2-Methoxystypandrone
CAS: 85122-21-0
Rif. TM-TN2775
| 5mg | Prezzo su richiesta | |
| 1ml*10 (DMSO) | Prezzo su richiesta |
Informazioni sul prodotto
- 2Methoxystypandrone
- 1,4-Naphthalenedione, 6-Acetyl-5-Hydroxy-2-Methoxy-7-Methyl-
- 2-Methoxy-6-acetyl-7-methyljuglone
- 6-Acetyl-5-hydroxy-2-methoxy-7-methyl-1,4-naphthalenedione
- Naphthoquinone (2-methylstipandrone
2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflammation and oxidative stress for preservation of BBB integrity. 2-Methoxystypandrone concomitantly promotes neurodevelopmental protein expression and endogenous neurogenesis through inactivation of GSK3β to enhance β-catenin signaling for upexpression of neuroprotective genes and proteins.2-Methoxystypandrone has anti-osteoclastogenic effect, could reflect the block of RANKL-induced association of TRAF6-TAK1 complexes with consequent decrease of IkappaB-mediated NF-kappaB and mitogen-activated protein kinases-mediated c-Fos activation pathways and suppression of NFATc1 and other gene expression, essential for bone resorption.
Proprietà chimiche
Richiesta tecnica su: TM-TN2775 2-Methoxystypandrone
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