Ebastine

CAS: 90729-43-4

Ref. 3D-FE22636

Product Information

• Name: Ebastine
• Synonyms: 1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(diphenylmethoxy)-1-piperidinyl]-1-butanoneEstivanEbastel, 1-(4-(1,1-Dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-1-butanone, 1-(4-Tert-Butylphenyl)-4-[4-(Diphenylmethoxy)Piperidin-1-Yl]Butan-1-One, 1-Butanone, 1-(4-(1,1-dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-, 4'-tert-Butyl-4-(4-(diphenylmethoxy)piperidino)butyrophenone, 4-Diphenylmethoxy-1-(3-(4-tert-butylbenzoyl)propyl)piperidine, Bastel, Ebastel, Ebastin, Ebastina, Ebastina [Spanish], Ebastine [USAN:INN], Ebastinum, Ebastinum [Latin], Erostin, Kestine, Las W-090, Rp 64305, Unii-Tqd7Q784P1

Description

Ebastine is a H1 receptor antagonist that belongs to the group of antihistamines. Ebastine inhibits histamine release from mast cells and basophils and may also have some anticancer activity. It has been shown to be effective in clinical trials, used to treat rhinitis and allergic symptoms such as itching and watery eyes. Ebastine is also non-sedating is not metabolized by cytochrome P450 enzymes but may affect their activity due to its binding affinity for proteins such as albumin and α1-acid glycoprotein.

• Brand: Biosynth

Chemical properties

• Molecular weight: 469.66 g/mol
• Formula: C₃₂H₃₉NO₂
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C32H39NO2/c1-32(2,3)28-18-16-25(17-19-28)30(34)15-10-22-33-23-20-29(21-24-33)35-31(26-11-6-4-7-12-26)27-13-8-5-9-14-27/h4-9,11-14,16-19,29,31H,10,15,20-24H2,1-3H3
• InChI key: InChIKey=MJJALKDDGIKVBE-UHFFFAOYSA-N
• SMILES: CC(C)(C)c1ccc(C(=O)CCCN2CCC(OC(c3ccccc3)c3ccccc3)CC2)cc1