1a,25-Dihydroxyvitamin D3

CAS: 32222-06-3

Ref. 3D-FC09794

Product Information

• Name: 1a,25-Dihydroxyvitamin D3
• Synonyms: 1a,25-DihydroxycholecalciferolCalcitriolRocaltrol, (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol, (1R,5Z)-5-[(2E)-2-[(1R,7aR)-1-(5-hydroxy-1,5-dimethyl-hexyl)-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexane-1,3-diol, (1S,3R)-9,10-secocholesta-5,7,10-triene-1,3,25-triol, (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triol, (1S,3R,5Z,7E,14xi)-9,10-secocholesta-5,7,10-triene-1,3,25-triol, (3β,5Z,7E)-9,10-Secocholesta-5,7,10(19)-trienetriol, (5Z,7E)-(1S,3R)-9,10-Secocholesta-5,7,10(19)-Triene-1,3,25-Triol, 1,25-Dihydroxycholecalciferol, 1,25-Dihydroxyvitamin D, 1,25-Dihydroxyvitamin D₃, 1,25-dihydroxyvitamin D3, 1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)-, 1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1R,3aS,7aS)-octahydro-1-[(1R)-5-hydroxy-1,5-dimethylhexyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)-, 1Alpha,25-Dihydroxycholecalciferol, 1a,25-Dihydroxyvitamin, 1alpha,25-Dihydroxyvitamin D3, 1α,25-(OH)2D3, 1α,25-(OH)₂D₃, 1α,25-Dihydroxyvitamin D3, 1α,25-Dihydroxyvitamin D₃, 1α,25-Hydroxyl-vitamin D₃, 9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol (1α,3β,5Z,7E)-, CALCITRIOL Calcitriol, Calcijex, Calcitriol, Dihydroxyvitamin D3, Dihydroxyvitamin D₃, Dn 101, Panbonis, Ro 21-5535, Rocaltrol, Silkis, Solbone P, Soltriol, Topitriol, Toptriol, Vitamin D3, 1a,25-Dihydroxy-

Description

Calcitriol is a steroid hormone, vitamin D metabolite and agonist of vitamin D receptor (VDR), also known as calcitriol receptor. It regulates absorption of calcium from intestine, resorption of bone calcium and calcium excretion via kidneys. This compound also controls cell cycle, promotes cell differentiation, triggers apoptosis and acts as anti-inflammatory factor within the tumor microenvironment. It has anti-proliferative effects in malignant epithelial cells and in tumour-derived endothelial cells (TDEC). Also, it is a potent inhibitor of retinal neoangiogenesis in vitro.

• Brand: Biosynth

Chemical properties

• Molecular weight: 416.32905
• Formula: C₂₇H₄₄O₃
• Purity: Min. 98 Area-%
• Color/Form: White Off-White Powder