Oltipraz
CAS: 64224-21-1
Ref. TM-T0153
5mg | 36.00 € | ||
10mg | 54.00 € | ||
25mg | 77.00 € | ||
50mg | 96.00 € | ||
100mg | 122.00 € | ||
200mg | 155.00 € | ||
1ml*10 (DMSO) | 54.00 € |
Product Information
- NSC 347901, RP 35972
- 3H-1,2-Dithiole-3-thione, 4-methyl-5-(2-pyrazinyl)-
- 3H-1,2-Dithiole-3-thione, 4-methyl-5-pyrazinyl-
- 4-Methyl-5-(2-pyrazinyl)-3H-1,2-dithiole-3-thione
- 4-Methyl-5-pyrazinyl-3H-1,2-dithiole-3-thione
- 4-methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione
- 5-(2-Pyrazinyl)-4-methyl-1,2-dithiole-3-thione
- Brn 0978110
- Ccris 4048
- Nsc 347901
- See more synonyms
- Oltipraz [INN]
- Oltiprazum
- Oltiprazum [INN-Latin]
- Rp 35972
- Unii-6N510Jul1Y
Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties. Oltipraz induces phase II detoxification enzymes, such as glutathione S transferase (GST) and NAD(P)H: quinone oxidoreductase 1 (NQO1). The induction of detoxification enzymes enhances the detoxification of certain cancer-causing agents, thereby enhancing their elimination and preventing carcinogen-induced DNA damages. Although the exact mechanism through which the anti-angiogenesis effect remains to be fully elucidated, oltipraz maybe able to modulate the expression of a number of angiogenic factors, thereby blocking the sustained and focal neovascularization in multiple tumor cell types.
Chemical properties
Technical inquiry about: TM-T0153 Oltipraz
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