Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(942 prodotti)
- Recettore dell'adenosina(242 prodotti)
- Recettore adrenergico(2.949 prodotti)
- Recettore della bombesina(30 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(149 prodotti)
- CaSR(32 prodotti)
- Recettore dei cannabinoidi(195 prodotti)
- Recettore della dopamina(410 prodotti)
- Recettore dell'endotelina(75 prodotti)
- Recettore GNRH(73 prodotti)
- GPCR19(31 prodotti)
- GRK(32 prodotti)
- GTPase(21 prodotti)
- Recettore del glucagone(166 prodotti)
- Proteina Hedgehog/Smoothened(45 prodotti)
- Recettore dell'istamina(359 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(24 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(298 prodotti)
- PAFR(11 prodotti)
- PKA(49 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 18 più sottocategorie
Trovati 5378 prodotti di "Proteina G/GPCR"
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d[Leu4,Lys8]-VP acetate
<p>d[Leu4,Lys8]-VP acetate: Vasopressin V1b agonist. Ki: rat 0.16 nM, human 0.52 nM, mouse 1.38 nM. Low antidiuretic/vasopressor effects.</p>Formula:C49H71N11O13S2Purezza:98.86%Colore e forma:SolidPeso molecolare:1086.28Dalcotidine
CAS:<p>Dalcotidine (KU 1257), a histamine H2/H9 blocker, inhibits acid secretion; Ki=0.040, KB=0.041, aids ulcer healing, may lower relapse.</p>Formula:C18H29N3O2Purezza:99.11%Colore e forma:SolidPeso molecolare:319.44Survodutide TFA
<p>Survodutide TFA (BI 456906 TFA) is a GCGR/GLP-1R dual agonist, a peptide compound used in obesity research.</p>Formula:C192H289N47O61·xC2HF3OC2Purezza:99.29% - 99.96%Colore e forma:SolidPeso molecolare:4231.62 (free base)S1P2 antagonist 1
CAS:<p>S1P2 antagonist 1 is an orally bioavailable S1P2 antagonist against fibrotic diseases.</p>Formula:C23H21ClN4O4Colore e forma:SolidPeso molecolare:452.9N6-Benzyl-5'-ethylcarboxamido adenosine
CAS:<p>N6-Benzyl-5'-ethylcarboxamido adenosine is a selective A3 adenosine receptor agonist.</p>Formula:C19H22N6O4Colore e forma:SolidPeso molecolare:398.42MK-0493 HCl
CAS:<p>MK-0493 is a novel, potent, and selective agonist for melanocortin receptor 4 (MC4R).</p>Formula:C30H39Cl2F2N3O2Colore e forma:SolidPeso molecolare:582.55Maridebart
CAS:<p>Maridebart is a humanized IgG1-kappa monoclonal antibody that targets the GIPR (gastric inhibitory polypeptide receptor) [1].</p>Colore e forma:LiquidEdg-2 receptor inhibitor 1
CAS:<p>Edg-2 receptor inhibitor 1 (SAR-100842) is an Edg-2 receptor inhibitor extracted (IC50: <0.1 μM).</p>Formula:C27H27NO5Purezza:99.47%Colore e forma:SolidPeso molecolare:445.51GLP-1(7-37)
CAS:<p>GLP-1 (7-37) is a truncated, bioactive form of GLP-1 that is the product of proglucagon processing in intestinal endocrine L cells.</p>Formula:C151H228N40O47Purezza:98%Colore e forma:SolidPeso molecolare:3355.67(S)-Osanetant
CAS:<p>(S)-Osanetant, an S-enantiomer, is a selective NK3 antagonist with potential for treating schizophrenia and has anxiolytic and antidepressant effects.</p>Formula:C35H41Cl2N3O2Colore e forma:SolidPeso molecolare:606.62ARC 239 dihydrochloride
CAS:<p>ARC 239 dihydrochloride is a selective α2B adrenoceptor antagonist (pKD values are 8.8, 6.7 and 6.4 at α2B, α2A, and α2D receptors respectively).</p>Formula:C24H31Cl2N3O3Purezza:99.72%Colore e forma:SolidPeso molecolare:480.43Galantide acetate
<p>Galantide acetate, a non-specific galanin receptor antagonist, is a peptide consisting of fragments of galanin and substance P.</p>Formula:C106H155N25O28SPurezza:97.8% - 97.91%Colore e forma:SolidPeso molecolare:2259.58WAY-620645
CAS:WAY-620645 is a CCK antagonist with antitumor and analgesic activities.Formula:C22H22N4O2Purezza:99.89%Colore e forma:SolidPeso molecolare:374.44[D-Trp34]-Neuropeptide Y Acetate
<p>[D-Trp34]-Neuropeptide Y Acetate is a potent Y5 receptor agonist that increases rat food intake; less potent at Y1, Y2, Y4, Y6.</p>Formula:C198H293N55O58Purezza:99.73%Colore e forma:SoildPeso molecolare:4371.78Benzomalvin A
CAS:<p>Benzomalvin A is a filamentous fungal secondary metabolite.</p>Formula:C24H19N3O2Colore e forma:SolidPeso molecolare:381.43CB2 receptor agonist 2
CAS:<p>CB2 receptor agonist 2 (ZINC72105556): potent, Ki=8.5 nM, high selectivity for CB2.</p>Formula:C30H36N2O4Purezza:99.75%Colore e forma:SolidPeso molecolare:488.62SLB1122168 formic
<p>SLB1122168 is a potent inhibitor of Spns2-mediated sphingosine-1-phosphate (S1P) release, exhibiting an IC50 value of 94 nM [1].</p>Formula:C23H37N3O3Purezza:98%Colore e forma:SolidPeso molecolare:403.56S1R agonist 2 hydrochloride
<p>Compound 8b hydrochloride, a selective S1R agonist, exhibits affinity with K i s of 1.1 nM for S1R and 88 nM for S2R.</p>Formula:C21H28ClNOPurezza:98%Colore e forma:SolidPeso molecolare:345.91HTL22562
CAS:<p>HTL22562 is a calcitonin gene-related peptide (CGRP) receptor antagonist for acute treatment of migraine.</p>Formula:C40H49N11O5Colore e forma:SolidPeso molecolare:763.904Lys-γ3-MSH(human)
CAS:<p>Pro-opiomelanocortin (POMC) derived peptide that stimulates lipolysis</p>Formula:C128H193N45O39SPurezza:98%Colore e forma:SolidPeso molecolare:3018.25CCR4 antagonist 3 hydrochloride
CAS:<p>Orally active CCR4 antagonist 3 hydrochloride with potent selectivity, IC50s: 22/50 nM; has antitumor properties.</p>Formula:C24H27Cl2N7O·xHClColore e forma:SolidTHX-B
CAS:<p>THX-B, a potent non-peptidic p75 NTR antagonist, aids in researching diabetic kidney disease and neurodegenerative and inflammatory disorders.</p>Formula:C16H24N6O4Colore e forma:SolidPeso molecolare:364.4Albiglutide fragment TFA
<p>Albiglutide fragment (GLP-1 (7-36) analog) TFA represents a biologically active segment of Albiglutide, resistant to DPP-4 degradation due to its structure as a</p>Formula:C148H224N40O45·xC2HF3O2Colore e forma:SolidBIBP3226
CAS:<p>BIBP3226 is a potent and selective antagonist for the Neuropeptide Y receptor Y1 and the neuropeptide FF receptor.</p>Formula:C27H31N5O3Colore e forma:SolidPeso molecolare:473.57Bradykinin (1-7)
CAS:<p>Bradykinin (1-7), an amino-truncated peptide derived from Bradykinin, is a metabolite formed through enzymatic cleavage by endopeptidase.</p>Formula:C35H52N10O9Purezza:98%Colore e forma:White Lyophilized PowderPeso molecolare:756.85Nα-Methylhistamine FA
<p>Nα-Methylhistamine FA is a histamine H3 receptor agonist</p>Formula:C7H13N3O2Purezza:>99.99%Colore e forma:SolidPeso molecolare:171.2PACAP (6-38), human, ovine, rat acetate
<p>PACAP (6-38), human, ovine, rat acetate is a potent PACAP receptor antagonist with IC50s of 30, 600, and 40 nM for PACAP type I receptor, PACAP type II receptor</p>Formula:C184H303N55O48SPurezza:99.84%Colore e forma:SoildPeso molecolare:4085.84Calcitonin (8-32), salmon
CAS:Calcitonin (8-32), salmon: selective amylin receptor antagonist, regulates calcium/phosphorus, thyroid origin, 32-aa peptide.Formula:C119H198N36O37Purezza:98%Colore e forma:SolidPeso molecolare:2725.06Anthramycin
CAS:<p>Anthramycin: a PBD family antibiotic with antitumor effects and CNS cholecystokinin antagonist properties in mice.</p>Formula:C16H17N3O4Colore e forma:SolidPeso molecolare:315.32Fluphenazine free base
CAS:<p>Flufenazine: antipsychotic for schizophrenia, blocks dopamine D2 receptors, reduces hallucinations and delusions.</p>Formula:C22H26F3N3OSColore e forma:SolidPeso molecolare:437.52PA-8
CAS:<p>PA-8: Selective PAC1 antagonist, orally active, blocks CREB phosphorylation & cAMP increase (IC50=2nM), reduces pain & aversive response in vivo.</p>Formula:C17H18N4O4Purezza:97.64%Colore e forma:SolidPeso molecolare:342.35PACAP-38 (31-38), human, mouse, rat acetate
<p>PACAP-38 (31-38) acetate stimulates PAC1 receptor and boosts NPY and catecholamine in sympathetic neurons.</p>Formula:C49H87N17O13Purezza:99.92%Colore e forma:SolidPeso molecolare:1122.32Human growth hormone-releasing factor
CAS:<p>GHRH from the hypothalamus prompts the pituitary to produce/release GH by attaching to the GHRHR.</p>Formula:C215H358N72O66SPurezza:98%Colore e forma:SolidPeso molecolare:5039.65Albenatide
CAS:<p>Albenatide is a modified analog of exendin 4 conjugated to recombinant human albumin.</p>Formula:C26H47N7O9SPurezza:98%Colore e forma:SolidPeso molecolare:633.76Lobeline sulfate
CAS:<p>Lobeline sulfate, an alkaloid like nicotine, aids in smoking cessation, insomnia, and respiratory issues. Less potent on nicotinic receptors.</p>Formula:C22H29NO6SPurezza:98%Colore e forma:White PowderPeso molecolare:435.54NPC 567
CAS:<p>NPC 567 is an antagonist of the bradykinin receptor.</p>Formula:C60H87N19O13Purezza:98%Colore e forma:SolidPeso molecolare:1282.48ELA-21 (human)
CAS:<p>Apelin receptor agonist with high affinity for normal/PAH hearts (pKi 9.31/9.46). Blocks cAMP, promotes β-arrestin in vitro. Part of ELA-32.</p>Formula:C112H184N40O25S3Purezza:98%Colore e forma:SolidPeso molecolare:2587.12Pal-Glu(OSu)-OH
CAS:<p>Pal-Glu(OSu)-OH is a Liraglutide side chain, a GLP-1 agonist for type 2 diabetes study.</p>Formula:C25H42N2O7Colore e forma:SolidPeso molecolare:482.618Vilanterol
CAS:<p>Vilanterol is a selective long-acting beta2-adrenergic agonist (LABA) used in the treatment of COPD and asthma.</p>Formula:C24H33Cl2NO5Purezza:97.47% - 99.46%Colore e forma:SolidPeso molecolare:486.43N,N′-Diferuloylputrescine
CAS:<p>N,N′-Diferuloylputrescine acts as a pigment inhibitor, showing a 57% reduction in pigmentation.</p>Formula:C24H28N2O6Purezza:98%Colore e forma:SolidPeso molecolare:440.49HAEGTFTSD acetate(926018-45-3 free base)
HAEGTFTSD acetate is the first N-terminal 1-9 residues of GLP-1 peptide.The GLP-1 (7-36) amide is a product of the preproglucagon gene, which is secreted fromFormula:C42H61N11O19Purezza:98%Colore e forma:SolidPeso molecolare:1024.01Parstatin(human)
CAS:Cell-permeable PAR1-derived peptide; inhibits endothelial migration, proliferation (IC50 ~3μM), induces apoptosis, and has cardioprotective effects.Formula:C191H330N64O53S3Purezza:98%Colore e forma:SolidPeso molecolare:4467.29HHS-0701
CAS:HHS-0701: SuTEx ligand, strong PTGR2 inhibitor, blocks 15-Keto-PGE2 metabolism.Formula:C20H20N4O3SPurezza:97.24%Colore e forma:SoildPeso molecolare:396.46hNTS1R agonist-1
<p>Compound 10, an hNTS1R agonist-1, acts as a full agonist with a strong affinity for hNTS1R (K i: 6.9 nM), showing the ability to cross the blood-brain barrier (</p>Formula:C37H62N10O9Purezza:98%Colore e forma:SolidPeso molecolare:790.9517-trifluoromethylphenyl trinor Prostaglandin F2α
CAS:<p>A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma.</p>Formula:C24H31F3O5Colore e forma:SolidPeso molecolare:456.502Galanin-Like Peptide (porcine)
CAS:<p>Galanin-Like Peptide (porcine) is a 60 amino acid neuropeptide originally isolated from the porcine hypothalamus.</p>Formula:C281H443N81O78Purezza:98%Colore e forma:SolidPeso molecolare:6204.02Neuropeptide S(Rat)
CAS:<p>Potent endogenous neuropeptide S receptor (NSPR) agonist (EC50 = 3.2 nM).</p>Formula:C95H160N34O27Purezza:98%Colore e forma:SolidPeso molecolare:2210.52AD186
<p>AD186, a potent and selective S1R agonist, exhibits dissociation constants (Kis) of 2.7 nM for S1R and 27 nM for S2R.</p>Formula:C22H28N2Purezza:98%Colore e forma:SolidPeso molecolare:320.47Ala5-Galanin (2-11)
CAS:<p>Ala5-Galanin (2-11) is a specific agonist for the galanin receptor 2 (GAL2R) with an affinity constant (Ki) of 258 nM [1].</p>Formula:C54H81N13O13Purezza:98%Colore e forma:SolidPeso molecolare:1120.3RFRP-3(human)
CAS:<p>NPFF1 receptor agonist, IC50 0.7 nM, blocks cAMP by forskolin. A GnIH homolog, it inhibits GnRH neuron activity.</p>Formula:C45H72N14O10Purezza:98%Colore e forma:SolidPeso molecolare:969.15
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