Proteasi/Proteasoma
Gli inibitori delle proteasi e del proteasoma sono composti che bloccano l'attività delle proteasi e del proteasoma, che sono coinvolti nella degradazione e nel turnover delle proteine. Questi inibitori sono fondamentali per studiare la regolazione dell'omeostasi proteica, il controllo del ciclo cellulare e l'apoptosi. Gli inibitori delle proteasi e del proteasoma vengono anche utilizzati nel trattamento di malattie come il cancro, dove la degradazione anomala delle proteine svolge un ruolo nella progressione della malattia. Inibendo le proteasi o il proteasoma, questi composti possono indurre la morte cellulare nelle cellule tumorali e sono strumenti critici sia per la ricerca di base che per lo sviluppo terapeutico. Presso CymitQuimica, offriamo una vasta gamma di inibitori delle proteasi e del proteasoma di alta qualità per supportare la tua ricerca in biochimica, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Proteasi/Proteasoma"
- Acetil-CoA carbossilasi(36 prodotti)
- Cisteina proteasi(110 prodotti)
- DPP-4(20 prodotti)
- Glutaminasi(44 prodotti)
- Proteasi HIV(502 prodotti)
- PAI-1(25 prodotti)
- Inibitori della proteasi(50 prodotti)
- Ricettore attivato dalla proteasi(54 prodotti)
- Proteasoma(95 prodotti)
- Proteasi serina(56 prodotti)
- p97(15 prodotti)
Mostrare 3 più sottocategorie
Trovati 1092 prodotti di "Proteasi/Proteasoma"
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Z-FG-NHO-BzOME
CAS:<p>Z-FG-NHO-BzOME is a chemical compound functioning as a cysteine protease inhibitor, selectively targeting and inhibiting cathepsin B, cathepsin L, cathepsin S,</p>Formula:C27H27N3O7Colore e forma:SolidPeso molecolare:505.52KB-R7785
CAS:KB-R7785 is a novel ADAM12/MMP inhibitor improving heart function and insulin sensitivity by blocking HB-EGF and TNF-alpha.Formula:C18H27N3O4Colore e forma:SolidPeso molecolare:349.42MDL 101146
CAS:MDL 101146 is an orally active neutrophil elastase inhibitor.Formula:C29H37F5N4O6Purezza:98%Colore e forma:SolidPeso molecolare:632.62Mergetpa
CAS:Mergetpa, a carboxypeptidase inhibitor, impedes the conversion of kinins and B2 receptor antagonists into metabolites devoid of the C-terminal arginine [1].Formula:C7H15N3O2S2Purezza:98%Colore e forma:SolidPeso molecolare:237.34O-Benzoylhydroxylamine
CAS:O-Benzoyl hydroxylamine exhibits properties as a dipeptidyl peptidase-IV (DPP-IV) inhibitor and demonstrates antidiabetic effects[1].Formula:C7H7NO2Colore e forma:SolidPeso molecolare:137.14Neurodegenerative Disorder-Targeting Compound 1
CAS:<p>Neurodegenerative Disorder-Targeting Compound 1 is an inhibitor of calpain [1].</p>Formula:C28H28N4O4Purezza:98%Colore e forma:SolidPeso molecolare:484.55MMP-145
CAS:MMP-145 is used as a protease inhibitor.Formula:C20H20N2O7SPurezza:98%Colore e forma:SolidPeso molecolare:432.45BMS-189664
CAS:BMS-189664 is an inhibitor of thrombin.Formula:C22H34N6O4SPurezza:98%Colore e forma:SolidPeso molecolare:478.61MMP-3 Inhibitor VIII
CAS:Matrix metalloproteinase-3 (MMP-3), also known as stromelysin-1, is a critical enzyme involved in tissue remodeling and repair through its role in degrading extracellular matrix proteins, facilitating cell migration. This enzyme has been implicated in various physiological processes including vascular remodeling associated with aneurysm formation, wound healing, the progression of atherosclerosis, and tumor initiation. MMP-3 inhibitor VIII, a cell-permeable sulfonamide-based hydroxamic acid, effectively inhibits MMP-3 by binding to its active site (Ki = 23 nM), thus blocking its enzymatic activity. Additionally, this inhibitor has been demonstrated to suppress the activity of mouse macrophage metalloelastase MME/MMP-12, with an IC50 value of 13 nM, highlighting its potential utility in research on tissue remodeling and disease processes involving MMPs.Formula:C20H26N2O5SColore e forma:SolidPeso molecolare:406.5GSK-625433
CAS:GSK-625433: Homochiral inhibitor blocks HCV genotypes 1a/1b polymerase.Formula:C26H32N4O5SColore e forma:SolidPeso molecolare:512.62Proteasome-IN-5
CAS:<p>Proteasome-IN-5, also known as compound 5, acts as a proteasome inhibitor [1].</p>Formula:C20H30BN5O7Purezza:98%Colore e forma:SolidPeso molecolare:463.29Dim16
CAS:Dim16, a dual inhibitor of PCSK9/HMG-CoAR, demonstrates potent activity with an IC50 of 19 nM against PCSK9 and significantly impedes PCSK9-LDLR interactionFormula:C29H38IN5Colore e forma:SolidPeso molecolare:583.55HCV-IN-43
CAS:HCV-IN-43 (compound 2), an HCV NS5B protein inhibitor, efficiently inhibits HCV virus replication and is utilized in the study of HCV infection [1].Formula:C26H26FN3O5SColore e forma:SolidPeso molecolare:511.57M867
CAS:M867 is a selective, reversible caspase-3 inhibitor, possessing an IC50 of 1.4 nM and a Ki value of 0.7 nM, demonstrating anti-apoptotic activity [1].Formula:C27H43N7O6Purezza:98%Colore e forma:SolidPeso molecolare:561.67Proteasome β2c/i-IN-1
CAS:Proteasome β2c/i-IN-1 (compound 37) serves as a selective inhibitor targeting the β2c and β2i subunits of the human proteasome [1].Formula:C32H48N4O7Purezza:98%Colore e forma:SolidPeso molecolare:600.75EP1013
CAS:EP1013 is a broad-spectrum selective inhibitor of Caspase used in the study of type 1 diabetes.Formula:C18H23FN2O6Purezza:98%Colore e forma:SolidPeso molecolare:382.38NK3201
CAS:NK3201, a specific chymase inhibitor, suppresses bleomycin-induced pulmonary fibrosis in hamsters.Formula:C31H29N5O6Purezza:98%Colore e forma:SolidPeso molecolare:567.59Beclabuvir HCl
CAS:Beclabuvir (BMS-791325) is an HCV inhibitor targeting NS5B polymerase with sub-28 nM potency for genotypes 1, 3, 4, 5.Formula:C36H46ClN5O5SColore e forma:SolidPeso molecolare:696.3Paltimatrectinib
CAS:Paltimatrectinib (PBI-200) is a tyrosine kinase inhibitor with anticancer activity, and is used in the study of bladder, breast, and colorectal cancers.Formula:C20H15F5N6Purezza:99.96%Colore e forma:SolidPeso molecolare:434.37MMP3 inhibitor 1
CAS:MMP3 inhibitor 1 is a potent and highly selective inhibitor of MMP-3 (IC50 of 1 nM).Formula:C23H31N3O6SPurezza:98%Colore e forma:SolidPeso molecolare:477.57
