Product Information
Name:AG 120
Synonyms:
- Ivosidenib
Brand:Biosynth
Description:Inhibits isocitrate dehydrogenase 1 (IDH-1) harbouring a gain of function mutation at R132, which causes impaired cellular differentiation via epigenetic modulation. By inhibiting mutant IDH1, synthesis of oncometabolite 2-hydroxyglutarate is reduced. This compound therefore has therapeutic potential in solid and haematological malignancies, such as acute myeloid leukemia (AML).
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:582.96 g/mol
Formula:C28H22ClF3N6O3
Purity:Min. 95%
Color/Form:White To Off-White Solid
Technical inquiry about: AG 120
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