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Proteina G/GPCR

Proteina G/GPCR

Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.

Sottocategorie di "Proteina G/GPCR"

Mostrare 19 più sottocategorie

Trovati 5838 prodotti di "Proteina G/GPCR"

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  • VCH-286
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    VCH-286

    CAS:
    VCH-286 is a C-C chemokine receptor type 5 (CCR5) receptor antagonist.
    Formula:C34H50F2N4O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:600.78

    Ref: TM-T29100

  • UWA-101 hydrochloride
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    UWA-101 hydrochloride

    CAS:
    <p>UWA-101 hydrochloride is a selective, non-cytotoxic inhibitor of DAT/SERT, demonstrating EC50 values of 3.6 µM for DAT and 2.3 µM for SERT inhibition. It mitigates motor disorders and other side effects associated with dopaminergic agent use (e.g., L-DOPA) without exhibiting psychotropic effects. This compound is utilized in research focused on neurodegenerative conditions like Parkinson's disease [1] [2].</p>
    Formula:C13H18ClNO2
    Colore e forma:Solid
    Peso molecolare:255.74

    Ref: TM-T84399

  • Dihydrexidine
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    Dihydrexidine

    CAS:
    <p>Dihydrexidine is a full efficacy D1-like dopamine receptor (D1/D5) agonist (IC50: 10 nM for D1 receptor). It also shows potent antiparkinsonian activity.</p>
    Formula:C17H17NO2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:267.32

    Ref: TM-T13463L

  • Logo CymitQuimica
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    BIM-23056 TFA

    CAS:
    BIM 23056 TFA, a potent linear octapeptide antagonist of sst3 and sst5 somatostatin receptors, exhibits inhibition constants (K_i) of 10.8 for sst3 and 5.7 for
    Formula:C73H82F3N11O11
    Colore e forma:Solid
    Peso molecolare:1346.49

    Ref: TM-T75844

  • Thromboxane A2
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    Thromboxane A2

    CAS:
    Thromboxane A2: unstable, leads to thromboxane B2, induces platelet aggregation, causes vasoconstriction.
    Formula:C20H32O5
    Colore e forma:Solid
    Peso molecolare:352.47

    Ref: TM-T34862

  • 4-hydroxy Nebivolol hydrochloride
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    4-hydroxy Nebivolol hydrochloride

    CAS:
    <p>4-Hydroxy Nebivolol, a primary metabolite of Nebivolol, results from the enzymatic hydroxylation of Nebivolol by the cytochrome P450 (CYP) isoform CYP2D6.</p>
    Formula:C22H25F2NO5HCl
    Colore e forma:Solid
    Peso molecolare:457.9

    Ref: TM-T85245

  • Tarazepide
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    Tarazepide

    CAS:
    Tarazepide is a potent and specific antagonist of CCK-A receptor.
    Formula:C28H24N4O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:448.52

    Ref: TM-T13084

  • RXFP1 receptor agonist-5
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    RXFP1 receptor agonist-5

    CAS:
    RXFP1 receptor agonist-5 (Example 98) is an agonist that targets the RXFP1 receptor and demonstrates its bioactivity by inhibiting cAMP production in HEK293
    Formula:C30H23F6N3O7
    Colore e forma:Solid
    Peso molecolare:651.51

    Ref: TM-T81242

  • AGN-191129
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    AGN-191129

    CAS:
    AGN-191129 (PGF2α-OMe) is a PGF2α analog with C-1 carboxyl replaced by O-methyl; it lowers eye pressure, but its receptors are unclear.
    Formula:C21H38O4
    Colore e forma:Solid
    Peso molecolare:354.52

    Ref: TM-T29725

  • L 743310
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    L 743310

    CAS:
    L 743310 is an antagonist of the neurokinin-1 receptor.
    Formula:C30H33BrF6N4O2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:675.5

    Ref: TM-T24359

  • S1P5 receptor agonist-1
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    S1P5 receptor agonist-1

    CAS:
    S1P5 Receptor Agonist-1 (example 6) is a highly potent and selective agonist for the S1P5 receptor, exhibiting an EC50 value of 20 nM.
    Formula:C20H24F3NO3
    Colore e forma:Solid
    Peso molecolare:383.4

    Ref: TM-T72294

  • PD-140548
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    PD-140548

    CAS:
    PD-140548 is a potent, CCKA receptor-selective antagonist.
    Formula:C33H39N3O5
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:557.68

    Ref: TM-T28341

  • iso-TRAP-6
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    iso-TRAP-6

    CAS:
    <p>iso-TRAP-6 (iso-SFLLRN), a hexapeptide made from isoserine instead of serine, is a PAR1 agonist that activates platelets via PAR-1.</p>
    Formula:C34H56N10O9
    Purezza:98.55%
    Colore e forma:Solid
    Peso molecolare:748.87

    Ref: TM-T78099

  • trans-J-113863
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    trans-J-113863

    CAS:
    <p>Trans-J-113863 serves as a potent antagonist of chemokine receptors CCR1 and CCR3, effectively inhibiting MIP-1α-induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants, with respective half-maximal inhibitory concentrations (IC50) of 9.57 nM and 93.8 nM [1] [2].</p>
    Formula:C30H37Cl2IN2O2
    Colore e forma:Solid
    Peso molecolare:655.44

    Ref: TM-T84888

  • Logo CymitQuimica
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    Obestatin(rat) TFA

    CAS:
    <p>Obestatin(rat) TFA, a 23-amino-acid peptide, modulates appetite, gut motility, and body weight; binds GPR39; has anti-inflammatory and antioxidant effects.</p>
    Formula:C116H175F3N34O33
    Colore e forma:Solid
    Peso molecolare:2630.83

    Ref: TM-T75901

  • Logo CymitQuimica
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    [D-Ala6]-LH-RH

    CAS:
    [D-Ala6]-LH-RH, a Luteinizing-hormone-releasing hormone (LHRH) analogue, functions as a gonadotropin-releasing hormone (GnRH) receptor agonist [1].
    Formula:C56H77N17O13
    Colore e forma:Solid
    Peso molecolare:1196.32

    Ref: TM-T76351

  • LY-426965
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    LY-426965

    CAS:
    LY-426965 is a selective, potent, orally bioavailable 5-HT1A antagonist.
    Formula:C28H38N2O2
    Colore e forma:Solid
    Peso molecolare:434.61

    Ref: TM-T27955

  • LMD-009
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    LMD-009

    CAS:
    LMD-009 is a non-peptide, selective CCR8 agonist that mediates chemotaxis, inositol phosphate accumulation, and calcium release, with an EC50 of 11–87 nM.
    Formula:C29H33N3O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:471.59

    Ref: TM-T11862

  • PZ-1190
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    PZ-1190

    CAS:
    <p>PZ-1190, a multitarget ligand for serotonin and dopamine receptors, exhibits potential antipsychotic activity in rodents [1].</p>
    Formula:C27H30N4O2S2
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:506.68

    Ref: TM-T81336

  • BAY 73-1449
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    BAY 73-1449

    CAS:
    BAY 73-1449 is a selective and potent antagonist of the prostacyclin receptor(IC50<0.1 nM).
    Formula:C26H23N3O3
    Purezza:99.77%
    Colore e forma:Solid
    Peso molecolare:425.48

    Ref: TM-T26745