Product Information
- 6-[(R)-Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinoneZarnestra
- (R)-(+)-R 115777
- (R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone
- 2(1H)-Quinolinone, 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-
- 6-[(R)-Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone
- 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one
- Tipifarnib Zarnestra
- Zarnestra
Tipifarnib is a peptide substrate that inhibits the enzyme DNA methyltransferase, which is responsible for maintaining the stability of DNA. It has been shown to be cytotoxic to myeloma cells and squamous cell carcinoma cells in vitro. Tipifarnib has minimal toxicity in vivo and does not have drug interactions. This drug has significant cytotoxicity in vitro and synergizes with other drugs such as p-gp inhibitors, egfr inhibitors, and toll-like receptor antagonists. Tipifarnib is biocompatible with mammalian cells, including human cells, and does not cause an increase in reactive oxygen species or lipid peroxidation.
Chemical properties
Technical inquiry about: 3D-FT28289 Tipifarnib
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