Product Information
BNC105 is a potent inhibitor of the epidermal growth factor receptor (EGFR) with inhibitory properties. It has been shown to inhibit tumor xenografts in mice and to decrease the size of solid tumours in humans. BNC105 binds to EGFR and blocks its interaction with the epidermal growth factor, thereby inhibiting protein synthesis and cell division. In addition, BNC105 also inhibits angiogenesis by blocking hydrogen bonds that are vital for this process. These anti-angiogenic properties may be responsible for the observed inhibition of tumor growth in vivo.
Chemical properties
Technical inquiry about: 3D-VMB77174 BNC105
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