Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(942 prodotti)
- Recettore dell'adenosina(242 prodotti)
- Recettore adrenergico(2.949 prodotti)
- Recettore della bombesina(30 prodotti)
- Recettore della bradichinina(59 prodotti)
- CXCR(149 prodotti)
- CaSR(32 prodotti)
- Recettore dei cannabinoidi(195 prodotti)
- Recettore della dopamina(410 prodotti)
- Recettore dell'endotelina(75 prodotti)
- Recettore GNRH(73 prodotti)
- GPCR19(31 prodotti)
- GRK(32 prodotti)
- GTPase(21 prodotti)
- Recettore del glucagone(166 prodotti)
- Proteina Hedgehog/Smoothened(45 prodotti)
- Recettore dell'istamina(359 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(24 prodotti)
- Recettore OX(40 prodotti)
- Recettore degli oppioidi(298 prodotti)
- PAFR(11 prodotti)
- PKA(49 prodotti)
- Recettore S1P(17 prodotti)
- SGLT(30 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 18 più sottocategorie
Trovati 5378 prodotti di "Proteina G/GPCR"
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Tiprenolol
CAS:<p>Tiprenolol is a beta adrenergic receptor antagonist.[1]</p>Formula:C13H21NO2SPurezza:99.43%Colore e forma:SolidPeso molecolare:255.38Vortioxetine hydrobromide
CAS:<p>Vortioxetine hydrobromide (Lu AA21004 hydrobromide) is a serotonin (5-HT) modulator and stimulator (SMS), inhibits 5-HT1A/1B/3A/7 receptor and SERT (IC50: 15/33</p>Formula:C18H22N2S·HBrPurezza:98.85% - 99.98%Colore e forma:SolidPeso molecolare:379.36MK-1064
CAS:<p>MK-1064 (Urokinase inhibitor 1) is a selective orexin 2 receptor antagonist (2-SORA).</p>Formula:C24H20ClN5O3Purezza:99.19% - 99.82%Colore e forma:SolidPeso molecolare:461.9Indophagolin
CAS:<p>Indophagolin: autophagy inhibitor, IC50 140 nM; blocks P2X4, P2X1, P2X3 receptors, IC50s 2.71, 2.40, 3.49 μM.</p>Formula:C19H15BrClF3N2O3SPurezza:99.76%Colore e forma:SolidPeso molecolare:523.75L-732138
CAS:<p>L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM)</p>Formula:C22H18F6N2O3Purezza:99.77%Colore e forma:SolidPeso molecolare:472.38NAN-190 hydrobromide
CAS:<p>NAN-190 hydrobromide is an antagonist of serotonin receptor 5-HT.</p>Formula:C23H28BrN3O3Purezza:95.20%Colore e forma:SolidPeso molecolare:474.39Laropiprant sodium
<p>Laropiprant sodium is a potent and selective DP receptor antagonist with Ki values of 0.57 nM for TP receptors and 2.95 nM for DP receptors.</p>Colore e forma:SolidGW842166X
CAS:<p>GW842166X: Potent CB2 agonist, EC50=63 nM, inactive at CB1, in Phase 2 trials.</p>Formula:C18H17Cl2F3N4O2Purezza:99.47%Colore e forma:SolidPeso molecolare:449.25OXA (17-33) acetate
<p>OXA (17-33) acetate is a more potent agonist of orexin-1 receptor (OX1, EC50 = 8.29 nM)) over OX2 (EC50 = 187 nM).</p>Formula:C79H125N23O22Purezza:98.52%Colore e forma:SolidPeso molecolare:1748.98MK-0557
CAS:<p>MK-0557 is a selective and orally available antagonist of the neuropeptide Y5 receptor (Ki: 1.6 nM).</p>Formula:C22H19FN4O3Purezza:99.88%Colore e forma:SolidPeso molecolare:406.41Midodrine
CAS:<p>Midodrine ((±)-Midodrin), an adrenergic alpha-1 agonist, belongs to the class of medications known as vasopressors.</p>Formula:C12H18N2O4Purezza:99.89%Colore e forma:SolidPeso molecolare:254.28Pridopidine
CAS:<p>Pridopidine (FR310826), a low-affinity D2R antagonist, enhances motor skills and has neuroprotective effects in Huntington's R6/2 mice.</p>Formula:C15H23NO2SPurezza:95.2% - 99.89%Colore e forma:SolidPeso molecolare:281.41ZM241385
CAS:<p>ZM-241385 is a high-affinity antagonist ligand selective for the adenosine A2A receptor.</p>Formula:C16H15N7O2Purezza:97.02% - 99.69%Colore e forma:SolidPeso molecolare:337.34(R)-Mirtazapine
CAS:<p>(R)-Mirtazapine ((R)-Org3770) is a 5-HT3 receptor antagonist, a potential analgesic with anti-injury perception properties.</p>Formula:C17H19N3Purezza:99.75%Colore e forma:SolidPeso molecolare:265.35Clopidogrel thiolactone
CAS:Clopidogrel thiolactone (2-oxoclopidogrel), a P2Y12 receptor inhibitor, is an antiplatelet aggregation compound.Formula:C16H16ClNO3SPurezza:98.79%Colore e forma:SolidPeso molecolare:337.82Setiptiline
CAS:Setiptiline (Org-8282) is a norepinephrine reuptake inhibitor, 2-adrenergic receptor antagonist, H1 receptor inverse agonist with antidepressant activity.Formula:C19H19NPurezza:98.05% - 98.07%Colore e forma:SolidPeso molecolare:261.36Atipamezole
CAS:Atipamezole (Antisedan) is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug.Formula:C14H16N2Purezza:99.88%Colore e forma:Off-White To Light Yellow Crystal PowderPeso molecolare:212.29Latrepirdine dihydrochloride
CAS:Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.Formula:C21H25N3·2HClPurezza:98.45%Colore e forma:SolidPeso molecolare:392.37Trabodenoson
CAS:<p>Trabodenoson (INO-8875) is a selective and potent adenosine A1 receptor agonist, an adenosine analog, for the study of primary open-angle glaucoma.</p>Formula:C15H20N6O6Purezza:99.94%Colore e forma:SolidPeso molecolare:380.36Dexpramipexole
CAS:Dexpramipexole ((R)-Pramipexole) is a mitochondrial protective agent that maintains mitochondrial function and energy production.Formula:C10H17N3SPurezza:99.78%Colore e forma:SolidPeso molecolare:211.33Rotigotine
CAS:Rotigotine (1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-) is an antiparkinson agent and dopamine receptor agonist.Formula:C19H25NOSPurezza:99.04% - 99.88%Colore e forma:SolidPeso molecolare:315.47Maropitant citrate
CAS:<p>Maropitant citrate is a synthetic neurokinin-1 receptor antagonist and substance P inhibitor, used for controlling vomiting in cats and dogs.</p>Formula:C38H50N2O9Purezza:98.91%Colore e forma:SolidPeso molecolare:678.81Protein deglycase DJ-1 against-1
CAS:<p>Protein deglycase DJ-1 against-1 penetrate the BBB and bind to DJ-1 protein,restoring neuronal cellular death in a neurotoxin MPTP-induced model of PD.</p>Formula:C24H23N3O4Purezza:97.23%Colore e forma:SolidPeso molecolare:417.46Rizatriptan
CAS:<p>Rizatriptan (Risatriptan) is a selective 5-hydroxytryptamine 1B/1D receptor agonist used in the study of migraine.</p>Formula:C15H19N5Purezza:99.74%Colore e forma:SolidPeso molecolare:269.35INCB 3284
CAS:INCB 3284, a potent human CCR2 antagonist with an IC50 of 3.7 nM, is researchable for acute liver failure and inhibits MCP-1/hCCR2 binding.Formula:C26H31F3N4O4Purezza:97.81% - 99.42%Colore e forma:SolidPeso molecolare:520.54(S)-Mirtazapine
CAS:(S)-Mirtazapine ((S)-Org3770) is a 5-HT2 receptor antagonist with pro-nociceptive effects that can be used to study depression.Formula:C17H19N3Purezza:99.37%Colore e forma:SolidPeso molecolare:265.35S-Methoprene
CAS:<p>S-Methoprene (ZR2458), a juvenile hormone analog, acts as an insecticide influencing redox activity and male sex differentiation.</p>Formula:C19H34O3Purezza:97.05% - 98.55%Colore e forma:SolidPeso molecolare:310.47GRK6-IN-2
CAS:<p>GRK6-IN-2 is a potent G protein-coupled receptor kinase 6 (GRK6) inhibitor with potential antitumor activity.GRK6-IN-2 has been studied in multiple myeloma.</p>Formula:C21H21FN6Purezza:98.94%Colore e forma:SolidPeso molecolare:376.43Rolofylline
CAS:<p>Rolofylline (KW-3902) is an adenosine A1 receptor antagonist used to study acute congestive heart failure and renal dysfunction.</p>Formula:C20H28N4O2Purezza:99.53%Colore e forma:SolidPeso molecolare:356.46Trazpiroben
CAS:Trazpiroben (TAK-906) is a selective dopamine D2/D3 receptor antagonist used in the study of gastroparesis.Formula:C31H39N3O4Purezza:99.41% - >99.99%Colore e forma:SolidPeso molecolare:517.66Fenoprofen
CAS:Fenoprofen (LILLY-5385) is a non-steroidal anti-inflammatory compound and a modifier enhancer of the melanocortin receptor, increasing ERK1/2 activation.Formula:C15H14O3Purezza:98.4%Colore e forma:SolidPeso molecolare:242.27CGP 20712 A
CAS:<p>CGP 20712 A (CGP 20712 mesylate) is a β1-adrenergic receptor antagonist with antihypertensive activity that reverses RKT-induced gastric relaxation.</p>Formula:C24H29F3N4O8SPurezza:99.37%Colore e forma:SolidPeso molecolare:590.57Fenoterol hydrobromide
CAS:Fenoterol hydrobromide is a beta2-adrenergic receptor agonist and bronchodilator used in the study of cardiovascular diseases such as asthma and bronchitis.Formula:C17H22BrNO4Purezza:99.88%Colore e forma:SolidPeso molecolare:384.27Renzapride
CAS:Renzapride (BRL 24924) is a mixed 5-hydroxytryptamine type 4 (5-HT4) agonist and 5-HT3 receptor antagonist used in the study of irritable bowel syndrome.Formula:C16H22ClN3O2Purezza:98.97% - 99.09%Colore e forma:SolidPeso molecolare:323.82CB1/2 agonist 3
CAS:<p>CB1/2 agonist 3 is a competitive and potent CB1/CB2 agonist with high affinity for hCB1 and hCB2 and can be used to study neurological disorders.</p>Formula:C25H41NO2Purezza:98.78%Colore e forma:SolidPeso molecolare:387.6Tandospirone
CAS:<p>Tandospirone (SM-3997) is a 5-HT1A receptor partial agonist with anxiolytic and antidepressant activity used in the study of central nervous system disorders.</p>Formula:C21H29N5O2Purezza:99.94%Colore e forma:SolidPeso molecolare:383.49Jatrorrhizine chloride
CAS:<p>Jatrorrhizine chloride (Neprotine chloride) is an alkaloid isolated from Rhizoma coptidis with neuroprotective, antimicrobial, and antiplasmodial activities.</p>Formula:C20H20ClNO4Purezza:99.79%Colore e forma:SolidPeso molecolare:373.8Canagliflozin hemihydrate
CAS:<p>Canagliflozin hemihydrate (TA 7284) treats type 2 diabetes by blocking SGLT2, leading to glucose excretion in urine.</p>Formula:C48H52F2O11S2Purezza:99.42% - 99.96%Colore e forma:SolidPeso molecolare:907.05WIN 51,708
CAS:WIN 51,708 is an antagonist of neurokinin-1 receptor.Formula:C29H33N3OPurezza:99%Colore e forma:SolidPeso molecolare:439.59Pentoxyverine
CAS:Pentoxyverine (Carbetapentan) is an orally available cough suppressant, an antagonist of muscarinic receptor M1 and an agonist of the σ1 receptor.Formula:C20H31NO3Purezza:97.11%Colore e forma:SolidPeso molecolare:333.47BMS-986278
CAS:<p>BMS-986278 is an orally active and potent hemophosphatidic acid receptor 1 (LPA1) antagonist with Kb values of 6.9 nM and 4.0 nM for human and mouse LPA1,</p>Formula:C22H31N5O5Purezza:99.86%Colore e forma:SolidPeso molecolare:445.51SID 7969543
CAS:<p>SID 7969543 is a selective SF-1 inhibitor with potential anticancer activity, inhibits SF-1-triggered luciferase expression and can be used for cancer research.</p>Formula:C24H24N2O7Purezza:98.94%Colore e forma:SolidPeso molecolare:452.46Ozanimod hydrochloride
CAS:Ozanimod (RPC-1063) HCl is a selective S1P1/S1P5 modulator with high affinity, used in relapsing MS research.Formula:C23H25ClN4O3Purezza:99.81%Colore e forma:SolidPeso molecolare:440.92Levocetirizine Dihydrochloride
CAS:<p>Levocetirizine Dihydrochloride is a third-gen antihistamine targeting H1-receptors, treating allergies and urticaria.</p>Formula:C21H27Cl3N2O3Purezza:99.89%Colore e forma:White Or Off-White Crystalline PowderPeso molecolare:461.81WAY-100635 maleate
CAS:<p>WAY-100635 Maleate is a specific and effective 5-HT receptor antagonist (IC50=0.95 nM).</p>Formula:C25H34N4O2·xC4H4O4Purezza:>99.99%Colore e forma:White SolidPeso molecolare:538.645CP-105696
CAS:<p>CP-105696 is a potent and selective leukotriene B4 (LTB4) receptor antagonist for the study of allograft rejection.</p>Formula:C28H28O4Purezza:99.78%Colore e forma:SolidPeso molecolare:428.52ACT-462206
CAS:ACT-462206 is a Orexin 1/Orexin 2 receptor antagonist.ACT-462206 is highly potent and can be used to study sleep and anxiety.Formula:C20H24N2O4SPurezza:99.45%Colore e forma:SolidPeso molecolare:388.48Medetomidine
CAS:<p>Medetomidine (MPV785 free base) is a selective α2-adrenoceptor agonist, with sedative and analgesic and vasoconstrictive hypoxic , in small animal anesthesia.</p>Formula:C13H16N2Purezza:99.88%Colore e forma:SolidPeso molecolare:200.28GAT211
CAS:<p>GAT211 (AZ-4) is a cannabinoid 1 receptor (CB1R) positive allosteric modulator (PAM) for the study of epilepsy.</p>Formula:C22H18N2O2Purezza:99.7%Colore e forma:SolidPeso molecolare:342.39AF-710B
CAS:<p>AF710B is an enantiomer of AF710. AF-710B is also a sigma and M1 muscarinic receptors agonist.</p>Formula:C20H27N3OSPurezza:98.62% - 99.89%Colore e forma:SolidPeso molecolare:357.51
