HIF/HIF Prolyl-Hydroxylase
Hypoxia-Inducible Factor (HIF) is a transcription factor that plays a critical role in cellular responses to low oxygen levels (hypoxia). HIF activity is tightly regulated by HIF prolyl-hydroxylases, which target HIF for degradation under normoxic conditions. Inhibitors of HIF prolyl-hydroxylase can stabilize HIF, promoting the expression of genes involved in angiogenesis, erythropoiesis, and metabolism. These inhibitors are of great interest in treating conditions such as anemia, ischemic diseases, and cancer. At CymitQuimica, we offer HIF/HIF prolyl-hydroxylase inhibitors to support your research in hypoxia biology, cancer therapy, and metabolic regulation.
Found 150 products for "HIF/HIF Prolyl-Hydroxylase".
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SYP-5
CAS:SYP-5 is a novel inhibitor of HIF-1, suppresses tumor cells invasion and angiogenesis.Formula:C18H16O3SPurity:98.31%Color and Shape:SolidMolecular weight:312.38Roxadustat
CAS:Roxadustat (FG-4592) is an orally bioavailable, hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), with potential anti-anemic activity.Formula:C19H16N2O5Purity:99% - 99.88%Color and Shape:Yellow SolidMolecular weight:352.34Glucosamine hydrochloride
CAS:Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.Formula:C6H13NO5·HClPurity:99.77% - 99.96%Color and Shape:White SolidMolecular weight:215.63Chloramphenicol
CAS:Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Cost-effective and quality-assured.Formula:C11H12Cl2N2O5Purity:99.6% - 99.90%Color and Shape:White SolidMolecular weight:323.13Enarodustat
CAS:Enarodustat (JTZ-951) is an orally active factor inhibitor of prolyl hydroxylase (EC50: 0.22 μM) and has the potential for renal anemia treatment.Formula:C17H16N4O4Purity:99.73% - 99.75%Color and Shape:SolidMolecular weight:340.33Ref: TM-T15219
1mg37.00€2mg52.00€5mg74.00€1mL*10mM (DMSO)86.00€10mg109.00€25mg178.00€50mg295.00€100mg439.00€Glucosamine
CAS:Glucosamine (Chitosamine) is used as a dietary supplement. Glucosamine has pharmacological effects on osteoarthritis cartilage. High-Quality, Low-Cost!Formula:C6H13NO5Purity:99.68% - 99.8%Color and Shape:SolidMolecular weight:179.17PT2399
CAS:PT2399, an oral HIF-2 inhibitor, blocks HIF-2α/1β dimerization, showing strong in vivo antitumor effects.Formula:C17H10F5NO4SPurity:98.8% - 99.45%Color and Shape:White SolidMolecular weight:419.32Ref: TM-T12675L
1mg88.00€5mg212.00€1mL*10mM (DMSO)233.00€10mg318.00€25mg575.00€50mg848.00€100mg1,189.00€Albendazole
CAS:Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.Formula:C12H15N3O2SPurity:98.21% - 98.76%Color and Shape:Colorless Crystals SolidMolecular weight:265.33Hydroxycitric acid tripotassium hydrate
CAS:Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) effectively inhibits HIF, has antioxidation, anti-inflammation, and anti-tumor effects.Formula:C6H7K3O8Purity:99.85%Color and Shape:White Solid CrystallineMolecular weight:324.41Citric acid trilithium salt tetrahydrate
CAS:Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy ofFormula:C6H13Li3O11Purity:99.88%Color and Shape:White SolidMolecular weight:281.98Deferoxamine Mesylate
CAS:Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor.Formula:C26H52N6O11SPurity:94.68% - 99.91%Color and Shape:White SolidMolecular weight:656.79Tilorone dihydrochloride
CAS:Tilorone dihydrochloride is an orally active interferon inducer, and has antineoplastic and anti-inflammatory actions.Formula:C25H36Cl2N2O3Purity:98% - 99.86%Color and Shape:Orange SolidMolecular weight:483.47Minocycline hydrochloride
CAS:Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.Formula:C23H28ClN3O7Purity:99.71% - >99.99%Color and Shape:Yellow SolidMolecular weight:493.94HIF-2α-IN-2
CAS:HIF-2α-IN-2 is a hypoxia-inducible factor (HIF-2α) inhibitor (IC50: 16 nM in scintillation proximity assay).Formula:C17H13F2NO4SPurity:99.24%Color and Shape:White SolidMolecular weight:365.35Oltipraz
CAS:Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties.Formula:C8H6N2S3Purity:98.79% - 99.77%Color and Shape:SolidMolecular weight:226.34(-)-Hydroxycitric acid lactone
CAS:(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent.(-)-Hydroxycitric acid lactone was a potent inhibitor of ATP citrate lyase, whichFormula:C6H6O7Purity:99.85% - 99.91%Color and Shape:White SolidMolecular weight:190.11Amifostine
CAS:Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity.Formula:C5H15N2O3PSPurity:99.59% - 99.91%Color and Shape:White SolidMolecular weight:214.22Hydralazine hydrochloride
CAS:Hydralazine hydrochloride, an antihypertensive phthalazine, induces vasodilation and may inhibit tumor DNA methylation.Formula:C8H9ClN4Purity:99.85% - 99.86%Color and Shape:White SolidMolecular weight:196.64EHP-101
CAS:EHP-101 is a PPARγ/CB2 dual agonist with anti-inflammatory properties, inhibits fat formation, and combats diet-related obesity.Formula:C28H35NO3Purity:98.36%Color and Shape:SolidMolecular weight:433.58Ref: TM-T13289
1mg101.00€5mg178.00€1mL*10mM (DMSO)203.00€10mg295.00€25mg485.00€50mg677.00€100mg888.00€Vadadustat
CAS:Vadadustat is a novel, titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor in development for the treatment of anemia.Formula:C14H11ClN2O4Purity:99.02% - 99.80%Color and Shape:SolidMolecular weight:306.7
