Proteina G/GPCR
Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.
Sottocategorie di "Proteina G/GPCR"
- recettore 5-HT(1.025 prodotti)
- Recettore dell'adenosina(251 prodotti)
- Recettore adrenergico(3.027 prodotti)
- Recettore della bombesina(35 prodotti)
- Recettore della bradichinina(61 prodotti)
- CXCR(158 prodotti)
- CaSR(34 prodotti)
- Recettore dei cannabinoidi(218 prodotti)
- Colecistochinina(1 prodotti)
- Recettore della dopamina(445 prodotti)
- Recettore dell'endotelina(86 prodotti)
- Recettore GNRH(84 prodotti)
- GPCR19(36 prodotti)
- GRK(33 prodotti)
- GTPase(23 prodotti)
- Recettore del glucagone(195 prodotti)
- Proteina Hedgehog/Smoothened(49 prodotti)
- Recettore dell'istamina(385 prodotti)
- Recettore LPA(21 prodotti)
- Recettore della melatonina(26 prodotti)
- Recettore OX(41 prodotti)
- Recettore degli oppioidi(327 prodotti)
- PAFR(14 prodotti)
- PKA(60 prodotti)
- Recettore S1P(18 prodotti)
- SGLT(31 prodotti)
- Recettore Sigma(46 prodotti)
Mostrare 19 più sottocategorie
Trovati 6011 prodotti di "Proteina G/GPCR"
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TG6-129
CAS:TG6-129 is an EP2 receptor antagonist, blocking PGE2 effects, reducing inflammatory markers with 1.6 µM IC50.Formula:C20H18FN5O3S3Purezza:99.55%Colore e forma:SolidPeso molecolare:491.58Ref: TM-T28958
1mg114,00€5mg227,00€1mL*10mM (DMSO)321,00€10mg404,00€25mg665,00€50mg888,00€100mg1.251,00€500mg2.538,00€ZINC49534341
CAS:ZINC49534341 is a potent MRGPRX2 antagonist, exhibiting a K_i (inhibition constant) of 32 nM [1].Formula:C12H9N3OS2Colore e forma:SolidPeso molecolare:275.35FTY720 (S)-Phosphate
CAS:FTY720 (S)-Phosphate is an active FTY720 derivative modulating S1P receptors, preventing lymphocyte egress, enhancing barrier integrity, aiding immune research.Formula:C19H34NO5PPurezza:99.37%Colore e forma:SolidPeso molecolare:387.45RS100329 hydrochloride
CAS:RS 100329 hydrochloride is an antagonist of α1A-adrenergic receptor.Formula:C20H26ClF3N4O3Purezza:99.95%Colore e forma:SolidPeso molecolare:462.89Ref: TM-T23253
500mgPrezzo su richiesta1mg34,00€5mg60,00€10mg99,00€25mg208,00€50mg310,00€100mg444,00€5-HT3 antagonist 1
CAS:5-HT3 antagonist 1 is a potent and selective antagonist of 5-HT3 receptor.Formula:C22H27N5OPurezza:98%Colore e forma:SolidPeso molecolare:377.48Vatinoxan hydrochloride
CAS:Vatinoxan hydrochloride is an antagonist of the peripheral α2 adrenergic receptors.Formula:C20H27ClN4O4SPurezza:98%Colore e forma:SolidPeso molecolare:454.97LGD-6972 sodium
CAS:LGD-6972 sodium is a glucagon receptor antagonist.Formula:C43H46N2NaO5SPurezza:98%Colore e forma:SolidPeso molecolare:725.915(R)-15-methyl Prostaglandin F2α
CAS:15(R)-15-methyl PGF2α, a metabolically stable analog of PGF2α, is an inactive, prodrug PGF agonist intended for activation by gastric acid through oral administration. This transformation involves acid-catalyzed epimerization that converts 15(R)-15-methyl PGF2α into its active counterpart, the 15(S)-isomer. Upon conversion, the 15(S)-isomer has been shown to induce luteolysis in rhesus monkeys following an approximately 12 mg/animal dosage, a response not observed with the 15(R)-isomer.Formula:C21H36O5Colore e forma:SolidPeso molecolare:368.514AJ-76 hydrochloride
CAS:AJ-76 hydrochloride ((+)-AJ 76 hydrochloride) serves as a dopamine autoreceptor antagonist, exhibiting pK i values of 6.95 for hD3, 6.67 for hD4, 6.37 for hD2S, 6.21 for hD2L, and 6.07 for rD2 receptors, indicating its binding affinity strength across these receptor types.Formula:C15H24ClNOColore e forma:SolidPeso molecolare:269.815-HT2A receptor agonist-3
CAS:5-HT2A receptor agonist-3 represents the highest selectivity for the human 5-HT2A receptor currently identified, exhibiting a K i of 2.5 nM.Formula:C21H26BrNO3Purezza:98%Colore e forma:SolidPeso molecolare:420.34Δ17-6-keto Prostaglandin F1α
CAS:Δ17-6-keto Prostaglandin F1α (Δ17-6-keto PGF1α), a cyclooxygenase (COX) metabolite produced from eicosapentaenoic acid (EPA) in a variety of tissues including seminal vesicles, lungs, polymorphonuclear leukocytes, and ocular tissues, alongside other 3-series COX products from EPA such as PGF3α, PGE3, and thromboxane B3, is potentially linked to a lower occurrence of glaucoma in individuals consuming a marine-rich (EPA-rich) diet.Formula:C20H32O6Colore e forma:SolidPeso molecolare:368.47CB1 antagonist 1
CAS:CB1 antagonist 1 is a CB1 receptor antagonist, used in the research of obesity and metabolic syndrome, neuroinflammatory disorders, cognitive disorders, andFormula:C26H22Cl2N4Purezza:98%Colore e forma:SolidPeso molecolare:461.39SORT-PGRN interaction inhibitor 2
CAS:SORT-PGRN Interaction Inhibitor 2 is a compound that downregulates SORT1 protein expression and enhances extracellular progranulin (PGRN) secretion in variousFormula:C19H31NOColore e forma:SolidPeso molecolare:289.46O-Arachidonoyl glycidol
CAS:O-Arachidonoyl glycidol (compound 1), a 2-arachidonoylglycerol (2-AG) analog, effectively inhibits the hydrolysis of cytosolic 2-oleoylglycerol (2-OG) with an IC50 value of 4.5 µM, and also blocks 2-OG and anandamide hydrolysis in membrane fractions with IC50 values of 19 µM and 12 µM, respectively [1].Formula:C23H36O3Colore e forma:SolidPeso molecolare:360.53Desethoxy Quetiapine hydrochloride
CAS:Desethoxy quetiapine, an active metabolite of the atypical antipsychotic quetiapine, primarily forms through the action of the cytochrome P450 (CYP) isoform CYP3A5. This compound binds to dopamine D2 receptors with an IC50 value of 1,330 nM. In vivo, desethoxy quetiapine at dosages of 20 and 40 mg/kg mitigates dopamine receptor agonist apomorphine-induced climbing behavior and ameliorates swimming deficits in mice, showcasing its potential modulatory effects on dopamine-mediated behaviors.Formula:C19H21N3OSHClColore e forma:SolidPeso molecolare:412.38(-)-Isoproterenol hydrochloride
CAS:(-)-Isoproterenol hydrochloride is used as a β-adrenergic receptor agonist in the treatment of bradycardia and as a bronchodilator.Formula:C11H17NO3·CIHColore e forma:SolidPeso molecolare:247.72GSK2263167
CAS:GSK2263167 is an agonist of S1P1 receptor.Formula:C25H26N4O4Colore e forma:SolidPeso molecolare:446.5CCG-63802
CAS:CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins.Formula:C26H18N4O2SPurezza:90%Colore e forma:SolidPeso molecolare:450.51CP 154,526
CAS:CP 154,526 is a selective CRF1 receptor antagonist (Ki = 2.7 nM). CP 154,526 blocks CRF-induced activation of adenylate cyclase and the HPA axis.Formula:C23H32N4Colore e forma:SolidPeso molecolare:364.53(R)-Monlunabant
CAS:(R)-Monlunabant ((R)-MRI-1891) serves as a CB1 receptor antagonist utilized in obesity and metabolic disease research [1].Formula:C26H22ClF3N6O3SPurezza:98%Colore e forma:SolidPeso molecolare:591
