Nucleosidi e Nucleotidi
I nucleosidi sono composti formati da una base azotata legata a uno zucchero (ribosio o desossiribosio). Quando un gruppo fosfato viene aggiunto al nucleoside, si forma un nucleotide. Questi composti sono fondamentali nella biologia cellulare, poiché i nucleotidi sono i mattoni essenziali del DNA e dell’RNA, responsabili dell’archiviazione e della trasmissione delle informazioni genetiche. I nucleosidi trovano applicazione nel trattamento delle malattie virali, agendo come inibitori della replicazione virale. I nucleotidi, oltre al loro ruolo strutturale negli acidi nucleici, sono coinvolti nei processi energetici, come la sintesi dell’ATP.
Presso CymitQuimica, offriamo un’ampia gamma di nucleosidi e nucleotidi essenziali per la ricerca in biologia molecolare, virologia e farmacologia.
Trovati 3421 prodotti di "Nucleosidi e Nucleotidi"
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5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-F-2472
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-A-2830
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaLY-404187
CAS:<p>LY404187 is a positive allosteric modulator of AMPA receptors</p>Formula:C19H22N2O2SPurezza:99.34%Colore e forma:SolidPeso molecolare:342.46VAS2870
CAS:<p>VAS2870 is an inhibitor of NADPH oxidase (NOX).</p>Formula:C18H12N6OSPurezza:99.74%Colore e forma:SolidPeso molecolare:360.39Ref: 4Z-R-0444
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaNitrobenzylthioinosine
CAS:<p>Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.</p>Formula:C17H17N5O6SPurezza:99.69% - 99.74%Colore e forma:Off-White SolidPeso molecolare:419.41Bictegravir
CAS:<p>Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase (IC50: 7.5 nM).</p>Formula:C21H18F3N3O5Purezza:97.6% - 99.51%Colore e forma:SolidPeso molecolare:449.38Cladribine
CAS:<p>Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.</p>Formula:C10H12ClN5O3Purezza:99.58% - >99.99%Colore e forma:White Crystalline SolidPeso molecolare:285.69CNQX disodium
CAS:<p>CNQX disodium is a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures.</p>Formula:C9H2N4Na2O4Purezza:97.77%Colore e forma:SolidPeso molecolare:276.12Desciclovir
CAS:<p>Desciclovir (DCV), a prodrug of the antiherpetic agent acyclovir (ACV), is converted in humans to ACV, presumably by xanthine oxidase.</p>Formula:C8H11N5O2Purezza:99.54%Colore e forma:SolidPeso molecolare:209.21Enprofylline
CAS:<p>Enprofylline (Enprofilina), a bronchodilator, acts primarily as a competitive nonselective phosphodiesterase inhibitor.</p>Formula:C8H10N4O2Purezza:98.37%Colore e forma:SolidPeso molecolare:194.19Nelarabine
CAS:<p>Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.</p>Formula:C11H15N5O5Purezza:98.10% - 99.6%Colore e forma:White SolidPeso molecolare:297.27Ref: 4Z-R-0422
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaDeoxycytidine triphosphate trisodium salt
CAS:<p>Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) contributes to antibiotic lethality in stationary-phase mycobacteria.</p>Formula:C9H13N3Na3O13P3Purezza:99.80%Colore e forma:SolidPeso molecolare:533.1Azvudine
CAS:<p>Azvudine (FNC) is a powerful NRTI effective against HIV, HBV, HCV, and resistant strains.</p>Formula:C9H11FN6O4Purezza:99.76% - >99.99%Colore e forma:SolidPeso molecolare:286.22Diquafosol tetrasodium
CAS:<p>Diquafosol Tetrasodium is a P2Y2 receptor agonist that stimulates the secretion of mucins from ocular tissues Diquafosol tetrasodium (INS365) improves tear film</p>Formula:C18H22N4Na4O23P4Purezza:98.25% - 99.97%Colore e forma:SolidPeso molecolare:878.23Deoxycytidine triphosphate
CAS:<p>dCTP is a nucleotide used in DNA synthesis, PCR, cDNA creation, and sequencing.</p>Formula:C9H16N3O13P3Purezza:99.68%Colore e forma:SolidPeso molecolare:467.16Creatine
CAS:<p>Creatine, an amino acid in vertebrates, forms phosphocreatine in muscle, aids energy transfer, is made in the liver, and mainly stored in muscles.</p>Formula:C4H9N3O2Purezza:99.63% - 99.83%Colore e forma:Colourless To Light Yellow SolidPeso molecolare:131.13Adenosine 5'-diphosphate
CAS:<p>Adenosine 5'-diphosphate (ADP) is a natural nucleotide derived from the dephosphorylation of ATP. ADP induces platelet aggregation. Cost effective and quality assured.</p>Formula:C10H15N5O10P2Purezza:99.5% - >99.99%Colore e forma:SolidPeso molecolare:427.2Lamivudine
CAS:<p>Lamivudine (BCH-189) is a reverse transcriptase inhibitor and ZALCITABINE analog in which a sulfur atom replaces the 3' carbon of the pentose ring.</p>Formula:C8H11N3O3SPurezza:99.56% - >99.99%Colore e forma:White Crystalline PowderPeso molecolare:229.26Melamine
CAS:<p>Melamine is used for making resin, and forms in mammals after eating cyromazine.</p>Formula:C3H6N6Purezza:99.49%Colore e forma:White Solid PowderPeso molecolare:126.12Ref: 4Z-S-055089
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaUridine triphosphate trisodium salt
CAS:<p>Uridine triphosphate trisodium salt (UTP, Trisodium Salt) is a nucleotide.</p>Formula:C9H12N2Na3O15P3Purezza:99.82% - 99.83%Colore e forma:White PowderPeso molecolare:550.09Ref: 4Z-V-0138
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaATP
CAS:<p>ATP (Adenosine triphosphate) provides cellular energy, participates in overall energy balance, and maintains intracellular homeostasis.</p>Formula:C10H16N5O13P3Purezza:98% - >99.99%Colore e forma:SolidPeso molecolare:507.18Ref: 4Z-L-383
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-P-124075
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaAdefovir
CAS:<p>Adefovir: acyclic nucleoside phosphonate, reverse transcriptase inhibitor for hepatitis B and herpes treatment.</p>Formula:C8H12N5O4PPurezza:99.56%Colore e forma:White To Off-White PowderPeso molecolare:273.19Ref: 4Z-F-2465
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaCabotegravir
CAS:<p>Cabotegravir (S/GSK1265744) (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (</p>Formula:C19H17F2N3O5Purezza:98.55% - 99.92%Colore e forma:SolidPeso molecolare:405.352-Aminopurine
CAS:<p>2-Aminopurine is a double-stranded RNA-dependent protein kinase, protein kinase R (PKR) inhibitor.</p>Formula:C5H5N5Purezza:99.51%Colore e forma:White To Light Yellow Crystal PowderPeso molecolare:135.13Ref: 4Z-A-267018
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaCaroverine hydrochloride
CAS:<p>Caroverine HCL: Blocks NMDA/AMPA receptors, antioxidant, calcium-blocker, and vasorelaxant, used for tinnitus research.</p>Formula:C22H28ClN3O2Purezza:98.37% - 98.75%Colore e forma:SolidPeso molecolare:401.9Cidofovir
CAS:<p>Cidofovir ((S)-HPMPC) 通过特异性抑制病毒 DNA 合成来抑制病毒复制。</p>Formula:C8H14N3O6PPurezza:99.24% - 99.76%Colore e forma:Fluffy White PowderPeso molecolare:279.19CX516
CAS:<p>CX516 (Ampalex), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, schizophrenia and MCI.</p>Formula:C14H15N3OPurezza:99.04% - ≥95%Colore e forma:Tan SolidPeso molecolare:241.29S29434
CAS:<p>S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).</p>Formula:C21H18N4O3Purezza:99.92%Colore e forma:SolidPeso molecolare:374.39Inosine
CAS:<p>Inosine (NSC-20262), an endogenous purine nucleoside produced by the catabolism of adenosine, is an agonist of adenosine receptors A1R and A2AR. Low-Cost!</p>Formula:C10H12N4O5Purezza:99.51% - 99.89%Colore e forma:SolidPeso molecolare:268.23Peramivir Trihydrate
CAS:<p>Peramivir Trihydrate (RWJ-270201) is a neuraminidase inhibitor (IC50: 0.09 nM) which prevents normal processing of virus particles such that virus particles are</p>Formula:C15H28N4O4·3H2OPurezza:99.52% - ≥95%Colore e forma:SolidPeso molecolare:382.45Dapagliflozin
CAS:<p>Dapagliflozin (BMS-512148) is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.</p>Formula:C21H25ClO6Purezza:99.5% - 99.93%Colore e forma:SolidPeso molecolare:408.87cangrelor tetrasodium
CAS:<p>Cangrelor tetrasodium is a reversible and selective antagonist of platelet P2Y12, with prompt and potent antiplatelet effects.</p>Formula:C17H21Cl2F3N5Na4O12P3S2Purezza:98.51% - 98.6%Colore e forma:SolidPeso molecolare:864.29Etravirine
CAS:<p>Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor.</p>Formula:C20H15BrN6OPurezza:97.61% - 99.74%Colore e forma:White To Off-White SolidPeso molecolare:435.28IDRA-21
CAS:IDRA-21 is a positive AMPA receptor modulator.Formula:C8H9ClN2O2SPurezza:99.73%Colore e forma:SolidPeso molecolare:232.69Levomefolate calcium
CAS:<p>Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.</p>Formula:C20H23CaN7O6Purezza:97.35%Colore e forma:Off-White To Pale Yellow SolidPeso molecolare:497.52Dexelvucitabine
CAS:<p>Dexelvucitabine (RVT), a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Formula:C9H10FN3O3Purezza:98.25%Colore e forma:SolidPeso molecolare:227.19Cidofovir dihydrate
CAS:<p>Cidofovir dihydrate: Injectable anti-CMV; suppresses CMV by inhibiting viral DNA polymerase; treats CMV retinitis in AIDS.</p>Formula:C8H18N3O8PPurezza:99.44%Colore e forma:SolidPeso molecolare:315.22Fludarabine Phosphate
CAS:<p>Fludarabine Phosphate (NSC 312887 Phosphate) is a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine with antineoplastic activity.</p>Formula:C10H13FN5O7PPurezza:99.25% - 99.78%Colore e forma:SolidPeso molecolare:365.21Hibifolin
CAS:<p>Hibifolin is a flavonol glycoside natural product,is a potential inhibitor of adenosine deaminase (Ki of 49.92 μM).</p>Formula:C21H18O14Purezza:98.92%Colore e forma:SolidPeso molecolare:494.361,5-Isoquinolinediol
CAS:<p>1,5-Isoquinolinediol, a PARP1 inhibitor (IC50: 0.39 μM), is used in DNA repair and cell death studies.</p>Formula:C9H7NO2Purezza:98.29% - 99.35%Colore e forma:Of White To White PowderPeso molecolare:161.16Dilazep dihydrochloride
CAS:<p>Dilazep dihydrochloride inhibits adenosine uptake, ischemia, nucleoside transport, platelet aggregation, and acts as a vasodilator.</p>Formula:C31H46Cl2N2O10Purezza:98.39%Colore e forma:SolidPeso molecolare:677.61Remdesivir
CAS:<p>Remdesivir (GS-5734) is a nucleoside analog, a broad-spectrum antiviral compound that exerts its activity by inhibiting the RNA-dependent RNA polymerase of</p>Formula:C27H35N6O8PPurezza:97.62% - 99.98%Colore e forma:SolidPeso molecolare:602.58Uridine
CAS:<p>Uridine (Uridin) is a nucleoside compound, a base that makes up RNA, that replaces thymine in DNA during transcriptione. Cost-effective and quality-assured.</p>Formula:C9H12N2O6Purezza:99.08% - 99.82%Colore e forma:White To Off-White Crystalline PowderPeso molecolare:244.2Adenosine monophosphate
CAS:<p>AMP is a purine nucleotide, vital in cell signaling and energy regulation, and inhibits EC 3.1.3.11 and 3.1.3.1, also an A1 receptor agonist.</p>Formula:C10H14N5O7PPurezza:99.59% - 99.84%Colore e forma:Crystals From Water + Acetone SolidPeso molecolare:347.22GKT136901
CAS:<p>GKT136901 (AK120765) is an inhibitor of NOX1/4.It acts as Selective and Direct Scavenger of Peroxynitrite</p>Formula:C19H15ClN4O2Purezza:99.16%Colore e forma:SolidPeso molecolare:366.8Ref: 4Z-E-2225
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaNADPH tetrasodium salt
CAS:<p>NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of</p>Formula:C21H26N7Na4O17P3Purezza:97.15% - >99.99%Colore e forma:SolidPeso molecolare:833.35NADPH tetracyclohexanamine
CAS:<p>NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.</p>Formula:C45H82N11O17P3Purezza:98.73% - 99.05%Colore e forma:SolidPeso molecolare:1142.12Thiamine pyrophosphate chloride
CAS:<p>Thiamine pyrophosphate, a vitamin B1 derivative, is a coenzyme in transketolase studies for decarboxylation in biology.</p>Formula:C12H19ClN4O7P2SPurezza:98.29% - 99.72%Colore e forma:SolidPeso molecolare:460.76ASP-9521
CAS:<p>ASP-9521 is a selective, potent and orally active indole-based AKR1C3 inhibitor with an IC50 of 11 nM for human AKR1C3.Cost-effective and quality-assured.</p>Formula:C19H26N2O3Purezza:95.11% - 96.96%Colore e forma:SolidPeso molecolare:330.42Rabeprazole sodium
CAS:<p>Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.</p>Formula:C18H20N3NaO3SPurezza:98% - 99.912%Colore e forma:White Or Off White Crystalline PowderPeso molecolare:381.42Ganciclovir sodium
CAS:<p>Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.</p>Formula:C9H13N5NaO4Purezza:99.93%Colore e forma:SolidPeso molecolare:278.22Didanosine
CAS:<p>Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).</p>Formula:C10H12N4O3Purezza:99.64%Colore e forma:White Crystalline PowderPeso molecolare:236.23Cytosine
CAS:<p>Cytosine is a pyrimidine nucleic acid base; its deamination can cause mutations in leukemia and cancer.</p>Formula:C4H5N3OPurezza:99.67%Colore e forma:SolidPeso molecolare:111.1Sofosbuvir
CAS:<p>Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatment</p>Formula:C22H29FN3O9PPurezza:99.77% - 99.82%Colore e forma:SolidPeso molecolare:529.45Cytidine 5'-monophosphate
CAS:<p>Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide, one of the basic units that make up RNA.</p>Formula:C9H14N3O8PPurezza:98.78% - 99.10%Colore e forma:SolidPeso molecolare:323.20Ref: 4Z-A-8178
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-C-161002
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaN2-Nitroso Folinic Acid (N2-Nitroso (6RS)-Calcium Levofolinate EP Impurity H, N2-Nitroso Leucovorin)
Formula:C20H22N8O8Peso molecolare:502.44Ref: 4Z-F-068042
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-A-267064
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-B-167028
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-B-167030
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-B-167027
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-D-62168
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaRef: 4Z-B-167029
5mgPrezzo su richiesta10mgPrezzo su richiesta25mgPrezzo su richiesta50mgPrezzo su richiesta100mgPrezzo su richiestaDapagliflozin Tetraacetate
CAS:<p>Applications Dapagliflozin Tetraacetate is a derivative of Dapagliflozin [D226255], a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011); Bernhardson, D. et al.: Org. Proc. Res. Dev., 18, 57 (2014);<br></p>Formula:C29H33ClO10Colore e forma:WhitePeso molecolare:577.02N-Carbamoyl-2-fluoro-(β)-alanine
CAS:Prodotto controllato<p>Applications A metabolite of Capecitabine.<br>References Arellano, M., ET AL.: Br. J. Cancer, 77, 79 (1998), Budman, D., ET AL.: J. Clin. Oncol., 16, 1795 (1998), Khanna, R., et al.: Cancer Res., 60, 4725 (2000), Charasson, V., et al.: Drug Metab. Dispos., 30, 731 (2002),<br></p>Formula:C4H7FN2O3Colore e forma:NeatPeso molecolare:150.11Viaminate
CAS:Prodotto controllato<p>Applications Viaminate is a pharmaceutical used to treat severe acne and other keratinization disorders. Viaminate can be taken orally, or topically in prepared gels and creams.<br>References Zhang, H.; et al.: Am. J. Med. Sci., 356, 84 (2018); Lu, J.; et al.: Zhongguo Yaofang, 22, 155 (2011); Li, G.: Zhonghua Yiyao Zazhi, 7, 536 (2007).<br></p>Formula:C29H37NO3Colore e forma:Light YellowPeso molecolare:447.615-Methyl-2’-deoxy Cytidine
CAS:<p>Applications A Cytidine (C998300) analog and also an isostere of Thymidine (T412000).<br>References Sabini, E., et al.: J. Med. Chem., 51, 4219 (2008), Sabini, E., et al.: J. Mol. Biol., 378, 607 (2008),<br></p>Formula:C10H15N3O4Colore e forma:NeatPeso molecolare:241.243’-Amino-3’-deoxythymidine
CAS:Prodotto controllato<p>Impurity Zidovudine Impurity;<br>Stability Hygroscopic, Moisture Sensitive<br>Applications A metabolite of Zidovudine (3'-Azido-3'-deoxythymidine; AZT).<br>References Qian, M., et al.: Biochem. Pharmacol., 48, 383 (1994), Diwan, B., et al.: Toxicol. Appl. Pharmacol., 161, 82 (1999) , Lim, S., et al.: J. Biol. Chem., 276, 23616 (2001), Von Tungeln, L., et al.: Carcinogenesis, 23, 1427 (2002),<br></p>Formula:C10H15N3O4Colore e forma:White To Off-WhitePeso molecolare:241.24Entecavir-13C2,15N
CAS:Prodotto controllato<p>Applications Labelled Entecavir. An oral antiviral drug used in the treatment of hepatitis B infection. A guanine analogue that inhhibits all three steps in the viral replication process.<br>References Innaimo, S.F., et al.: Antimicrob. Agents Chemother., 41, 1444 (1997), Honkoop, P., et al.: Expert Opin. Invest. Drugs, 12, 683 (2003), Chang, T.-T., et al.: N. Engl. J. Med., 354, 1001 (2006),<br></p>Formula:C1013C2H15N415NO3Colore e forma:White To Off-WhitePeso molecolare:280.264’-Epi Lamivudine
CAS:Prodotto controllato<p>Applications Lamivudine epimer.<br>References Chang, C., et al.: J. Biol. Chem., 267, 13938 (1992), Jeong, L., et al.: J. Med. Chem., 36, 181 (1993),<br></p>Formula:C8H11N3O3SColore e forma:NeatPeso molecolare:229.26RO 2433
CAS:Prodotto controllato<p>Impurity Sofosbuvir Metabolite GS331007<br>Applications RO 2433 is the deaminated metabolite of β-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine, an effective inhibitor of hepatitis C virus (HCV) replication in vitro.<br>References Asif, G., et. al.: Antimicrob. Agents Ch., 51, 2877 (2007)<br></p>Formula:C10H13FN2O5Colore e forma:NeatPeso molecolare:260.223’,5’-Di-O-benzyl Entecavir
CAS:Prodotto controllato<p>Applications 3’,5’-Di-O-benzyl Entecavir is an intermediate in the preparation of the hepatitis B antiviral agent, Entecavir (E558900).<br>References Li, R. et al.: Zhong. Yao., 6, 292 (2008); Bisacchi, G.S. et al.: Bioorg. Med. Chem. Lett., 7, 127 (1997);<br></p>Formula:C26H27N5O3Colore e forma:NeatPeso molecolare:457.52cis 5-Fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2,4(1H,3H)- pyrimidinedione
CAS:Prodotto controllato<p>Applications Antiviral nucleoside analog, also an impurity found in emtricitabine (E525000).<br>References Jeong, L., et al.: J. Med. Chem., 36, 181 (1993),<br></p>Formula:C8H9FN2O4SColore e forma:Off-WhitePeso molecolare:248.23Favipiravir
CAS:Prodotto controllato<p>Applications Favipiravir is used for the treatment of advanced Ebola virus infection in a small animal model. Favipiravir suppressed the replication of Zaire Ebola virus and prevented a lethal outcome in 100% of the animals. Based on the studies, Favipiravir can be a candidate for the treatment of Ebola hemorrhagic fever. It is a COVID19-related research product.<br>References Oestereich, L., et al.: Antiviral Res., 105, 17 (2014); Baranovich, T., et al.: J. Virol. 87, 3741 (2013); Chem. and Eng. News p.8, Dec. 1 (2014)<br></p>Formula:C5H4FN3O2Colore e forma:NeatPeso molecolare:157.10Folic Acid-13C5
CAS:<p>Applications A vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate.<br>References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010), Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010), McKay, D., et al.: Nut. J., 9 (2010),<br></p>Formula:C5C14H19N7O6Colore e forma:Dark Yellow To Dark BrownPeso molecolare:446.362-Oxa-1,4-butanediol diacetate
CAS:Prodotto controllatoFormula:C7H12O5Colore e forma:NeatPeso molecolare:176.17trans-Abacavir Dihydrochloride
CAS:Prodotto controllato<p>Applications trans-Abacavir Dihydrochloride is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.<br>References (1) Jackson, A., et al.: Antivir Ther. 17, 19 (2012) (2) Yuen, G. J., et al.: Clin Pharmacokinet. 47, 351 (2008)<br></p>Formula:C14H18N6O·2HClColore e forma:NeatPeso molecolare:359.25Adenosine 5’-Monophosphoramidate Sodium Salt
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Used in the characterization and elucidation of coordination requirements of adenine nucleotides complexes with Fe(II) ions.<br>References Richter, Y., et al.: Nucleos. Nucleot. Nucleic Acids, 22, 1757 (2003),<br></p>Formula:C10H14N6O6P·NaColore e forma:NeatPeso molecolare:368.22O-Benzoyllamivudine
CAS:Prodotto controllatoFormula:C15H15N3O4SColore e forma:Off-WhitePeso molecolare:333.362Folinic acid
CAS:<p>Folinic acid (Leucovorin) is a biofolic acid that can be used in the treatment of methotrexate, often in combination with Methotrexate (MTX) to reduce MTX-</p>Formula:C20H23N7O7Purezza:99.76%Colore e forma:Crystals From Water With 3 Mol Of Water Of Crystallization SolidPeso molecolare:473.44N2-Acetyl Acyclovir
CAS:Prodotto controllato<p>Impurity Aciclovir EP Impurity F<br>Applications N2-Acetyl Acyclovir (Aciclovir EP Impurity F) is an impurity of Acyclovir (A192400).<br>References Balon, K., et al.: Pharm. Res., 16, 882 (1999),<br></p>Formula:C10H13N5O4Colore e forma:BeigePeso molecolare:267.245-Fluoro ent-Lamivudine Acid D-Menthol Ester
CAS:Prodotto controllato<p>Applications Intermediate in the synthesis of ent-Emtricitabine (E525005).<br></p>Formula:C18H26FN3O4SColore e forma:NeatPeso molecolare:399.486-Deoxypenciclovir
CAS:Prodotto controllato<p>Applications A metabolite of Famciclovir, an antiviral.<br>References Harnden, M.R., et al.: J. Med. Chem., 32, 1738 (1989)<br></p>Formula:C10H15N5O2Colore e forma:Off White SolidPeso molecolare:237.261R-Dapagliflozin
CAS:Prodotto controllato<p>Applications 1R-Dapagliflozin is an isomer of Dapagliflozin (D185370), which is a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Formula:C21H25ClO6Colore e forma:NeatPeso molecolare:408.883'-Deoxyinosine
CAS:Prodotto controllato<p>Impurity Didanosine EP Impurity D<br>Applications 3'-Deoxyinosine (Didanosine EP Impurity D) is an Inosine (I661000) analog with potential use as an antileishmanial drug. Used as an inhibiting agent in studies of Trypanosoma cruzi growth inside host cells in vitro. An impurity of the antiviral drug 2’,3’-Dideoxyinosine (D440950).<br>References Morishige, K. et al.: Exp. Parasitol., 80, 665 (1995); Aoki, T. et al.: Adv. Exp. Med. Biol., 370, 499 (1994);<br></p>Formula:C10H12N4O4Colore e forma:NeatPeso molecolare:252.23α-Decitabine
CAS:Prodotto controllato<p>Applications α-Decitabine is shown to inhibit DNA methylation resulting in an effective anticancer agent.<br>References Hajek, M. et al.: Biochem. Pharm., 75, 965 (2008); Rogstad, D. et al.: Chem. Res. Toxicol., 22, 1194 (2009);<br></p>Formula:C8H12N4O4Colore e forma:NeatPeso molecolare:228.21Capecitabine-d11
CAS:Prodotto controllatoFormula:C152H11H11FN3O6Colore e forma:NeatPeso molecolare:370.422,4-Diamino-6-hydroxypyrimidine
CAS:Prodotto controllato<p>Applications 2,4-Diamino-6-hydroxypyrimidine (cas# 56-06-4) is a compound useful in organic synthesis.<br></p>Formula:C4H6N4OColore e forma:NeatPeso molecolare:126.12Abacavir-d4
CAS:Prodotto controllato<p>Stability Very Hygroscopic<br>Applications Abacavir-d4 is deuterium labeled Abacavir (A104990). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.<br>References (1) Jackson, A., et al.: Antivir Ther. 17, 19 (2012) (2) Yuen, G. J., et al.: Clin Pharmacokinet. 47, 351 (2008)<br></p>Formula:C14H14D4N6OColore e forma:Off-WhitePeso molecolare:290.361’-epi-Cladribine
CAS:<p>Applications 1’-epi-Cladribine is an impurity of Cladribine (C557500), a substituted purine nucleoside with antileukemic activity.<br>References Seto, S., et al.: J. Clin. Invest., 75, 377 (1985), Piro, L.D., et al.: N. Engl. J. Med., 322, 1117 (1990),<br></p>Formula:C10H12ClN5O3Colore e forma:NeatPeso molecolare:285.69Barbituric Acid
CAS:<p>Impurity Fluorouracil EP Impurity A<br>Applications Barbituric Acid (Fluorouracil EP Impurity A) is a parent compound of barbiturate drugs. Unsubstituted barbituric acid has no hypnotic properties.<br>References Luo, Y., et al.: J. Med. Chem., 53, 3846 (2010), Tomasic, T., et al.: Eur. J. Med. Chem., 45, 1667 (2010), Gilbert, A., et al.: Bioorg. Med. Chem. Lett., 20, 636 (2010),<br></p>Formula:C4H4N2O3Colore e forma:NeatPeso molecolare:128.09Floxuridine-13C,15N2
CAS:Prodotto controllato<p>Applications Labelled Floxuridine. Antiviral; antineoplastic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harris, M., et al.: Biophys. J., 4, 203 (1964),<br></p>Formula:C813CH11F15N2O5Colore e forma:WhitePeso molecolare:249.17Melamine-15N3
CAS:<p>Applications Isotope labelled Melamine (M208703), which forms synthetic resins with formaldehyde. It remains largely non-metabolized in male Wistar rats with 90% of the administered dose excreted in the urine (1,2) and thus acts as a non-protein nitrogen food additive found in milk (3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Mast, R. et al.: Food Chem Toxicol. 1983 Dec;21(6):807-10.2. Smith, J. et al.: Toxicol Appl Pharmacol. 1994 Apr;125(2):296-308.3. Anirudhan, T. et al.: Food Chem. 2017 Jul 15;227:85-92.<br></p>Formula:C3H615N3N3Colore e forma:White To Off-WhitePeso molecolare:129.10Dapagliflozin hydroxy Impurity (Mixture of Diastereomers)
CAS:<p>Applications (1S)-1,5-anhydro-1-C-[4-Chloro-3-[(4-ethoxyphenyl)hydroxymethyl]phenyl]-D-glucitol is an impurity of the drug Dapagliflozin (D185370), a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Formula:C21H25ClO7Colore e forma:White To Off-WhitePeso molecolare:424.872Laninamivir
CAS:<p>Applications A new potent neuraminidase (NA) inhibitor, shows long-acting anti-influenza virus activity.<br>References Bantia, S., et al.: Antimicrob. Agents Chemother., 42, 801 (1998), Honda, T., et al.: Bioorg. Med. Chem. Lett., 12, 1925 (2002), Kiso, M., et al.: Lancet, 364, 759 (2004), Macdonald, S., et al.: J. Med. Chem., 48, 2964 (2005),<br></p>Formula:C13H22N4O7Colore e forma:White To Off-WhitePeso molecolare:346.34Zanamivir
CAS:Prodotto controllato<p>Applications Influenza viral neuraminidase inhibitor; structural analog of the sialic acid. Antiviral.<br>References Woods, J.M., et al.: Antimicrob. Agents Chemother., 37, 1473 (1993), Pegg, M.S., et al.: Biochem. Mol. Biol. Int., 32, 851 (1994), Monto, A.S., et al.: J. Am. Med. Assoc., 282, 31 (1999),<br></p>Formula:C12H20N4O7Colore e forma:NeatPeso molecolare:332.31Entecavir
CAS:<p>Applications An oral antiviral drug used in the treatment of hepatitis B infection. A guanine analogue that inhhibits all three steps in the viral replication process.<br>References Innaimo, S.F., et al.: Antimicrob. Agents Chemother., 41, 1444 (1997), Honkoop, P., et al.: Expert Opin. Invest. Drugs, 12, 683 (2003), Chang, T.-T., et al.: N. Engl. J. Med., 354, 1001 (2006),<br></p>Formula:C12H15N5O3Colore e forma:NeatPeso molecolare:277.28Adenosine-3’,5’-cyclic Monophosphate
CAS:<p>Stability Hygroscopic<br>Applications Adenosine-3’,5’-cyclic Monophosphate is an Adenosine (A280400) derivative useful as anticancer agent.<br>References Keast, R., et al.: Pharma. Res., 19, 1019 (2002),<br></p>Formula:C10H12N5O6PColore e forma:NeatPeso molecolare:329.21[1',2',3',4',5'-13C5]Uridine
CAS:Prodotto controllato<p>Applications Labelled Uridine, a nucleoside; widely distributed in nature. Uridine is one of the four basic components of ribonucleic acid (RNA)<br>References Lorine, P., et al.: J. Biol. Chem., 178, 439 (1949); Grakoui, A., et al.: J. Virol., 63, 5216 (1989); Strauss, J., et al.: Microbiol. Rev., 58, 491 (1994); Lin, Y., et al.: Virology, 292, 78 (2002);<br></p>Formula:C5C4H12N2O6Colore e forma:NeatPeso molecolare:249.16Etravirine
CAS:Prodotto controllato<p>Applications Etravirine is a novel HIV reverse transcriptase inhibitor useful in treatment of HIV infection.<br>References Scholler-Gyure, M., et al.: J. Clin. Pharmacol., 48, 322 (2008), Thakur, A., et al.: Eur. J. Med. Chem., 43, 471 (2008),<br></p>Formula:C20H15BrN6OColore e forma:White To Off-WhitePeso molecolare:435.281,3-Dioxolane (Stabilized with BHT)
CAS:Prodotto controllatoFormula:C3H6O2Colore e forma:NeatPeso molecolare:74.08Baquiloprim
CAS:<p>Stability Hygroscopic<br>Applications Baquiloprim is an amiopyrimidine antibacterial synergist with high activity and slow elimination. Baquiloprim has a better half-life than trimethoprim.<br>References Zhi-hui, H., et al.: Anhui Nongye Kexue, 41, 2503 (2013)<br></p>Formula:C17H20N6Colore e forma:Light YellowPeso molecolare:308.382’-Deoxycytidine 5'-Monophosphate Hydrate
CAS:Prodotto controllato<p>Applications A phosphorylated metabolite of the deoxyribonucleoside 2’-Deoxycytidine. A constituent of Deoxyribonucleic acid. Studies show that it increases influenza virus antigen-induced immune cell proliferation.<br>References Holen, E. et al.: Nutrition, 21, 1003 (2005); Alexandre, J.A. et al.: Nucleosides Nucleotides Nucelic Acids, 26, 1375 (2007);<br></p>Formula:C9H14N3O7P·xH2OColore e forma:White To Off-WhitePeso molecolare:307.20 + x(18.02)5-Aza Cytosine
CAS:Prodotto controllato<p>Impurity Azacitidine USP Related Compound A<br>Applications Inhibits the growth of Escherichia coli. Azacitidine USP Related Compound A.<br>References Shapir, N., et al.: J. Bacteriol., 184, 5376 (2002), Hrdlicka, P., et al.: Bioorg. Med. Chem., 13, 1249 (2005), Krecmerova, M., et al.: J. Med. Chem., 50, 1069 (2007),<br></p>Formula:C3H4N4OColore e forma:White SolidPeso molecolare:112.09Gemcitabine-13C,15N2 Hydrochloride
CAS:<p>Stability Hygroscopic<br>Applications Labelled Gemcitabine, an antineoplastic.<br>References Hertel, L.W., et al.: Cancer Res., 50, 4417 (1990), Abbruzzese, J.L., et al.: J. Clin. Oncol., 9, 491 (1991), Ruiz, V.W.T., et al.: Biochem. Pharmacol., 46, 762 (1993),<br></p>Formula:C813CH12ClF2N15N2O4Colore e forma:Off-WhitePeso molecolare:302.64D-Glucono-1,5-lactone
CAS:Prodotto controllato<p>Applications A lactone (cyclic ester) of D-gluconic acid used as a used as a sequestrant, an acidifier, or a curing, pickling, or leavening agent.<br>References Jacob, M. et al.: Food Hydrocoll., 25, 928 (2011); Li, J. et al.: J. Sci. Food Agric., 91, 38, 2011;<br></p>Formula:C6H10O6Colore e forma:NeatPeso molecolare:178.142’,2’-Difluoro-2’-deoxyuridine
CAS:Prodotto controllatoFormula:C9H10F2N2O5Colore e forma:White To Off-WhitePeso molecolare:264.184-[(2-Chloroethyl)amino]-L-phenylalanine Dihydrochloride
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications 4-[(2-Chloroethyl)amino]-L-phenylalanine is a metabolite of Melphalan (M216900); an antineoplastic.<br>References Ross, W.C.J., et al.: Biochem. Pharmacol., 13, 969 (1964); Donelli, M.G., et al.: J. Pharm. Pharmacol., 18, 760 (1966); Furner, R.L., et al.: Cancer Treat. Rep., 64, 559 (1980)<br></p>Formula:C11H15ClN2O2HClColore e forma:NeatPeso molecolare:242.702ent-Entecavir
CAS:Prodotto controllato<p>Applications ent-Entecavir is an enantiomeric impurity of the antiviral drug Entecavir (E558900).<br>References Ruediger, E. et al.: Tetrahed. Lett., 45, 739 (2004): Bisacchi, G.S. et al.: Bioorg. Med. Chem. Lett., 7, 127 (1997);<br></p>Formula:C12H15N5O3Colore e forma:NeatPeso molecolare:277.28Canagliflozin 2-Glucuronide
CAS:Prodotto controllato<p>Applications Canagliflozin 2-glucuronide is a derivative of Canagliflozin (C175190). Canagliflozin is a sodium-glucose cotransporter 2 inhibitor that is used to treat patients with type 2 diabetes. Canagliflozin lowers blood glucose by increasing the amount of glucose that exits the body through urinary excretion.<br>References Devineni, D., et al.: Diab. Obes. Metab., 14, 539 (2012); Nicolle, L., et al.: Curr. Med. Res. Opin., 28, 1167 (2012)<br></p>Formula:C30H33FO11SColore e forma:NeatPeso molecolare:620.64Penciclovir
CAS:<p>Applications An antiviral.<br>References Weinberg, A., et al.: Antimicrob. Ag. Chemother., 36, 2037 (1992), McMeekin, J.R., et al.: Anal. Proc., 29, 178 (1992),<br></p>Formula:C10H15N5O3Colore e forma:NeatPeso molecolare:253.26Dapagliflozin 3-O-β-D-Glucuronide
CAS:Prodotto controllatoFormula:C27H33ClO12Colore e forma:NeatPeso molecolare:584.9975-Fluoro Cytosine
CAS:Prodotto controllato<p>Applications 5-FC is a toxic antifungal/antimicrobial agent.<br>References Gopinath, P., et al.: Biotechnol. Lett., 30, 1913 (2008), Kalkanci, A., et al.: Microbiol Immunol., 52, 435 (2008), Dubeau, M., et al.: App. Env. Microbiol., 75, 1211 (2009),<br></p>Formula:C4H4FN3OColore e forma:White To Off-WhitePeso molecolare:129.09Ribavirin-13C2
CAS:Prodotto controllato<p>Applications Ribavirin-13C2 is the labeled analogue of Ribavirin (R414475), a purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.This compound is suitable for pyruvate dehydrogenase (PDH) related research.<br>References Fernandez, H., et al.: Eur. J. Epidemiol., 2, 1 (1986); Liao, H.J. and Stollar, V.: Antiviral Res., 22, 285 (1993); Honda, Y., et al.: Antimicrob. Agents Chemother., 38, 653 (1994); Reichard, O., et al.: Lancet, 351, 83 (1998)<br></p>Formula:C613C2H12N4O5Colore e forma:WhitePeso molecolare:246.19α-Decitabine-3',5'-bis(4-chlorobenzoate)
CAS:Prodotto controllatoFormula:C22H18Cl2N4O6Colore e forma:White To Off-WhitePeso molecolare:505.308Adenosine-13C5
CAS:<p>Stability Hygroscopic<br>Applications Labelled nucleotide.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010), Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010),<br></p>Formula:C513C5H13N5O4Colore e forma:White To Off-WhitePeso molecolare:272.20N-Des-1-β-D-ribofuranosyl Ribavirin
CAS:<p>Impurity Ribavirin EP Impurity D<br>Applications N-Des-1-β-D-ribofuranosyl Ribavirin (Ribavirin EP Impurity D) is an impurity in the synthesis of Ribavirin (R414475), a purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.This compound is suitable for pyruvate dehydrogenase (PDH) related research.<br>References Fernandez, H., et al.: Eur. J. Epidemiol., 2, 1 (1986), Liao, H.J. and Stollar, V.: Antiviral Res., 22, 285 (1993), Honda, Y., et al.: Antimicrob. Agents Chemother., 38, 653 (1994), Reichard, O., et al.: Lancet, 351, 83 (1998)<br></p>Formula:C3H4N4OColore e forma:Off White SolidPeso molecolare:112.09Decarboxylated S-Adenosylmethionine Sulfate Salt
CAS:<p>Stability Hygroscopic<br>Applications Decarboxylated S-Adenosylmethionine Sulfate Salt, is a substrate that is involved in the biosynthesis of polyamines including spermidine, spermine, and thermospermine.<br>References Takahashi,T., et al.: Ann. Bot., 105, 1 (2009); Wu, H., et al.: Biochem., 46, 8331 (2007); Pegg, A., et al.: Biochem., 28, 8446 (1989);<br></p>Formula:C14H23N6O3S•H2SO4•HSO4Colore e forma:White SolidPeso molecolare:355.4498079706Ammeline
CAS:<p>Applications Ammeline is a metabolite of Melamine (1) (M208700), which acts as a non-protein nitrogen food additive (2). Also present in pet foods as well (3).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br>References 1. Mast RW. et al.: Food Chem Toxicol. 1983 Dec;21(6):807-10.2. Ehling S. et al.: Food Addit Contam. 2007 Dec;24(12):1319-25.3. Vail T. et al.: J Anal Toxicol. 2007 Jul-Aug;31(6):304-12.<br></p>Formula:C3H5N5OColore e forma:ColourlessPeso molecolare:127.10Cabotegravir-d3
CAS:Prodotto controllatoFormula:C19H14D3F2N3O5Colore e forma:NeatPeso molecolare:408.375’-Deoxy-5-fluorocytidine-13C,15N2
CAS:Prodotto controllato<p>Applications A labelled metabolite of Capecitabine.<br></p>Formula:C813CH12FN15N2O4Colore e forma:NeatPeso molecolare:248.191-β-D-Arabinofuranosyluracil
CAS:<p>Impurity Cytarabine EP Impurity A<br>Applications Antiviral agent. Used for the treatment of severe acute respiratory syndrome (SARS).<br>References Weber, G., et al.: Cancer Res., 43, 3466 (1983), Broet, P., et al.: J. Clin. Oncol., 19, 2778 (2001), Galmarini, C., et al.: Leukemia, 15, 875 (2001), Barth, R., et al.: Cancer Res., 64, 6287 (2004), Song, M., et al.: Bioorg. Med. Chem., 12, 489 (2004),<br></p>Formula:C9H12N2O6Colore e forma:WhitePeso molecolare:244.20N-Methyltetrahydrofolic Acid
CAS:Prodotto controllato<p>Applications N-Methyltetrahydrofolic acid (cas# 134-35-0) is a useful research chemical.<br></p>Formula:C20H25N7O6Colore e forma:NeatPeso molecolare:459.46O-[(Guanin-9-yl)methyl] Acyclovir
CAS:<p>Impurity Aciclovir EP Impurity J<br>Applications O-(Guanin-9-yl)methyl Acyclovir (Aciclovir EP Impurity J) is a dimer impurity of the antiviral agent Acyclovir (A192400).<br>References Ashton, D.S. et al.: J. Chrom. A, 707, 367 (1995);<br></p>Formula:C14H16N10O4Colore e forma:BeigePeso molecolare:388.343'-Azido-3'-deoxythymidine
CAS:Prodotto controllato<p>Applications A potent and selective inhibitor of HIV-1 replication.<br>References Mitsuya, H., et al.: Nature, 325, 773 (1987), Brehm, J., et al.: Biochem., 47, 14020 (2008), Paredes, R., et al.: J. Virol., 83, 2038 (2009), Wan, J., et al.: J. Med. Chem., 52, 1144 (2009), Mainardes, R., et al.: J. Pharm. Sci., 98, 257 (2009),<br></p>Formula:C10H13N5O4Colore e forma:White To YellowPeso molecolare:267.24Biopterin-d3
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Labelled Biopterin. A pteridine widely distributed in nature; naturally occurring as the L-erythro-form. Considered as a growth factor for some insects. Fluoresces with a blue color in alkaline solution.<br>References Klatt, P., et al.: J. Biol. Chem., 269, 13861 (1994), Mitnaul, L., et al.: Biochemistry, 92, 885 (1995), Thony, B., et al.: Biochem. J., 347, 1 (2000),<br></p>Formula:C92H3H8N5O3Colore e forma:Beige To BrownPeso molecolare:240.234-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone
CAS:<p>Applications 4-Amino-5-fluoro-1-(2,3-di-O-acetyl-α-D-ribofuranosyl)-2(1H)-pyrimidinone is an impurity of Capecitabine (C175650), which is an antineoplastic agent. Capecitabine is a prodrug of Doxifluridine (D556750).<br>References Muss, H., et al.: New Eng. J. Med., 360, 2055 (2009), Takahashi, S., et al.: Drug Metab. Disposition, 37, 956 (2009), Saltz, L., et al.: J. Clin. Oncol., 27, 653 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Formula:C13H16FN3O6Colore e forma:Off White PowderPeso molecolare:329.28(-)-Inosine
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Has neuroprotective properties improving axonal wiring. Has been used to treat stroke patients to restore neural function. Neuroprotective product.<br>References Vandemeulebroucke, A., et al.: Biochem., 49, 8999 (2010), Nestor, G., et al.: J. Agric. Food Chem., 58, 10799 (2010),<br></p>Formula:C10H12N4O5Colore e forma:White To Off-WhitePeso molecolare:268.23Emtricitabine Tenofovir Monosoproxil
Prodotto controllato<p>Stability Hygrscopic<br>Applications Emtricitabine Tenofovir Monosoproxil is a derivative of Emtricitabine (E525000). Emtricitabine is a reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner.<br>References FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. InfecSchinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: . Dis., 182, 599 (2000)<br></p>Formula:C23H32FN8O10PSColore e forma:NeatPeso molecolare:662.585-Chloro-1-methyl-4-nitroimidazole
CAS:Prodotto controllato<p>Impurity Azathioprine EP Impurity C<br>Applications 5-Chloro-1-methyl-4-nitroimidazole (cas# 4897-25-0) is a compound useful in organic synthesis.<br></p>Formula:C4H4ClN3O2Colore e forma:White To Off-WhitePeso molecolare:161.551-(Diaminomethylene)-3-b-D-ribofuranosyl-urea Picrate
CAS:Prodotto controllato<p>Impurity Azacitidine USP Related Compound C<br>Stability Hygroscopic<br>Applications 1-(Diaminomethylene)-3-β-D-ribofuranosyl-urea Picrate is a related compound of Azacitidine, a DNA metnyltransferase (DNMT) inhibitor for treating myelodysplastic syndromes (MDS).<br>References Rajendiran, C., et al.: PCT Int. Appl. WO 2012135405 A1 20121004 (2012); Ziemba, A., et al.: Chemother Res Pract 965826, 9 (2011); Beisler, J. A., et al.: J. Carbohyd. Chem 4, 281 (1977)<br></p>Formula:C7H14N4O5·C6H3N3O7Colore e forma:YellowPeso molecolare:463.31N-Formyl Valacyclovir
CAS:Prodotto controllato<p>Impurity Valaciclovir EP Impurity M<br>Applications N-Formyl Valacyclovir (Valaciclovir EP Impurity M) Valacyclovir (V085000) impurity.<br>References Furman, P., et al.: Antimicrob. Agents Chemother., 20, 518 (1981),<br></p>Formula:C14H20N6O5Colore e forma:White To Off-WhitePeso molecolare:352.355’-Deoxy-5-fluorouridine
CAS:Prodotto controllato<p>Impurity USP Capecitabine Related Compound B<br>Applications 5’-Deoxy-5-fluorouridine is a metabolite of the chemotherapeutic agent Capecitabine (C175650). 5’-Deoxy-5-fluorouridine is an antitumor agent efficient in tumors, cell lines or in fibroblasts tranformed by H-ras or trk oncogenes.<br>References Ingle, J., et al.: Cancer, 67, 886 (1991); Harvey, J., et al.: J. Clin. Oncol., 17, 1474 (1999); Asai-Sato, M., et al.: Int. J. Cancer, 115, 539 (2005); Rastelli, F., et al.: Tumori, 94, 370 (2008);<br></p>Formula:C9H11FN2O5Colore e forma:NeatPeso molecolare:246.19Acetyl Vitamin B12
CAS:<p>Applications Acetyl Vitamin B12 is a derivative of Vitamin B12 (V676020). Vitamin B12 gets converted by the body into its bioactive forms, methylcobalamin and cobamamide, which serve as enzyme cofactors. Severe deficiency may result in megaloblastic anemia and/or neurological impairment.<br>References Rickes, et al.: Science, 107, 396 (1948); Kirschbaum, J., et al.: Anal. Profiles Drug Subs., 10, 183 (1981); Grasbeck, R., et al.: Clin. Biochem., 17, 99 (1984)<br></p>Formula:C65H90CoN14O15PPurezza:>85%Colore e forma:NeatPeso molecolare:1397.405-Fluorouracil-13C,15N2
CAS:<p>Applications Labelled 5-FU, a potent antineoplastic agent in clinical use. Also an inhibitor of DNA synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rudy, B.C., et al.: Anal. Profiles Drug Subs., 2, 221 (1973), Miyashita, O., et al.: Chem. Pharm. Bull., 29, 3181 (1981), Hansen, R.M., et al.: Cancer Invest., 9, 637 (1991),<br></p>Formula:C313CH3F15N2O2Colore e forma:NeatPeso molecolare:133.06Capecitabine-2',3'-cyclic Carbonate
CAS:Prodotto controllato<p>Impurity Capecitabine EP Impurity F/ USP Capecitabine Related Compound C<br>Applications Capecitabine-2',3'-cyclic Carbonate (Capecitabine EP Impurity F) is a capecitabine related compound C is an impurity in Capecitabine (C175650), an antineoplastic agent. Capecitabine is a prodrug of Doxifluridine (D556750).<br>References Muss, H., et al.: New Eng. J. Med., 360, 2055 (2009), Takahashi, S., et al.: Drug Metab. Disposition, 37, 956 (2009), Saltz, L., et al.: J. Clin. Oncol., 27, 653 (2009), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),<br></p>Formula:C16H20FN3O7Colore e forma:NeatPeso molecolare:385.34Canagliflozin
CAS:Prodotto controllato<p>Applications Canagliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.<br>References Chao, E. et al.: Drug Fut., 36, 351 (2011); Sha, S. et al.: Diab. Obes. Metab., 13, 669 (2011); Kipnes, M.S.: Clin. Invest., 1, 145 (2011);<br></p>Formula:C24H25FO5SColore e forma:ColourlessPeso molecolare:444.52Zalcitabine
CAS:Prodotto controllato<p>Applications A pyrimidine nucleoside analogue with antiviral activity.<br>References van der Vliet, P.C. and Kwant, M.M.: Biochemistry, 20, 2628 (1981), Mitsuya, H., Broder, S.: Proc. Nat. Acad. Sci. USA, 83, 1911 (1986), Starnes, M.C., and Cheng, Y.: J. Biol. Chem., 262, 988 (1987),<br></p>Formula:C9H13N3O3Colore e forma:NeatPeso molecolare:211.22D-2’-Deoxyribofuranosyl-3-guanylurea(α/β-Mixture)
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Hydrolytic impurity of D226730 and A796950 (decitabine)<br>References Beisler, Jj.A., et al.: J. Med. Chem., 21, 204 (1978),<br></p>Formula:C7H14N4O4Colore e forma:NeatPeso molecolare:218.2105Lamivudine-13C1,d2
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Lamivudine-13C1,d2, is the labeled analogue of Lamivudine (L172502). A reverse transcriptase inhibitor. Antiviral.<br>References Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944), Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1997), Perry, C.M., et al.: Drugs, 53, 657 (1977),<br></p>Formula:C713CH9D2N3O3SColore e forma:White PowderPeso molecolare:232.26L-Valacyclovir Hydrochloride
CAS:Prodotto controllato<p>Applications Acyclovir (A192400) impurity. The L-Valine ester prodrug of Acyclovir.<br>References Beauchamp, L.M., et al.: Antiviral Chem. Chemother., 3, 157 (1992), Weller, S., et al.: Clin. Pharmacol. Ther., 54, 595 (1996), Lowance, D., et al.: N. Engl. J. Med., 340, 1462 (1999),<br></p>Formula:C13H20N6O4·ClHColore e forma:White To Off-WhitePeso molecolare:360.80Lamivudine
CAS:Prodotto controllato<p>Applications Lamivudine is a potent nucleoside reverse transcriptase inhibitor. Antiviral. Lamivudine has been used for treatment of chronic hepatitis B.<br>References Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944), Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1997), Perry, C.M., et al.: Drugs, 53, 657 (1977),<br></p>Formula:C8H11N3O3SColore e forma:WhitePeso molecolare:229.26Cobamamide
CAS:Prodotto controllato<p>Applications Cobamamide is an enzyme cofactor that can also regulate gene expression through RNA-base riboswitches.<br>References Ortiz-Guerrero, J.M., et. al.: P. Natl. Acad. Sci. USA, 108, 7565 (2011)<br></p>Formula:C72H100CoN18O17PColore e forma:NeatPeso molecolare:1579.585-Hydroxy-1-methyl-4-nitroimidazole Sodium Salt (>90%)
CAS:Prodotto controllato<p>Impurity Azathioprine BP Impurity E<br>Stability Light Sensitive<br>Applications 5-Hydroxy-1-methyl-4-nitroimidazole Sodium Salt is a degradation product of Azathioprine (A803350); an immunosuppressive antimetabolite that is also active as a disease modifying antirheumatic drug (DMARD).<br>References Mitrou, P.S., et al.: Arzneim.-Forsch., 29, 483, 662 (1979); Ding, T.L., et al.: Drug. Metab. Dispos., 7, 373 (1979); Chan, G.L.C., et al.: Pharmacotherapy, 7, 165 (1987); Sandborn, W.J., et al.: Scand. J. Gastroenterol., 33, Suppl. 225, 92 (1998)<br></p>Formula:C4H4N3NaO3Purezza:>90%Colore e forma:Light Yellow To YellowPeso molecolare:165.082-Deoxy-2,2-difluoro-D-erythro-ribofuranose-3,5-dibenzoate
CAS:Prodotto controllato<p>Applications Gemcitabine intermediate.<br>References Balzarini, J., et al.: Biochem. Pharmacol., 1988, 37, 2847 (1988), Hertel, L., et al.: Cancer Res., 50, 4417 (1990), Marquez, V., et al.: J. Med. Chem., 33, 978 (1990),<br></p>Formula:C19H16F2O6Colore e forma:Colourless To BrownPeso molecolare:378.32Emtricitabine
CAS:<p>Applications A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).<br>References FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. InfecSchinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: . Dis., 182, 599 (2000)<br></p>Formula:C8H10FN3O3SColore e forma:Light YellowPeso molecolare:247.255-Chlorouracil
CAS:Prodotto controllato<p>Impurity Fluorouracil EP Impurity E<br>Applications Used for the experimental and clinical treatment of neoplastic and viral diseases. Fluorouracil EP Impurity E.<br>References Yu, H., et al.: J. Biol. Chem., 268, 15935 (1993), Staleva, L., et al.: Mutat. Res., 370, 81(1996), Harris, V., et al.: J. Mol. Biol., 326, 1389 (2003)<br></p>Formula:C4H3ClN2O2Colore e forma:NeatPeso molecolare:146.532’,3’-Dideoxyinosine
CAS:Prodotto controllato<p>Applications 2’,3’-Dideoxyinosine is a purine analog (1) which used as an antiviral agent. Classed as an anti-retroviral drug used in the treatment of HIV in ART therapy, it also may increase acetaminophen related hepatotoxicity by enhancing mitochrondrial dysfunction (2).<br>References 1. Esplugues, J. et al.: AIDS. 2016 Jun 1;30(9):1341-51.2. Blas-Garcia, A. et al.: J. Antimicrob. Chemother. 2016 Apr;71(4):916-26<br></p>Formula:C10H12N4O3Colore e forma:NeatPeso molecolare:236.23Cladribine
CAS:<p>Applications It is a substituted purine nucleoside with antileukemic activity.<br>References Seto, S., et al.: J. Clin. Invest., 75, 377 (1985), Piro, L.D., et al.: N. Engl. J. Med., 322, 1117 (1990);<br></p>Formula:C10H12ClN5O3Colore e forma:White To Light YellowPeso molecolare:285.692'-Deoxyadenosine Monohydrate
CAS:Prodotto controllato<p>Applications 2'-Deoxyadenosine Monohydrate is used in the synthesis of 5'-modified 2'-deoxyadenosine analogues as anti-hepatitis C virus agents.<br>References Gordon, C., et al.: J. Med. Chem., 48, 1 (2005), Ikejiri, M., et al.: Bioorg. Med. Chem., 15, 6882 (2007),<br></p>Formula:C10H13N5O3·H2OColore e forma:NeatPeso molecolare:269.26Coenzyme Q9
CAS:<p>Applications Antibacterial and antioxidant for preventing and treating cancer.<br>References Itoh, K., et al.: J. Immunol., 170, 3688 (2003), Liu, A., et al.: J. Biol. Chem., 279, 53196 (2004), Wullaert, A., et al.: Biochem. Pharmacol., 72, 1090 (2006),<br></p>Formula:C54H82O4Colore e forma:YellowPeso molecolare:795.23Adenosine-15N
CAS:Prodotto controllato<p>Applications Nitrogen 15 labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010)<br></p>Formula:C10H1315NN4O4Colore e forma:NeatPeso molecolare:268.2354’,6-Diamidino-2-phenylindole Dihydrochloride
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications A cell-permeable DNA-binding dye. Binds preferentially to DNA rich in adenine and thymine. Used in flow cytometry for measuring nuclear DNA content or for sorting isolated chromosomes.<br>References Jpeeesen, C, and Nielsen, P.E.: Eur. J. Biochem., 182, 437 (1989), Li,J., et al.: J. Exp. Biol., 200, 1499 (1997), Zaitsev, E.N., and Kowalczykowsi, S.C.: Nucl. Acids Res., 26(2), 650 (1998), Germ, M., et al.: Biochem. Biophys. Res. Commun., 261, 452 (1999),<br></p>Formula:C16H15N5·2ClHColore e forma:Yellow PowderPeso molecolare:350.25Dapagliflozin C2 Epimer
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Dapagliflozin C2 Epimer is an intermediate used in the synthesis of Dapagliflozin (D185370), a sodium-glucose transporter 2 inhibitor.<br>References Majewski, A., et al.: Przemysl Chemiczny, 95, 1129 (2016); Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Formula:C21H25ClO6Colore e forma:NeatPeso molecolare:408.87(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile
CAS:<p>Applications (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile is a predominant metabolite of remdesivir with great potential for Covid-19 treatment.<br>References Yan, V. C., et al.: ACS Med. Chem., 11, 1361 (2020)<br></p>Formula:C12H13N5O4Colore e forma:NeatPeso molecolare:291.2627Triethyl Methanetricarboxylate
CAS:Prodotto controllato<p>Applications Triethyl Methanetricarboxylate is used in the synthesis of novel inhibitors of Hsp90. It is also used in the preparation of novel dihydroquinoline-3-carboxylic acids that function as HIV-1 integrase inhibitors.<br>References Day, J. et al.: Chem. A Eur. J., 16, 2758 (2010); Sechi, M. et al.: Bioorg. Med. Chem., 17, 2925 (2009);<br></p>Formula:C10H16O6Colore e forma:NeatPeso molecolare:232.235-Fluorouracil-6-d1
CAS:Prodotto controllatoFormula:C4H2DFN2O2Colore e forma:NeatPeso molecolare:131.08Ammeline-13C3 Hydrochloride
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Isotope labelled Ammeline (A633660), which s a metabolite of Melamine (1) (M208700), which acts as a non-protein nitrogen food additive (2). Also present in pet foods as well (3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br>References 1. Mast RW. et al.: Food Chem Toxicol. 1983 Dec;21(6):807-10.2. Ehling S. et al.: Food Addit Contam. 2007 Dec;24(12):1319-25.3. Vail T. et al.: J Anal Toxicol. 2007 Jul-Aug;31(6):304-12.<br></p>Formula:C3H5N5O·ClHColore e forma:NeatPeso molecolare:166.54Adenosine-5'-13C
CAS:Prodotto controllato<p>Applications Carbon 13 Labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010)<br></p>Formula:C913CH13N5O4Colore e forma:NeatPeso molecolare:268.24Penciclovir-d4
CAS:Prodotto controllato<p>Applications A deuterated version of Penciclovir, an antiviral.<br>References Weinberg, A., et al.: Antimicrob. Ag. Chemother., 36, 2037 (1992), McMeekin, J.R., et al.: Anal. Proc., 29, 178 (1992),<br></p>Formula:C102H4H11N5O3Colore e forma:NeatPeso molecolare:257.28Ribavirin Carboxylic Acid
CAS:<p>Impurity USP Ribavirin Related Compound A<br>Applications Ribavirin Carboxylic acid is an impurity of Ribavirin (R414475). Ribavirin impurity A.<br>References Lertora, J., et al.: Clin. Pharmacol. Ther., 50, 442 (1991), Connor, E., et al.: Antimicrob. Agents Chemother., 37, 532 (1993), Manns, M., et al.: Lancet, 358, 958 (2001),<br></p>Formula:C8H11N3O6Colore e forma:NeatPeso molecolare:245.19Adenosine-5',5''-d2
CAS:Prodotto controllato<p>Applications Labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010)<br></p>Formula:C10H11D2N5O4Colore e forma:White SolidPeso molecolare:269.26Abacavir Carboxylate
CAS:<p>Impurity Abacavir - In House Impurity<br>Stability Hygroscopic<br>Applications Abacavir Carboxylate (Abacavir - In House Impurity) is a major metabolite of Abacavir (A105000) in human urine and cerebrospinal fluid (1,2,3).<br>References (1) Hoetelmans, R., et al.: Pharm. World Sci., 19, 159 (1997) (2) Beach, J., et al.: Clin. Ther., 20, 2 (1998) (3) McDowell, J., et al.: Antimicrob. Agents Chemother., 43, 2855 (1999)<br></p>Formula:C14H16N6O2Colore e forma:NeatPeso molecolare:300.32Dapagliflozin Methyl Acetate
CAS:Prodotto controllato<p>Applications Dapagliflozin Methyl Acetate is the impurity of Dapagliflozin (D185370), which is a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Formula:C23H27ClO7Colore e forma:NeatPeso molecolare:450.909Famciclovir-d4
CAS:Prodotto controllato<p>Applications A deuterated prodrug of Penciclovir (P221500), which is used as an antiviral.<br>References Hodge, V.R.A., et al.: Antimicrob. Ag. Chemother., 33, 1765 (1989),<br></p>Formula:C142H4H15N5O4Colore e forma:Off-White To Light BeigePeso molecolare:325.36N6-Isopentenyladenosine
CAS:<p>Applications N6-Isopentenyladenosine has antiproliferative activity on MCF-7 breast cancer cells.<br>References Rajabi, M. et al.; DNA Cell Biol.; 29, 687 (2010)<br></p>Formula:C15H21N5O4Colore e forma:NeatPeso molecolare:335.365-Fluorodihydropyrimidine-2,4-dione-13C,15N2
CAS:Prodotto controllato<p>Applications A labelled metabolite of 5-Fluorouracil (F596000).<br>References Bocci, G., et al.: Eur. J. Clin. Pharmacol., 58, 593 (2002), Longley, D.B., Nature Rev. Cancer, 3, 330 (2003), Fischel, J., et al.: Anti-Cancer Drugs, 15, 969 (2004)<br></p>Formula:C313CH5F15N2O2Colore e forma:Off-White To Light BrownPeso molecolare:135.071-α-Methyl Dapagliflozin
CAS:<p>Stability Hygroscopic<br>Applications 1α-Methyl Dapagliflozin is an antidiabetic agent and intermediate of Dapagliflozin (D226255]), a sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011); Bernhardson, D. et al.: Org. Proc. Res. Dev., 18, 57 (2014);<br></p>Formula:C22H27ClO7Colore e forma:WhitePeso molecolare:438.90Dapagliflozin
CAS:<p>Stability Hygroscopic<br>Applications A sodium-glucose transporter 2 inhibitor.<br>References Kasichayanula, S. et al.: Diabetes, Obesity and Metabolism 13, 47 (2011)<br></p>Formula:C21H25ClO6Colore e forma:NeatPeso molecolare:408.87Ribavirin 5’-Monophosphate Dilithium Salt (90%)
CAS:Prodotto controllato<p>Applications A metabolite of Ribavirin.<br>References Allen, L.B., et al.: J. Med. Chem., 21, 742 (1978), Zimmerman, T., et al.: Biochem. Pharmacol., 27, 709 (1978), Page, T., et al.: Int. J. Biochem., 22, 379 (1990), Lin, C., et al.: Antimicrob. Agents Chemother., 47, 1395 (2003),<br></p>Formula:C17H19N4O9P·2LiPurezza:90%Colore e forma:Off-White To Light BeigePeso molecolare:468.21O6-Benzylguanine
CAS:Prodotto controllato<p>Applications An irreversible inhibitor of the mammalian DNA repair protein, O6-alkylguanine-DNA alkyltransferase. Assists in the protection against carcinogenic and therapeutic alkylating agents.<br>References Dolan, M.E., et al.: Proc. Natl. Acad. Sci. USA, 87, 5356 (1990), Goodtzova, K., et al.: Biochemistry, 33, 385 (1994), Elder, R.H., et al.: Biochem. J., 298, 231 (1994)<br></p>Formula:C12H11N5OColore e forma:NeatPeso molecolare:241.25α-Ribavirin (Ribavirin Impurity B)
CAS:Prodotto controllatoFormula:C8H12N4O5Colore e forma:NeatPeso molecolare:244.203'-Azido-3'-deoxythymidine β-D-glucuronide, Sodium Salt
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications A metabolite of the potent and selective inhibitor of HIV-1 replication, AZT.<br></p>Formula:C16H20N5O10·NaColore e forma:White To Light YellowPeso molecolare:465.35Cabotegravir O-β-D-Glucuronide
CAS:Prodotto controllato<p>Applications Cabotegravir O-β-D-Glucuronide is a metabolite of Cabotegravir (C050100), a long acting HIV-1 integrase inhibitor with action against a broad range of HIV subtypes.<br>References Yoshinaga, T. et al.: Antimicrob, Agents Chemother., 59, 397 (2015); Andrews, C. et al.: Sci. Transl. Med., 7, 270 (2015)<br></p>Formula:C25H25F2N3O11Purezza:>80%Colore e forma:NeatPeso molecolare:581.48Acyclovir Formacetal Dimer (>90%)
<p>Impurity Aciclovir EP Impurity R<br>Applications Acyclovir Formacetal Dimer is a dimer impurity of Acyclovir (A192400); an orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Also antiviral. (Aciclovir EP Impurity R)<br>References Collins, P., et al.: J. Antimicrob. Chemother., 5, 431 (1979); Matsumoto, H., et al.: Chem. Pharm. Bull., 36, 1153 (1988); Whitley, R.J., et al.: N. Engl. J. Med., 327, 782 (1992)<br></p>Formula:C17H22N10O6Purezza:>90%Colore e forma:NeatPeso molecolare:462.422’-Deoxyadenosine
CAS:<p>Applications 2prime-Deoxyadenosine is a nucleoside adenosine derivative with mutagenic properties.<br></p>Formula:C10H13N5O3Colore e forma:White To Off-WhitePeso molecolare:251.242N-Nitrosodiethylamine (100 ug/mL in Methanol)
CAS:Prodotto controllatoFormula:C4H10N2OColore e forma:Single SolutionPeso molecolare:102.14Famciclovir
CAS:Prodotto controllato<p>Applications Used as an antiviral. Prodrug of Penciclovir (P221500).<br>References Hodge, V.R.A., et al.: Antimicrob. Ag. Chemother., 33, 1765 (1989),<br></p>Formula:C14H19N5O4Colore e forma:Off-WhitePeso molecolare:321.33Coenzyme A Trilithium Salt
CAS:<p>Stability Hygroscopic<br>Applications A cofactor in enzymatic acetyl transfer reactions. It is the source of the phosphopantetheine group that is added as a prosthetic group to proteins such as acyl carrier protein and formyltetrahydrofolate dehydrogenase.<br>References Strickland K.C. et al.: J. Biol. Chem., 285, 1627 (2010); Elovson J. et al.: J. Biol. Chem., 243, 3603 (1968);<br></p>Formula:C21H33N7O16P3S·3LiColore e forma:NeatPeso molecolare:785.33Ribavirin-13C5
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Labelled Ribavirin (R414475). Purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.This compound is suitable for pyruvate dehydrogenase (PDH) related research.<br>References Fernandez, H., et al.: Eur. J. Epidemiol., 2, 1 (1986), Liao, H.J. and Stollar, V.: Antiviral Res., 22, 285 (1993), Honda, Y., et al.: Antimicrob. Agents Chemother., 38, 653 (1994), Reichard, O., et al.: Lancet, 351, 83 (1998)<br></p>Formula:C5C3H12N4O5Colore e forma:NeatPeso molecolare:249.17Flavine Adenine Dinucleotide Disodium Salt
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications The prosthetic group of certain flavoproteins including D-amino acid oxidase, glucose oxidase, glycine oxidase, fumaric hydrogenase, histaminase, and xanthine oxidase. Riboflavin kinase tumor necrosis factor receptor 1 NADPH oxidase.<br>References DeLuca, K., et al.: J. Biol. Chem., 223, 569 (1956), Yagi, K., et al.: Biochemistry, 19, 1553 (1980), Li, G., et al.: J. Phys. Chem., 112, 4573 (2008),<br></p>Formula:C27H31N9O15P2·2NaColore e forma:NeatPeso molecolare:829.516,6'-Thiobis-9H-purine
CAS:Prodotto controllato<p>Applications 6,6'-Thiobis-9H-purine is used in the study of the activity of topoisomerase IIα.<br>References Jensen, L.H., et al.: Molecular Pharmacology, 70, 1503 (2006);<br></p>Formula:C10H6N8SColore e forma:NeatPeso molecolare:270.27Adenosine-1'-13C
CAS:Prodotto controllatoFormula:CC9H13N5O4Colore e forma:White To Off-WhitePeso molecolare:268.234Adenosine 5'-Triphosphate Disodium Salt
CAS:<p>Stability Hygroscopic, Temperature Sensitive<br>Applications A metabolite of Adenosine (A280400), a multifunctional nucleoside triphosphate used in cells as a coenzyme of intracellular energy transfer. It transports chemical energy within cells for metabolism.<br>References Knowles, J., et al.: Annu. Rev. Biochem., 49, 877 (1980),<br></p>Formula:C10H14N5O13P3·2NaColore e forma:NeatPeso molecolare:569.16
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