Product Information
- Thieno[3,2-d]pyrimidine-6-carboxamide
- 4-[4-[2-[(2,2-dimethyl-1-oxopropyl)amino]ethyl]-1-piperidinyl]
Inhibitor of pan-sirtuins (IC50 = 15, 10, 33 µM for SIRT1, 2 and 3 respectively), by binding to the active catalytic site. Selectivity for sirtuins was demonstrated when tested for activity on a panel of kinases, nuclear receptors, ion channels, transporters and GPCRs.
Chemical properties
Technical inquiry about: 3D-BT166491 Sirt-IN-1
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