Product Information
Name:Bragsin 2
Synonyms:
- 6-Methoxy-5-nitro-2-(trifluoromethyl)-4H-1-benzopyran-4-oneBragsin2
Brand:Biosynth
Description:Inhibitor of BRAG2-mediated activation of Arf GTP-ase. In vitro experiments showed that Bragsin2 inhibits the Arf GTP-ase activation that is mediated by a nucleotide exchange factor BRAG2 in a membrane-dependent manner. Bragsin2 interacts with the PH domain of BRAG2 protein as well as membrane, which prevents the activation of lipidated Arf. Bragsin2 affects the trans-Golgi network and was shown to affect the tumour sphere in breast cancer cell lines.
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Chemical properties
Molecular weight:289.16 g/mol
Formula:C11H6F3NO5
Purity:Min. 95%
Color/Form:Solid
Technical inquiry about: Bragsin 2
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