Fondaparinux sodium

CAS: 114870-03-0

Ref. 3D-OF04094

Product Information

• Name: Fondaparinux sodium
• Synonyms: Methyl O-2-deoxy-6-O-sulfo-2-(sulfoamino)-a-D-glucopyranosyl-(14)-O-b-D-glucopyranuronosyl-(14)-O-2-deoxy-3,6-di-O-sulfo-2-(sulfoami no)-a-D-glucopyranosyl-(14)-O-2-O-sulfo-a-L-idopyranuronosyl-(14)-2-deoxy-2-(sulfoamino)-a-D-glucopyranoside 6-(hydrogen s, IC 851589, SR 90107A, α-D-Glucopyranoside, methyl O-2-deoxy-6-O-sulfo-2-(sulfoamino)-α-D-glucopyranosyl-(1→4)-O-β-D-glucopyranuronosyl-(1→4)-O-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-α-D-glucopyranosyl-(1→4)-O-2-O-sulfo-α-L-idopyranuronosyl-(1→4)-2-deoxy-2-(sulfoamino)-, 6-(hydrogen sulfate), sodium salt (1:10), α-D-Glucopyranoside, methyl O-2-deoxy-6-O-sulfo-2-(sulfoamino)-α-D-glucopyranosyl-(1→4)-O-β-D-glucopyranuronosyl-(1→4)-O-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-α-D-glucopyranosyl-(1→4)-O-2-O-sulfo-α-L-idopyranuronosyl-(1→4)-2-deoxy-2-(sulfoamino)-, 6-(hydrogen sulfate), decasodium salt

Description

Fondaparinux sodium is an anticoagulant that is used to prevent deep vein thrombosis and pulmonary embolism. It is a low-dose group that can be used in patients with risk groups for bleeding. Fondaparinux sodium binds to antithrombin III, which prevents the formation of blood clots by inhibiting the coagulation cascade. The specific antidote for fondaparinux sodium is heparin, which is used to reverse the effects of fondaparinux sodium in case of overdose. Fondaparinux has been shown to inhibit antibody response against trifluoroacetic acid-coated erythrocytes in mice. Fondaparinux also increases the production of epidermal growth factor and basic fibroblast growth factor in vitro, which may be due to its anti-inflammatory properties. Fondaparinux sodium has been shown to have pharmacokinetic properties that vary according to age

• Brand: Biosynth

Chemical properties

• Molecular weight: 1,728.09 g/mol
• Formula: C₃₁H₄₃N₃Na₁₀O₄₉S₈
• Purity: Min. 95%
• Color/Form: White Off-White Powder