Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(993 prodotti)
- Recettore dell'adenosina(246 prodotti)
- Recettore adrenergico(3.004 prodotti)
- Recettore della bombesina(33 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(153 prodotti)
- CaSR(33 prodotti)
- Recettore dei cannabinoidi(212 prodotti)
- Recettore della dopamina(433 prodotti)
- Recettore dell'endotelina(79 prodotti)
- Recettore GNRH(77 prodotti)
- GPCR19(32 prodotti)
- GRK(32 prodotti)
- GTPase(22 prodotti)
- Recettore del glucagone(182 prodotti)
- Proteina Hedgehog/Smoothened(47 prodotti)
- Recettore dell'istamina(381 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(26 prodotti)
- Recettore OX(41 prodotti)
- Recettore degli oppioidi(310 prodotti)
- PAFR(12 prodotti)
- PKA(51 prodotti)
- Recettore S1P(18 prodotti)
- SGLT(31 prodotti)
- Recettore Sigma(46 prodotti)
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Trovati 5745 prodotti di "Proteina G/GPCR"
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Pasireotide (diaspartate)
CAS:Pasireotide diaspartate (SOM230) has high agonist activity at sst1/2/3/5, less at sst4; it's antiproliferative and proapoptotic.Formula:C66H80N12O17Colore e forma:SolidPeso molecolare:1313.41Efranarelaxin alfa
CAS:<p>Efranarelaxin alfa is an agonist of the relaxin receptor. It shows potential for research in cardiovascular diseases and tissue repair.</p>Colore e forma:Liquid3-Deoxyglucosone
CAS:3-Deoxyglucosone(3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with proteinFormula:C6H10O5Purezza:95%Colore e forma:SolidPeso molecolare:162.14[18F]-Labeled L-dopa precursor
CAS:[18F]-Labeled L-dopa precursor is a precursor for synthesis of 18F-labeled L-dopa[1].Formula:C35H36N2O7Colore e forma:SolidPeso molecolare:596.67Substance P(1-7) TFA
CAS:Substance P(1-7) TFA is a fragment of neuropeptide P (SP), with anti-harmful effects, used in neurological disease research.Formula:C43H66F3N13O12Purezza:98.23%Colore e forma:SolidPeso molecolare:1014.06Motilin, canine
CAS:<p>Motilin canine, a 22-amino acid peptide, functions as a robust gastrointestinal smooth muscle contraction agonist.</p>Formula:C120H194N36O34Purezza:98%Colore e forma:SolidPeso molecolare:2685.05Tocrifluor T1117
CAS:Fluorescent form of AM 251, CB1 receptor antagonistFormula:C56H53Cl2N7O5Purezza:98%Colore e forma:SolidPeso molecolare:974.97NI-203
<p>NI-203 is a monoclonal antibody inhibitor that targets amylin and shows potential for research in type 2 diabetes.</p>Colore e forma:Odour LiquidGIP/GLP-1 dual receptor agonist-1
CAS:Compound 4: GIP/GLP-1 agonist for metabolic/fatty liver disease research.Colore e forma:SolidMK-0493 HCl
CAS:MK-0493 is a novel, potent, and selective agonist for melanocortin receptor 4 (MC4R).Formula:C30H39Cl2F2N3O2Colore e forma:SolidPeso molecolare:582.55Melanostatin, frog TFA
Melanostatin, frog TFA is an α-MSH release inhibitor, a 36 amino acid peptide isolated from the frog brain.Purezza:99.23%Colore e forma:Odour SolidPEN (rat)
CAS:PEN (rat) is an Endogenous peptide GPR83 agonist. ProSAAS-derived neuropeptide.Formula:C102H169N27O33Purezza:98%Colore e forma:SolidPeso molecolare:2301.62Alosetron-d3
CAS:<p>Alosetron D3 (GR 68755 D3) is a deuterium-labeled Alosetron. Alosetron is an antagonist of 5HT3-receptor.</p>Formula:C17H18N4OPurezza:98%Colore e forma:SolidPeso molecolare:297.3715(S)-HpEPE
CAS:15(S)-HpEPE, a monohydroperoxy fatty acid, forms when 15-lipoxygenase acts on EPA, with expected biological activities akin to 15(S)-HpETE.Formula:C20H30O4Colore e forma:SolidPeso molecolare:334.456CB2R/FAAH modulator-3
CAS:<p>CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH.</p>Formula:C22H31NO2Purezza:99.81%Colore e forma:SoildPeso molecolare:341.49Ki16198
CAS:<p>Ki16198, a methyl ester derivative of Ki16425, blocks LPA1/3, weak on LPA2; inactive on LPA4/5/6. Ki values: 0.34 μM (LPA1), 0.93 μM (LPA3).</p>Formula:C24H25ClN2O5SPurezza:98.09%Colore e forma:SolidPeso molecolare:488.98Satavaptan
CAS:Satavaptan is a vasopressin V2 receptor antagonist. Satavaptan improves the control of ascites in cirrhosis.Formula:C33H45N3O8SColore e forma:SolidPeso molecolare:643.79A2A/A3 AR antagonist-1
A2A/A3 AR antagonist-1 is a dual fluorescent AR ligand with K i of 90 nM (hA2A) & 31.8 nM (hA3).Formula:C56H71N15O12S2Colore e forma:SolidPeso molecolare:1210.3913,14-dihydro Prostaglandin F2α
CAS:13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain.Formula:C20H36O5Colore e forma:SolidPeso molecolare:356.503L-796,778 acetate
<p>L-796,778 acetate is a slective somatostatin receptor agonist with IC50 of 24nM for sst3, for sst1, sst2, sst4 and sst5, IC50 is >1000nM.</p>Formula:C31H44N6O9Purezza:98%Colore e forma:SoildPeso molecolare:644.72Tryptamine hydrochloride
CAS:<p>Tryptamine hydrochloride is a monoamine alkaloid, metabolite of tryptophan and CNS active substance, agonist of 5-HT4 receptor, TAAR1, AHR.</p>Formula:C10H13ClN2Purezza:99.89%Colore e forma:SolidPeso molecolare:196.68A3AR modulator 1
MRS8054 is an oral A3 adenosine receptor positive allosteric modulator, enhancing Cl-IB-MECA-induced activity.Formula:C23H25IN4Colore e forma:SolidPeso molecolare:484.38[D-Trp34]-Neuropeptide Y
CAS:Potent NPY Y5 receptor agonist (pEC50 = 7.82); highly selective; induces hyperphagia, body weight gain; orally active.Formula:C196H289N55O56Purezza:98%Colore e forma:SolidPeso molecolare:4311.77GLP-1 receptor agonist 8
CAS:<p>GLP-1 receptor agonist 8, potent for diabetes and obesity research, may also study NAFLD.</p>Formula:C34H36ClFN6O4Colore e forma:SolidPeso molecolare:647.14[Des-Arg9]-Bradykinin acetate
CAS:[Des-Arg9]-Bradykinin acetate is a selective agonist of Bradykinin B1 receptor.Formula:C46H65N11O12Purezza:99.05%Colore e forma:SolidPeso molecolare:964.07Mosliciguat
CAS:Mosliciguat is a guanylate cyclase activator.Formula:C41H36ClF3N2O5Colore e forma:SolidPeso molecolare:729.19Latanoprost tris(triethylsilyl) ether
CAS:Latanoprosttris(triethylsilyl) ether is a precursor in the synthesis of Latanoprost, which serves as an agonist for the prostaglandin F2α (PGF2α) receptor, also known as the FP receptor.Formula:C44H82O5Si3Colore e forma:SolidPeso molecolare:775.38ARC 239 dihydrochloride
CAS:<p>ARC 239 dihydrochloride is a selective α2B adrenoceptor antagonist (pKD values are 8.8, 6.7 and 6.4 at α2B, α2A, and α2D receptors respectively).</p>Formula:C24H31Cl2N3O3Purezza:99.72%Colore e forma:SolidPeso molecolare:480.43Bucindolol Formate
Bucindolol is a β1-adrenergic blocker with sympathomimetic activity, used in heart failure research.Formula:C23H27N3O4Purezza:99.76% - 99.88%Colore e forma:SolidPeso molecolare:409.48AMTG-DA1
<p>AMTG-DA1 is a ligand for the gastrin-releasing peptide receptor (GRPR), and it can be utilized in cancer research.</p>Formula:C101H149IN22O25Colore e forma:SolidPeso molecolare:2197.0109Bradykinin (1-7)
CAS:Bradykinin (1-7), an amino-truncated peptide derived from Bradykinin, is a metabolite formed through enzymatic cleavage by endopeptidase.Formula:C35H52N10O9Purezza:98%Colore e forma:White Lyophilized PowderPeso molecolare:756.85BMS-604992 free base
CAS:<p>BMS-604992 (EX-1314), a selective GHSR agonist, binds strongly (ki=2.3 nM), is orally active, and increases rodent food intake.</p>Formula:C24H31N7O5Colore e forma:SolidPeso molecolare:497.556APP-FUBINACA
CAS:APP-FUBINACA is a cannabinoid receptor agonist, classified as a phenylalanine amide-based indazole-3-carboxamide derivative. It exhibits neurostimulatory effects.Formula:C24H21FN4O2Colore e forma:SolidPeso molecolare:416.45Luseogliflozin
CAS:Luseogliflozin inhibits SGLT2 for glucose uptake with 1.10 nM potency.Formula:C23H30O6SColore e forma:SolidPeso molecolare:434.55Tecastemizole
CAS:Tecastemizole (R 43512) is a selective antagonist of H1 receptor and a major metabolite of astemizole with anti-inflammatory effects.Formula:C19H21FN4Purezza:99.70%Colore e forma:SolidPeso molecolare:324.4MDL 29913
CAS:NK2 tachykinin receptor selective antagonist.Formula:C40H56N8O6Purezza:98%Colore e forma:SolidPeso molecolare:745Benzomalvin A
CAS:<p>Benzomalvin A is a filamentous fungal secondary metabolite.</p>Formula:C24H19N3O2Colore e forma:SolidPeso molecolare:381.43Bim 21009
CAS:Bim 21009 is an inhibitor of gonadorelin.Formula:C74H92ClN17O13Purezza:98%Colore e forma:SolidPeso molecolare:1463.08Adenosine receptor antagonist 1
CAS:A2aR-selective antagonist with IC50 of 0.29 nM; 14x more selective over A2bR.Formula:C22H15ClFN7OColore e forma:SolidPeso molecolare:447.86Vatinoxan
CAS:Vatinoxan is a peripheral α2 adrenoreceptor antagonist.Formula:C20H26N4O4SPurezza:98%Colore e forma:SolidPeso molecolare:418.51CCR4 antagonist 3
CAS:<p>Orally active CCR4 antagonist with piperidinyl-azetidine; IC50: 22 nM (calcium flux), 50 nM (CTX); antitumor effects.</p>Formula:C24H27Cl2N7OColore e forma:SolidPeso molecolare:500.43SC-53116
CAS:SC-53116 HCl can increase the production of serotonin in central nervous system tissues and is a psychoactive agent.Formula:C16H22ClN3O2Colore e forma:SolidPeso molecolare:323.82hA3AR agonist 2
hA3AR agonist 2 is a potent activator of A3AR, with a Ki value of 3.5 nM.Formula:C11H14ClN5O2SColore e forma:SolidPeso molecolare:315.78Isobutyryl-L-carnitine
CAS:<p>Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.</p>Formula:C11H21NO4Purezza:98%Colore e forma:SolidPeso molecolare:231.29FXR/TGR5 agonist 1
CAS:FXR/TGR5 agonist 1 acts as an agonist on both FXR and TGR5 receptors and is utilized for treating fatty liver disease.Formula:C31H32ClN3O3Colore e forma:SolidPeso molecolare:530.07GLP-1 (9-36) amide
CAS:<p>GLP-1 (9-36) amide is an antagonist at the human GLP-1 receptor.</p>Formula:C140H214N36O43Purezza:97%Colore e forma:SolidPeso molecolare:3089.41Bodilisant
CAS:Bodilisant: nanomolar-affinity hH3R ligand, derived from piperidine, with BODIPY fluorophore.Formula:C27H34BF2N3OColore e forma:SolidPeso molecolare:465.4HTL22562
CAS:HTL22562 is a calcitonin gene-related peptide (CGRP) receptor antagonist for acute treatment of migraine.Formula:C40H49N11O5Colore e forma:SolidPeso molecolare:763.904Pemvidutide TFA
Pemvidutide (TFA), a GLP-1R/GCGR dual agonist, effectively reduces body weight, liver fat, and serum lipid levels, and is utilized in research on non-alcoholicFormula:C182H275N39O54·xC2HF3O2Colore e forma:SolidPeso molecolare:3873.35 (free base)15-keto-17-phenyl trinor Prostaglandin F2α ethyl amide
CAS:Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which hasFormula:C25H35NO4Colore e forma:SolidPeso molecolare:413.558O-Desmethyl-N-deschlorobenzoyl Indomethacin
CAS:O-Desmethyl-N-deschlorobenzoyl indomethacin, a metabolite of indomethacin, reduces HL-60 cell viability and aids in synthesizing PGD2 receptor antagonists.Formula:C11H11NO3Colore e forma:SolidPeso molecolare:205.213Vicasinabin
CAS:Vicasinabin: potent CB2 agonist; researches chronic pain, atherosclerosis, bone mass, neuroinflammation.Formula:C15H22N10OColore e forma:SolidPeso molecolare:358.414-Bromo-2,5-DMMA
CAS:4-Bromo-2,5-DMMA (Compound 2) demonstrates affinity for the 5-HT2 binding site and has an ED50 of 0.82 mg/kg in rat discrimination experiments.Formula:C12H18BrNO2Colore e forma:SolidPeso molecolare:288.18Δ8-THC-C8
CAS:Δ8-THC-C8 is a semi-synthetic cannabinoid. It acts as an agonist for the cannabinoid receptor 1 (CB1) with an EC50 value of 13.8 nM.Formula:C24H36O2Colore e forma:SolidPeso molecolare:356.5425N-NBOMe hydrochloride
CAS:25N-NBOMe hydrochloride is a derivative of 2C-N and acts as an agonist for the 5-HT2A and 5-HT2C receptors, with Ki values of 0.144 nM and 1.06 nM, respectively. It has minimal effect on the release of preloaded neurotransmitters from recombinant dopamine, serotonin, and norepinephrine transporters.Formula:C18H23ClN2O5Colore e forma:SolidPeso molecolare:382.84Imnopitant dihydrochloride
CAS:Imnopitant dihydrochloride is a neurokinin NK1 receptor antagonist [1] .Formula:C28H30Cl2F6N4OColore e forma:SolidPeso molecolare:623.465-MeO-MET
CAS:5-MeO-MET (5-Methoxy-N-methyl-N-ethyltryptamine) is a compound belonging to the 5-methoxytryptamine class. It acts as an agonist for 5-HT1A and 5-HT2A receptors. In mice, 5-MeO-MET inhibits locomotion and has sedative effects.Formula:C14H20N2OColore e forma:SolidPeso molecolare:232.32Substance P (1-9)
CAS:Substance P (1-9), a nonapeptide, slows its own inactivation and stimulates neurons.Formula:C52H77N15O12Purezza:98%Colore e forma:SolidPeso molecolare:1104.26KwFwLL-NH2
CAS:KwFwLL-NH2 is a hexapeptide that serves as a ligand for the ghrelin receptor (ghrelin receptor). This compound acts as a specific inverse agonist for the ghrelin receptor, exhibiting moderate potency (EC50=45.6 nM).Formula:C49H66N10O6Colore e forma:SolidPeso molecolare:891.11Lys-γ3-MSH(human)
CAS:Pro-opiomelanocortin (POMC) derived peptide that stimulates lipolysisFormula:C128H193N45O39SPurezza:98%Colore e forma:SolidPeso molecolare:3018.25CCR4 antagonist 3 hydrochloride
CAS:<p>Orally active CCR4 antagonist 3 hydrochloride with potent selectivity, IC50s: 22/50 nM; has antitumor properties.</p>Formula:C24H27Cl2N7O·xHClColore e forma:SolidTHX-B
CAS:THX-B, a potent non-peptidic p75 NTR antagonist, aids in researching diabetic kidney disease and neurodegenerative and inflammatory disorders.Formula:C16H24N6O4Colore e forma:SolidPeso molecolare:364.4LTD4 antagonist 2
CAS:LTD4 antagonist 2 (compound 6) functions as a leukotriene D4 (LTD4) antagonist with an IC50 of 2.8 μM for the cysteinyl leukotriene 1 receptor (CysLT1R). Additionally, it acts as an agonist for the G protein-coupled bile acid receptor 1 (GPBAR1), making it applicable for research into colitis, metabolic syndrome, and other GPBAR1- and CysLT1R-related diseases.Formula:C17H13NO3Colore e forma:SolidPeso molecolare:279.29[D-p-Cl-Phe6,Leu17]-VIP
CAS:Selective vasoactive intestinal peptide (VIP) receptor antagonist (IC50 = 125.8 nM). Displays no activity on glucagon, secretin or GRF receptors.Formula:C148H239ClN44O42Purezza:98%Colore e forma:SolidPeso molecolare:3342.24Albiglutide fragment TFA
Albiglutide fragment (GLP-1 (7-36) analog) TFA represents a biologically active segment of Albiglutide, resistant to DPP-4 degradation due to its structure as aFormula:C148H224N40O45·xC2HF3O2Colore e forma:SolidBIBP3226
CAS:<p>BIBP3226 is a potent and selective antagonist for the Neuropeptide Y receptor Y1 and the neuropeptide FF receptor.</p>Formula:C27H31N5O3Colore e forma:SolidPeso molecolare:473.57Eloralintide
CAS:Eloralintide (LY 3841136) is an AMYR agonist, anticipated for research in type 2 diabetes and obesity.Formula:C201H319N49O65S2Colore e forma:SolidPeso molecolare:4526.1Azaline
CAS:Azaline is a gonadorelin antagonist.Formula:C74H106ClN23O12Purezza:98%Colore e forma:SolidPeso molecolare:1545.26LHRH, Ala(6)-
CAS:LHRH, Ala(6)- is a synthetic luteinizing hormone-releasing hormone agonist agent.Formula:C56H77N17O13Colore e forma:SolidPeso molecolare:1196.32ADTN
CAS:ADTN is an agonist of the dopamine receptor.Formula:C10H13NO2Purezza:98%Colore e forma:SolidPeso molecolare:179.22Acrinor
CAS:<p>Acrinor is a adrenergic beta receptor agonist.</p>Formula:C35H46Cl2N10O8Purezza:98%Colore e forma:SolidPeso molecolare:805.72AC-178335
CAS:AC-178335: SRIF antagonist, Ki=172 nM, inhibits SRIF's adenylate cyclase effects (IC50=5.1 µM), triggers GH release in rats.Formula:C49H63N13O7Colore e forma:SolidPeso molecolare:946.11Denrakibart
<p>Denrakibart is a humanized IgG2κ antibody targeting CCL17, with HumanIgG2kappa, Isotype Control serving as the corresponding isotype control.</p>Colore e forma:Odour LiquidPSB-22269
PSB-22269 is identified as a GPR17 antagonist with a Ki value of 8.91 nM. It exhibits significant inhibitory effects in cAMP and G protein activation assays. Molecular docking studies indicate that the binding site of PSB-22269 includes positively charged arginine residues and a hydrophobic pocket. PSB-22269 promotes myelin regeneration strategies, offering potential for multiple sclerosis research.Formula:C26H21NO6Colore e forma:SolidPeso molecolare:443.45Imelciment
CAS:<p>Imelciment (REGN-9035) is a humanised monoclonal antibody targeting NPR1, which can be used for research into heart failure.</p>Purezza:95%Colore e forma:SoildPoly-D-lysine hydrobromide (MW 150000-300000)
Poly-D-lysine hydrobromide (MW 150000-300000) enhances neural cell adhesion in culture and acts as a calcium-sensing receptor agonist peptide in research.Colore e forma:Odour SolidAnti-TSHR Antibody (M22)
Anti-TSHR Antibody (M22) is a humanized IgG1 monoclonal antibody targeting the thyroid-stimulating hormone receptor (TSHR). This antibody is capable of inhibiting the interaction between TSH and TSHR.Colore e forma:Odour LiquidRS 56812
CAS:RS 56812 is a 5-HT3 receptor antagonist and agonist used in the study of cognitive disorders.Formula:C18H21N3O2Purezza:99.38%Colore e forma:SoildPeso molecolare:311.38Guanylin TFA (mouse,rat)
<p>Guanylin (mouse, rat) TFA is a peptide composed of 15 amino acids and acts as an activator of intestinal guanylate cyclase. This compound is utilized in research related to diarrhea.</p>Formula:C60H90N16O22S4·xC2HF3O2Colore e forma:SolidPeso molecolare:1515.71 (free base)β-CGRP (mouse)
<p>β-CGRP (mouse), a calcitonin gene-related peptide, induces vasodilation and is applicable in research areas including cardiovascular, pro-inflammatory, migraine, and metabolic studies.</p>Formula:C165H265N49O55S2Colore e forma:SolidPeso molecolare:3879.29Vazegepant
CAS:<p>Vazegepant is an intranasal CGRP receptor antagonist utilized for conducting acute migraine research.</p>Formula:C36H46N8O3Purezza:98.61%Colore e forma:SolidPeso molecolare:638.80Adenosine receptor agonist 1
<p>Compound 6m, an A3 adenosine receptor (AR) partial agonist, exhibits a K i value of 6.7 nM as an adenosine receptor agonist.</p>Formula:C12H14ClN5O2SeColore e forma:SolidPeso molecolare:374.68Detomidine carboxylic acid
CAS:Detomidine carboxylic acid, a urine metabolite of detomidine, is a synthetic α2-agonist, animal analgesic, with cardiac, respiratory, and diuretic effects.Formula:C12H12N2O2Purezza:98%Colore e forma:SolidPeso molecolare:216.24Pobilukast
CAS:Pobilukast (SKF 104353) is a cysteinyl leukotriene receptor antagonist that can be used to study limiting myocardial injury in MI/R rats.Formula:C26H34O5SPurezza:99.65% - 99.84%Colore e forma:SolidPeso molecolare:458.61KB-5492 FA
KB-5492 FA is a selective sigma receptor inhibitor with antiulcerogenic effects.CAS 번호128-52-56-8Formula:C24H32N2O8Purezza:98.12%Colore e forma:SolidPeso molecolare:476.52Linzagolix choline
CAS:Linzagolix choline is a GnRH antagonist. It can be used to study pain associated with uterine fibroids and endometriosis.Formula:C27H28F3N3O8SPurezza:99.64%Colore e forma:SolidPeso molecolare:611.59Tebufelone
CAS:<p>Tebufelone is a potent NSAID, inhibits CO, has anti-inflammatory and analgesic properties, and blocks lipoxygenase products (IC50 ~20-22 microM).</p>Formula:C20H28O2Purezza:99.32%Colore e forma:SolidPeso molecolare:300.44Galcanezumab
CAS:Galcanezumab: humanized IgG4 antibody that targets CGRP for migraine and cluster headache prevention/treatment.Purezza:> 95%Colore e forma:LiquidPeso molecolare:144.08 kDaTirzepatide
CAS:Tirzepatide (LY-3298176) is a dual glucose-dependent polypeptide (GIP) (EC50=0.042 nM) and glucagon-like peptide-1 (GLP-1) (EC50=0.086 nM) receptor agonist.Formula:C225H348N48O68Purezza:99.52% - 99.99%Colore e forma:SolidPeso molecolare:4813.45Brexpiprazole S-oxide
CAS:Brexpiprazole S-oxide is the main metabolite of Brexpiprazole, a human 5-HT1A and dopamine receptor partial agonist (Ki: 0.12, 0.3 nM).Formula:C25H27N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:449.57TAK-448 acetate
CAS:TAK-448 acetate (MVT-602 acetate) is a KISS1R agonist, a synthetic peptide similar to kisspeptin.Formula:C60H84N16O16Purezza:99.88%Colore e forma:SolidPeso molecolare:1285.41Xanthine amine congener dihydrochloride
CAS:<p>XAC dihydrochloride is an Adenosine A1 and A2 receptor antagonist with IC50s of 1.8 nM and 114 nM, also a mouse convulsant.</p>Formula:C21H30Cl2N6O4Colore e forma:SolidPeso molecolare:501.41Dulaglutide
CAS:<p>Dulaglutide (LY2189265) is a GLP-1 receptor agonist for studying type 2 diabetes mellitus (T2DM).</p>Colore e forma:SolidP2Y6R antagonist 1
P2Y6R antagonist 1 (compound 5ab) is a selective, orally active antagonist of P2Y6R, featuring an IC50 value of 19.6 nM. This compound also exhibits anti-inflammatory properties.Colore e forma:Odour SolidINCB 3284 dimesylate
CAS:INCB 3284 dimesylate: oral CCR2 antagonist, blocks MCP-1/hCCR2 binding (IC50: 3.7 nM), potential in acute liver failure research.Formula:C28H39F3N4O10S2Purezza:98%Colore e forma:SolidPeso molecolare:712.76PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)
PACAP (6-27) is an antagonist for PACAP receptors with varying IC50s; blocks cAMP in neuroblastoma and breast cancer cells.Colore e forma:LiquidEsprolol
CAS:<p>Esprolol (ACC-9369 free base) is a novel beta-adrenergic antagonist used to study exertional angina.</p>Formula:C17H27NO4Purezza:71.58% - 99.16%Colore e forma:SoildPeso molecolare:309.4Nadolol
CAS:<p>Nadolol is a non-selective beta-adrenergic antagonist with antihypertensive and antiarrhythmic activities.</p>Formula:C17H27NO4Purezza:99.87% - 99.92%Colore e forma:White To Off-White Crystalline Powder SolidPeso molecolare:309.40Fabesetron
CAS:<p>Fabesetron (FK1052): oral dual antagonist for 5-HT3/5-HT4 receptors. Aids in managing acute and delayed chemo-induced emesis.</p>Formula:C18H19N3OColore e forma:SolidPeso molecolare:293.37ABT 724 trihydrochloride
CAS:<p>ABT-724 trihydrochloride: selective D4 agonist; EC50=12.4nM(human),14.3nM(rat),23.2nM(ferret); for erectile dysfunction research.</p>Formula:C17H22Cl3N5Purezza:99.91%Colore e forma:SolidPeso molecolare:402.75GR231118
CAS:<p>Potent NPY Y1 antagonist & Y4 agonist; inhibits rat appetite; binds to NPFF receptors (Ki: 43-73 nM).</p>Formula:C110H170N34O24Purezza:98%Colore e forma:Lyophilized PowderPeso molecolare:2352.77Stressin I TFA
<p>Stressin I (Cyclo(31-34)[DPhe12, Nle21, 38, Glu31, Lys34]Ac-hCRF(4-41)) TFA, with a K i of 1.7 nM, is a potent and selective agonist of the CRF1 receptor.</p>Purezza:98%Colore e forma:Odour SolidIRL-1038 acetate
<p>IRL-1038 acetate is a potent ETB endothelin receptor antagonist.</p>Formula:C70H96N14O17S2Purezza:97.51%Colore e forma:SoildPeso molecolare:1469.73A3AR agonist 2
<p>Compound 19, a selective A3 Adenosine Receptor (A3AR) agonist (K i : 22.1 nM), effectively stimulates β-arrestin2 recruitment with an EC 50 value of 4.36 nM.</p>Formula:C34H34N6O6Purezza:98%Colore e forma:SolidPeso molecolare:622.67Guanylin (mouse, rat)
CAS:<p>Guanylin (mouse, rat), a peptide consisting of 15 amino acids, acts as an activator of intestinal guanylate cyclase and is utilized in diarrhea research [1].</p>Formula:C60H90N16O22S4Purezza:98%Colore e forma:SolidPeso molecolare:1515.71NF546 hydrate
<p>NF546 (hydrate), a selective non-nucleotide P2Y11 agonist, exhibits a pEC50 value of 6.27 and induces interleukin-8 secretion from human monocyte-derived</p>Formula:C47H44N6Na4O17P4·5H2OPurezza:98%Colore e forma:SolidPeso molecolare:1424.01Urocortin III, mouse
CAS:Mouse UcnIII, linked to stress behaviors, mainly occurs in the brain and rises in the hypothalamus post-restraint.Formula:C186H312N52O52S2Purezza:98%Colore e forma:SolidPeso molecolare:4172.97D3R ligand 1
<p>D3R Ligand 1 (compound 23b) is a potent, selective antagonist of the dopamine D3 receptor (Ki=66 nM), incorporating a THPB template.</p>Formula:C27H37NO5Purezza:98%Colore e forma:SolidPeso molecolare:455.59PSB 0777 ammonium hydrate
<p>PSB 0777 ammonium hydrate is a potent and selective adenosine A2A receptor full agonist, exhibiting K i values of 44.4 nM for rat A2A receptors and 360 nM for</p>Formula:C18H20N5O7S2·NH4·75H2OPurezza:98%Colore e forma:SolidPeso molecolare:532.09Dp[Tyr(methyl)2,Arg8]-Vasopressin
CAS:<p>Dp[Tyr(Me)2,Arg8]-Vasopressin is a non-selective antagonist of the peptide arginine vasopressin V1b receptor [1].</p>Formula:C49H70N14O12S2Purezza:98%Colore e forma:SolidPeso molecolare:1111.34-Thiouridine 5′-triphosphate disodium
CAS:<p>4-Thiouridine 5′-triphosphate (4-Thio-UTP) tetrasodium functions as a potent agonist at P2Y 2 and P2Y 4 receptors, with half-maximal effective concentrations (</p>Formula:C9H11N2Na2O14P3SPurezza:98%Colore e forma:SolidPeso molecolare:546.195-HT6R antagonist 1
<p>Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stability</p>Formula:C17H22F2N6OPurezza:98%Colore e forma:SolidPeso molecolare:364.39CB2 PET Radioligand 1
CB2 PET Radioligand 1 (compound [18F]9) is a positron emission tomography (PET) radioligand with high affinity for the human cannabinoid receptor 2 (hCB2, Ki=7.Formula:C20H19F3N4OPurezza:98%Colore e forma:SolidPeso molecolare:388.39BQ-3020 ammonium
BQ-3020 ammonium, a selective endothelin receptor (ET B receptor) agonist, demonstrates inhibition of [125 I] ET-1 binding to ET B receptors with an IC50 of 0.2Formula:C96H140N20O25S·xNH3Purezza:98%Colore e forma:SolidPeso molecolare:2006.32 (free base)TCMCB07 TFA
TCMCB07 TFA is a cyclic nonapeptide and an orally active, brain-penetrating antagonist of the melanocortin receptor 4 (MC4R), playing a significant role inFormula:C63H87N15O11·xC2HF3O2Purezza:98%Colore e forma:SolidPeso molecolare:1230.46 (free base)PG106
CAS:Selective hMC3 receptor antagonist (IC50 = 210 nM). Exhibits no activity at hMC4 receptors and hMC5 receptors.Formula:C51H69N13O9Purezza:98%Colore e forma:SolidPeso molecolare:1008.19Invopressin
CAS:<p>Invopressin (Compound 42), a vasopressin V1A receptor partial agonist (EC50: 1.0 nM), is utilized in research related to cirrhosis conditions such as bacterial</p>Formula:C110H161N31O27S2Purezza:98%Colore e forma:SolidPeso molecolare:2413.78Clozapine N-oxide dihydrochloride
CAS:Clozapine N-oxide dihydrochloride is a derivative of Clozapine and an agonist of DREADDs.Formula:C18H21Cl3N4OPurezza:98.11%Colore e forma:SolidPeso molecolare:415.74(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin
CAS:<p>(d(CH2)5[Tyr(Me)2, Dab5]AVP), a vasopressin V1a receptor-specific antagonist, demonstrates a pA2 value of 6.71 [1].</p>Formula:C52H76N14O11S2Purezza:98%Colore e forma:SolidPeso molecolare:1137.38PSB-1114 triethylamine
<p>PSB-1114 triethylamine is a potent, enzymatically stable, P2Y2 receptor agonist with a 134 nM EC50, exhibiting greater than 50-fold selectivity over P2Y4 (EC50</p>Formula:C10H15F2N3O13P3S·xC6H15NPurezza:98%Colore e forma:Solidα-CGRP (mouse, rat) TFA
<p>α-CGRP (mouse, rat) TFA, a neuropeptide belonging to the calcitonin gene-related peptide (CGRP) family, is predominantly located at neuromuscular junctions and</p>Formula:C162H262N50O52S2·C2HF3O2Purezza:98%Colore e forma:SolidEmoghrelin
CAS:<p>Emoghrelin, extracted from Heshouwu (Polygonum multiflorum), promotes the secretion of growth hormone by activating the ghrelin receptor [1].</p>Formula:C24H22O13Purezza:98%Colore e forma:SolidPeso molecolare:518.42FFN246
CAS:FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation andFormula:C15H13FN2OPurezza:98%Colore e forma:SolidPeso molecolare:256.27Oxmetidine FA
<p>Oxmetidine FA is an orally available specific histamine H2 receptor antagonist with antiulcerogenic properties.</p>Formula:C20H23N5O5SPurezza:97.34%Colore e forma:SoildPeso molecolare:445.49AdTx1
<p>Selective non-competitive α1A adrenoceptor antagonist with Ki of 0.35 nM; inactive on other GPCRs; affects phenylephrine actions.</p>Formula:C310H481N87O100S8Purezza:98%Colore e forma:SolidPeso molecolare:7283.22Pafenolol
CAS:Pafenolol is a P-glycoprotein modulator with a Ki value of 5.5 µM. pafenolol is an orally available and selective beta-adrenergic receptor antagonist.Formula:C18H31N3O3Purezza:98.33%Colore e forma:SolidPeso molecolare:337.46TGR5 agonist 4
<p>TGR5 agonist 4 (compound 19), a derivative of cholic acid, selectively activates the TGR5 receptor with an effective concentration (EC50) of 4 μM [1].</p>Formula:C24H38F2O5Colore e forma:SolidPeso molecolare:444.55S1R agonist 2
CAS:<p>S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.</p>Formula:C21H27NOPurezza:98.85%Colore e forma:SolidPeso molecolare:309.45O-Desmethyl Mebeverine alcohol
CAS:Mebeverine metabolite O-desmethyl alcohol inhibits α1 receptors, relaxing the gut.Formula:C15H25NO2Purezza:98%Colore e forma:SolidPeso molecolare:251.36CAY10509
CAS:<p>CAY10509 is a PGF2α analogue and acts as an FP receptor inhibitor with an IC50 of 30 nM. It shows potential for use in studying the physiological regulatory mechanisms related to prostaglandins.</p>Formula:C23H35FO5SColore e forma:SolidPeso molecolare:442.58PACAP (1-38), human, ovine, rat TFA
PACAP (1-38), neuropeptide from bovine brain, surpasses VIP in adenylate cyclase activation (EC50=7 nM), alters peptide release, affects gastrin and motility.Formula:C203H331N63O53S·C2HF3O2Purezza:98%Colore e forma:SolidPeso molecolare:4648.28K41498
CAS:Potent CRF2α/β antagonist; Ki: 0.66/0.62 nM, weak for CRF1 (425 nM). Blocks sauvagine in hCRF2 cells and urocortin hypotension in rats.Formula:C162H276N48O46Purezza:98%Colore e forma:SolidPeso molecolare:3632.266-Fluoro-N,N-diethyltryptamine
CAS:6-Fluoro-N,N-diethyltryptamine (6-F-DET) exhibits affinity for the 5-HT2A receptor.Formula:C14H19FN2Colore e forma:SolidPeso molecolare:234.31Neuropeptide S(Mouse)
CAS:<p>Endogenous NPSR agonist, EC50 = 3 nM. Boosts Ca2+ levels, activity, wakefulness, reduces anxiety in mice.</p>Formula:C93H156N34O27Purezza:98%Colore e forma:SolidPeso molecolare:2182.47Casopitant
CAS:Casopitant (GW679769) is an orally active neurokinin-1 (NK1) receptor antagonist, researched for its potential use in managing chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV).Formula:C30H35F7N4O2Colore e forma:SolidPeso molecolare:616.61BAY-6672
CAS:BAY-6672 is, a selective,oral, highly potent human prostaglandin F (FP) receptor antagonist, exerts antifibrotic effects by inhibiting PGF₂α activity.Formula:C26H27BrClN3O3Purezza:99.51%Colore e forma:SolidPeso molecolare:544.87PAF C-18
CAS:PAF C-18 is a natural phospholipid molecule belonging to the platelet-activating factor (PAF) family,, involved in hemostasis and thrombosis by binding to PAFR.Formula:C28H58NO7PPurezza:>99.99%Colore e forma:SolidPeso molecolare:551.74Methamnetamine hydrochloride
CAS:Methamnetamine (PAL-1046) hydrochloride is a psychoactive substance derived from phenethylamine, known to cause excessive serotonin release.Formula:C14H18ClNColore e forma:SolidPeso molecolare:235.75δ8-THC acetate
CAS:Delta8-THC acetate (Delta8-tetrahydrocannabinol) is a psychoactive cannabinoid that binds to the cannabinoid receptor 1 (CB1 receptor) and exhibits anti-nausea, appetite-stimulating, and anti-inflammatory effects. It may also offer neuroprotective benefits and has potential applications in research on anxiety and depression.Formula:C23H32O3Colore e forma:SolidPeso molecolare:356.5Sibenadet hydrochloride
CAS:<p>Sibenadet, a D2/beta2-agonist, is potential useful for the treatment of symptoms of chronic obstructive pulmonary disease.</p>Formula:C22H29ClN2O5S2Colore e forma:SolidPeso molecolare:501.06SBI-810
CAS:SBI-810 is a functional selective β-arrestin-biased allosteric modulator of the neurotensin receptor 1 (NTSR1). In the presence of the endogenous ligand neurotensin (NT), SBI-810 regulates NTSR1 signaling through a G protein-specific mechanism. It fully antagonizes NT-induced Gq activation and partially antagonizes NT-induced Gi1 activation, allowing NTSR1 to activate GoA and G12.Formula:C27H34N4O2Colore e forma:SolidPeso molecolare:446.59CB2 receptor agonist 9
CAS:CB2 receptor agonist 9 (Compound 33) is an orally active agonist of cannabinoid receptor 2 (CB2 receptor) with an EC50 of 16.2 nM. It inhibits the expression of TNF-α, IL-1β, and IL-6, demonstrating anti-inflammatory activity in a DSS-induced acute colitis model in mice.Formula:C16H23N3O2SColore e forma:SolidPeso molecolare:321.44Meluadrine tartrate
CAS:<p>Meluadrine tartrate is an endogenous metabolite.</p>Formula:C16H24ClNO8Purezza:98%Colore e forma:SolidPeso molecolare:393.82Seglitide
CAS:<p>Peptide agonist targets sst2/sst5 receptors. IC50/Kd: sst1 >1000, sst2 = 0.2-1.5, sst3 = 27-36, sst4 >127, sst5 = 0.06-23 nM.</p>Formula:C44H56N8O7Purezza:98%Colore e forma:SolidPeso molecolare:808.98JMV 449
CAS:<p>Potent neurotensin agonist; IC50=0.15 nM, EC50=1.9 nM. Causes hypothermia, neuroprotection, analgesia in mice.</p>Formula:C38H66N8O7Purezza:98%Colore e forma:SolidPeso molecolare:746.96QWF acetate
<p>QWF acetate is a Substance P antagonist peptide that specifically inhibits the binding to its receptor, NK1, and inhibits the activation of MRGPRX2.</p>Formula:C40H47N5O10Purezza:96.65%Colore e forma:SolidPeso molecolare:757.84Pasireotide L-aspartate salt
CAS:Pasireotide L-aspartate, a stable cyclohexapeptide, mimics somatostatin with high affinity for sst1/2/3/4/5 receptors (pKi=8.2/9.0/9.1/<7.0/9.9).Formula:C62H73N11O13Purezza:98%Colore e forma:SolidPeso molecolare:1180.33Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate
CAS:Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate is an NPR-A agonist and ANP hormone. Carperitide increases cGMP levels and reduces the heart's workload.Formula:C129H207N45O41S3Purezza:99.78%Colore e forma:SoildPeso molecolare:3140.5[Sar9] Substance P
CAS:<p>[Sar9]-Substance P is one of NK-1 receptor agonist. The action of SP on progesterone metabolism was mimicked by the rNK1-specific agonist [Sar-9,Met(O2)11]-SP.</p>Formula:C64H100N18O13SPurezza:98%Colore e forma:SolidPeso molecolare:1361.66Surfagon
CAS:Surfagon is an effective LHRH agonist.Formula:C56H78N16O12Purezza:98%Colore e forma:SolidPeso molecolare:1167.34Pasireotide pamoate
CAS:Pasireotide pamoate is a stable cyclohexapeptide somatostatin mimic. Pasireotide pamoate exhibits antisecretory, antiproliferative, and proapoptotic activity.Formula:C81H82N10O15Purezza:98%Colore e forma:SolidPeso molecolare:1435.58L-796,778
CAS:<p>L-796,778 is an SST3 agonist and a selective ligand of SST3, which can increase the level of cAMP in the body.</p>Formula:C29H40N6O7Purezza:96.20%Colore e forma:SolidPeso molecolare:584.66BMS 193885
CAS:BMS 193885 is a selective and competitive neuropeptide Y(1) receptor antagonist with affinity of 3.3 nM.Formula:C36H48N4O9Purezza:98%Colore e forma:SolidPeso molecolare:680.79Fenoldopam
CAS:Fenoldopam is a selective D1-like dopamine receptor partial agonist (EC50 = 57 nM).Formula:C16H16ClNO3Purezza:98%Colore e forma:SolidPeso molecolare:305.76(R)-(+)-Atenolol
CAS:<p>(R)-(+)-Atenolol ((R)-Atenolol) is a cardioselective beta-1 adrenergic blocker, which properties are similar to propranolol, but without a negative inotropic effect.</p>Formula:C14H22N2O3Purezza:98.72%Colore e forma:SolidPeso molecolare:266.34(±)5(6)-EET
CAS:5(6)-EET is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.Formula:C20H32O3Colore e forma:SolidPeso molecolare:320.473Leukotriene B4 Ethanolamide
CAS:<p>LTB4 binds to BLT1 (high affinity) and BLT2. LTB4-EA, a metabolite, is a stronger BLT1 antagonist, suggesting anti-inflammatory properties.</p>Formula:C22H37NO4Colore e forma:SolidPeso molecolare:379.541RC-3095 TFA
CAS:<p>RC-3095 TFA (RC-3095 (TFA)) is a bombesin/gastrin-releasing peptide (BN/GRP) antagonist with potential anticancer activity.</p>Formula:C58H80F3N15O11Purezza:98%Colore e forma:SolidPeso molecolare:1220.34Dipentylone hydrochloride
CAS:Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.Formula:C14H20ClNO3Purezza:99.94%Colore e forma:SolidPeso molecolare:285.77β-CGRP, human
CAS:<p>β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascular</p>Formula:C162H267N51O48S3Purezza:98%Colore e forma:SolidPeso molecolare:3793.41Galantide acetate
Galantide acetate, a non-specific galanin receptor antagonist, is a peptide consisting of fragments of galanin and substance P.Formula:C106H155N25O28SPurezza:97.8% - 97.91%Colore e forma:SolidPeso molecolare:2259.58Amylin (8-37), rat
CAS:Amylin (8-37), rat, an analog of IAPP, blocks insulin's effects on muscle glucose uptake and glycogen storage.Formula:C140H227N43O43Purezza:98%Colore e forma:SolidPeso molecolare:3200.61A71378
CAS:A71378 is a high potency, selectivity CCK-A receptors agonist.Formula:C48H62N8O13SPurezza:98%Colore e forma:SolidPeso molecolare:991.12CAP-100
<p>CAP-100 is a monoclonal antibody targeting CCR7. It neutralizes the ligand binding site and signaling of CCR7. This compound effectively inhibits migration, extravasation, homing, and survival in chronic lymphocytic leukemia (CLL) samples induced by CCR7. CAP-100 can mediate potent tumor cell killing through host immune mechanisms and exhibits favorable toxicity profiles in related hematopoietic cell subsets. It is involved in research on antitumor activity and diseases like chronic lymphocytic leukemia (CLL).</p>Colore e forma:Odour LiquidNF157
CAS:<p>NF157, a selective P2Y11 antagonist with pKi 7.35, lowers MMP-3/MMP-13, aiding OA treatment; IC50s: P2Y11 463 nM, P2Y1 1811 μM, P2Y2 170 μM.</p>Formula:C49H28F2N6Na6O23S6Purezza:98%Colore e forma:SolidPeso molecolare:1437.1Setmelanotide
CAS:Setmelanotide (BIM-22493) is a selective agonist of melanocortin 4 receptor (MC4R)(human and rat MC4R with EC50s of 0.27 nM and 0.28 nM, respectively).Formula:C49H68N18O9S2Purezza:99.93%Colore e forma:SolidPeso molecolare:1117.31Bombinakinin M
CAS:Potent, selective bradykinin receptor agonist 50x stronger than bradykinin, contracts guinea pig ileum muscle at EC50 4.0 nM.Formula:C100H159N31O24Purezza:98%Colore e forma:SolidPeso molecolare:2179.55ANXA3 degrader 1
ANXA3 degrader 1 (Compound 18a5) is a highly selective ANXA3 degrader with activity against cancer cells. It demonstrates significant inhibitory effects in a triple-negative breast cancer (TNBC) tumor xenograft model, with a tumor growth inhibition (TGI) rate of 96%.Formula:C30H32N6O2S2Colore e forma:SolidPeso molecolare:572.74HAEGTFTSD
CAS:<p>HAEGTFTSD is GLP-1's initial segment; GLP-1 (7-36) amide, tied to food intake, stems from preproglucagon in L-cells.</p>Formula:C40H57N11O17Purezza:98%Colore e forma:SolidPeso molecolare:963.94Prostaglandin H1
CAS:Prostaglandin H1 is the cyclooxygenase metabolite of DGLA, a CRTh2 agonist and a precursor of a family of 1 anti-inflammatory prostaglandins.Formula:C20H34O5Colore e forma:SolidPeso molecolare:354.487CGRP 8-37 (rat)
CAS:CGRP 8-37 (rat) is a CGRP receptor antagonist, a CGRP fragment with potential anti-injury effects that induces arterial relaxation.Formula:C138H224N42O41Purezza:99.28%Colore e forma:SolidPeso molecolare:3127.5117-phenyl trinor Prostaglandin E2 ethyl amide
CAS:17-phenyl trinor PGE2 ethyl amide, an EP1/EP3 agonist (Ki: 14-54 nM), enhances lipid solubility and tissue uptake, is a potent antifertility agent.Formula:C25H35NO4Colore e forma:SolidPeso molecolare:413.55[D-Trp34]-Neuropeptide Y Acetate
<p>[D-Trp34]-Neuropeptide Y Acetate is a potent Y5 receptor agonist that increases rat food intake; less potent at Y1, Y2, Y4, Y6.</p>Formula:C198H293N55O58Purezza:99.73%Colore e forma:SoildPeso molecolare:4371.78CB2 receptor agonist 2
CAS:<p>CB2 receptor agonist 2 (ZINC72105556): potent, Ki=8.5 nM, high selectivity for CB2.</p>Formula:C30H36N2O4Purezza:99.75%Colore e forma:SolidPeso molecolare:488.62Galantide
CAS:Galantide is a reversible and non-specific antagonist of galanin receptor.Formula:C104H151N25O26SPurezza:98%Colore e forma:White Lyophilised SolidPeso molecolare:2199.53Phenylethanolamine A
CAS:Phenylethanolamine A is a β-adrenergic agonist and a byproduct of the Ractopamine synthesis process.Formula:C19H24N2O4Colore e forma:SolidPeso molecolare:344.40[D-Phe12,Leu14]-Bombesin
CAS:<p>Bombesin receptor blocker; stops binding in rat brain (IC50=2 μM), hinders amylase release (IC50=4 μM), reduces appetite suppression in vivo.</p>Formula:C77H113F3N22O20Purezza:98%Colore e forma:SolidPeso molecolare:1724.9HAEGT
CAS:<p>HAEGT is the first N-terminal 1-5 residues of GLP-1 peptide.</p>Formula:C20H31N7O9Purezza:98%Colore e forma:SolidPeso molecolare:513.5MAO-B-IN-3
<p>MAO-B-IN-3 is a reversible, selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and demonstrates affinity for the 5-HT6 receptor with a Ki</p>Formula:C24H25N3O2Purezza:98%Colore e forma:SolidPeso molecolare:387.47Neuropeptide Y (13-36), amide, human
CAS:Neuropeptide Y (13-36), amide, human is a neuropeptide Y receptor agonist.Formula:C134H207N41O36SPurezza:98%Colore e forma:SolidPeso molecolare:3000.4MRS2500 tetraammonium
CAS:<p>Highly potent and selective antagonist of the platelet P2Y1 receptor</p>Formula:C13H21IN6O8P2Purezza:98%Colore e forma:SolidPeso molecolare:578.19Cortistatin 14, human, rat
CAS:<p>Cortistatin 14: a neuropeptide similar to somatostatin; induces sleep, depresses neuronal activity; found in cortex, hippocampus.</p>Formula:C81H113N19O19S2Purezza:98%Colore e forma:SolidPeso molecolare:1721.01Azepexole hydrochloride
CAS:Azepexole hydrochloride (4H-Oxazolo[4,5-d]azepin-2-amine, 6-ethyl-5,6,7,8-tetrahydro-, hydrochloride (1:1)) is a potent α2-Adrenoceptor agonist with anaestheticFormula:C9H16ClN3OPurezza:99.88% - 99.89%Colore e forma:SoildPeso molecolare:217.7BAY-747
CAS:BAY-747: oral, brain-penetrant sGC stimulator; improves rat memory, cognition, lowers blood pressure, aids Duchenne muscular dystrophy.Formula:C22H26F2N4O2Colore e forma:SolidPeso molecolare:416.46PACAP (1-27), human, ovine, rat
CAS:PACAP (1-27) (the N-terminal fragment of PACAP-38) is a novel neuropeptides originally isolated from bovine hypothalamus, also found in humans and rats.Formula:C142H224N40O39SPurezza:98%Colore e forma:SolidPeso molecolare:3147.66Haloperidol D4
CAS:<p>Haloperidol D4 is deuterium-labeled haloperidol.</p>Formula:C21H23ClFNO2Purezza:98%Colore e forma:SolidPeso molecolare:379.89GLP-1R Agonist DMB
CAS:GLP-1R Agonist DMB is an agonist of glucagon-like peptide 1 receptor (GLP-1R; KB = 26.3 nM for the recombinant human receptor).Formula:C13H15Cl2N3O2SPurezza:99.52%Colore e forma:SolidPeso molecolare:348.25MrgprX2 antagonist-2
CAS:MrgprX2 antagonist-2, from patent WO2021092262A1 E163, is potent for skin inflammation studies.Formula:C17H16F5N3O3Colore e forma:SolidPeso molecolare:405.325MRS 2365
CAS:Highly potent, selective P2Y1 receptor agonistFormula:C13H19N5O9P2SPurezza:98%Colore e forma:SolidPeso molecolare:483.33Sarafotoxin S6a
CAS:Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo.Formula:C105H156N28O34S5Purezza:98%Colore e forma:SolidPeso molecolare:2514.85BIMU 8
CAS:BIMU 8 is a selective agonist of 5-HT4 with EC50s of 18 nM, 77 nM, and 540 nM for wild-type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4.Formula:C19H27ClN4O2Purezza:99.87%Colore e forma:SolidPeso molecolare:378.9ALD1613
<p>ALD1613 is a potent neutralizing monoclonal antibody targeting adrenocorticotropic hormone (ACTH). It neutralizes ACTH-induced signaling and inhibits cyclic adenosine monophosphate accumulation in ACTH-stimulated Y1 (mouse adrenal cell line) via all five melanocortin receptors. ALD1613 significantly reduces plasma corticosterone levels in wild-type rats and is applicable in studies involving elevated ACTH-related conditions.</p>Colore e forma:Odour LiquidSyk Inhibitor II hydrochloride
CAS:<p>Syk signaling is key in lupus. Syk inhibitors reduce inflammation and sepsis severity in FcgRIIb-/- mice, lowering cytokines and organ damage.</p>Formula:C14H16ClF3N6OPurezza:99.05%Colore e forma:SolidPeso molecolare:376.77Eledoisin
CAS:<p>Eledoisin (Eledone peptide) is a specific agonist of NK2 and NK3 receptors.Eledoisin is an undecapeptide of mollusk origin, belonging to the tachykinin family</p>Formula:C54H85N13O15SPurezza:98%Colore e forma:SolidPeso molecolare:1188.4JNJ-10181457 (hydrochloride)
CAS:JNJ-10181457 (hydrochloride) is a non-imidazole H3 receptor antagonist that is brain-penetrating and selective, increasing NE and acetylcholine concentrationsFormula:C20H30Cl2N2OColore e forma:SolidPeso molecolare:385.37[Nle11]-Substance P
CAS:<p>'[Nle11]-Substance P is a gut and brain peptide, resisting methionine oxidation and causing excitatory neural effects.'</p>Formula:C64H100N18O13Purezza:98%Colore e forma:SolidPeso molecolare:1329.59MD01-67
CAS:<p>MD01-67 is a macrocyclic compound selectively targeting the neurotensin 2 receptor (NTS2), with a Ki of 2.9 nM. It exhibits analgesic activity and reduces tactile hypersensitivity in rat models of acute, sustained, and chronic inflammatory pain.</p>Formula:C37H58N8O8Colore e forma:SolidPeso molecolare:742.91GLP-1 receptor agonist 13
Compound (S)-9, a GLP-1 receptor agonist, exhibits an EC50 of 76 nM for the glucagon GLP-1 receptor [1].Formula:C25H23ClF2N6OColore e forma:SolidPeso molecolare:496.94BMY-14802
CAS:BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.Formula:C18H22F2N4OPurezza:99.84%Colore e forma:SoildPeso molecolare:348.39Dexchlorpheniramine free base
CAS:<p>Dexchlorpheniramine Maleate, a histamine receptor antagonist, is used to treat urticaria, allergic rhinitis, allergic conjunctivitis and pruritus.</p>Formula:C16H19ClN2Purezza:98%Colore e forma:Oily Liquid SolidPeso molecolare:274.79
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