Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(1.037 prodotti)
- Recettore dell'adenosina(214 prodotti)
- Recettore adrenergico(3.159 prodotti)
- Recettore della bombesina(35 prodotti)
- Recettore della bradichinina(63 prodotti)
- CXCR(165 prodotti)
- CaSR(31 prodotti)
- Recettore dei cannabinoidi(223 prodotti)
- Colecistochinina(1 prodotti)
- Recettore della dopamina(447 prodotti)
- Recettore dell'endotelina(85 prodotti)
- Recettore GNRH(88 prodotti)
- GPCR19(38 prodotti)
- GRK(40 prodotti)
- GTPase(24 prodotti)
- Recettore del glucagone(204 prodotti)
- Proteina Hedgehog/Smoothened(49 prodotti)
- Recettore dell'istamina(390 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(26 prodotti)
- Recettore OX(54 prodotti)
- Recettore degli oppioidi(334 prodotti)
- PAFR(12 prodotti)
- PKA(57 prodotti)
- Recettore S1P(18 prodotti)
- SGLT(32 prodotti)
- Recettore Sigma(48 prodotti)
Mostrare 19 più sottocategorie
Trovati 5938 prodotti per "Proteina G/GPCR".
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Alprenolol
CAS:Alprenolol (Alpheprol) is a non-selective β-adrenergic receptor (β-AR) antagonist that is also an antagonist of the serotonin (5-HT) receptor subtypes 5-HT1AFormula:C15H23NO2Purezza:99.72% - 99.73%Colore e forma:SolidPeso molecolare:249.35Cericlamine
CAS:Cericlamine is a selective 5-hydroxytryptamine (5-HT) reuptake blocker with antidepressant activity.Formula:C12H17Cl2NOPurezza:99.06%Colore e forma:SolidPeso molecolare:262.18Carteolol hydrochloride
CAS:Carteolol hydrochloride is a nonselective beta-blocker used to treat hypertension, arrhythmias, angina, and glaucoma.Formula:C16H24N2O3·HClPurezza:99.84% - 99.91%Colore e forma:SolidPeso molecolare:328.83Ref: TM-T1282
10mg34,00€25mg50,00€1mL*10mM (DMSO)52,00€50mg74,00€100mg105,00€200mg157,00€500mg254,00€TSHR antagonist S37
CAS:TSHR antagonist S37 is a selective and competitive antagonist of the thyrotropin receptor (TSHR).Formula:C25H20N2O3S2Purezza:98.35%Colore e forma:SolidPeso molecolare:460.57Ref: TM-T13216
1mg64,00€2mg92,00€5mg130,00€1mL*10mM (DMSO)172,00€10mg200,00€25mg371,00€50mg553,00€100mg788,00€500mg1.603,00€AM095 free acid
CAS:AM095 (free acid) is a potent LPA1 receptor antagonist (IC50s: 0.98 and 0.73 μM for recombinant human or mouse LPA1).Formula:C27H24N2O5Purezza:99.88%Colore e forma:SolidPeso molecolare:456.49Ref: TM-T10293
1mg34,00€5mg63,00€1mL*10mM (DMSO)70,00€10mg92,00€25mg170,00€50mg268,00€100mg416,00€200mg625,00€Nafetolol
CAS:Nafetolol (K 5407) is a biochemical reagent that can be used to synthesize other compounds.Formula:C19H29NO3Purezza:98.91%Colore e forma:SolidPeso molecolare:319.44Adenosine A1 receptor activator T62
CAS:Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and alsoFormula:C15H14ClNOSPurezza:97.83%Colore e forma:SolidPeso molecolare:291.8Ref: TM-T14127
1mg64,00€5mg126,00€10mg180,00€1mL*10mM (DMSO)187,00€25mg290,00€50mg396,00€100mg537,00€200mg712,00€AVN 322 free base
CAS:AVN 322 free base is an orally available, selective and potent 5-HT6R antagonist for the study of neuropathic system disorders such as Alzheimer's disease (AD) and schizophrenia.Formula:C17H19N5O2SPurezza:99.24%Colore e forma:Yellow SolidPeso molecolare:357.43Fenoterol
CAS:Fenoterol is an agonist of β2-adrenergic receptor It is classed as sympathomimetic beta agonist and asthma medication.Formula:C17H21NO4Purezza:98.29% - 99.36%Colore e forma:Black SolidPeso molecolare:303.35Retatrutide
CAS:Retatrutide (LY3437943) is a triple agonist of GCGR, GIPR and GLP-1R that can be used to study obesity.Formula:C221H342N46O68Purezza:98.31%Colore e forma:White SolidPeso molecolare:4732.09SBI-477
CAS:SBI-477 deactivates MondoA, inhibits TAG synthesis, and boosts glucose uptake in human muscle cells.Formula:C24H25N3O6SPurezza:99.3%Colore e forma:SolidPeso molecolare:483.54Ref: TM-T12853
1mg144,00€5mg358,00€1mL*10mM (DMSO)379,00€10mg530,00€25mg850,00€50mg1.153,00€100mg1.558,00€500mg3.115,00€[Leu15]-Gastrin I, human
CAS:[Leu15]-Gastrin I, human is a variant of Gastrin I, modulating the binding of cholecystokinin to mucosal membranes.Formula:C98H126N20O31Purezza:98.02% - 98.84%Colore e forma:White SolidPeso molecolare:2080.16Mirabegron
CAS:Mirabegron (YM178) is a beta-3 adrenergic agonist that is used for treatment of overactive bladder syndrome.Formula:C21H24N4O2SPurezza:99.64%Colore e forma:SolidPeso molecolare:396.51Desvenlafaxine
CAS:Desvenlafaxine, a venlafaxine metabolite, is an SNRI used as an antidepressant.Formula:C16H25NO2Purezza:99.46% - 99.81%Colore e forma:White Crystalline PowderPeso molecolare:263.38Ciproquazone
CAS:Ciproquazone has analgesic activity and is used to treat spondylitis.Formula:C19H18N2O2Purezza:99.66%Colore e forma:SolidPeso molecolare:306.36L-741626
CAS:L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) is a selective antagonist of D2 dopamine receptor (Ki: 2.4, 100, and 220 nM for human D2, D3Formula:C20H21ClN2OPurezza:98.57%Colore e forma:SolidPeso molecolare:340.85Tetrabenazine
CAS:Tetrabenazine (Ro 1-9569) is a drug formerly used as an antipsychotic and treatment of various movement disorders.Formula:C19H27NO3Purezza:98% - 99.91%Colore e forma:SolidPeso molecolare:317.42Domperidone
CAS:Domperidone (R33812)(Motilium) is a dopamine blocker and an antidopaminergic reagent.Formula:C22H24ClN5O2Purezza:98% - 99.82%Colore e forma:SolidPeso molecolare:425.91Nicergoline
CAS:Nicergoline (Nicergolinum) is an ergot derivative used to treat senile dementia and other disorders with vascular origins.Formula:C24H26BrN3O3Purezza:98% - 99.80%Colore e forma:White SolidPeso molecolare:484.39Abarelix
CAS:Abarelix (PPI 149) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, which is used for prostate cancer treatment.Formula:C72H95ClN14O14Purezza:>99.99%Colore e forma:SolidPeso molecolare:1416.06Procaine hydrochloride
CAS:Procaine HCl is a benzoic acid derivative used as a local anesthetic, blocking nerve impulses and sensation.Formula:C13H20N2O2·HClPurezza:99.1% - 99.22%Colore e forma:SolidPeso molecolare:272.77Cinnarizine
CAS:Cinnarizine is a piperazine, blocks H1-receptor & Ca-channels, has vasodilating & antiemetic effects, may cause Parkinson-like symptoms.Formula:C26H28N2Purezza:99.94% - 99.94%Colore e forma:White SolidPeso molecolare:368.51J-113863
CAS:J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM).Formula:C30H37Cl2IN2O2Purezza:95.11%Colore e forma:SolidPeso molecolare:655.44Ref: TM-T11699
1mg56,00€2mg82,00€5mg119,00€10mg160,00€1mL*10mM (DMSO)170,00€25mg288,00€50mg500,00€100mg718,00€MK-0812 Succinate
CAS:MK-0812 Succinate is an effective and selective CCR2 antagonist.Formula:C28H40F3N3O7Purezza:98.62% - 99.93%Colore e forma:SolidPeso molecolare:587.63Ramelteon
CAS:Ramelteon (TAK-375) is a Melatonin Receptor Agonist. The mechanism of action of ramelteon is as a Melatonin Receptor Agonist.Formula:C16H21NO2Purezza:97.21% - 99.92%Colore e forma:SolidPeso molecolare:259.34Ref: TM-T1463
2mg42,00€5mg62,00€1mL*10mM (DMSO)67,00€10mg84,00€25mg129,00€50mg192,00€100mg309,00€500mg485,00€Tabernanthalog fumarate
CAS:Tabernanthalog fumarate is a 5-HT2A agonist that promotes neuronal growth and reduces alcohol consumption in mice, producing antidepressant-like effects.Formula:C18H22N2O5Purezza:99.83%Colore e forma:SoildPeso molecolare:346.38Eletriptan hydrobromide
CAS:Eletriptan hydrobromide (Eletriptan HBr) is an orally active agonist with specific affinity for the 5-hydroxytriptamine1B/1D receptor.Formula:C22H27BrN2O2SPurezza:99.69% - 99.85%Colore e forma:SolidPeso molecolare:463.43Ref: TM-T0216
2mg37,00€5mg54,00€1mL*10mM (DMSO)59,00€10mg66,00€25mg127,00€50mg205,00€100mg341,00€200mg504,00€Sertraline hydrochloride
CAS:Sertraline hydrochloride (Sertraline HCl) is a selective serotonin uptake inhibitor that is used in the treatment of depression.Formula:C17H18Cl3NPurezza:99.12% - 99.99%Colore e forma:White SolidPeso molecolare:342.69Ref: TM-T0482
5mg49,00€1mL*10mM (DMSO)54,00€10mg59,00€25mg98,00€50mg170,00€100mg222,00€200mg289,00€500mg487,00€Itopride hydrochloride
CAS:Itopride hydrochloride (Ganaton) is an AChE and D2DR inhibitor.Formula:C20H27ClN2O4Purezza:99.59%Colore e forma:SolidPeso molecolare:394.9Paliperidone
CAS:Paliperidone (9-hydroxyrisperidone)(Invega) is used as an atypical antipsychotic.Formula:C23H27FN4O3Purezza:95% - 99.08%Colore e forma:White SolidPeso molecolare:426.48Prasugrel
CAS:Prasugrel (CS-747) is a piperazine derivative and PLATELET AGGREGATION INHIBITOR that is used to prevent THROMBOSIS in patients with ACUTE CORONARY SYNDROME;Formula:C20H20FNO3SPurezza:99.62% - 99.82%Colore e forma:SolidPeso molecolare:373.44Vapreotide acetate
CAS:Vapreotide acetate (BMY-41606 acetate) is an antagonist of the neurokinin-1 (NK1) receptor (IC50: 330 nM).Formula:C59H74N12O11S2Purezza:99.67%Colore e forma:White SolidPeso molecolare:1191.42U 67827E
CAS:U 67827E is a long-lasting cholecystokinin agonist. It acts by decreases food intake.Formula:C53H68N10O17SPurezza:98%Colore e forma:SolidPeso molecolare:1149.24Enuvaptan
CAS:Enuvaptan is a vasopressin receptor antagonist and has the potential for research into renal and cardiovascular diseases.Formula:C21H15ClF6N8O3Colore e forma:SolidPeso molecolare:576.84AA 497 HCl
CAS:AA 497, a beta-2 agonist, suppresses Ca spikes.Formula:C14H22ClNO3Colore e forma:SolidPeso molecolare:287.78PAMP-12 (unmodified) (TFA)
PAMP-12 (unmodified) TFA, an endogenous peptide and potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM), induces hypotension by inhibiting catecholamine secretionFormula:C79H119F3N24O17Colore e forma:SolidPeso molecolare:1733.94Peptide YY (PYY) (3-36), porcine TFA
Peptide YY (PYY) (3-36), porcine TFA, functions as a gut hormone that serves as a Y2 receptor agonist, effectively reducing appetite [1].Formula:C176H272N52O54·C2HF3O2Colore e forma:SolidPeso molecolare:4094.44APTAA-LHRH
CAS:APTAA-LHRH is a gonadorelin antagonist.Formula:C69H91Cl2N17O14Purezza:98%Colore e forma:SolidPeso molecolare:1453.475-hydroxy Propranolol
CAS:5-hydroxy Propranolol, a propranolol metabolite, is formed in the liver via P450 2D6.Formula:C16H21NO3Colore e forma:SolidPeso molecolare:275.348[Ala2] Endothelin-3, human
CAS:[Ala2] Endothelin-3, a linear ET-3 analog with Ala replacing Cys, stimulates endothelial cell migration.Formula:C120H166N26O32S4Colore e forma:SolidPeso molecolare:2613.02Neuropeptide W-30 (rat)
CAS:Neuropeptide W-30 (rat) acts as a crucial stress mediator within the central nervous system, influencing the hypothalamus-pituitary-adrenal (HPA) axis and sympathetic outflow. It serves as an endogenous ligand for the two related orphan G-protein-coupled receptors (GPCRs), GPR7 and GPR8. NPW-30 binds and activates both GPR7 and GPR8 at comparable effective doses [1] [2] [3].Formula:C165H249N49O38SColore e forma:SolidPeso molecolare:3559.11PG-931 TFA
PG-931 TFA, a potent MC4 receptor agonist (IC50 0.58 nM), excels in selectivity and helps reverse hemorrhagic shock in vivo.Formula:C61H86F3N15O13Colore e forma:SolidPeso molecolare:1294.42GRPP (human)
CAS:GRPP (human), a 30-amino-acid peptide derived from Gcg, modestly elevates plasma insulin levels while reducing plasma glucagon concentrations.Formula:C136H215N41O58SColore e forma:SolidPeso molecolare:3384.47MLGFFQQPKPR-NH2
CAS:MLGFFQQPKPR-NH2 is a reversed Substance P peptide. Substance P is a neuropeptide [1] .Formula:C63H98N18O13SColore e forma:SolidPeso molecolare:1347.63OXA(17-33) TFA
OXA(17-33) TFA: Potent OX1 agonist, ~23x more selective for OX1 (EC50=8.29nM) than OX2 (187nM).Formula:C81H126F3N23O24Colore e forma:SolidPeso molecolare:1863Anticancer agent 258
CAS:Anticanceragent 258 is an imidazo[1,2-B][1,2,4]triazole derivative that modulates nuclear receptor activity. It exhibits an EC50 of 63 nM for Nurr in N2A cells and an IC50 of 0.1 pM for Nur77 in HEK293 cells. Anticanceragent 258 is applicable in studies related to cancer, metabolic disorders, and neurological diseases.Formula:C17H12F2N4Colore e forma:SolidPeso molecolare:310.3Alprostadil ethyl ester
CAS:Alprostadil ethyl ester is a biochemical used in the treatment of scleroderma.Formula:C22H38O5Colore e forma:SolidPeso molecolare:382.53Spantide I TFA
Spantide I TFA is a selective NK1 antagonist (230 nM); much less for NK2 (8150 nM); it modulates cytokines to prevent corneal perforation.Formula:C77H109F3N20O15Colore e forma:SolidPeso molecolare:1611.81ANQ-11125 TFA
ANQ-11125 TFA is a motilin antagonist with a pKd of 8.24, inhibiting motilide contractions in rabbits.Formula:C88H126F3N19O23Colore e forma:SolidPeso molecolare:1875.05NPS ALX Compound 4a hydrochloride(1:1)
NPS ALX Compound 4a hydrochloride(1:1) is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM.Formula:C25H26ClN3O2SPurezza:99.84%Colore e forma:Yellow SolidPeso molecolare:468.01Ref: TM-T12262L1
1mg38,00€5mg84,00€1mL*10mM (DMSO)92,00€10mg113,00€25mg188,00€50mg273,00€100mg371,00€200mg494,00€
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