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GSK-3β inhibitor 24

Ref. TM-T204492

GSK-3β inhibitor 24
Targetmol

Product Information

Name:GSK-3β inhibitor 24
Brand:Targetmol
Description:GSK-3β inhibitor24 (Compound 41) is a potent GSK-3β inhibitor with an IC50 of 0.22 nM. It increases GSK-3β phosphorylation at the Ser9 site in a dose-dependent manner and inhibits tau protein hyperphosphorylation by reducing the abundance of p-tau-Ser396. The compound upregulates β-catenin and neurogenesis-related markers (GAP43 and MAP-2), demonstrating significant anti-Alzheimer's disease (AD) activity.
Notice:Our products are intended for lab use only. For any other use, please contact us.

Chemical properties

Molecular weight:434.446
Formula:C26H18N4O3
Color/Form:Solid

Technical inquiry about: GSK-3β inhibitor 24

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