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Proteina G/GPCR

Proteina G/GPCR

Gli inibitori dei GPCR/proteine G sono composti che bersagliano i recettori accoppiati alle proteine G (GPCR) e le proteine G associate, che svolgono ruoli critici nella trasmissione dei segnali dall'esterno all'interno delle cellule. Questi inibitori sono essenziali per studiare le vie di segnalazione mediate dai GPCR, coinvolte in numerosi processi fisiologici, tra cui la percezione sensoriale, la risposta immunitaria e la neurotrasmissione. Gli inibitori dei GPCR sono anche importanti nello sviluppo di farmaci, poiché molti agenti terapeutici prendono di mira questi recettori. Presso CymitQuimica, offriamo una vasta gamma di inibitori dei GPCR/proteine G di alta qualità per supportare le tue ricerche in farmacologia, biologia cellulare e campi correlati.

Sottocategorie di "Proteina G/GPCR"

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Trovati 5378 prodotti di "Proteina G/GPCR"

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  • L-796778 acetate
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    L-796778 acetate

    CAS:
    <p>L-796778 acetate is a selective sst3 receptor agonist. In CHO-K1 cells expressing hsst3 receptors, it acts as a partial agonist that inhibits Forskolin-induced cAMP production, with an IC50 value of 18 nM. Additionally, L-796778 acetate exhibits anticonvulsant properties.</p>
    Formula:C31H44N6O9
    Colore e forma:Solid
    Peso molecolare:644.716

    Ref: TM-T206311

  • Ici D1542
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    Ici D1542

    CAS:
    Ici D1542: potent TXS inhibitor & TXA2 receptor antagonist, effective thromboxane blocker in vitro.
    Formula:C25H30N2O7
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:470.51

    Ref: TM-T24157

  • Logo CymitQuimica
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    LP 12 hydrochloride hydrate

    <p>LP 12 hydrochloride hydrate: potent, selective 5-HT7 agonist (Ki: 0.13 nM); less affinity for D2, 5-HT1A/2A receptors.</p>
    Formula:C32H39N3O·HCl·xH2O
    Colore e forma:Solid

    Ref: TM-T64269

  • Henagliflozin
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    Henagliflozin

    CAS:
    <p>Henagliflozin (SHR3824): an oral, selective SGLT2 inhibitor, weak on SGLT1.</p>
    Formula:C22H24ClFO7
    Colore e forma:Solid
    Peso molecolare:454.87

    Ref: TM-T32058

  • NCATS-SM4420
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    NCATS-SM4420

    CAS:
    <p>NCATS-SM4420 (Compound A35) is an orally effective ligand for the thyroid-stimulating hormone receptor (TSHR) that inhibits the proliferation of MDA-T32 and MDA-T85 cells both in vitro and in vivo, with IC50 values of 0.71 μM and 0.38 μM, respectively. Additionally, it suppresses the metastasis of MDA-T85F1 in mice. NCATS-SM4420 holds potential for research in the field of thyroid cancer.</p>
    Formula:C31H27N3O5
    Colore e forma:Solid
    Peso molecolare:521.56

    Ref: TM-T200723

  • GHSR-1a agonist-1
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    GHSR-1a agonist-1

    CAS:
    <p>GHSR-1a agonist-1 (Compound 4b) is an orally active agonist of the human growth hormone secretagogue receptor 1a (GHSR-1a) with an EC50 of 0.49 nM. It effectively stimulates the release of endogenous growth hormone by activating GHSR-1a. Doses as low as 0.1 mg/kg (administered orally) can increase body weight and length in 4-week-old rats. GHSR-1a agonist-1 is applicable in research on pediatric growth and developmental delays.</p>
    Formula:C30H37N5O4
    Colore e forma:Solid
    Peso molecolare:531.646

    Ref: TM-T206698

  • SCH-900822
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    SCH-900822

    CAS:
    <p>SCH-900822 is a potent and selective glucagon receptor antagonist.</p>
    Formula:C34H43Cl2N7O2
    Colore e forma:Solid
    Peso molecolare:652.66

    Ref: TM-T71201

  • Revexepride
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    Revexepride

    CAS:
    <p>Revexepride, a 5-HT4 agonist, may boost CYP3A4, used for treating GERD.</p>
    Formula:C21H32ClN3O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:425.95

    Ref: TM-T16737

  • Logo CymitQuimica
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    Protease-Activated Receptor-1 antagonist 2

    <p>Selective, orally active PAR-1 antagonist with an IC50 of 7 nM, potential for cardiovascular disease studies.</p>
    Colore e forma:Solid

    Ref: TM-T64285

  • CCR7 Ligand 1
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    CCR7 Ligand 1

    CAS:
    <p>CCR7-Cmp2105 is a thiadiazole-dioxide allosteric antagonist for CCR7 with a Kd of 3 nM and IC50 of 7.3 μM against arrestin binding.</p>
    Formula:C22H29N5O5S
    Colore e forma:Solid
    Peso molecolare:475.56

    Ref: TM-T10716

  • CI-988
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    CI-988

    CAS:
    <p>CCK2 (CCK-B) receptor antagonist</p>
    Formula:C35H42N4O6
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:614.73

    Ref: TM-T22666

  • SSR-241586
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    SSR-241586

    CAS:
    <p>SSR-241586: Neurokinin antagonist, treats depression, schizophrenia, urinary issues, emesis, IBS.</p>
    Formula:C32H42Cl2N4O3
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:601.61

    Ref: TM-T13002

  • Mesulergine hydrochloride
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    Mesulergine hydrochloride

    CAS:
    <p>5-HT2A and 2C receptor antagonist</p>
    Formula:C18H27ClN4O2S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:398.95

    Ref: TM-T22970

  • ADORA2A/PDE4D-IN-1
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    ADORA2A/PDE4D-IN-1

    CAS:
    <p>ADORA2A/PDE4D-IN-1 (Compound 9) is a dual inhibitor of the adenosine A2a receptor (ADORA2A) and phosphodiesterase 4D (PDE4D). This compound is applicable for research in bronchial asthma.</p>
    Formula:C14H11N5
    Colore e forma:Solid
    Peso molecolare:249.271

    Ref: TM-T204528

  • Logo CymitQuimica
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    S1P1 agonist 5

    <p>Selective oral S1P1 agonist 5 inhibits lymphocyte drainage, potential for MS research.</p>
    Formula:C23H24ClN2NaO4
    Colore e forma:Solid
    Peso molecolare:450.89

    Ref: TM-T62732

  • Logo CymitQuimica
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    5-HT1A antagonist 1

    <p>Compound 6f is a potent, selective 5-HT1A receptor blocker (Ki: 35 nM), useful in CNS disorder research.</p>
    Formula:C23H29ClN6O2
    Colore e forma:Solid
    Peso molecolare:456.97

    Ref: TM-T62843

  • Bometolol Hydrochloride
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    Bometolol Hydrochloride

    CAS:
    <p>Bometolol Hydrochloride is a beta-adrenergic blocking compound used for the treatment of cardiovascular disease.</p>
    Formula:C25H33ClN2O7
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:508.99

    Ref: TM-T13585

  • (Rac)-BI 703704
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    (Rac)-BI 703704

    CAS:
    <p>(Rac)-BI 703704 is a potent activator of soluble guanylyl cyclase (sGC).</p>
    Formula:C32H37N3O4S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:559.72

    Ref: TM-T12661

  • GPR27 agonist-1
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    GPR27 agonist-1

    CAS:
    <p>GPR27 agonist-1 (compound I) is a selective agonist for GPR27 with a pEC50 value of 6.34.</p>
    Formula:C19H14Cl2N2O3S
    Colore e forma:Solid
    Peso molecolare:421.30

    Ref: TM-T201309

  • CVT-5440
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    CVT-5440

    CAS:
    <p>CVT-5440 is a selective, high-affinity (2B) adenosine receptor antagonist with good selectivity.</p>
    Formula:C27H28N6O5
    Colore e forma:Solid
    Peso molecolare:516.55

    Ref: TM-T31122