Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1491 prodotti di "Autofagia"
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Oxidopamine hydrobromide
CAS:Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.Formula:C8H12BrNO3Purezza:98.22% - 99.88%Colore e forma:Beige To Brown Fine Crystalline PowderPeso molecolare:250.09MLi-2
CAS:MLi-2: Novel, potent CNS-active LRRK2 inhibitor; IC50s: 0.76nM in vitro, 1.4nM cellular, 3.4nM binding.Formula:C21H25N5O2Purezza:98.96%Colore e forma:SolidPeso molecolare:379.46Ref: TM-T16115
1mg55,00€2mg84,00€5mg126,00€10mg178,00€25mg409,00€50mg618,00€100mg880,00€1mL*10mM (DMSO)135,00€Cytarabine
CAS:Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).Formula:C9H13N3O5Purezza:99.83% - 99.93%Colore e forma:Fine Off-White Crystalline PowderPeso molecolare:243.22Mevastatin
CAS:Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.Formula:C23H34O5Purezza:99.12%Colore e forma:White-Yellowish To Yellow Powder Solid PowderPeso molecolare:390.51Ketanserin
CAS:Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.Formula:C22H22FN3O3Purezza:99.19% - 99.73%Colore e forma:SolidPeso molecolare:395.43Glibenclamide
CAS:Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.Formula:C23H28ClN3O5SPurezza:99.05% - 99.75%Colore e forma:SolidPeso molecolare:494.00Thalidomide
CAS:Thalidomide, a glutamic acid derivative, has teratogenic and immunomodulatory effects.Formula:C13H10N2O4Purezza:98.88% - 99.88%Colore e forma:White SolidPeso molecolare:258.23Chenodeoxycholic acid
CAS:Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. High-Quality, Low-Cost!
Formula:C24H40O4Purezza:99.70% - 99.93%Colore e forma:White - Almost White Solid PowderPeso molecolare:392.57Dexamethasone
CAS:Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.Formula:C22H29FO5Purezza:98% - 99.91%Colore e forma:Crystals From Ether (Ntp 1992)Peso molecolare:392.46Phenformin hydrochloride
CAS:Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.Formula:C10H16ClN5Purezza:97.11% - 99.80%Colore e forma:Lactic AcidosisPeso molecolare:241.72Spironolactone
CAS:Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.Formula:C24H32O4SPurezza:99.87%Colore e forma:White PowderPeso molecolare:416.57Doxorubicin hydrochloride
CAS:Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).Formula:C27H29NO11·HClPurezza:98% - 99.52%Colore e forma:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Peso molecolare:579.99Trimetazidine dihydrochloride
CAS:Trimetazidine, an anti-ischemic agent, enhances myocardial glucose use, inhibits fat metabolism, and helps with angina.Formula:C14H24Cl2N2O3Purezza:99.58%Colore e forma:Crystalline SolidPeso molecolare:339.258Hydroxyurea
CAS:Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.Formula:CH4N2O2Purezza:99.85% - 99.92%Colore e forma:SolidPeso molecolare:76.05Raloxifene hydrochloride
CAS:Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.Formula:C28H28ClNO4SPurezza:98% - 99.97%Colore e forma:Light Yellow SolidPeso molecolare:510.044Avermectin B1
CAS:Avermectin B1 is served as anthelmintic and insecticide.Formula:C48H72O14Purezza:mixture - mixtureColore e forma:White PowderPeso molecolare:873.09Doxazosin mesylate
CAS:Doxazosin mesylate (UK 33274 mesylate)(UK 33274) is a quinazoline-derivative. It is a selectively antagonizes postsynaptic α1-adrenergic receptors.Formula:C24H29N5O8SPurezza:99.92%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:547.58Pictilisib dimethanesulfonate
CAS:Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) andFormula:C25H35N7O9S4Purezza:99.63%Colore e forma:SolidPeso molecolare:705.85Reserpine
CAS:Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.Formula:C33H40N2O9Purezza:98.85% - 99.99%Colore e forma:White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)Peso molecolare:608.68Lapatinib Ditosylate
CAS:Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).Formula:C29H26ClFN4O4S·2C7H8O3SPurezza:99.41%Colore e forma:Yellow SolidPeso molecolare:925.46
