CymitQuimica logo
Proteasi/Proteasoma

Proteasi/Proteasoma

Gli inibitori delle proteasi e del proteasoma sono composti che bloccano l'attività delle proteasi e del proteasoma, che sono coinvolti nella degradazione e nel turnover delle proteine. Questi inibitori sono fondamentali per studiare la regolazione dell'omeostasi proteica, il controllo del ciclo cellulare e l'apoptosi. Gli inibitori delle proteasi e del proteasoma vengono anche utilizzati nel trattamento di malattie come il cancro, dove la degradazione anomala delle proteine svolge un ruolo nella progressione della malattia. Inibendo le proteasi o il proteasoma, questi composti possono indurre la morte cellulare nelle cellule tumorali e sono strumenti critici sia per la ricerca di base che per lo sviluppo terapeutico. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle proteasi e del proteasoma di alta qualità per supportare la tua ricerca in biochimica, biologia cellulare e sviluppo di farmaci.

Sottocategorie di "Proteasi/Proteasoma"

Mostrare 3 più sottocategorie

Trovati 1092 prodotti di "Proteasi/Proteasoma"

Ordinare per
Purezza (%)
0
100
|
0
|
50
|
90
|
95
|
100
prodotti per pagina.
  • TAPI1 acetate
    Targetmol
    + Info

    TAPI1 acetate

    TAPI1 acetate (TNF-α processing inhibitor-1) is a TACE (ADAM17) inhibitor that inhibits shedding of TNF-α cytokine receptors; MMP inhibitor .
    Formula:C28H41N5O7
    Purezza:98.82% - 99.94%
    Colore e forma:Solid
    Peso molecolare:559.65

    Ref: TM-T6009L

  • HIV-1 TAT (48-60) Acetate
    Targetmol
    + Info

    HIV-1 TAT (48-60) Acetate

    Lilotomab (HH1) is a murine anti-CD37 antibody that can be used to synthesize anti-CD37 antibody-radionuclide couplings.
    Formula:C72H135N35O18
    Purezza:99.93%
    Colore e forma:Soild
    Peso molecolare:1779.07

    Ref: TM-T75964L

  • L-Methionine-DL-sulfoximine
    Targetmol
    + Info

    L-Methionine-DL-sulfoximine

    CAS:
    MSO blocks glutamine synthetase, impacts astroglia, and is used in convulsant research.
    Formula:C5H12N2O3S
    Purezza:99.56% - ≥98%
    Colore e forma:White Crystalline Powder
    Peso molecolare:180.23

    Ref: TM-T41299

  • Logo CymitQuimica
    Targetmol
    + Info

    Nostosin G

    Nostosin G, a linear peptide with Hpla, Hty, and argininal, inhibits trypsin effectively (IC50 = 0.1 μM).
    Formula:C25H33N5O6
    Colore e forma:Solid
    Peso molecolare:499.56

    Ref: TM-T75647

  • Logo CymitQuimica
    Targetmol
    + Info

    Proteasome-IN-7

    Proteasome-IN-7 (Compound 6f) is a macrolactam-based epoxyketone proteasome inhibitor with an IC50 value of 37.92 nM against the 20S proteasome ChT-L subunit. It exhibits potent antiproliferative effects on multiple myeloma, acute lymphoblastic leukemia, and non-small cell lung cancer.
    Formula:C48H56N6O10S
    Colore e forma:Solid
    Peso molecolare:909.06

    Ref: TM-T205355

  • α 1(I) Collagen (614-639), human
    Targetmol
    + Info

    α 1(I) Collagen (614-639), human

    CAS:
    This is a peptide inhibitor of collagen fibrillar matrix assembly.
    Formula:C134H189N37O39
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:2942.16

    Ref: TM-TP1643

  • Cys-TAT(47-57) acetate(583836-55-9 Free base)
    Targetmol
    + Info

    Cys-TAT(47-57) acetate(583836-55-9 Free base)

    Cys-TAT(47-57) acetate is derived from the HIV-1 transactivating protein. Cys-TAT(47-57) acetate is an arginine rich peptide that can penetrate cells.
    Formula:C69H128N34O16S
    Purezza:95.1100%
    Colore e forma:Solid
    Peso molecolare:1722.04

    Ref: TM-TP1185L

  • VD2173
    Targetmol
    + Info

    VD2173

    CAS:
    <p>VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.</p>
    Formula:C31H45N9O6S
    Colore e forma:Solid
    Peso molecolare:671.81

    Ref: TM-T74390

  • GSK2818713
    Targetmol
    + Info

    GSK2818713

    CAS:
    GSK2818713 is a novel Hepatitis C NS5A replication complex inhibitor.
    Formula:C46H56N8O8
    Colore e forma:Solid
    Peso molecolare:849.002

    Ref: TM-T38858

  • Logo CymitQuimica
    Targetmol
    + Info

    Stevia Powder

    Stevia Powder, a natural sweetener, possesses antioxidant properties. It regulates antifibrotic pathways in cirrhotic rats, demonstrated by a reduction in hepatic stellate cells and decreased expression of matrix metalloproteinases MMP2 and MMP13. Furthermore, it increases the antifibrotic molecule Smad7, which helps prevent the elevation of serum necrosis and bile retention markers, thereby inhibiting the progression of liver fibrosis.
    Colore e forma:Odour Solid

    Ref: TM-TN8189

  • 5-epi-Arvestonate A
    Targetmol
    + Info

    5-epi-Arvestonate A

    CAS:
    <p>5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.</p>
    Formula:C16H26O5
    Colore e forma:Solid
    Peso molecolare:298.37

    Ref: TM-T75535

  • Logo CymitQuimica
    Targetmol
    + Info

    RJS308

    <p>RJS308 is a PROTAC degrader of cyclosporin A (cyclosporin A) with a DC50 of 284 nM. It exhibits antiviral activity by inhibiting the replication of HIV-1 and HCV. (Pink: ligand for target protein CypA ligand-2; Black: linker; Blue: ligand for E3 ligase VHL (S,R,S)-AHPC-Me)</p>
    Formula:C63H75N13O11S
    Colore e forma:Solid
    Peso molecolare:1222.42

    Ref: TM-T205591

  • TMC647055 Choline salt
    Targetmol
    + Info

    TMC647055 Choline salt

    TMC647055 choline salt is a selective and cell-permeating inhibitor of HCV NS5B (IC50: 34 nM).
    Formula:C37H53N5O8S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:727.91

    Ref: TM-T13170

  • Logo CymitQuimica
    Targetmol
    + Info

    Cathepsin C-IN-6

    Cathepsin C-IN-6 (compound 2), an E-64c-hydrazideas-derived inhibitor of cathepsin C, possesses anti-inflammatory properties and impedes neutrophil elastase
    Formula:C24H35N5O4·xC2HF3O2
    Colore e forma:Solid

    Ref: TM-T79496

  • Sofosbuvir impurity J
    Targetmol
    + Info

    Sofosbuvir impurity J

    CAS:
    Sofosbuvir impurity J is an diastereoisomer of Sofosbuvir.Sofosbuvir is an HCV RNA replication inhibitor, with potent anti-hepatitis C virus activity.
    Formula:C22H30FN4O8P
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:528.47

    Ref: TM-T12965

  • 7-Methoxy obtusifolin
    Targetmol
    + Info

    7-Methoxy obtusifolin

    CAS:
    7-Methoxy obtusifolin (Compound 4) is a chemical compound that acts as a competitive inhibitor of the enzyme tyrosinase, displaying an inhibitory concentration
    Formula:C17H14O6
    Colore e forma:Solid
    Peso molecolare:314.29

    Ref: TM-T75613

  • PS 915
    Targetmol
    + Info

    PS 915

    CAS:
    PS 915 is a substrate for colorimetric assay. It was used for plasma antithrombin.
    Formula:C27H36ClN7O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:590.08

    Ref: TM-T24674

  • DPP-4-IN-14
    Targetmol
    + Info

    DPP-4-IN-14

    <p>DPP-4-IN-14 (compound 30) is an inhibitor of DPP-4, with an IC50 value of 12.82 nM.</p>
    Formula:C33H27N7O3
    Colore e forma:Solid
    Peso molecolare:569.613

    Ref: TM-T204855

  • Logo CymitQuimica
    Targetmol
    + Info

    Rivulariapeptolides 988

    Rivulariapeptolides 988 inhibits serine proteases: chymotrypsin (IC50 = 95.46 nM), elastase (15.29 nM), proteinase K (85.50 nM).
    Formula:C50H68N8O13
    Colore e forma:Solid
    Peso molecolare:989.12

    Ref: TM-T75651

  • Logo CymitQuimica
    Targetmol
    + Info

    Ecallantide TFA

    Ecallantide (DX-88) TFA, a specific recombinant plasma kallikrein inhibitor, directly inhibits bradykinin production and is indicated for the prevention of
    Colore e forma:Odour Solid

    Ref: TM-T82510