic activity. Additionally, this inhibitor has been demonstrated to suppress the activity of mouse macrophage metalloelastase MME/MMP-12, with an IC50 value of 13 nM, highlighting its potential utility in research on tissue remodeling and disease processes involving MMPs.Formula:C20H26N2O5SColore e forma:SolidPeso molecolare:406.5GSK-625433
CAS:GSK-625433: Homochiral inhibitor blocks HCV genotypes 1a/1b polymerase.Formula:C26H32N4O5SColore e forma:SolidPeso molecolare:512.62Dim16
CAS:Dim16, a dual inhibitor of PCSK9/HMG-CoAR, demonstrates potent activity with an IC50 of 19 nM against PCSK9 and significantly impedes PCSK9-LDLR interactionFormula:C29H38IN5Colore e forma:SolidPeso molecolare:583.55HCV-IN-43
CAS:HCV-IN-43 (compound 2), an HCV NS5B protein inhibitor, efficiently inhibits HCV virus replication and is utilized in the study of HCV infection [1].Formula:C26H26FN3O5SColore e forma:SolidPeso molecolare:511.57Mergetpa
CAS:Mergetpa, a carboxypeptidase inhibitor, impedes the conversion of kinins and B2 receptor antagonists into metabolites devoid of the C-terminal arginine [1].Formula:C7H15N3O2S2Purezza:98%Colore e forma:SolidPeso molecolare:237.34EP1013
CAS:EP1013 is a broad-spectrum selective inhibitor of Caspase used in the study of type 1 diabetes.Formula:C18H23FN2O6Purezza:98%Colore e forma:SolidPeso molecolare:382.38LU-002i
CAS:LU-002i is a selective inhibitor targeting the human proteasome subunits β2c and β2i, demonstrating an inhibitory concentration (IC50) of 220 nM for β2i [1].Formula:C35H52N4O7Purezza:98%Colore e forma:SolidPeso molecolare:640.81Beclabuvir HCl
CAS:Beclabuvir (BMS-791325) is an HCV inhibitor targeting NS5B polymerase with sub-28 nM potency for genotypes 1, 3, 4, 5.Formula:C36H46ClN5O5SColore e forma:SolidPeso molecolare:696.3Paltimatrectinib
CAS:Paltimatrectinib (PBI-200) is a tyrosine kinase inhibitor with anticancer activity, and is used in the study of bladder, breast, and colorectal cancers.Formula:C20H15F5N6Purezza:99.96%Colore e forma:SolidPeso molecolare:434.37Proteasome-IN-5
CAS:<p>Proteasome-IN-5, also known as compound 5, acts as a proteasome inhibitor [1].</p>Formula:C20H30BN5O7Purezza:98%Colore e forma:SolidPeso molecolare:463.29M867
CAS:M867 is a selective, reversible caspase-3 inhibitor, possessing an IC50 of 1.4 nM and a Ki value of 0.7 nM, demonstrating anti-apoptotic activity [1].Formula:C27H43N7O6Purezza:98%Colore e forma:SolidPeso molecolare:561.67Proteasome β2c/i-IN-1
CAS:Proteasome β2c/i-IN-1 (compound 37) serves as a selective inhibitor targeting the β2c and β2i subunits of the human proteasome [1].Formula:C32H48N4O7Purezza:98%Colore e forma:SolidPeso molecolare:600.75MMP3 inhibitor 1
CAS:MMP3 inhibitor 1 is a potent and highly selective inhibitor of MMP-3 (IC50 of 1 nM).Formula:C23H31N3O6SPurezza:98%Colore e forma:SolidPeso molecolare:477.57L-689502
CAS:L-689502 is a potent HIV-l protease inhibitor (IC50: 1 nM).Formula:C39H51N3O7Purezza:98%Colore e forma:SolidPeso molecolare:673.84MMP-9-IN-8
CAS:MMP-9-IN-8 (Compound 3), an MMP-9 inhibitor, exhibits inhibitory activities of 42.16% at 10 μM and 58.28% at 50 μM.Formula:C20H21F4N7OColore e forma:SolidPeso molecolare:451.42LU-005i
CAS:LU-005i is a powerful inhibitor targeting the β5i subunit of immunoproteasomes, displaying a high potency with an IC 50 value of 6.6 nM, and exhibits selectivity by preferring β5i over the β5c subunit, which has an IC 50 value of 287 nM [1].Formula:C31H46N4O7Colore e forma:SolidPeso molecolare:586.72ASP-8497
CAS:ASP8497 is a potent DPP-IV inhibitor enhancing GLP-1, used for type 2 diabetes and glucose intolerance.Formula:C18H27FN4O7SColore e forma:SolidPeso molecolare:462.49ABP 25
CAS:ABP 25 is a highly potent and selective activity-based probe (ABP) for cathepsin K imaging.Formula:C55H66ClN5O3Colore e forma:SolidPeso molecolare:880.6LONP1-IN-2
CAS:LONP1-IN-2: Potent LONP1 inhibitor, IC50=0.187μM; weak on 20S proteasome (>10μM); for cancer research.Formula:C16H27BN4O4Colore e forma:SolidPeso molecolare:350.22LMP7-IN-2
CAS:LMP7-IN-2 is an inhibitor of LMP7 and may be utilized in the treatment of associated inflammatory diseases and disorders [1].Formula:C28H27N3O3SColore e forma:SolidPeso molecolare:485.6Z-LVG
CAS:Z-LVG, an irreversible cysteine protease inhibitor and a tripeptide derivative of cystatin C, serves as an inhibitor of viral replication and is utilized inFormula:C21H31N3O6Colore e forma:SolidPeso molecolare:421.49Cardanol diene
CAS:Cardanol diene: phenol in cashew shells; anti-tyrosinase (IC50=52.5μM); used to make anti-E. coli biofilm complexes.Formula:C21H32OColore e forma:SolidPeso molecolare:300.48BMS-538305 HCl
CAS:BMS-538305 is a potent, selective inhibitor of dipeptidyl peptidase IV (DPP-IV).Formula:C17H27ClN2O2Colore e forma:SolidPeso molecolare:326.86γ-Glu-Tyr
CAS:<p>gamma-Glu-Tyr (gamma-Glutamyltyrosine) is a kokumi peptide against dipeptidyl peptidase-IV (DPP-IV) and is used in the study of diabetes mellitus.</p>Formula:C14H18N2O6Purezza:98.92%Colore e forma:SolidPeso molecolare:310.3Filibuvir
CAS:<p>Filibuvir (PF-00868554) inhibits HCV polymerase genotypes 1a/1b, EC50s 59 nM.</p>Formula:C29H37N5O3Purezza:99.28% - >99.99%Colore e forma:SolidPeso molecolare:503.64MK-0674
CAS:MK-0674 is a cathepsin K inhibitor (IC50: 0.4 nM) that inhibits Cat B, Cat F, Cat L, and Cat S for metabolism-related diseases.Formula:C26H27F6N3O2Purezza:97.3% - 99.91%Colore e forma:SolidPeso molecolare:527.5ZED-1227
CAS:<p>ZED-1227 (TAK-227) is a TG2 inhibitor with anticancer activity that blocks inflammation-induced TG2 expression and activation for the treatment of Celiac Diseas</p>Formula:C26H36N6O6Purezza:99.04%Colore e forma:SolidPeso molecolare:528.6Nesbuvir
CAS:Nesbuvir: HCV NS5B polymerase inhibitor, IC50 9 nM against HCV 1b replicon in liver cancer cells.Formula:C22H23FN2O5SPurezza:99.99%Colore e forma:SolidPeso molecolare:446.49Ref: TM-TQ0090
1mg64,00€2mg93,00€5mg140,00€10mg183,00€25mg319,00€50mg467,00€100mg610,00€200mg823,00€1mL*10mM (DMSO)156,00€HIV-1 inhibitor-54
CAS:HIV-1 inhibitor-54: potent anti-HIV (EC50: 32 nM), targets WT HIV-1 IIIB in MT-4 cells for infection research.Formula:C27H30N6O4SPurezza:98.05% - 99.39%Colore e forma:SoildPeso molecolare:534.63Ac-YVAD-AOM
CAS:Ac-YVAD-AOM is a selective and potent caspase-1 inhibitor showing antitumor activity and potential analgesic activity.Formula:C33H42N4O10Purezza:98%Colore e forma:SolidPeso molecolare:654.71BMS-212122
CAS:BMS-212122 inhibits MTP, reduces lipids and plaque in animal tests.Formula:C43H36F6N4O2Purezza:99.85%Colore e forma:SolidPeso molecolare:754.76Ref: TM-T30506
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€Collagen proline hydroxylase inhibitor-1
CAS:Collagen proline hydroxylase inhibitor-1 具有抗纤维增生活性。Formula:C24H21N5O4Purezza:99.57%Colore e forma:SolidPeso molecolare:443.45Aderamastat
CAS:Aderamastat (FP-025) is an orally active matrix metalloproteinase 12 (MMP-12) inhibitor indicated for the study of allergic asthma, COPD and pulmonary fibrosis.Formula:C21H18N2O4SPurezza:99.35%Colore e forma:SolidPeso molecolare:394.44VBY-825
CAS:VBY-825 is a reversible inhibitor of cathepsin with high potency against cathepsins B, L, S and V.Formula:C23H29F4N3O5SPurezza:99.91%Colore e forma:SolidPeso molecolare:535.55HCV-IN-7
CAS:HCV-IN-7: potent oral HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.Formula:C40H48N8O6SPurezza:98%Colore e forma:SolidPeso molecolare:768.92UK-370106
CAS:UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-Formula:C35H44N2O5Purezza:98%Colore e forma:SolidPeso molecolare:572.73Idraparinux Na
CAS:Idraparinux Na is an Antithrombotic, Indirect, Selective, Synthetic Factor Xa InhibitorFormula:C38H55Na9O49S7Colore e forma:SolidPeso molecolare:1727.14RXP03
CAS:RXP03 is an MMPs inhibitor with K_i values of 20 nM for MMP-2, 2.5 nM for MMP-8, 10 nM for MMP-9, 5 nM for MMP-11, and 105 nM for MMP-14 [1].Formula:C39H43N4O6PColore e forma:SolidPeso molecolare:694.76GLS-1-IN-1
GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor that inhibits Hep G2, MCF 7 and MCF 10A cells.Formula:C26H25FN4OSColore e forma:SolidPeso molecolare:460.57Verducatib
CAS:<p>Verducatib is an inhibitor of cathepsins (cathepsin).</p>Formula:C31H35FN4O3Colore e forma:SolidPeso molecolare:530.633BMT-052
CAS:BMT-052 is a potent and selective Pan-genotypic HCV NS5B Polymerase Inhibitor (EC50 = 7 nM).Formula:C30H17D9F4N6O5Purezza:98%Colore e forma:SolidPeso molecolare:635.61SSR-182289A (Free)
CAS:SSR-182289A (Free) is a thrombin inhibitor.Formula:C30H33F2N5O4SPurezza:98%Colore e forma:SolidPeso molecolare:597.68Faldaprevir sodium
CAS:Faldaprevir sodium: HCV treatment, inhibits NS3/NS4A protease, P-glycoprotein, CYP3A4, UGT1A1.Formula:C40H48BrN6NaO9SColore e forma:SolidPeso molecolare:891.81Belactin A
CAS:Belactin A acts as an inhibitor of vasohibin-1 [VASH-1] with an IC50 of 0.18 µg/ml.Formula:C17H21ClN2O4Peso molecolare:352.81CE-2072
CAS:CE-2072 is a synthetic host serine proteases inhibitor.Formula:C33H41N5O6Purezza:98%Colore e forma:SolidPeso molecolare:603.71CM-352
CAS:CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage.Formula:C24H29N3O6SPurezza:97.24%Colore e forma:SolidPeso molecolare:487.57BAY-7598
CAS:BAY-7598 is a potent, selective, and orally bioavailable MMP12 inhibitor (IC50s: 0.085, 0.67, and 1.1 nM for human/murine/rat MMP12).Formula:C28H31N3O6Purezza:98%Colore e forma:SolidPeso molecolare:505.56Faldaprevir
CAS:Faldaprevir is an orally effective, selective, non-covalent HCV NS3/4A protease inhibitor with high inhibitory activity against HCV 1a and 1b genotype.Formula:C40H49BrN6O9SPurezza:99.04% - 99.19%Colore e forma:SolidPeso molecolare:869.82GW311616 hydrochloride
CAS:GW-311616 hydrochloride is a long duration, orally bioavailable, and selective human neutrophil elastase (HNE) inhibitor (IC50: 22 nM; Ki: 0.31 nM).Formula:C19H32ClN3O4SPurezza:98%Colore e forma:SolidPeso molecolare:433.99AMG-222 tosylate
CAS:AMG-222 tosylate is a DPP-IV inhibitor in clinical development for type II diabetes.Formula:C39H47N9O6SColore e forma:SolidPeso molecolare:769.91HsClpP activator-1
CAS:HsClpP activator-1 (compound 24) is a potent activator of HsClpP, with an EC50 of 0.22 μM. It effectively inhibits cancer cell growth, exhibiting IC50 values ranging from 0.1 to 1 μM.Formula:C23H20F5N3O2Colore e forma:SolidPeso molecolare:465.42
