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EG31

CAS:

Ref. TM-T207269

EG31
Targetmol

Product Information

Name:EG31
Brand:Targetmol
Description:EG31 is an EGFR inhibitor that effectively suppresses the proliferation of triple-negative breast cancer (TNBC) cells by inhibiting the EGFR signaling pathway. It demonstrates a GI50 value of 498.90 nM for MDA-MB-231 cells and 740.73 nM for Hs578T cells, while also inducing apoptosis. Additionally, EG31 retains its antiproliferative activity against 5-fluorouracil (5-FU) resistant TNBC cells, with a GI50 of 519.5 nM. EG31 is applicable in research on TNBC resistance.
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Chemical properties

Molecular weight:671.25
Formula:C30H13Br2N3O6
Color/Form:Solid

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