Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(939 prodotti)
- Recettore dell'adenosina(242 prodotti)
- Recettore adrenergico(2.945 prodotti)
- Recettore della bombesina(30 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(148 prodotti)
- CaSR(32 prodotti)
- Recettore dei cannabinoidi(195 prodotti)
- Recettore della dopamina(407 prodotti)
- Recettore dell'endotelina(76 prodotti)
- Recettore GNRH(73 prodotti)
- GPCR19(31 prodotti)
- GRK(31 prodotti)
- GTPase(21 prodotti)
- Recettore del glucagone(165 prodotti)
- Proteina Hedgehog/Smoothened(44 prodotti)
- Recettore dell'istamina(358 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(24 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(297 prodotti)
- PAFR(11 prodotti)
- PKA(48 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 18 più sottocategorie
Trovati 5352 prodotti di "Proteina G/GPCR"
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Chlorprothixene hydrochloride
CAS:<p>Chlorprothixene hydrochloride, a typical antipsychotic, blocks 5-HT2, D1-D3, H1, muscarinic, and alpha1 receptors.</p>Formula:C18H18ClNS·HClPurezza:99.76%Colore e forma:White PowderPeso molecolare:352.32Azatadine dimaleate
CAS:<p>Azatadine dimaleate (SCH10649) is an inhibitor for histamine（IC50=6.5 nM） and cholinergic（IC50=10 nM）.</p>Formula:C28H30N2O8Purezza:99.7% - >99.99%Colore e forma:PowderPeso molecolare:522.55Olanzapine
CAS:<p>Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.</p>Formula:C17H20N4SPurezza:99.86% - ≥95%Colore e forma:Yellowish Crystalline PowderPeso molecolare:312.43CP-809101 hydrochloride
CAS:<p>CP-809101 hydrochloride is a potent and selective 5-HT2C receptor agonist (pEC50: 9.96/7.19/6.81 for human 5-HT2C/5-HT2B/5-HT2A receptors).</p>Formula:C15H18Cl2N4OPurezza:99.5%Colore e forma:SolidPeso molecolare:341.24Trazodone hydrochloride
CAS:<p>Trazodone hydrochloride (Trazodone HCl) is a serotonin uptake inhibitor that is used as an antidepressive agent.</p>Formula:C19H23Cl2N5OPurezza:99.5% - 99.52%Colore e forma:SolidPeso molecolare:408.33MK-0249 FA
<p>MK-0249 FA is an H3 inverse agonist that can be used to study attention-deficit, hyperactivity disorder and cognitive disorders in adults.</p>Formula:C24H26F3N3O4Purezza:99.98%Colore e forma:SolidPeso molecolare:477.48Antazoline hydrochloride
CAS:<p>Antazoline hydrochloride (Phenazoline hydrochloride), a first-generation antihistamine, can bind to the histamine H1 receptor and block the action of endogenous</p>Formula:C17H19N3·HClPurezza:98% - 99.53%Colore e forma:White Or Almost White Crystalline PowderPeso molecolare:301.82Brefonalol HCl
<p>Brefonalol HCl, ADRA blocker for neurological/cardiovascular issues, treats angina, arrhythmias, hypertension.</p>Formula:C22H29ClN2O2Purezza:99.45%Colore e forma:SolidPeso molecolare:388.93Aripiprazole
CAS:<p>Aripiprazole (OPC-14597) is a piperazine/quinolone antipsychotic, partial agonist at 5-HT1A/D2, and antagonist at 5-HT2A.</p>Formula:C23H27Cl2N3O2Purezza:99.43% - 99.62%Colore e forma:Colourless Flake Crystalline SolidPeso molecolare:448.39YNT-185
CAS:<p>YNT-185 is a nonpeptide, selective agonist of the orexin type-2 receptor (OX2R), demonstrating EC50 values of 0.028 μM and 2.75 μM for OX2R and OX1R,</p>Formula:C33H37N5O5SPurezza:99.67%Colore e forma:SolidPeso molecolare:615.74Alverine citrate
CAS:<p>Alverine citrate (NSC 35459) is utilized in functional gastrointestinal disorders.</p>Formula:C26H35NO7Purezza:98.53% - 99.43%Colore e forma:CoaPeso molecolare:473.57KGA-2727
CAS:<p>KGA-2727: potent, selective SGLT1 inhibitor (human Ki 97.4 nM, rat 43.5 nM), with high selectivity over SGLT2 for diabetes treatment.</p>Formula:C26H40N4O8Purezza:98.46%Colore e forma:SolidPeso molecolare:536.62(3aR,9aR)-Fluparoxan
CAS:<p>(3aR,9aR)-Fluparoxan is a highly selective and potent adrenergic receptor α2B antagonist for the prevention, amelioration or treatment of neurodevelopmental</p>Formula:C10H10FNO2Purezza:97.82%Colore e forma:SoildPeso molecolare:195.19Ticlopidine hydrochloride
CAS:<p>Ticlopidine hydrochloride (Ticlodix) is an effective inhibitor of platelet aggregation commonly used in the placement of STENTS in CORONARY ARTERIES.</p>Formula:C14H15Cl2NSPurezza:99.85% - >99.99%Colore e forma:White PowderPeso molecolare:300.25Zolmitriptan
CAS:<p>Zolmitriptan targets 5-HT 1B/1D receptors, constricts cranial vessels, inhibits pain signals, and stops pro-inflammatory neuropeptides, alleviating migraines.</p>Formula:C16H21N3O2Purezza:99.69% - 99.91%Colore e forma:White Or Kind Of White PowderPeso molecolare:287.36Adenosine A1 receptor activator T62
CAS:<p>Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and also</p>Formula:C15H14ClNOSPurezza:97.83%Colore e forma:SolidPeso molecolare:291.8AH 6809
CAS:<p>AH 6809 blocks EP1, EP2, EP3, DP receptors (Ki: 1217-1597 nM human, 350 nM mouse EP2).</p>Formula:C17H14O5Purezza:97.59%Colore e forma:SolidPeso molecolare:298.29Phenothiazine
CAS:<p>Phenothiazine (ENT 38) is a class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities.</p>Formula:C12H9NSPurezza:99.95%Colore e forma:Yellow Solid PelletsPeso molecolare:199.27Noradrenaline bitartrate
CAS:<p>Norepinephrine bitartrate acts directly on the α- and β-adrenergic receptors.</p>Formula:C12H19NO10Purezza:99.53% - >99.99%Colore e forma:SolidPeso molecolare:337.28ESI-05
CAS:<p>ESI-05 (NSC-116966) is a specific 0.4 μM IC50 EPAC2 antagonist that blocks cAMP-induced EPAC2 and Rap1 activation.</p>Formula:C16H18O2SPurezza:97.22%Colore e forma:SolidPeso molecolare:274.38SR59230A
CAS:<p>SR59230A is a potent, selective antagonist of β3-adrenergic receptor(β3, β1, and β2 receptors with IC50s of 40, 408, and 648 nM , respectively).</p>Formula:C23H29NO6Purezza:98.84%Colore e forma:SolidPeso molecolare:415.48Levocetirizine
CAS:<p>Levocetirizine is a Histamine-1 Receptor Antagonist. The mechanism of action of levocetirizine is as a Histamine H1 Receptor Antagonist.</p>Formula:C21H25ClN2O3Purezza:98% - 99.9%Colore e forma:White PowderPeso molecolare:388.89RS102895 hydrochloride
CAS:<p>RS102895 hydrochloride is a potent antagonist of CCR2(IC50 of 360 nM).</p>Formula:C21H22ClF3N2O2Purezza:98.95%Colore e forma:SolidPeso molecolare:426.86LCKLSL hydrochloride
<p>LCKLSL hydrochloride is an AnxA2 inhibitor with potential anti-angiogenic activity and inhibits the development of EAE.</p>Formula:C30H58ClN7O8SPurezza:98.02% - 99.31%Colore e forma:SolidPeso molecolare:712.34(R)-Elagolix
CAS:<p>(R)-Elagolix (NBI-56418) is an orally active, highly selective, short-term potent antagonist of the non-peptide gonadotropin-releasing hormone receptor.</p>Formula:C32H30F5N3O5Purezza:99.08%Colore e forma:SolidPeso molecolare:631.59Ezlopitant
CAS:<p>Ezlopitant (CJ-11974) is a small molecule neurokinin-1-receptor (NK1) antagonist used to treat nausea, vomiting and pain.</p>Formula:C31H38N2OPurezza:97.49%Colore e forma:SolidPeso molecolare:454.65JP1302 dihydrochloride
CAS:<p>JP1302 dihydrochloride: selective α2C-adrenoceptor antagonist; Ki=28 nM, Kb=16 nM.</p>Formula:C24H26Cl2N4Purezza:99.61%Colore e forma:SolidPeso molecolare:441.4BIBO3304 TFA
CAS:<p>BIBO3304 TFA: Oral, selective NPY Y1 receptor blocker; IC50: 0.38 nM (human), 0.72 nM (rat).</p>Formula:C31H36F3N7O5Purezza:99.5%Colore e forma:SolidPeso molecolare:643.66Filorexant
CAS:<p>Filorexant (MK-6096) is an orally bioavailable effective and selective reversible antagonist of OX1 and OX2 receptor with (Ki <3 nM).</p>Formula:C24H25FN4O2Purezza:98.88%Colore e forma:SolidPeso molecolare:420.48Levodropropizine
CAS:<p>Levodropropizine ((S)-(-)-Dropropizine) is a histamine receptor inhibitor. It is used as an effective and very well tolerated peripheral antitussive drug.</p>Formula:C13H20N2O2Purezza:99.87% - 99.93%Colore e forma:White Or Off White Crystalline PowderPeso molecolare:236.31Palonosetron hydrochloride
CAS:<p>Palonosetron hydrochloride (RS 25259) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.</p>Formula:C19H24N2O·HClPurezza:99.84% - 99.92%Colore e forma:White SolidPeso molecolare:332.87Ro 10-5824 dihydrochloride
CAS:<p>Ro 10-5824 dihydrochloride is a selective agonist of dopamine D4 receptor partial, (Ki of 5.2 nM).</p>Formula:C17H22Cl2N4Purezza:99.79%Colore e forma:SolidPeso molecolare:353.29Moxisylyte hydrochloride
CAS:<p>Moxisylyte hydrochloride (Thymoxamine hydrochloride) is an alpha-adrenergic blocking agent that is used in Raynaud's disease.</p>Formula:C16H26ClNO3Purezza:99.93% - ≥95%Colore e forma:SolidPeso molecolare:315.84Ziprasidone hydrochloride
CAS:<p>Ziprasidone hydrochloride (CP-88059 hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic</p>Formula:C21H22CL2N4OSPurezza:97.97% - 99.82%Colore e forma:SolidPeso molecolare:449.4Vilazodone
CAS:<p>Vilazodone (SB659746A): an SSRI and 5-HT-1A agonist, boosts serotonin to treat depression and anxiety.</p>Formula:C26H27N5O2Purezza:99.61%Colore e forma:Light Yellow SolidPeso molecolare:441.52Dopexamine hydrochloride
CAS:<p>Dopexamine hydrochloride (FPL60278AR) is a β2-adrenoceptor agonist that modulates inflammation and protects organs without affecting hemodynamics.</p>Formula:C22H34Cl2N2O2Purezza:98.55%Colore e forma:SolidPeso molecolare:429.42Dimenhydrinate
CAS:<p>Dimenhydrinate (Vomex A) is an ethanolamine and histamine antagonist with anti-allergic activity.</p>Formula:C24H28ClN5O3Purezza:99.57% - 99.77%Colore e forma:Crystals Physical Description Crystalline White Powder (Ntp 1992)Peso molecolare:469.96Adrenalone hydrochloride
CAS:<p>Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.</p>Formula:C9H11NO3·HClPurezza:99.94%Colore e forma:SolidPeso molecolare:217.65Heptaminol hydrochloride
CAS:<p>Heptaminol hydrochloride (RP-2831 hydrochloride), a vasoconstrictor, is used in the therapy of hypotension, especially orthostatic hypotension.</p>Formula:C8H20ClNOPurezza:98.61%Colore e forma:White Crystalline PowderPeso molecolare:181.71Promazine hydrochloride
CAS:<p>Promazine hydrochloride, a phenothiazine less potent than chlorpromazine, treats disturbed behavior and nausea.</p>Formula:C17H21ClN2SPurezza:99.90%Colore e forma:SolidPeso molecolare:320.88Acebutolol hydrochloride
CAS:<p>Acebutolol HCl: cardioselective beta-blocker, minimal bronchial impact, intrinsic sympathomimetic, treats hypertension & ventricular arrhythmias.</p>Formula:C18H29ClN2O4Purezza:99.92% - >99.99%Colore e forma:White Or Slightly Off-White Crystalline Powder SolidPeso molecolare:372.89Pizotifen
CAS:<p>Pizotifen is a serotonin antagonist with mild anticholinergic effects, used in migraine prevention. Not available in the USA.</p>Formula:C19H21NSPurezza:99.93%Colore e forma:SolidPeso molecolare:295.44Linaclotide
CAS:<p>Linaclotide treats IBS-C & chronic constipation; it's a selective guanylate cyclase C agonist.</p>Formula:C59H79N15O21S6Purezza:97.93% - 98.71%Colore e forma:SolidPeso molecolare:1526.74MP-A08
CAS:<p>MP-A08 selectively inhibits SPHK1; targets SphK1 & SphK2 with Ki of 6.9 μM & 27 μM, respectively.</p>Formula:C27H25N3O4S2Purezza:97.44%Colore e forma:SolidPeso molecolare:519.64Fenspiride hydrochloride
CAS:<p>Fenspiride HCl treats respiratory diseases including asthma and ENT inflammation in Russia.</p>Formula:C15H20N2O2·HClPurezza:99.64% - 99.92%Colore e forma:SolidPeso molecolare:296.79Fezolinetant
CAS:<p>Fezolinetant (ESN-364) is a neurokinin-3 receptor antagonist that is being investigated for menopausal hot flashes.Cost-effective and quality-assured.</p>Formula:C16H15FN6OSPurezza:98.62% - 99.7%Colore e forma:SolidPeso molecolare:358.39Cetirizine dihydrochloride
CAS:Cetirizine dihydrochloride is a potent non-drowsy antihistamine for allergies and asthma.Formula:C21H27Cl3N2O3Purezza:99.4% - 99.97%Colore e forma:SolidPeso molecolare:461.81Olinciguat
CAS:<p>Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator.</p>Formula:C21H16F5N7O3Purezza:99.33% - 99.71%Colore e forma:SolidPeso molecolare:509.39Roxatidine Acetate hydrochloride
CAS:<p>Roxatidine Acetate hydrochloride (HOE 760) is a specific and competitive histamin H2-receptor antagonist. Roxatidine inhibits gastric acid secretion.</p>Formula:C19H29ClN2O4Purezza:99.49%Colore e forma:SolidPeso molecolare:384.9Monatepil 2maleate
<p>Monatepil 2maleate is an orally active Ca2+-channel antagonist and ACAT inhibitor with alpha(1)-adrenergic receptor blocking activity and antiarrhythmic properties that inhibit vasoconstriction.Monatepil 2maleate may be used to study atherosclerosis.</p>Formula:C32H34FN3O5SPurezza:98%Colore e forma:SolidPeso molecolare:591.69
