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KRAS inhibitor-37

CAS:

Ref. TM-T201259

KRAS inhibitor-37
Targetmol

Product Information

Name:KRAS inhibitor-37
Brand:Targetmol
Description:KRAS inhibitor-37 (compound 2) is a potent inhibitor of KRAS, exhibiting low dissociation constants (KD) with various KRAS mutations: wild type (0.004 nM), G12D (0.041 nM), G12C (0.019 nM), and G12V (0.144 nM). This compound effectively inhibits cell proliferation, demonstrating half-maximal inhibitory concentrations (IC50) ranging from <2 nM to 14 nM in H358, SW620, and PANC08.13 cell lines. KRAS inhibitor-37 holds potential for cancer research applications.
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Chemical properties

Molecular weight:618.10
Formula:C32H33ClFN7O3
Color/Form:Solid

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