AG 120
CAS: 1448347-49-6
Ref. 3D-FA145491
| 5mg | 141.00 € | ||
| 10mg | 193.00 € | ||
| 25mg | 357.00 € | ||
| 50mg | 475.00 € | ||
| 100mg | 710.00 € |
Estimated delivery in United States, on Tuesday 21 Jan 2025
Product Information
Name:
AG 120
Synonyms:
- Ivosidenib
- Glycinamide, N2-[1-(4-cyano-2-pyridinyl)-5-oxo-L-prolyl]-2-(2-chlorophenyl)-N1-(3,3-difluorocyclobutyl)-N2-(5-fluoro-3-pyridinyl)-, (2S)-
- Glycinamide, 1-(4-cyano-2-pyridinyl)-5-oxo-L-prolyl-2-(2-chlorophenyl)-N-(3,3-difluorocyclobutyl)-N2-(5-fluoro-3-pyridinyl)-, (2S)-
- (2S)-N-{(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl}-1(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide
Description:
Inhibits isocitrate dehydrogenase 1 (IDH-1) harbouring a gain of function mutation at R132, which causes impaired cellular differentiation via epigenetic modulation. By inhibiting mutant IDH1, synthesis of oncometabolite 2-hydroxyglutarate is reduced. This compound therefore has therapeutic potential in solid and haematological malignancies, such as acute myeloid leukemia (AML).
Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:
Chemical properties
Molecular weight:
582.96 g/mol
Formula:
C28H22ClF3N6O3
Purity:
Min. 95%
Color/Form:
White To Off-White Solid
MDL:
Melting point:
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Flash point:
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Concentration:
EINECS:
Merck:
HS code:
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