Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(939 prodotti)
- Recettore dell'adenosina(242 prodotti)
- Recettore adrenergico(2.945 prodotti)
- Recettore della bombesina(30 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(148 prodotti)
- CaSR(32 prodotti)
- Recettore dei cannabinoidi(195 prodotti)
- Recettore della dopamina(407 prodotti)
- Recettore dell'endotelina(76 prodotti)
- Recettore GNRH(73 prodotti)
- GPCR19(31 prodotti)
- GRK(31 prodotti)
- GTPase(21 prodotti)
- Recettore del glucagone(165 prodotti)
- Proteina Hedgehog/Smoothened(44 prodotti)
- Recettore dell'istamina(358 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(24 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(297 prodotti)
- PAFR(11 prodotti)
- PKA(48 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 18 più sottocategorie
Trovati 5352 prodotti di "Proteina G/GPCR"
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Aprocitentan
CAS:<p>Aprocitentan (ACT-132577) is ETA and ETB antagonist .</p>Formula:C16H14Br2N6O4SPurezza:99.17%Colore e forma:SolidPeso molecolare:546.19Raclopride tartrate
CAS:<p>Raclopride is a selective antagonist on D2 dopamine receptor ( D2 Ki: 1.8 nm, D3 Ki: 3.5 nm, D4 Ki: 2400, D1 Ki: 18000 nM).</p>Formula:C19H26Cl2N2O9Colore e forma:SolidPeso molecolare:497.32Ertugliflozin
CAS:<p>PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).</p>Formula:C22H25ClO7Purezza:99.89% - 99.96%Colore e forma:SolidPeso molecolare:436.88R715 TFA(185052-09-9 free base)
<p>R715 TFA(185052-09-9 free base) is a potent and selective bradykinin B1 receptor antagonist (pA2 = 8.49).</p>Formula:C59H82F3N13O14Purezza:>99.99%Colore e forma:SolidPeso molecolare:1254.36Clozapine N-Oxide
CAS:<p>View and buy CLOZAPINE N-OXIDE from TargetMol.Clozapine N-oxide is a major metabolite of clozapine also known as DREADDs, technology to modulate synthetic receptors in vivo.Cited in 2 publications.</p>Formula:C18H19ClN4OPurezza:98.43% - 99.94%Colore e forma:SolidPeso molecolare:342.82[D-Phe12,Leu14]-Bombesin acetate
<p>[D-Phe12,Leu14]-Bombesin acetate inhibits bombesin-stimulated secretion.</p>Formula:C77H118N22O20Purezza:98.41% - 99.14%Colore e forma:SolidPeso molecolare:1671.9Cenicriviroc
CAS:<p>Cenicriviroc (TAK-652), oral CCR2/CCR5 blocker, inhibits HIV-1/HIV-2, with strong anti-infective/anti-inflammatory effects.</p>Formula:C41H52N4O4SPurezza:97.87%Colore e forma:SolidPeso molecolare:696.94MDL 100009
CAS:<p>MDL 100009, the S-enantiomer of MDL 100151 and the opposite enantiomer of MDL 100907, is a selective antagonist of 5-HT2A.</p>Formula:C22H28FNO3Purezza:98.96%Colore e forma:SolidPeso molecolare:373.46RU 24969 succinate
CAS:<p>RU 24969 succinate, a 5-HT receptor agonist, exhibits K i values of 0.38 nM for 5-HT 1B and 2.5 nM for 5-HT 1A, indicating its affinity towards these receptors. It reduces fluid consumption and enhances forward locomotion. This compound is utilized in neurological disease research.</p>Formula:C18H22N2O5Colore e forma:SolidPeso molecolare:346.38Naratriptan hydrochloride
CAS:<p>Naratriptan Hydrochloride, a selective 5-HT1 receptor agonist with anti-migraine effect, induces vasoconstriction and reduces inflammation in migraines.</p>Formula:C17H25N3O2S·HClPurezza:99.17% - 99.93%Colore e forma:Beige SolidPeso molecolare:371.93BRL-15572 hydrochloride
CAS:<p>BRL-15572 hydrochloride: selective h5-HT1D antagonist with high affinity; useful for studying h5-HT1D responses.</p>Formula:C25H28Cl2N2OColore e forma:SolidPeso molecolare:443.41Maraviroc
CAS:<p>Maraviroc: a CCR5 antagonist blocking HIV-1 entry; IC50s—MIP-1α: 3.3nM, MIP-1β: 7.2nM, RANTES: 5.2nM.</p>Formula:C29H41F2N5OPurezza:97.13% - 99.59%Colore e forma:Brown SolidPeso molecolare:513.67Lofexidine
CAS:<p>Lofexidine is a selective α2-receptor agonist, Lofexidine reduces narcotic withdrawal symptoms.</p>Formula:C11H12Cl2N2OPurezza:98.78%Colore e forma:SolidPeso molecolare:259.13Midaglizole
CAS:<p>Midaglizole, an α2-adrenoceptor blocker, raises blood pressure and lowers glucose.</p>Formula:C16H17N3Colore e forma:SolidPeso molecolare:251.33Cangrelor free acid
CAS:<p>Cangrelor, a reversible P2Y12 inhibitor for IV use, was approved in June 2015; it rapidly blocks ADP-induced platelet aggregation.</p>Formula:C17H25Cl2F3N5O12P3S2Colore e forma:SolidPeso molecolare:776.36Isocorynoxeine
CAS:<p>Isocorynoxeine reduces blood pressure, dilates vessels, and guards neurons against ischemia and glutamate toxicity.</p>Formula:C22H26N2O4Purezza:98% - 99.9%Colore e forma:SolidPeso molecolare:382.45Eltoprazine dihydrochloride
CAS:<p>Eltoprazine dihydrochloride, a drug developed for aggression, is now studied for L-DOPA-induced dyskinesia in Parkinson's.</p>Formula:C12H18Cl2N2O2Purezza:99.64%Colore e forma:SolidPeso molecolare:293.19F-15599
CAS:<p>F-15599 is a highly selective G-protein biased 5-HT1A receptor agonist(Ki : 3.4 nM).</p>Formula:C19H21ClF2N4OPurezza:98.72%Colore e forma:SolidPeso molecolare:394.854-Methylhistamine hydrochloride
CAS:<p>Compound with imidazole ring & amine group; inhibits copper enzymes, affects gene expression.</p>Formula:C6H12ClN3Purezza:95%Colore e forma:SolidPeso molecolare:161.633Butyrophenone
CAS:<p>Butyrophenone (NSC-8463) is a chemical compound. Some of its derivatives are used to treat various psychiatric disorders.</p>Formula:C10H12OPurezza:99.84%Colore e forma:Colourless To Yellow LiquidPeso molecolare:148.2ABT-702 dihydrochloride
CAS:<p>ABT-702 dihydrochloride is a potent adenosine kinase (AK) inhibitor.</p>Formula:C22H21BrCl2N6OPurezza:98.42% - 98.98%Colore e forma:SolidPeso molecolare:536.25BCTC
CAS:<p>BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 (IC50 of 35 and 6 nM, respectively)</p>Formula:C20H25ClN4OPurezza:99.21%Colore e forma:SolidPeso molecolare:372.89S 38093
CAS:<p>S 38093 is a brain-penetrant antagonist of the H3 receptor (Ki: 8.8/1.44/1.2 μM, for rat/mouse/human).</p>Formula:C17H24N2O2Purezza:99.95%Colore e forma:SolidPeso molecolare:288.38Isoetharine mesylate salt
CAS:<p>Isoetharine mesylate salt (Isoetarine mesilate) is a β-adrenergic receptor agonist.</p>Formula:C14H25NO6SPurezza:99.35% - 99.75%Colore e forma:SolidPeso molecolare:335.42Bepotastine Besilate
CAS:<p>Bepotastine Besilate (TAU 284) is a non-sedating and selective H1 receptor antagonist (pIC50: 5.7).</p>Formula:C21H25ClN2O3·C6H6O3SPurezza:99.83% - 99.9%Colore e forma:Brown Viscous LiquidPeso molecolare:547.06CP 376395
CAS:<p>CP 376395 (CP-316311) is an effective and specific Corticotropin-releasing factor 1 (CRF1) receptor antagonist.</p>Formula:C21H30N2OPurezza:99.86% - 99.94%Colore e forma:SolidPeso molecolare:326.48CYM5442
CAS:<p>CYM5442 is an S1P agonist, targeting to Sphingosine.</p>Formula:C23H27N3O4Purezza:98.02% - 99.48%Colore e forma:SolidPeso molecolare:409.48Tripelennamine citrate
CAS:<p>Tripelennamine citrate, an ethylenediamine derivative, blocks H1 receptors to treat allergies and anaphylaxis.</p>Formula:C22H29N3O7Colore e forma:SolidPeso molecolare:447.488Melitracen hydrochloride
CAS:Melitracen hydrochloride (Thymeol hydrochloride) , an antidepressant, is used as potential dopamine D1/2 receptor antagonist to treat depression.Formula:C21H26ClNPurezza:99.99%Colore e forma:Crystalline SolidPeso molecolare:327.90Haloperidol decanoate
CAS:<p>Haloperidol decanoate (KD 16), an antipsychotic, treats schizophrenia and mood disorders as an intramuscular ester.</p>Formula:C31H41ClFNO3Purezza:99.57% - 99.72%Colore e forma:SolidPeso molecolare:530.11Anisotropine Methylbromide
CAS:<p>Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.</p>Formula:C17H32BrNO2Purezza:99.73%Colore e forma:Crystals From Acetone SolidPeso molecolare:362.35Triprolidine hydrochloride
CAS:<p>Triprolidine hydrochloride anhydrous, a Histamine H1 antagonist, is used in asthma, allergic rhinitis, and urticaria.</p>Formula:C19H23ClN2Colore e forma:SolidPeso molecolare:314.852Ibutamoren
CAS:<p>Ibutamoren (MK-677) is a drug which acts as a potent, orally active growth hormone secretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin. It also alters the metabolism of body fat and so may have an application in the treatment of obesity.</p>Formula:C27H36N4O5SPurezza:97.59%Colore e forma:SolidPeso molecolare:528.66RS 100329
CAS:<p>RS 100329 HCl is a selective α1A-adrenoceptor antagonist (pKi = 9.6 for human cloned α1A receptors).</p>Formula:C20H25F3N4O3Colore e forma:SolidPeso molecolare:426.43Cetirizine Impurity B dihydrochloride
CAS:<p>Cetirizine Impurity B dihydrochloride is a Cetirizine antihistamine byproduct with anti-allergic properties.</p>Formula:C19H23Cl3N2O2Purezza:99.24%Colore e forma:SolidPeso molecolare:417.76S 38093 HCl
CAS:<p>S 38093 is a novel brain-penetrant antagonist/inverse agonist of H3 receptors.</p>Formula:C17H25ClN2O2Purezza:97.91%Colore e forma:SolidPeso molecolare:324.85PF-06291874
CAS:<p>PF-06291874 (Glucagon receptor antagonists-4) (Glucagon receptor antagonists-4) is a highly effective and orally active antagonist of the glucagon receptor.</p>Formula:C26H28F3N3O4Purezza:99.12% - 99.27%Colore e forma:SolidPeso molecolare:503.51Triprolidine
CAS:<p>Triprolidine: oral H1 receptor blocker with motor/sensory spinal effects, for allergy research.</p>Formula:C19H22N2Colore e forma:SolidPeso molecolare:278.39SCH-23390 hydrochloride
CAS:<p>SCH-23390 hydrochloride (R-(+)-SCH23390 hydrochloride) is an effective dopamine receptor antagonist, and for the D1(Ki=0.2 nM) and D5(Ki=0.3 nM).</p>Formula:C17H19Cl2NOPurezza:98% - 99.83%Colore e forma:SolidPeso molecolare:324.24Ajmalicine hydrochloride
CAS:<p>Ajmalicine hydrochloride is a potent α1-adrenoceptor blocker, non-competitive nicotine receptor inhibitor, anti-hypertensive, and sedative. IC50: 72.3 μM.</p>Formula:C21H25ClN2O3Colore e forma:SolidPeso molecolare:388.89Vilazodone Hydrochloride
CAS:<p>Vilazodone Hydrochloride (EMD 68843) , a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of the</p>Formula:C26H27N5O2·HClPurezza:99.56% - >99.99%Colore e forma:SolidPeso molecolare:477.99ARC-239
CAS:<p>ARC-239 is an agonist of α2-adrenergic receptor.</p>Formula:C24H29N3O3Colore e forma:SolidPeso molecolare:407.51PF3274167
CAS:PF3274167 (Cligosiban) is a potent and selective, high-affinity nonpeptide oxytocin receptor antagonist.Formula:C19H19ClFN5O3Purezza:99.67% - 99.88%Colore e forma:SolidPeso molecolare:419.84THIQ
CAS:<p>THIQ is a selective melanocortin-4 receptor (MC4R) agonist (hMC4R and rMC4R with IC50 of 1.2 nM and 0.6 nM , respectively).</p>Formula:C33H41ClN6O2Purezza:98.93%Colore e forma:SolidPeso molecolare:589.17SBI-553
CAS:<p>SBI-553 is an effective and brain penetrant NTR1 allosteric modulator (EC50: 0.34 μM).</p>Formula:C26H31FN4O2Purezza:99.33%Colore e forma:SolidPeso molecolare:450.55Fluoroclebopride
CAS:<p>Fluoroclebopride is a dopamine (DA) D2 receptor ligand.</p>Formula:C20H23ClFN3O2Purezza:99.68% - 99.91%Colore e forma:SolidPeso molecolare:391.87GBR 12935
CAS:<p>GBR-12935: selective dopamine inhibitor, used in Parkinson's research.</p>Formula:C28H34N2OColore e forma:SolidPeso molecolare:414.58Zafirlukast
CAS:<p>Zafirlukast (ICI 204219) is an orally leukotriene D4 receptor (LTD4) antagonist. Zafirlukast has anti-asthmatic and anti-inflammatory effects. Cost-effective and quality-assured.</p>Formula:C31H33N3O6SPurezza:99% - 99.83%Colore e forma:SolidPeso molecolare:575.68M 1145 acetate
<p>M1145 acetate: chimeric peptide, selective GAL2 agonist, Ki=6.55 nM; >90x affinity vs GAL1, 76x vs GalR3. Enhances galanin signal.</p>Formula:C130H209N37O34Purezza:99.1%Colore e forma:SolidPeso molecolare:2834.28CJC-1295 acetate(863288-34-0 free base)
<p>CJC-1295 acetate is a synthetic GHRH analogue and GHS.</p>Formula:C154H256N44O44Purezza:97.29%Colore e forma:SolidPeso molecolare:3428.01
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