BMS 777607
CAS:
Ref. 3D-FB64961
10mg
486.00€
25mg
668.00€
50mg
920.00€
100mg
1,302.00€
250mg
2,323.00€
Product Information
Name:BMS 777607
Brand:Biosynth
Description:A potent Met kinase inhibitor (IC50 = 3.9 nM). Also inhibits Axl, Ron, and Tyro-3 (IC50 = 1.1, 1.8 and 4.3 nM, respectively). Anti-proliferative in Met-driven tumors in vitro and in vivo. Induces polyploidy in breast cancer cells and thereby chemoresistance.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:512.10629
Formula:C25H19ClF2N4O4
Purity:Min. 95%
InChI:InChI=1S/C25H19ClF2N4O4/c1-2-35-19-10-12-32(16-6-3-14(27)4-7-16)25(34)21(19)24(33)31-15-5-8-18(17(28)13-15)36-20-9-11-30-23(29)22(20)26/h3-13H,2H2,1H3,(H2,29,30)(H,31,33)
InChI key:InChIKey=VNBRGSXVFBYQNN-UHFFFAOYSA-N
SMILES:CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc(N)c2Cl)c(F)c1
Technical inquiry about: BMS 777607
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