Autofagia
Gli inibitori dell'autofagia mirano al processo cellulare di autofagia, che comporta la degradazione e il riciclo dei componenti cellulari attraverso i lisosomi. L'autofagia è un meccanismo critico per mantenere l'omeostasi cellulare, ma la sua disfunzione è implicata in varie malattie, tra cui il cancro, la neurodegenerazione e le infezioni. Gli inibitori dell'autofagia possono bloccare questo processo, rendendoli strumenti preziosi per studiare il ruolo dell'autofagia nelle malattie e sviluppare strategie terapeutiche. Presso CymitQuimica, offriamo inibitori dell'autofagia per supportare la tua ricerca in biologia cellulare, oncologia e malattie neurodegenerative.
Trovati 1489 prodotti di "Autofagia"
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4,4'-Dimethoxychalcone
CAS:4,4'-Dimethoxychalcone (4,4-Dimethoxychalcone) is a natural product.Formula:C17H16O3Purezza:99.57%Colore e forma:SolidPeso molecolare:268.31Ref: TM-T7985
2mg35,00€5mg49,00€10mg65,00€25mg92,00€50mg147,00€100mg227,00€200mg335,00€1mL*10mM (DMSO)Prezzo su richiestaHoechst 33342 trihydrochloride
CAS:Hoechst 33342 trihydrochloride (bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride) is a membrane permeant DNA stain with blue fluorescence.Formula:C27H31Cl3N6OPurezza:98.73% - ≥98%Colore e forma:SolidPeso molecolare:561.93Ixazomib citrate
CAS:Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).Formula:C20H23BCl2N2O9Purezza:98.37% - >99.99%Colore e forma:SolidPeso molecolare:517.12MG-132
CAS:<p>MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor, cell-permeable and reversible,an autophagy activator, induces apoptosis. High-Quality, Low-Cost!</p>Formula:C26H41N3O5Purezza:95% - 99.99%Colore e forma:White To Off-White PowderPeso molecolare:475.62Vps34-IN-1
CAS:Vps34-IN-1: potent, selective Vps34 inhibitor, 25 nM IC50, spares class I/II PI3Ks.Formula:C21H24ClN7OPurezza:97.04%Colore e forma:SolidPeso molecolare:425.91Ref: TM-T7015
1mg46,00€2mg59,00€5mg93,00€10mg131,00€25mg219,00€50mg350,00€100mg505,00€1mL*10mM (DMSO)92,00€SAR405
CAS:SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor effects on cancer cells.Formula:C19H21ClF3N5O2Purezza:99.42% - 99.79%Colore e forma:SolidPeso molecolare:443.85AZ304
CAS:AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).Formula:C27H25N5O2Purezza:99.82%Colore e forma:SolidPeso molecolare:451.52KB-R7943 mesylate
CAS:KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.Formula:C17H21N3O6S2Purezza:99.88% - ≥95%Colore e forma:SolidPeso molecolare:427.5Briciclib
CAS:Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.Formula:C19H23O10PSPurezza:98% - 99.84%Colore e forma:SolidPeso molecolare:474.42Ref: TM-T3207
1mg47,00€2mg57,00€5mg88,00€10mg126,00€25mg250,00€50mg376,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)87,00€Hoechst 33342
CAS:Hoechst 33342 (bisBenzimide H 33342) is a benzimidazole fluorescent dye and a cell-permeable fluorescent DNA dye. High-Quality, Low-Cost!Formula:C27H28N6OPurezza:98.12% - 99.75%Colore e forma:Yellow-Green PowderPeso molecolare:452.55Brevilin A
CAS:Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.Formula:C20H26O5Purezza:99.97% - >99.99%Colore e forma:SolidPeso molecolare:346.42Ref: TM-T4672
1mg96,00€5mg215,00€10mg369,00€25mg610,00€50mg840,00€100mg1.130,00€500mg2.308,00€1mL*10mM (DMSO)235,00€Actein
CAS:Actein stimulates bone formation, counters osteoporosis and oxidative damage, and may treat lipid disorders and cancer, inhibiting breast cancer cell growth.Formula:C37H56O11Purezza:≥98%Colore e forma:Brown PowderPeso molecolare:676.83Tempol
CAS:Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.Formula:C9H18NO2Purezza:97% - 99.98%Colore e forma:4-Hydroxy-Tempo Appears As Orange Flakes Solid FlakesPeso molecolare:172.25Peretinoin
CAS:Peretinoin (NIK333) is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as RXR and RAR.Formula:C20H30O2Purezza:97.23%Colore e forma:SolidPeso molecolare:302.45Ref: TM-TQ0064
1mg40,00€2mg51,00€5mg88,00€10mg126,00€25mg230,00€50mg401,00€100mg597,00€500mg1.283,00€1mL*10mM (DMSO)87,00€LC3-mHTT-IN-AN2
CAS:LC3-mHTT-IN-AN2 (5,7-Dihydroxy-4-phenylcoumarin) is found in the plant Passiflora serratodigitata with the antibacterial activity.Formula:C15H10O4Purezza:98.82% - ≥98%Colore e forma:SolidPeso molecolare:254.24Rabusertib
CAS:<p>Rabusertib (IC-83) is a chk1 inhibitor in trials for various cancers, including pancreatic and non-small cell lung cancer.</p>Formula:C18H22BrN5O3Purezza:98.86% - 99.87%Colore e forma:SolidPeso molecolare:436.3SN-38
CAS:SN-38 (NK012) is the active metabolite of Irinotecan, a DNA topoisomerase I (Topo I) inhibitor, which inhibits DNA and RNA synthesis (IC50=0.077/1.3 μM).Formula:C22H20N2O5Purezza:98% - 99.97%Colore e forma:Light-Yellow SolidPeso molecolare:392.4AS1842856
CAS:AS1842856 is a Foxo1 inhibitor that blocks the transcriptional activity of Foxo1. AS1842856 has autophagy inhibitory activity. Cost-effective and quality-assured.Formula:C18H22FN3O3Purezza:99.36% - >99.99%Colore e forma:SolidPeso molecolare:347.38DMH-1
CAS:<p>DMH-1 is a BMP inhibitor that inhibits ALK1, ALK2, ALK3 and ALK6. DMH-1 promotes pluripotent stem cell differentiation. Cost-effective and quality-assured.</p>Formula:C24H20N4OPurezza:98% - 99.92%Colore e forma:SolidPeso molecolare:380.44SP600125
CAS:SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitiveFormula:C14H8N2OPurezza:97.63% - 99.82%Colore e forma:SolidPeso molecolare:220.23Pexmetinib
CAS:Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.Formula:C31H33FN6O3Purezza:99.07% - 99.66%Colore e forma:SolidPeso molecolare:556.63Vps34-IN-4
CAS:VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM)Formula:C21H25N7OPurezza:98.6%Colore e forma:SolidPeso molecolare:391.47Ref: TM-T7944
1mg66,00€5mg144,00€10mg227,00€25mg399,00€50mg567,00€100mg753,00€200mg1.035,00€1mL*10mM (DMSO)159,00€XCT790
CAS:XCT790 is a potent, selective and inverse agonist of estrogen-related receptor alpha(ERRα).Formula:C23H13F9N4O3SPurezza:99% - 99.61%Colore e forma:SolidPeso molecolare:596.4220-DEOXYINGENOL
CAS:20-DEOXYINGENOL is a natual product.Formula:C20H28O4Purezza:99.98% - ≥95%Colore e forma:SolidPeso molecolare:332.43Ref: TM-T5689
1mg37,00€5mg69,00€10mg88,00€25mg144,00€50mg205,00€100mg303,00€200mg445,00€1mL*10mM (DMSO)77,00€U0126
CAS:U0126, an effective and selective non-competitive inhibitor of MAP kinase, inhibits MEK-1 and MEK-2 with IC50 values of 0.07 and 0.06 μM respectively.Formula:C18H16N6S2Purezza:99.61%Colore e forma:White SolidPeso molecolare:380.49Torin 1
CAS:Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.Formula:C35H28F3N5O2Purezza:98.3% - 99.33%Colore e forma:SolidPeso molecolare:607.62Clinofibrate
CAS:Clinofibrate lowers lipids, blocks HMGCR (IC50: 0.47 mM), and controls cholesterol/triacylglycerides.Formula:C28H36O6Purezza:>99.99%Colore e forma:White Crystalline PowderPeso molecolare:468.58Alginic acid
CAS:Alginic acid, a polysaccharide from brown seaweed, has anti-anaphylactic and anti-inflammatory properties and is used in food industry.Formula:C14H22O13Purezza:≥98%Colore e forma:SolidPeso molecolare:398.317Tetrahydrocurcumin
CAS:Tetrahydrocurcumin (HZIV 81-2), a major metabolite of curcumin, has strong antioxidant and cardioprotective properties.Formula:C21H24O6Purezza:97.81% - 98.82%Colore e forma:Solid PowderPeso molecolare:372.41Salbutamol hemisulfate
CAS:Salbutamol hemisulfate (Albuterol Sulfate) is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 μM.Formula:C13H21NO3H2O4SPurezza:99.35%Colore e forma:White Or Almost White Odourless PowderPeso molecolare:576.70Acumapimod
CAS:Acumapimod (BCT-197) is an orally active inhibitor of p38α MAPK (IC50 <1 μM).Formula:C22H19N5O2Purezza:≥95%Colore e forma:SolidPeso molecolare:385.42Lithocholic acid
CAS:Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM). High-Quality, Low-Cost!Formula:C24H40O3Purezza:98% - 99.93%Colore e forma:Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)Peso molecolare:376.57Scutellarein
CAS:Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity.Formula:C15H10O6Purezza:98.02% - 99.63%Colore e forma:SolidPeso molecolare:286.24Ref: TM-T3319
2mg40,00€5mg56,00€10mg80,00€25mg115,00€50mg167,00€100mg240,00€200mg356,00€1mL*10mM (DMSO)63,00€Vancomycin
CAS:Vancomycin is a glycopeptide antibiotic that exerts its antimicrobial activity by altering the permeability of cell membranes and selectively inhibitingFormula:C66H75Cl2N9O24Purezza:98.76% - 99.52%Colore e forma:Almost White PowderPeso molecolare:1449.25URB-597
CAS:URB-597 (FAAH Inhibitor II) is an effective, orally bioavailable FAAH inhibitor (IC50: 4.6 nM), and no effect on other cannabinoid-related targets.Formula:C20H22N2O3Purezza:97.20% - 98.24%Colore e forma:SolidPeso molecolare:338.4Tropifexor
CAS:<p>Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM.</p>Formula:C29H25F4N3O5SPurezza:99.3% - 99.85%Colore e forma:SolidPeso molecolare:603.58Ref: TM-T4379
1mg87,00€5mg166,00€10mg248,00€25mg437,00€50mg665,00€100mg1.008,00€200mg1.520,00€500mg2.252,00€TG101209
CAS:TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.Formula:C26H35N7O2SPurezza:99% - >99.99%Colore e forma:SolidPeso molecolare:509.67Pifithrin-μ
CAS:Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.Formula:C8H7NO2SPurezza:99.33% - 99.79%Colore e forma:SolidPeso molecolare:181.21Valinomycin
CAS:Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes ParkinFormula:C54H90N6O18Purezza:95.37% - 97.16%Colore e forma:White SolidPeso molecolare:1111.32Eupatilin
CAS:Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.Formula:C18H16O7Purezza:98.53% - 99%Colore e forma:SolidPeso molecolare:344.32LYN-1604
CAS:<p>LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.</p>Formula:C33H43Cl2N3O2Purezza:98%Colore e forma:SolidPeso molecolare:584.62SR9009
CAS:SR9009, a REV-ERB agonist, modulates genes and circadian rhythms, reducing fat mass and improving metabolism in obese mice.Formula:C20H24ClN3O4SPurezza:99.94% - >99.99%Colore e forma:SolidPeso molecolare:437.94Ref: TM-T3685
2mg42,00€5mg62,00€10mg87,00€25mg144,00€50mg250,00€100mg405,00€200mg600,00€1mL*10mM (DMSO)67,00€Kaempferol
CAS:<p>Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ.</p>Formula:C15H10O6Purezza:98% - 99.41%Colore e forma:Yellow Needles From Alcohol And Water SolidPeso molecolare:286.24DPN
CAS:DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .Formula:C15H13NO2Purezza:99.01%Colore e forma:Off-White SolidPeso molecolare:239.27Nutlin-3a
CAS:Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction. Nutlin-3a has antitumor activity. Cost-effective and quality-assured.Formula:C30H30Cl2N4O4Purezza:95.62% - 99.71%Colore e forma:SolidPeso molecolare:581.49Ref: TM-T6023
1mg49,00€2mg70,00€5mg96,00€10mg164,00€25mg268,00€50mg398,00€100mg587,00€1mL*10mM (DMSO)135,00€FIPI
CAS:<p>FIPI, a halopemide derivative, strongly blocks PLD1 and PLD2 (IC50s: 25 nM, 20 nM) and hinders PLD-mediated cell activity.</p>Formula:C23H24FN5O2Purezza:97.21% - 98.68%Colore e forma:SolidPeso molecolare:421.47Quercitrin
CAS:Quercitrin (3-rhamnosyl quercetin) is a plant-derived flavonoid compound, displays antioxidant and anti-inflammatory activities.Formula:C21H20O11Purezza:98.89% - 99.66%Colore e forma:Yellow Crystals From Dil Methanol Or Ethanol SolidPeso molecolare:448.38Quisinostat dihydrochloride
CAS:Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) 是一种有口服活性，高效的 pan-HDAC 抑制剂，具有广泛的抗肿瘤活性。它对 HDAC1、HDAC2、HDAC4、HDAC10和HDAC11 的IC50值分别为 0.11 nM、0.33 nM、0.64 nM、0.46 nM 和 0.37 nM。Formula:C21H28Cl2N6O2Purezza:97.13%Colore e forma:SolidPeso molecolare:467.39Ref: TM-T6865
1mg65,00€5mg127,00€10mg180,00€25mg309,00€50mg434,00€100mg605,00€200mg852,00€1mL*10mM (DMSO)130,00€3-Bromopyruvic acid
CAS:<p>3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition.</p>Formula:C3H3BrO3Purezza:95% - 99.644%Colore e forma:White To Pale Yellow Crystalline PowderPeso molecolare:166.96Dioscin
CAS:Dioscin (Collettiside III) is a saponin with antitumor activities.Formula:C45H72O16Purezza:99.85% - 99.87%Colore e forma:SolidPeso molecolare:869.04Ref: TM-T6473
5mg35,00€10mgPrezzo su richiesta25mgPrezzo su richiesta50mg86,00€100mg111,00€200mgPrezzo su richiesta500mgPrezzo su richiesta1mL*10mM (DMSO)55,00€GLPG1837
CAS:GLPG1837 (ABBV-974) is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.Formula:C16H20N4O3SPurezza:99.64% - 99.91%Colore e forma:SolidPeso molecolare:348.42Neflamapimod
CAS:Neflamapimod (VX-745) , a specific and effective inhibitor of p38α(IC50=10 nM), is 22-fold greater specificity against p38β and no inhibition activity to p38γ.Formula:C19H9Cl2F2N3OSPurezza:97.88% - 99.75%Colore e forma:SolidPeso molecolare:436.26Turofexorate Isopropyl
CAS:<p>Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM</p>Formula:C25H24F2N2O3Purezza:98.55% - 99.73%Colore e forma:SolidPeso molecolare:438.47SGI-1776
CAS:SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.Formula:C20H22F3N5OPurezza:99.3% - >99.99%Colore e forma:SolidPeso molecolare:405.42Milciclib
CAS:Milciclib (PHA-848125) is a potent CDK2 inhibitor with a 45 nM IC50, selective over CDK1/2/4/5/7. In Phase 2 trials.Formula:C25H32N8OPurezza:99.28%Colore e forma:SolidPeso molecolare:460.57Ref: TM-T6081
1mg51,00€5mg106,00€10mg177,00€25mg376,00€50mg603,00€100mg905,00€200mg1.216,00€1mL*10mM (DMSO)110,00€STF-62247
CAS:<p>STF-62247 is TGN inhibitor with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively.</p>Formula:C15H13N3SPurezza:99.6% - 99.67%Colore e forma:SolidPeso molecolare:267.35Fenretinide
CAS:Fenretinide (4-HPR) is an orally-active synthetic retinoid derivative with potential antineoplastic and chemopreventive activities.Formula:C26H33NO2Purezza:98% - 99.68%Colore e forma:Yellow PowderPeso molecolare:391.55CD437
CAS:CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.Formula:C27H26O3Purezza:98.92% - 99.63%Colore e forma:SolidPeso molecolare:398.49FERULIC ACID METHYL ESTER
CAS:FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. FERULIC ACID METHYL ESTER has antioxidant activities.Formula:C11H12O4Purezza:99.66% - 99.95%Colore e forma:SolidPeso molecolare:208.21LRRK2-IN-1
CAS:LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.Formula:C31H38N8O3Purezza:98% - 98.82%Colore e forma:SolidPeso molecolare:570.69Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Formula:C9H6O4Purezza:97.47% - 99.8%Colore e forma:SolidPeso molecolare:178.14H-89 dihydrochloride
CAS:H-89 dihydrochloride (5-Isoquinolinesulfonamide) is a potent inhibitor of protein kinase A (PKA; IC50: 0.14 μM, Ki: 48 nM).Formula:C20H20BrN3O2S·2HClPurezza:98.22% - >99.99%Colore e forma:SolidPeso molecolare:519.28Ref: TM-T6250
5mg39,00€10mg58,00€25mg106,00€50mg202,00€100mg344,00€200mg512,00€500mg815,00€1mL*10mM (DMSO)52,00€PD98059
CAS:PD98059 is an MEK inhibitor that inhibits MEK1 and MEK2 (IC50=2/50 μM) and is non-ATP-competitive.Formula:C16H13NO3Purezza:98.63% - >99.99%Colore e forma:Yellow SolidPeso molecolare:267.28Ref: TM-T2623
5mg40,00€10mg52,00€25mg82,00€50mg106,00€100mg177,00€200mg264,00€500mg444,00€1mL*10mM (DMSO)58,00€ML327
CAS:ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).Formula:C19H18N4O4Purezza:98.47%Colore e forma:SolidPeso molecolare:366.37Ref: TM-T4252
1mg49,00€2mg65,00€5mg97,00€10mg144,00€25mg235,00€50mg376,00€100mg645,00€200mg898,00€1mL*10mM (DMSO)106,00€Sitagliptin phosphate
CAS:Sitagliptin phosphate (MK-0431 phosphate) is a dipeptidyl peptidase-4 (DPP4) inhibitor.Formula:C16H18F6N5O5PPurezza:99.72% - 99.91%Colore e forma:White SolidPeso molecolare:505.31KN-92 phosphate
CAS:KN-92 phosphate (KN92-H3PO4) is an inactive derivative of KN-93.Formula:C24H28ClN2O7PSPurezza:99.86%Colore e forma:SolidPeso molecolare:554.98Ref: TM-T4530
2mg35,00€5mg70,00€10mg105,00€25mg170,00€50mg259,00€100mg368,00€200mg522,00€1mL*10mM (DMSO)85,00€Wortmannin
CAS:Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible.Formula:C23H24O8Purezza:95.84% - 99.77%Colore e forma:White SolidPeso molecolare:428.43Ref: TM-T6283
1mg38,00€2mg49,00€5mg80,00€10mg119,00€25mg235,00€50mg406,00€100mg602,00€1mL*10mM (DMSO)88,00€Crizotinib hydrochloride
CAS:Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM)Formula:C21H23Cl3FN5OPurezza:98.73% - 98.87%Colore e forma:SolidPeso molecolare:486.8Ref: TM-T8399
5mg37,00€10mg52,00€25mg82,00€50mg99,00€100mg138,00€200mg171,00€500mg227,00€1mL*10mM (DMSO)59,00€Danusertib
CAS:<p>Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.</p>Formula:C26H30N6O3Purezza:97.88% - 98.79%Colore e forma:White PowderPeso molecolare:474.553-Methyladenine
CAS:3-Methyladenine (3-MA) is a PI3K inhibitor that selectively inhibits class IB PI3Kγ (IC50=60 μM) and class III VPS34 (IC50=25 μM).Formula:C6H7N5Purezza:98% - 99.51%Colore e forma:SolidPeso molecolare:149.15WYC-209
CAS:WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).Formula:C20H20N2O3SPurezza:99.77%Colore e forma:SolidPeso molecolare:368.45Salirasib
CAS:Salirasib: Competitive PPMTase inhibitor, blocks Ras methylation, potential cancer treatment, Ki=2.6 μM.Formula:C22H30O2SPurezza:99.45%Colore e forma:SolidPeso molecolare:358.54Ref: TM-T6163
5mg35,00€10mg52,00€25mg96,00€50mg159,00€100mg221,00€200mg364,00€500mg597,00€1mL*10mM (DMSO)59,00€MRT67307 HCl (1190378-57-4(free base))
MRT67307 is a kinase inhibitor of TBK1, MARK1-4, IKKε, and NUAK1 (IC50: 19, 27-52, 160, and 230 nM, respectively).Formula:C26H37ClN6O2Purezza:98.19%Colore e forma:SolidPeso molecolare:501.07Afatinib Dimaleate
CAS:Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Formula:C32H33ClFN5O11Purezza:98.11% - 99.87%Colore e forma:SolidPeso molecolare:718.08TA-02
CAS:<p>TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.</p>Formula:C20H13F2N3Purezza:99.35% - 99.79%Colore e forma:SolidPeso molecolare:333.33Sepantronium bromide
CAS:<p>Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.</p>Formula:C20H19BrN4O3Purezza:99.68% - 99.85%Colore e forma:SolidPeso molecolare:443.26LY294002
CAS:LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).Formula:C19H17NO3Purezza:98% - 99.96%Colore e forma:Pale Yellow SolidPeso molecolare:307.34PFI-1
CAS:PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.Formula:C16H17N3O4SPurezza:98.74% - 99.19%Colore e forma:SolidPeso molecolare:347.393'-Hydroxypterostilbene
CAS:3'-Hydroxypterostilbene suppresses colon cancer cell growth (COLO 205, HCT-116, HT-29) by triggering apoptosis and autophagy, affecting key pathways.Formula:C16H16O4Purezza:98.25% - 99.19%Colore e forma:SolidPeso molecolare:272.3BIIB021
CAS:BIIB021 (CNF2024) is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).Formula:C14H15ClN6OPurezza:98% - 99.82%Colore e forma:SolidPeso molecolare:318.76Sapanisertib
CAS:Sapanisertib (INK 128) is an oral raptor-mTOR and rictor-mTOR inhibitor with potential cancer-fighting properties.Formula:C15H15N7OPurezza:99.19% - >99.99%Colore e forma:SolidPeso molecolare:309.33Ref: TM-T1838
1mg40,00€2mg51,00€5mg85,00€10mg96,00€25mg160,00€50mg235,00€100mg350,00€500mg838,00€1mL*10mM (DMSO)88,00€Flavopiridol hydrochloride
CAS:Flavopiridol hydrochloride (MDL 107826A), an inhibitor of cyclin-dependent kinase, is a synthetic N-methylpiperidinyl chlorophenyl flavone compound.Formula:C21H21Cl2NO5Purezza:98.87% - 99.88%Colore e forma:SolidPeso molecolare:438.3Orthanilamide
CAS:Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.Formula:C6H8N2O2SPurezza:99.72% - 99.96%Colore e forma:White To Pale Cream Crystalline Powder Or CrystalsPeso molecolare:172.2Doramapimod HCl
CAS:Doramapimod HCl, a p38MAPK inhibitor in clinical trials for autoimmune diseases, has slow binding kinetics.Formula:C31H38ClN5O3Colore e forma:SolidPeso molecolare:564.13AGN 193109
CAS:AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ).Formula:C28H24O2Purezza:99.87% - 99.89%Colore e forma:SolidPeso molecolare:392.49Ref: TM-TQ0097
2mg90,00€5mg153,00€10mg235,00€25mg424,00€50mg655,00€100mg938,00€1mL*10mM (DMSO)Prezzo su richiestaMPP+ iodide
CAS:MPP+ iodide, a neurotoxin byproduct, mimics Parkinson's by killing substantia nigra neurons and affecting neuron transporters, inducing cell death.Formula:C12H12INPurezza:99.49% - 99.96%Colore e forma:SolidPeso molecolare:297.13GSK2578215A
CAS:GSK2578215A is a potent and selective LRRK2 kinase inhibitor.Formula:C24H18FN3O2Purezza:99.57% - 99.94%Colore e forma:SolidPeso molecolare:399.42Imatinib
CAS:Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kitFormula:C29H31N7OPurezza:99.42% - 99.94%Colore e forma:Off White PowderPeso molecolare:493.6Demethoxycurcumin
CAS:Demethoxycurcumin: antioxidant, anti-inflammatory, anti-proliferative, anti-acanthamoebic, enhances chemo for resistant cancers, inhibits cancer pathways.Formula:C20H18O5Purezza:94.54% - 99.86%Colore e forma:SolidPeso molecolare:338.35Ref: TM-T6S1683
5mg44,00€10mg55,00€25mg93,00€50mg158,00€100mg224,00€200mg330,00€1mL*10mM (DMSO)55,00€Cilofexor tromethamine
CAS:Cilofexor (GS-9674), a nonsteroidal FXR agonist, reduces cholestasis and liver damage in PSC, showing safety and efficacy in trials.Formula:C32H33Cl3N4O8Colore e forma:SolidPeso molecolare:707.99Aloperine
CAS:Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.Formula:C15H24N2Purezza:98% - 99.88%Colore e forma:Yellow Crystalline PowderPeso molecolare:232.36Arglabin
CAS:Arglabin ((+)-Arglabin) is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has anti-atherogenic and anticancer effects.Formula:C15H18O3Purezza:98.97% - 99.62%Colore e forma:SolidPeso molecolare:246.3Ref: TM-TQ0165
1mg88,00€2mgPrezzo su richiesta5mg240,00€10mg360,00€25mg518,00€50mg692,00€100mg1.035,00€200mg1.388,00€1mL*10mM (DMSO)310,00€Bilobalide
CAS:Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations.Formula:C15H18O8Purezza:98.81% - 99.92%Colore e forma:White SolidPeso molecolare:326.30Amsacrine gluconate
CAS:Amsacrine gluconate: an aminoacridine with anticancer properties, possibly works by intercalating DNA and inhibiting topoisomerase II.Formula:C27H31N3O10SColore e forma:SolidPeso molecolare:589.62Apocynin
CAS:Apocynin (NSC 2146) is a specific NADPH-oxidase inhibitor (IC50: 10 μM).Formula:C9H10O3Purezza:99.71% - 99.98%Colore e forma:Yellowish To Brown PowderPeso molecolare:166.17HA15
CAS:HA15 targets BiP/GRP78/HSPA5, showing anti-cancer effects on all tested melanoma cells, resistant or patient-derived.Formula:C23H22N4O3S2Purezza:99.77% - 99.86%Colore e forma:SolidPeso molecolare:466.58Ref: TM-T6855
1mg35,00€2mg48,00€5mg72,00€10mg96,00€25mg187,00€50mg283,00€100mg439,00€1mL*10mM (DMSO)74,00€ISRIB (trans-isomer)
CAS:ISRIB (trans-isomer) is a potent inhibitor of PERK that rescues protein translation and prevents SG formation in the presence of P-eIF2α. Cost effective and quality assured.Formula:C22H24Cl2N2O4Purezza:97.86% - 99.27%Colore e forma:SolidPeso molecolare:451.34Binimetinib
CAS:Binimetinib (ARRY-162) is a MEK1/2 inhibitor (IC50=12 nM) with selective and oral activity. Binimetinib has antitumor activity. Cost-effective and quality-assured.Formula:C17H15BrF2N4O3Purezza:98.03% - >99.99%Colore e forma:SolidPeso molecolare:441.23Reparixin
CAS:Reparixin inhibits CXCR1 (IC50=1 nM) strongly, CXCR2 weakly (IC50=100 nM), and it's a CXCL8 receptor blocker.Formula:C14H21NO3SPurezza:98% - 99.89%Colore e forma:SolidPeso molecolare:283.39Ref: TM-T4163
5mg48,00€10mg62,00€25mg120,00€50mg187,00€100mg301,00€200mg449,00€1mL*10mM (DMSO)111,00€Daurisoline
CAS:Daurisoline ((R,R)-Daurisoline) is a hERG inhibitor. Daurisoline is also an autophagy blocker.Formula:C37H42N2O6Purezza:98% - 99.96%Colore e forma:Light Yellow PowderPeso molecolare:610.74
