EGFR-IN-140
Ref. TM-T204256
Product Information
Name:EGFR-IN-140
Brand:Targetmol
Description:EGFR-IN-140 (Compound 31) is an inhibitor of EGFR, effectively targeting both wild-type EGFR and the EGFRL858R/T790M/C797S mutant, with Ki values of 0.95 nM and 2.1 nM, respectively. Additionally, it inhibits EGFRdel19/T790M/C797S in Ba/F3 cells with an IC50 of 56.9 nM and demonstrates antitumor activity in mouse models.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:524.633
Formula:C27H37FN8O2
Color/Form:Solid
Technical inquiry about: EGFR-IN-140
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