Alvimopan
CAS: 156053-89-3
Ref. TM-T1242
1mg | 49.00 € | ||
2mg | 73.00 € | ||
5mg | 92.00 € | ||
10mg | 143.00 € | ||
25mg | 254.00 € | ||
50mg | 369.00 € | ||
100mg | 552.00 € | ||
500mg | 1,189.00 € | ||
1ml*10 (DMSO) | 92.00 € |
Product Information
- ADL 8-2698, LY 246736
- 2-([(2S)-2-([(3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]methyl)-3-phenylpropanoyl]amino)acetic acid
- Adl 8-2698
- Entereg
- Glycine, N-[(2S)-2-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]-
- Glycine, N-[2-[[4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]-, [3R-[1(S*),3α,4α]]-
- Ly 246736
- N-[(2S)-2-[[(3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]glycine
- N-{(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl}glycine
Alvimopan (LY 246736) is a synthetic trans-3, 4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity. Alvimopan is a selective and competitive antagonist at mu-opioid receptors, found in myenteric and submucosal neurons and the immune cells of the lamina propria in the human gut. Upon administration, this agent binds to mu-opioid receptors in the gut, thereby reversing opioid-related disturbances in gut motility. Alvimopan is approximately three to nine times more potent than naloxone.
Chemical properties
Technical inquiry about: TM-T1242 Alvimopan
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