Proteasi/Proteasoma
Gli inibitori delle proteasi e del proteasoma sono composti che bloccano l'attività delle proteasi e del proteasoma, che sono coinvolti nella degradazione e nel turnover delle proteine. Questi inibitori sono fondamentali per studiare la regolazione dell'omeostasi proteica, il controllo del ciclo cellulare e l'apoptosi. Gli inibitori delle proteasi e del proteasoma vengono anche utilizzati nel trattamento di malattie come il cancro, dove la degradazione anomala delle proteine svolge un ruolo nella progressione della malattia. Inibendo le proteasi o il proteasoma, questi composti possono indurre la morte cellulare nelle cellule tumorali e sono strumenti critici sia per la ricerca di base che per lo sviluppo terapeutico. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle proteasi e del proteasoma di alta qualità per supportare la tua ricerca in biochimica, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Proteasi/Proteasoma"
- Acetil-CoA carbossilasi(38 prodotti)
- Cisteina proteasi(111 prodotti)
- DPP-4(27 prodotti)
- Glutaminasi(46 prodotti)
- Proteasi HIV(506 prodotti)
- PAI-1(26 prodotti)
- Inibitori della proteasi(50 prodotti)
- Ricettore attivato dalla proteasi(55 prodotti)
- Proteasoma(85 prodotti)
- Proteasi serina(54 prodotti)
- p97(15 prodotti)
Mostrare 3 più sottocategorie
Trovati 984 prodotti di "Proteasi/Proteasoma"
Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
GW280264X
CAS:GW280264X (Carbamic acid) is an inhibitor of ADAM17 .Formula:C28H41N5O6SPurezza:99.51%Colore e forma:SolidPeso molecolare:575.72Ref: TM-T8961
1mg156,00€5mg319,00€10mg477,00€25mg773,00€50mg1.063,00€100mg1.431,00€1mL*10mM (DMSO)404,00€Chlorcyclizine
CAS:CHLORCYCLIZINE is a histamine H1 antagonist and a potent hepatitis C virus (HCV) entry inhibitor.Formula:C18H21ClN2Purezza:98.75%Colore e forma:SolidPeso molecolare:300.83Samatasvir
CAS:Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) is a pan-genotypic inhibitor of the HCV non-structural protein 5A.Formula:C47H48N8O6S2Purezza:98.03%Colore e forma:SolidPeso molecolare:885.06Ref: TM-T9567
1mg55,00€5mg116,00€10mg187,00€25mg376,00€50mg632,00€100mg1.008,00€1mL*10mM (DMSO)197,00€UAMC00039 dihydrochloride
CAS:UAMC00039 dihydrochloride is a potent, reversible and competitive dipeptidyl peptidase II inhibitor with an IC50 of 0.48 nM.Formula:C16H26Cl3N3OPurezza:>99.99%Colore e forma:SolidPeso molecolare:382.76PSI-6206
CAS:PSI-6206 (RO 2433) (RO2433) is a selective HCV RNA polymerase inhibitor.Formula:C10H13FN2O5Purezza:98% - 99.79%Colore e forma:SolidPeso molecolare:260.22NM107
CAS:NM107, a ribonucleoside, inhibits HCV NS5B polymerase. It has broad antiviral properties with EC50 of 1.85 μM in wild-type cells.Formula:C10H15N3O5Purezza:97.85%Colore e forma:White To Off-White PowderPeso molecolare:257.24ML281
CAS:ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM.Formula:C22H19N3O2SPurezza:99.12% - 99.87%Colore e forma:SolidPeso molecolare:389.47Ref: TM-T3423
1mg34,00€5mg75,00€10mg92,00€25mg178,00€50mg295,00€100mg474,00€500mg1.035,00€1mL*10mM (DMSO)84,00€Glutaminase C-IN-1
CAS:Glutaminase C-IN-1 (Compound 968) is a Glutaminase C allosteric inhibitor.Formula:C27H27BrN2OPurezza:99.68% - >99.99%Colore e forma:SolidPeso molecolare:475.42Ref: TM-T3964
2mg42,00€5mg60,00€10mg87,00€25mg162,00€50mg273,00€100mg378,00€200mg557,00€1mL*10mM (DMSO)67,00€CGS 27023A
CAS:CGS 27023A is a non-peptidic, potent, and orally active stromelysin inhibitor.Formula:C18H24ClN3O5SPurezza:99.08%Colore e forma:SolidPeso molecolare:429.92Ledipasvir hydrochloride
CAS:Ledipasvir hydrochloride, a hepatitis C NS5A inhibitor, has EC50 of 34 pM (1a) and 4 pM (1b), also inhibits SARS-CoV 3CL pro (IC50 1.62 µM).Formula:C49H55ClF2N8O6Colore e forma:SolidPeso molecolare:925.46Grazoprevir
CAS:Grazoprevir (MK-5172) is a protease inhibitor targeting hepatitis C virus NS3/4A used for treating chronic HCV genotypes 1 or 4 infections. Cost-effective and quality-assured.Formula:C38H50N6O9SPurezza:99.36% - >99.99%Colore e forma:SolidPeso molecolare:766.9STK16-IN-1
CAS:STK16-IN-1 is an inhibitor of STK16 kinase (IC50: 295 nM).Formula:C17H12FN3OPurezza:99.52%Colore e forma:SolidPeso molecolare:293.3L-Albizziin
CAS:L-Albizziin (L-beta-Ureidoalanine) is a glutamase inhibitor and is a glutaminyl-tRNA synthetase inhibitor.Formula:C4H9N3O3Purezza:99.98%Colore e forma:White PowderPeso molecolare:147.13Anagliptin
CAS:Anagliptin (SK-0403) is a potent Inhibitor of DPP-4(IC50 of 3.8 nM), for the treatment of type 2 diabetes mellitus.Formula:C19H25N7O2Purezza:97.59% - 99.98%Colore e forma:SolidPeso molecolare:383.45Ref: TM-T7133
1mg44,00€5mg96,00€10mg130,00€25mg212,00€50mg314,00€100mg477,00€200mg677,00€1mL*10mM (DMSO)92,00€T-26c
CAS:T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor (IC50: 6.75 pM).Formula:C24H21N3O6SPurezza:>99.99%Colore e forma:SolidPeso molecolare:479.51Ref: TM-T5361
1mg46,00€2mg60,00€5mg90,00€10mg144,00€25mg236,00€50mg403,00€100mg582,00€1mL*10mM (DMSO)92,00€TAPI-1 trifluoroacetate (163847-77-6(free base))
TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.Formula:C28H38F3N5O7Purezza:98.06%Colore e forma:SolidPeso molecolare:613.62Picolamine
CAS:Picolamine acts as a potential inhibitor of DPP-4.Formula:C6H8N2Purezza:98.3%Colore e forma:Light Yellow LiquidPeso molecolare:108.14SB-3CT
CAS:SB-3CT is a potent and specific gelatinase inhibitor for MMP-2(Ki=13.9 nM) and MMP-9(Ki=600 nM).Formula:C15H14O3S2Purezza:98% - 99.38%Colore e forma:SolidPeso molecolare:306.4Ref: TM-T2009
1mg46,00€2mg62,00€5mg94,00€10mg150,00€25mg234,00€50mg349,00€100mg518,00€500mg1.134,00€1mL*10mM (DMSO)94,00€GK921
CAS:GK921 is a transglutaminase 2 (TGase) inhibitor.Formula:C21H20N4OPurezza:97.44% - 99.49%Colore e forma:SolidPeso molecolare:344.41Clemizole
CAS:Clemizole is an H1 histamine receptor antagonist, can inhibit NS4B's RNA binding and hepatitis C virus (HCV) replication.Formula:C19H20ClN3Purezza:98% - 99.65%Colore e forma:SolidPeso molecolare:325.84Ref: TM-T1822
1mg42,00€5mg82,00€10mg101,00€25mg152,00€50mg256,00€100mg460,00€500mg973,00€1mL*10mM (DMSO)93,00€Omarigliptin
CAS:Omarigliptin is a potent and selective oral dipeptidyl peptidase 4 (DPP4) inhibitor with IC50 value of 1.6 nM. Cost-effective and quality-assured.Formula:C17H20F2N4O3SPurezza:99.68% - 99.77%Colore e forma:SolidPeso molecolare:398.43Ref: TM-T2316
1mg38,00€2mg50,00€5mg80,00€10mg117,00€25mg200,00€50mg333,00€100mg477,00€500mg1.063,00€1mL*10mM (DMSO)131,00€CTTHWGFTLC, CYCLIC acetate(244082-19-7 free base)
CTTHWGFTLC, CYCLIC acetate is an inhibitor for matrix metalloproteinases (MMP)-2 and MMP-9.Formula:C54H75N13O16S2Purezza:99.71%Colore e forma:SolidPeso molecolare:1226.39Dabigatran
CAS:Dabigatran (BIBR 953ZW), a thrombin inhibitor, prevents thrombus formation, reducing stroke and embolism risk in nonvalvular atrial fibrillation patients.Formula:C25H25N7O3Purezza:97.44% - 98.7%Colore e forma:Tan SolidPeso molecolare:471.51JNJ0966
CAS:JNJ0966 is a highly selective MMP-9 zymogen inhibitor (IC50: 440 nM).Formula:C16H16N4O2S2Purezza:99.46% - 99.62%Colore e forma:SolidPeso molecolare:360.45Ref: TM-T4783
2mg34,00€5mg46,00€10mg64,00€25mg126,00€50mg219,00€100mg315,00€200mg434,00€1mL*10mM (DMSO)35,00€TCH-165
CAS:TCH-165 boosts 20S proteasome levels, enhancing IDP breakdown.Formula:C39H37N3O3Purezza:98.2% - 98.75%Colore e forma:SolidPeso molecolare:595.73Ref: TM-T17011
1mg71,00€5mg152,00€10mg236,00€25mg432,00€50mg647,00€100mg888,00€200mg1.198,00€1mL*10mM (DMSO)193,00€2-Cyanopyrimidine
CAS:2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)Formula:C5H3N3Purezza:99.27%Colore e forma:Crystalline SolidPeso molecolare:105.1MMP-9-IN-1
CAS:MMP-9-IN-1 is an inhibitor of specific matrix metalloproteinase-9 (MMP-9).Formula:C16H17F2N3O3SPurezza:99.21% - 99.86%Colore e forma:SolidPeso molecolare:369.39Ref: TM-T8310
2mg71,00€5mg105,00€10mg167,00€25mg326,00€50mg497,00€100mg708,00€200mg964,00€1mL*10mM (DMSO)117,00€(R)-MG-132
CAS:(R)-MG-132 (Z-Leu-D-leu-leu-al) is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132.Formula:C26H41N3O5Purezza:99.90%Colore e forma:SolidPeso molecolare:475.62Ref: TM-T12628
2mg38,00€5mg57,00€10mg79,00€25mg120,00€50mg177,00€100mg268,00€200mg398,00€1mL*10mM (DMSO)71,00€KKI-5 acetate(97145-43-2 free base)
KKI-5 acetate: Serine protease inhibitor, targets kallikrein/plasmin, potential anticancer and angioedema therapy.Formula:C37H59N11O11Purezza:99.44%Colore e forma:SolidPeso molecolare:833.95Tris(4-aminophenyl)methane
CAS:Tris(4-aminophenyl)methane (Leucopararosaniline), a triphenylmethane dye, is a weak HCV helicase inhibitor.Formula:C19H19N3Purezza:95.73%Colore e forma:Beige Solid CrystallinePeso molecolare:289.377-benzyl-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS:7-benzyl-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a inhibitor of Hepatitis C Virus(HCV).Formula:C15H16N4Purezza:99.22%Colore e forma:SolidPeso molecolare:252.31S 3304
CAS:S 3304 is a novel matrix metalloproteinases inhibitor which is specific for MMP-2 and MMP-9.Formula:C24H20N2O4S2Purezza:98.09%Colore e forma:SolidPeso molecolare:464.56Ref: TM-T16966
1mg42,00€2mg60,00€5mg105,00€10mg170,00€25mg281,00€50mg395,00€100mg537,00€200mg725,00€1mL*10mM (DMSO)108,00€Velpatasvir
CAS:Velpatasvir (GS-5816), also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor.Formula:C49H54N8O8Purezza:99.17% - 99.83%Colore e forma:SolidPeso molecolare:883Ref: TM-T3334
5mg34,00€10mg49,00€25mg79,00€50mg98,00€100mg152,00€200mg219,00€500mg358,00€1mL*10mM (DMSO)54,00€Avatrombopag
CAS:Avatrombopag (YM477) is a new oral thrombopoietin (TPO) receptor agonist, activating TPO receptor and increasing megakaryocytic proliferation/differentiationFormula:C29H34Cl2N6O3S2Purezza:99.01% - 99.63%Colore e forma:SolidPeso molecolare:649.65Ref: TM-T7417
1mg57,00€5mg120,00€10mg187,00€25mg339,00€50mg540,00€100mg747,00€200mg1.035,00€1mL*10mM (DMSO)167,00€Efegatran
CAS:Efegatran is a hematologic agent and platelet aggregation inhibitor.
Formula:C21H32N6O3Colore e forma:SolidPeso molecolare:416.52Daclatasvir dihydrochloride
CAS:Daclatasvir dihydrochloride is an oral antiviral that treats chronic hepatitis C by inhibiting HCV's NS5A; rare liver enzyme elevation, seldom causes jaundice.Formula:C40H52Cl2N8O6Purezza:99.67%Colore e forma:SolidPeso molecolare:811.8Ref: TM-T1786
1g230,00€5mg39,00€10mg48,00€25mg57,00€50mg67,00€100mg77,00€500mg161,00€1mL*10mM (DMSO)49,00€NSC 405020
CAS:NSC 405020 is a noncatalytic inhibitor of MT1-MMP.Formula:C12H15Cl2NOPurezza:96.93% - 99.07%Colore e forma:SolidPeso molecolare:260.16Saxagliptin
CAS:Saxagliptin (BMS-477118) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.Formula:C18H25N3O2Purezza:99.17% - 99.95%Colore e forma:SolidPeso molecolare:315.414-Butylresorcinol
CAS:4-Butylresorcinol (Butylresorcinol) is a potent inhibitor of tyrosinase(IC50 : 11.27 μM), and is used in cosmetics as a depigmenting agent.Formula:C10H14O2Purezza:99.48% - ≥95%Colore e forma:Light Beige Solid PowderPeso molecolare:166.22Paritaprevir
CAS:Paritaprevir (ABT450) 是一种非结构蛋白 3/4A 蛋白酶抑制剂，对 HCV 1a 和 HCV 1b 的 EC50 值分别为 1 和 0.21 nM。它也是SARS-CoV 3CLpro 的抑制剂，IC50为 1.31 μM。
Formula:C40H43N7O7SPurezza:99.72%Colore e forma:SolidPeso molecolare:765.88Tenofovir alafenamide hemifumarate
CAS:Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir.
Formula:C21H29N6O5PC4H4O4Purezza:99.33% - 99.96%Colore e forma:SolidPeso molecolare:534.51MUN57694
CAS:MUN57694 is an inhibitor of 26S proteasome.Formula:C23H25N3O4Purezza:99%Colore e forma:SolidPeso molecolare:407.46Ref: TM-T9090
2mg35,00€5mg52,00€10mg86,00€25mg145,00€50mg210,00€100mg296,00€200mg414,00€1mL*10mM (DMSO)64,00€Anagliptin hydrochloride
CAS:Anagliptin (SK-0403) hydrochloride: potent, selective oral DPP-4 inhibitor; IC50: DPP-4 3.8 nM, DPP-8 68 nM, DPP-9 60 nM.Formula:C19H26ClN7O2Colore e forma:SolidPeso molecolare:419.91Glecaprevir
CAS:Glecaprevir (ABT-493) is an HCV NS3/4A protease inhibitor, (IC50s: 3.5-11.3 nM).Formula:C38H46F4N6O9SPurezza:99.16% - 99.69%Colore e forma:SolidPeso molecolare:838.87MDL-28170
CAS:MDL-28170 (Calpain Inhibitor III) is a Cysteine protease.Formula:C22H26N2O4Purezza:95.06%Colore e forma:SolidPeso molecolare:382.45Ref: TM-T2470
1mg34,00€2mg49,00€5mg71,00€10mg90,00€25mg128,00€50mg167,00€100mg284,00€1mL*10mM (DMSO)75,00€GSK-A1
CAS:GSK-A1 is a specific inhibitor of PI4KA, also inhibited calcium-driven PRL secretion without affecting calcium signaling and Prl expression.Formula:C29H27FN6O4SPurezza:97.97% - 98.97%Colore e forma:SolidPeso molecolare:574.63SB-734117
CAS:SB-734117 inhibits productive replication of several HCMV strains.Formula:C14H16N6OPurezza:99.72%Colore e forma:SolidPeso molecolare:284.32Ref: TM-T9580
1mg109,00€5mg235,00€10mg349,00€25mg532,00€50mg745,00€100mg999,00€200mg1.333,00€1mL*10mM (DMSO)224,00€LY 3000328
CAS:LY 3000328 (Cathepsin S inhibitor) is a selective inhibitor of cathepsin S.Cost-effective and quality-assured.Formula:C25H29FN4O5Purezza:97.83% - 99.54%Colore e forma:SolidPeso molecolare:484.52Ref: TM-TQ0116
1mg90,00€2mg130,00€5mg198,00€10mg263,00€25mg462,00€50mg672,00€100mg945,00€1mL*10mM (DMSO)207,00€Sofosbuvir
CAS:Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatmentFormula:C22H29FN3O9PPurezza:99.77% - 99.82%Colore e forma:SolidPeso molecolare:529.45Lersivirine
CAS:Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy.Formula:C17H18N4O2Purezza:98.01%Colore e forma:SolidPeso molecolare:310.35
![7-benzyl-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT50024.webp&w=3840&q=75)
