Product Information
Name:Dual Cathepsin L/JAK-IN-1
Brand:Targetmol
Description:DualCathepsinL/JAK-IN-1 (Compound A8) serves as a dual inhibitor of Cathepsin L (CTSL) and JAK, exhibiting IC50 values of 0.68 μM for CTSL and 337.1 nM, 5.251 nM, 27.29 nM, and 172.6 nM for JAK1/2/3 and TYK2, respectively. This compound effectively prevents the activation of MAPK, NF-κB, and JAK/STAT signaling pathways, leading to significant anti-inflammatory therapeutic effects. DualCathepsinL/JAK-IN-1 is applicable in research on acute lung injury (ALI).
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:351.833
Formula:C19H18ClN5
Color/Form:Solid
Technical inquiry about: Dual Cathepsin L/JAK-IN-1
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